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VGPSVTEDYDSSASRRLRKIALDAEIAGCRRCEGMNIAPATMSAPGYGCVSSPVALIGQSLCEKCMESQV PFTGGSGELIDESIQRAGREKEDVFISDAVHCHPPKNRSSHQHEIVDCSPYLHRELEIVRPRLVVALGRD GERVLTFFYPSARICEELFEIPRGRLPKGVPYIFHVKHPSWIQRQHDDNLEANYGRTCPRRSGGASTAKA RKRRARRDVASADVQFLDGYPVLSHAVPCRPAWCIPRVPES
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0027 | - | - | 100% (251) | glycosylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2236 | - | 7e-05 | 26.71% (161) | uracil-DNA glycosylase superfamily protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0590 | - | 9e-19 | 58.90% (73) | hypothetical protein MMAR_0590 |
| M. avium 104 | MAV_4094 | - | 9e-09 | 27.78% (180) | uracil DNA glycosylase superfamily protein |
| M. smegmatis MC2 155 | MSMEG_0265 | - | 6e-08 | 24.16% (178) | uracil DNA glycosylase superfamily protein |
| M. thermoresistible (build 8) | TH_1350 | - | 8e-11 | 27.11% (166) | uracil DNA glycosylase superfamily protein |
| M. vanbaalenii PYR-1 | Mvan_3202 | - | 4e-08 | 27.66% (141) | phage SPO1 DNA polymerase-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0027|M.ulcerans_Agy99 -------------------------------------MGPSVTEDYDSSA
MMAR_0590|M.marinum_M ---------------------------------------MSHAEERN---
TH_1350|M.thermoresistible__bu ----------------------------------------MAVTGAARFV
Mvan_3202|M.vanbaalenii_PYR-1 ----------------------------------------MTIVGAAEFV
MSMEG_0265|M.smegmatis_MC2_155 ------------------------------------------MAGAQDFV
MAV_4094|M.avium_104 ------------------------------------MTATSKAPGADRYL
Mflv_2236|M.gilvum_PYR-GCK MMTGPRARLPHPRTGDLFETPVRPGRGWPGDPATSRTAVASNPAQVTALA
MUL_0027|M.ulcerans_Agy99 SRRLRKIALDAEIAGCRRCEGMNIAPATMS----------------APGY
MMAR_0590|M.marinum_M -RGQRKALLDAEIKICRRCEGMNRPLETES----------------APGW
TH_1350|M.thermoresistible__bu PATRDLGELAEAVHACKGCD--LYVDATQA----------------VFGA
Mvan_3202|M.vanbaalenii_PYR-1 PQTRELSTLAAAAQSCRGCD--LFENASRA----------------VFGS
MSMEG_0265|M.smegmatis_MC2_155 PHTADLAELAAAAGECRGCG--LYRDATQA----------------VFGA
MAV_4094|M.avium_104 PEQRDIEALKHAAETCRGCS--LFADATQT----------------VFGN
Mflv_2236|M.gilvum_PYR-GCK AAAKNLRQLDAGVSVCRACPRLVEWREEAASVKRKSYADQPYWGRPAPGF
* *: * : . *
MUL_0027|M.ulcerans_Agy99 GCVSSPVALIGQSLCEK-CMESQVPFTGG-SGELIDESIQRAGREKEDVF
MMAR_0590|M.marinum_M GNLDSPVAIVGQSLCEQ-CMEPQEPFYEG-SGSLLNRTFAR---------
