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MADFVGAIDQGTTSTRFMIFDHAGNEVARHQLEHEQILPRPGWVEHNPVEIWERSSSAVQSALNAAKLQP SDLAALGVTNQRETTVVWNRRTGRPYYNAIVWQDTRTDSIAAALDRDGRGDVIREKAGLPPATYFAGGKI QWILENVPGVREDAEMGDALFGTTDSWLLWNLTGGTSGGVHVTDVTNASRTMLMDLETLDWDDELLGFFG VPRSMLPQIRPSSDPAGYGTTTSSRPYGGIPLTGDLGDQQAAMFGQVCFAPGEAKNTYGTGNFLLLNTGT TPVRSKNGLLTTVCYRLGDDAPVYALEGSIAVTGSAVQWLRDQMHVIDSAAESESLARLVDDNGGVYFVP AFSGLFAPYWRSDARGAIVGLSRYNTNAHLARATLESICYQSRDVAEAMEADSGVHLDVLKVDGGGVTVN DLCMQMQADILGVPVSRPVVAETTALGAAYAAGLAVGFWRNTDELRENWNESHRWDPQWTEEQRTTGYTG WRKAVERTLDWVDVQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6759 | glpK | - | 100% (505) | glycerol kinase |
| M. smegmatis MC2 155 | MSMEG_6229 | glpK | 0.0 | 80.24% (506) | glycerol kinase |
| M. smegmatis MC2 155 | MSMEG_6756 | glpK | e-157 | 53.80% (500) | glycerol kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3722c | glpKa | 2e-83 | 79.21% (178) | glycerol kinase |
| M. gilvum PYR-GCK | Mflv_1327 | glpK | 0.0 | 78.85% (506) | glycerol kinase |
| M. tuberculosis H37Rv | Rv3696c | glpK | 0.0 | 77.38% (504) | glycerol kinase |
| M. leprae Br4923 | MLBr_02314 | glpK | 0.0 | 76.79% (504) | glycerol kinase |
| M. abscessus ATCC 19977 | MAB_0382 | glpK | 0.0 | 75.84% (505) | glycerol kinase |
| M. marinum M | MMAR_5208 | glpK | 0.0 | 78.33% (503) | glycerol kinase GlpK |
| M. avium 104 | MAV_0406 | glpK | 0.0 | 77.58% (504) | glycerol kinase |
| M. thermoresistible (build 8) | TH_1719 | glpK | 0.0 | 75.69% (510) | PROBABLE GLYCEROL KINASE GLPK (ATP:GLYCEROL |
| M. ulcerans Agy99 | MUL_4281 | glpK | 0.0 | 77.93% (503) | glycerol kinase |
| M. vanbaalenii PYR-1 | Mvan_5467 | glpK | 0.0 | 79.21% (505) | glycerol kinase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6759|M.smegmatis_MC2_155 ------------MADFVGAIDQGTTSTRFMIFDHAGNEVARHQLEHEQIL
MAB_0382|M.abscessus_ATCC_1997 ------------MADFVASIDQGTTSTRAMIFNHRGEEVGRHQLEHQQLL
TH_1719|M.thermoresistible__bu ------------VAEFVAAIDQGTTSTRCMIFDHAGTEVGRHQLEHQQIM
Mflv_1327|M.gilvum_PYR-GCK ------------MADFVAAIDQGTTSTRCMIFDHDGAEVGRHQLEHEQIL
Mvan_5467|M.vanbaalenii_PYR-1 ------------MADFVAAIDQGTTSTRCMIFDHDGAEVGRHQLEHEQIL
MAV_0406|M.avium_104 ---------MAEFAEFIAAIDQGTTSTRCMIFDHQGAEVARHQLEHEQIL