TH_1350|M.thermoresistible__bu GPGTAPMVMVGEQPGDR-EDTAGQPFVGP-AGRLLQRALDAAGIDRAEVY
Mvan_3202|M.vanbaalenii_PYR-1 GPVGARMMLVGEQPGDR-EDVAGEPFVGP-AGRLLDKALDEAGLPRAPVY
MSMEG_0265|M.smegmatis_MC2_155 GGRSARIMMIGEQPGDK-EDLAGLPFVGP-AGRLLDRALEAADIDRDALY
MAV_4094|M.avium_104 GHPGAPIMLVGEQPGDQ-EDRAGAPFVGP-AGRLLARALHDAGIDPGLTY
Mflv_2236|M.gilvum_PYR-GCK GSARPRILIVGLAPAAHGANRTGRVFTGDRSGDFLFASLHRSGLANQSTC
* . : ::* : . * :* :: ::
MUL_0027|M.ulcerans_Agy99 ISDAVHCHPPKN------------RSSHQHEIVDCSPYLHRE--LEIVRP
MMAR_0590|M.marinum_M --------------------------------------------LPIAK-
TH_1350|M.thermoresistible__bu VTNAVKHFTFT---RGRRLIH---KTPSRSDVVACRPWLIAE--LDSVRP
Mvan_3202|M.vanbaalenii_PYR-1 LTNAVKHFKFVPAERGTRRIH---KTPSRTEVVACRPWLIAE--MQAVEP
MSMEG_0265|M.smegmatis_MC2_155 VTNAVKHFKFTRAAGGKRRIH---KTPSRTEVVACRPWLIAE--MTSVEP
MAV_4094|M.avium_104 QTNAVKHFKFTR-KDGKRRIH---QKPGRTEIVACRPWLIAE--IEAVHP
Mflv_2236|M.gilvum_PYR-GCK TDSADGLELNDVRVAAAVRCAPPDNAPSPAERTTCAPWLDAEYRLTGTDV
: .
MUL_0027|M.ulcerans_Agy99 RLVVALGRDGERVLTFFYPSARICEELFEIPRGRLPKGVPYIFHVKHPSW
MMAR_0590|M.marinum_M --------------------------------------------------
TH_1350|M.thermoresistible__bu EVVVLLGATAAKSLLG------------PDFRLTAHRGEVLRLPAGDATV
Mvan_3202|M.vanbaalenii_PYR-1 AVVVLLGATAAKSLLG------------NAFRLTAHRGEVLSLPAETKPV
MSMEG_0265|M.smegmatis_MC2_155 DVVVLLGATAAKALLG------------NDFRVTQHRGEVLHVDDVPG--
MAV_4094|M.avium_104 RVIVCLGATAAQSLLG------------TSFRVSAQRGQPLKLPASPEVI
Mflv_2236|M.gilvum_PYR-GCK RVIVALGGFAWQVVLAMVR----------RTGGTVPVPAPKFGHAATAEL
MUL_0027|M.ulcerans_Agy99 IQRQHDDNLEANYGRTCPRRSGGASTAKARKRRARRDVASADVQFLDGYP
MMAR_0590|M.marinum_M -------------GPTVHHECGSLSPAQKS--------------------
TH_1350|M.thermoresistible__bu -GLGVDPLVVVTVHPSAVLRGRPGDRAEAFDALVADLEVAAGLMGS----
Mvan_3202|M.vanbaalenii_PYR-1 -G-GRDAKVVVTVHPSSVLRGPSQAREESFRSLVSDLRFAGELLDA----
MSMEG_0265|M.smegmatis_MC2_155 -----DPALVATVHPSSLLRGPKEERESAFAGLVDDLRVAADVRP-----
MAV_4094|M.avium_104 PDVAPEPVLVATVHPSSVLRDRSERHDEVYRLFVDDLRSARSALG-----
Mflv_2236|M.gilvum_PYR-GCK ATPRGAVTVLGCFHPSQQNTFTGRLTPDMMDAVFATARTLSK--------
: .
MUL_0027|M.ulcerans_Agy99 VLSHAVPCRPAWCIPRVPES
MMAR_0590|M.marinum_M --------------------
TH_1350|M.thermoresistible__bu --------------------
Mvan_3202|M.vanbaalenii_PYR-1 --------------------
MSMEG_0265|M.smegmatis_MC2_155 --------------------
MAV_4094|M.avium_104 --------------------
Mflv_2236|M.gilvum_PYR-GCK --------------------