MMAR_5208|M.marinum_M ---------MADSPDFVAAIDQGTTSTRCMIFDHQGAEIARHQLEHEQIL
MUL_4281|M.ulcerans_Agy99 ---------MADSPDFVAAIDQGTTSTRCMIFDHQGAEIARHQLVHEQIL
MLBr_02314|M.leprae_Br4923 ---------MAEFAEFIAAIDQGTTSTRCVIFDHNGAEVARHQLEHEQIL
Rv3696c|M.tuberculosis_H37Rv MSDAILGEQLAESSDFIAAIDQGTTSTRCMIFDHHGAEVARHQLEHEQIL
Mb3722c|M.bovis_AF2122/97 MSDAILGEQLAESSDFIAAIDQGTTSTRCMIFDHHGAEVARHQLEHEQIL
.:*:.:********* :**:* * *:.**** *:*::
MSMEG_6759|M.smegmatis_MC2_155 PRPGWVEHNPVEIWERSSSAVQSALNAAKLQPSDLAALGVTNQRETTVVW
MAB_0382|M.abscessus_ATCC_1997 PRAGWVEHNPVEIWERTWSVLATSLNVTGLSAGDLAAVGVTNQRETTLVW
TH_1719|M.thermoresistible__bu PQAGWVEHNPIEIWERTSAVIMSALNETRLSATDLAALGVTNQRETTLVW
Mflv_1327|M.gilvum_PYR-GCK PKAGWVEHNPVEIWERTGSVLATALNATKLATTDLAALGITNQRETSLVW
Mvan_5467|M.vanbaalenii_PYR-1 PRAGWVEHNPVEIWERTGSVLATALNKTKLSTSDLVALGITNQRETSLVW
MAV_0406|M.avium_104 PRAGWVEHDPIEIWERTSSVLTSVLNRANLSAENLAALGITNQRETTLVW
MMAR_5208|M.marinum_M PRAGWVEHNPVEIWERTASVLMSVLNATDLSPKNIAALGITNQRETTLVW
MUL_4281|M.ulcerans_Agy99 PRAGWVEHNPVEIWERTASVLMSVLNATDLSPKNIAALGITNQRETTLVW
MLBr_02314|M.leprae_Br4923 PRSGWVEHNPVEIWERTASVLMSVLNATNLSAKDIAALGITNQRETTLVW
Rv3696c|M.tuberculosis_H37Rv PRAGWVEHNPVEIWERTASVLISVLNATNLSPKDIAALGITNQRETTLVW
Mb3722c|M.bovis_AF2122/97 PRAGWVEHNPVEIWERTASVLISVLNATNLSPKDIAALGITNQRETTLVW
*:.*****:*:*****: :.: : ** : * . ::.*:*:******::**
MSMEG_6759|M.smegmatis_MC2_155 NRRTGRPYYNAIVWQDTRTDSIAAALDRDGRGDVIREKAGLPPATYFAGG
MAB_0382|M.abscessus_ATCC_1997 NRHTGRPYCNAIVWQDTRTDKIAAALDRDGRGDIIRRKAGLPPATYFSGG
TH_1719|M.thermoresistible__bu NKRTGRPYYNAIVWQDTRTDRIASALERDGRGEVIRQKAGLPPATYFSGG
Mflv_1327|M.gilvum_PYR-GCK NRHTGRPYYNAIVWQDTRTDRIASALDRDGRGDVIRRKAGLPPATYFSGG
Mvan_5467|M.vanbaalenii_PYR-1 NRHTGRPYYNAIVWQDTRTDRIASALDRDGRGDVIRQKAGLPPATYFSGG
MAV_0406|M.avium_104 NRKTGRPYYNAIVWQDTRTDRIASALDRDGRGQVIRRKAGLPPATYFSGA
MMAR_5208|M.marinum_M NKRTGRPYYNAIVWQDTRTDRIASALDRDGRGDVIRRKAGLPPATYFSGG
MUL_4281|M.ulcerans_Agy99 NKRTGRPYYNAIVWQDTRTDRIASALDRDGRGDVIRRKAGLPPATYFSGG
MLBr_02314|M.leprae_Br4923 NRNTGRPYCNAIVWQDTRTDRIAVALDRDGRGEVIRRKAGLPPATYFSGG
Rv3696c|M.tuberculosis_H37Rv NRHTGRPYYNAIVWQDTRTDRIASALDRDGRGNLIRRKAGLPPATYFSGG
Mb3722c|M.bovis_AF2122/97 NRHTGRPYYNAIVWQDTRTDRIASALDRDGRGNLIRRKAGLPPATYFSGG
*:.***** *********** ** **:*****::**.**********:*.
MSMEG_6759|M.smegmatis_MC2_155 KIQWILENVPGVREDAEMGDALFGTTDSWLLWNLTGGTSGGVHVTDVTNA
MAB_0382|M.abscessus_ATCC_1997 KLQWILENVEGVRRDAENGDALFGTPDSWVIWNLTGGVRSGVHVTDVTNA
TH_1719|M.thermoresistible__bu KLQWMLENVDGLRADAEKGEALFGTPDTWLVWNLTGGVRGGRHITDVTNA
Mflv_1327|M.gilvum_PYR-GCK KLQWLLENVDGLRADAANGDALFGTTDTWVLWNLTGGHRGGVHVTDVTNA
Mvan_5467|M.vanbaalenii_PYR-1 KLQWLLENVDGLRADAEKGDALFGTTDTWVLWNLTGGHRGGVHVTDVTNA
MAV_0406|M.avium_104 KLQWILDNVDGVREAAERGDALFGTADSWVLWQLTGGPRGGVHATDVTNA
MMAR_5208|M.marinum_M KLQWILENVDGVRAAAERGDALFGTPDTWVLWNLTGGPRGGVHVTDVTNA
MUL_4281|M.ulcerans_Agy99 KLQWILEDVDGVRAAAERGDALFGTPDTWVLWNLTGGPRGGVHVTDVTNA
MLBr_02314|M.leprae_Br4923 KLQWILENVDGVGAAAENGEALFGTPDTWLLWNLTGGPRGGVHVTDVTNA
Rv3696c|M.tuberculosis_H37Rv KLQWILENVDGVRAAAENGDALFGTPDTWVLWNLTGGPRGGVHVTDVTNA
Mb3722c|M.bovis_AF2122/97 KLQWILENVDGVRAAAENGDALFGTPDTWVLWNLTGGPRGG---------
*:**:*::* *: * *:*****.*:*::*:**** .*
MSMEG_6759|M.smegmatis_MC2_155 SRTMLMDLETLDWDDELLGFFGVPRSMLPQIRPSSDPAGYGTTTSSRPYG
MAB_0382|M.abscessus_ATCC_1997 SRTMLMNLETLDWDDELLSFFSIPRQMLPPIKASSPVEPFGFTTQLGPLG
TH_1719|M.thermoresistible__bu SRTMLMNLETLDWDDELLSFFGIPRAMLPEIKPSSYPQSYGITLDDGPVA
Mflv_1327|M.gilvum_PYR-GCK SRTMLMNLETLDWDDELLGFFDIPRQMLPEIRPSSSPQPYGVTVETGPAD
Mvan_5467|M.vanbaalenii_PYR-1 SRTMLMNLETLDWDDELLGFFDIPRQMLPEIRPSSSPEPHGVTVDWGPAD
MAV_0406|M.avium_104 SRTMLMDLETLDWDDELLSFFTIPRAMLPEIGPSSSPRPFGVTSDTGPAG
MMAR_5208|M.marinum_M SRTMLMNLETLDWDDELLSFFSIPRAMLPAIEPSSPLQPYGITQDTGPVG
MUL_4281|M.ulcerans_Agy99 SRTMLMNLETLDWDDELLSFFSIPRAMLPAIEPSSPLQPYGITQDTGPVG
MLBr_02314|M.leprae_Br4923 SRTMLMDLEKLDWDDELLSFFSIPRAMLPAIASSSPLQPYGVTLADGPVG
Rv3696c|M.tuberculosis_H37Rv SRTMLMDLETLDWDDELLSLFSIPRAMLPEIASSAPSEPYGVTLATGPVG
Mb3722c|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_6759|M.smegmatis_MC2_155 G-IPLTGDLGDQQAAMFGQVCFAPGEAKNTYGTGNFLLLNTGTTPVRSKN
MAB_0382|M.abscessus_ATCC_1997 GEVPIAGDLGDQQAAMVGQVCLNPGEAKNTYGTGNFLLLNTGEELVHSSN
TH_1719|M.thermoresistible__bu GQVPLTGILGDQQAAMVGQVCLSAGEAKNTYGTGNFLLLNTGENIVRSKN
Mflv_1327|M.gilvum_PYR-GCK GEIPITGILGDQQAAMVGQVCLDVGEAKNTYGTGNFLLLNTGEKIVRSDN
Mvan_5467|M.vanbaalenii_PYR-1 GEIPVTGILGDQQAAMVGQVCLDAGEAKNTYGTGNFLLLNTGENIVRSKN
MAV_0406|M.avium_104 GRIPITAVLGDQHAAMVGQVCLAEGEAKNTYGTGNFLLLNTGESIVRSEH
MMAR_5208|M.marinum_M GEVPITGMLGDQHAAMVGQVCLDAGEAKNTYGTGNFLLLNTGETIVRSSN
MUL_4281|M.ulcerans_Agy99 GEVPITGMLGDQHAAMVGQVCLDAGEAKNTYGTGNFLLLNTGETIVRSSN
MLBr_02314|M.leprae_Br4923 GEVPITGVLGDQHAAMVGQVCLDAGEAKNTYGTGNFLLLNTGEAIVRSGN
Rv3696c|M.tuberculosis_H37Rv GEVPITGVLGDQHAAMVGQVCLAPGEAKNTYGTGNFLLLNTGETIVRSNN
Mb3722c|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_6759|M.smegmatis_MC2_155 GLLTTVCYRLGDD-----APVYALEGSIAVTGSAVQWLRDQMHVIDSAAE
MAB_0382|M.abscessus_ATCC_1997 GLLTTVCYQFGDN-----KPVYALEGSIAVTGSAVQWLRDQLGIISGASQ
TH_1719|M.thermoresistible__bu GLITTVCYQFTGADGRPAEPVYALEGSIAVTGAAVQWLRDQLGIISGAAQ
Mflv_1327|M.gilvum_PYR-GCK GLLTTVCYQFGDS-----KPVYALEGSIAVTGSAVQWLRDQLGIISGASQ
Mvan_5467|M.vanbaalenii_PYR-1 GLLTTVCYQFGDA-----KPVYALEGSIAVTGSAVQWLRDQLGIISGAAQ
MAV_0406|M.avium_104 GLLTTVCYQFGDA-----KPVYALEGSIAVTGAAVQWLRDQLGIISGAAQ
MMAR_5208|M.marinum_M GLLTTLCYQFGDA-----KPVYALEGSIAVTGSAVQWLRDQLGIISGASQ
MUL_4281|M.ulcerans_Agy99 GLLTTLCYQFGDA-----KPVYALEGSIAVTGSAVQWLRDQLGIISGASQ
MLBr_02314|M.leprae_Br4923 GLLTTVCYQFGDA-----KPVYALEGSIAVTGSAVQWLRDQLGIISGAAQ
Rv3696c|M.tuberculosis_H37Rv GLLTTVCYQFGNA-----KPVYALEGSIAVTGSAVQWLRDQLGIISGAAQ
Mb3722c|M.bovis_AF2122/97 ----CACHRCNQR---------------------------QPDHVDGS--
*:: * :..:
MSMEG_6759|M.smegmatis_MC2_155 SESLARLVDDNGGVYFVPAFSGLFAPYWRSDARGAIVGLSRYNTNAHLAR
MAB_0382|M.abscessus_ATCC_1997 SEDLARQVEDNGGVYFVPAFSGLFAPYWRSDARGAIVGLSRFNTNAHLAR
TH_1719|M.thermoresistible__bu SESLARQVPDNGGVYFVPAFSGLFAPYWRSDARGAIVGLSRFNTNAHIAR
Mflv_1327|M.gilvum_PYR-GCK SESLARQVDDNGGVYFVPAFSGLFAPYWRSDARGAIVGLSRFNTNAHVAR
Mvan_5467|M.vanbaalenii_PYR-1 SESLARQVEDNGGVYFVPAFSGLFAPYWRSDARGAIVGLSRFNTNAHVAR
MAV_0406|M.avium_104 SESLARQVDDNGGVYFVPAFSGLFAPYWRSDARGAIVGLSRFDTNAHLAR
MMAR_5208|M.marinum_M SEALARQVSDNGGVYFVPAFSGLFAPYWRSDARGAIVGLSRFNNNAHLAR
MUL_4281|M.ulcerans_Agy99 SEALARQVSDNGGVYFVPAFSGLFAPYWRSDARGAIVGLSRFNNNAHLAR
MLBr_02314|M.leprae_Br4923 SESLARQVVDNGGVYFVPAFSGLFSPYWRSDARGAIVGLSRFNTNAHLAR
Rv3696c|M.tuberculosis_H37Rv SEALARQVPDNGGMYFVPAFSGLFAPYWRSDARGAIVGLSRFNTNAHLAR
Mb3722c|M.bovis_AF2122/97 ----------------------------RDAGLGRRAVVVVFDTSGHAAR
*. . * . : ::...* **
MSMEG_6759|M.smegmatis_MC2_155 ATLESICYQSRDVAEAMEADSGVHLDVLKVDGGGVTVNDLCMQMQADILG
MAB_0382|M.abscessus_ATCC_1997 ATLEAICYQSREVVEAMEADSGVRMEVLKVDGG-ITANKLCMQIQADTLG
TH_1719|M.thermoresistible__bu ATLEAICYQSRDVVDAMVADSGVRMESLKVDGG-ITANELCMQIQADVLG
Mflv_1327|M.gilvum_PYR-GCK ATLEAICYQSRDVVDAMAADSGVPLEVLKVDGG-ITANDLCMQIQADVLG
Mvan_5467|M.vanbaalenii_PYR-1 ATLEAICYQSRDVVDAMAADSGVHLEVLKVDGG-ITANDLCMQIQADVLG
MAV_0406|M.avium_104 ATLEAICYQSRDVVDAMAADSGVRLEVLKVDGG-ITGNDLCMQIQADVLG
MMAR_5208|M.marinum_M ATLEAICYQSRDVVDAMEADSGVRLEVLKVDGG-ITSNDLCMQIQADVLG
MUL_4281|M.ulcerans_Agy99 ATLEAICYQSRDVVDAMEADSGVRLEVLKVDGG-ITSNDLCMQIQADVLG
MLBr_02314|M.leprae_Br4923 ATLEAICYQSRDVVDAMAADSGVRLDVLKVDGG-ITSNDLCMQIQADVLG
Rv3696c|M.tuberculosis_H37Rv ATLEAICYQSRDVVDAMEADSGVRLQVLKVDGG-ITGNDLCMQIQADVLG
Mb3722c|M.bovis_AF2122/97 --------------DRIVGAVG----ALRCHAG----DRACRR-------
: : . * *: ..* : * :
MSMEG_6759|M.smegmatis_MC2_155 VPVSRPVVAETTALGAAYAAGLAVGFWRNTDELRENWNESHRWDPQWTEE
MAB_0382|M.abscessus_ATCC_1997 VDVVKPVVAETTALGAAYAAGLAVGFWKDADDLRRNWQEDERWSSSITDE
TH_1719|M.thermoresistible__bu VDVIKPVVSETTALGAAYAAGLAVGFWEDADDLRTNWQEGRRWTPQWTDE
Mflv_1327|M.gilvum_PYR-GCK VDVVKPVVAETTALGAAYAAGLAVGFWEGADDLRANWQEGRRWSPQWSDE
Mvan_5467|M.vanbaalenii_PYR-1 VDVVRPVVAETTALGAAYAAGLAVGFWDGADDLRANWQEDKRWSPTWSDD
MAV_0406|M.avium_104 VDVVRPVVAETTALGAAYAAGLAVGFWADPGELRANWREDKRWTPAWSDE
MMAR_5208|M.marinum_M VDVVRPVVAETTALGAAYAAGLAVGFWADPSDLRANWQEDKRWTPQWTDD
MUL_4281|M.ulcerans_Agy99 VDVVRPVVAETTALGAAYAAGLAVGFWADPSDLRANWQEDKRWTPQWTDD
MLBr_02314|M.leprae_Br4923 VDVVRSVVAETTALGSAYAAGLAVGFWAGPSDLRANWQEDKRWTPTWGED
Rv3696c|M.tuberculosis_H37Rv VDVVRPVVAETTALGVAYAAGLAVGFWAAPSDLRANWREDKRWTPTWDDD
Mb3722c|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_6759|M.smegmatis_MC2_155 QRTTGYTGWRKAVERTLDWVDVQ
MAB_0382|M.abscessus_ATCC_1997 KRAEGFAGWKKAVQRTLDGVDV-
TH_1719|M.thermoresistible__bu QREAGYRGWKKAVQRTLDWVDVG
Mflv_1327|M.gilvum_PYR-GCK QRAEGYAGWQKAVHRTLDWVDVE
Mvan_5467|M.vanbaalenii_PYR-1 QRAAGYAGWRKAVQRTMDWVDVD
MAV_0406|M.avium_104 QRAAGYAGWRKAVQRTLDWADVT
MMAR_5208|M.marinum_M QRAAGYAGWRKAVQRTLDWVDVS
MUL_4281|M.ulcerans_Agy99 QRAAGYAGWRKAVQRTLDWVDVS
MLBr_02314|M.leprae_Br4923 QRAAAYAGWRKAVQRTLDWVDVS
Rv3696c|M.tuberculosis_H37Rv ERAAGYAGWRKAVQRTLDWVDVS
Mb3722c|M.bovis_AF2122/97 -----------------------