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MVGRRTPEELADLLTVVGLTNQVANIIMQLALPGVGHGVNESRVVSGSPRRRPVKRARTTGQYLALAVMG SEDDRDAYRRELALVHAAVHSTPESPVRYSGNAQRLQKWVAACLFRYYLDQYTLLYGPLDTATLDRLTVA AAPLATGVNVRHSDWPQTWAQFTQYWEQQLDELSVAPEVREDLISLANLRFLEEAWGVPARIVTRPLGGL FSFGTRGSLPPRFRELMGWSWSGADQRRYELLLKALRVIDVVNPFALKCFYRAYLMDLRLRRRLNTVPDT PILGRLKVLDQPLEQTSAV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6722 | - | - | 100% (299) | hypothetical protein MSMEG_6722 |
| M. smegmatis MC2 155 | MSMEG_0613 | - | 9e-43 | 39.11% (271) | hypothetical protein MSMEG_0613 |
| M. smegmatis MC2 155 | MSMEG_3590 | - | 7e-41 | 39.01% (282) | hypothetical protein MSMEG_3590 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2261 | - | 2e-53 | 46.22% (251) | hypothetical protein Mb2261 |
| M. gilvum PYR-GCK | Mflv_0423 | - | 2e-45 | 38.81% (268) | hypothetical protein Mflv_0423 |
| M. tuberculosis H37Rv | Rv2237 | - | 2e-53 | 46.22% (251) | hypothetical protein Rv2237 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4329c | - | 7e-43 | 37.27% (271) | hypothetical protein MAB_4329c |
| M. marinum M | MMAR_3312 | - | 2e-55 | 44.85% (272) | hypothetical protein MMAR_3312 |
| M. avium 104 | MAV_2203 | - | 1e-54 | 44.28% (271) | hypothetical protein MAV_2203 |
| M. thermoresistible (build 8) | TH_1343 | - | 4e-62 | 48.71% (271) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1316 | - | 2e-55 | 44.85% (272) | hypothetical protein MUL_1316 |
| M. vanbaalenii PYR-1 | Mvan_0410 | - | 6e-47 | 42.64% (258) | hypothetical protein Mvan_0410 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2261|M.bovis_AF2122/97 --------------------------------------------------
Rv2237|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3312|M.marinum_M -------------MKRP---------------------------ATRVAD
MUL_1316|M.ulcerans_Agy99 -------------MKRP---------------------------ATRVAD
MAV_2203|M.avium_104 -------------MKRP---------------------------ATRVAD
TH_1343|M.thermoresistible__bu -------MRLRWGPPRH---------------------------PTRVVD
MAB_4329c|M.abscessus_ATCC_199 MVTIEQVSEAEAQLAGDGGPGTRSRRNEPVPPAAPLSPWWSWRRRPTVAD
Mvan_0410|M.vanbaalenii_PYR-1 -MTLDESVSAPVPLVER--PVSES--SVPAGPRARVS--------TRSDD
Mflv_0423|M.gilvum_PYR-GCK ------MNANRIQITRR----TARWSDDPV----------------RVGD
MSMEG_6722|M.smegmatis_MC2_155 ------------MVGRR--------------------------TPEELAD
Mb2261|M.bovis_AF2122/97 ------MLLPAANVIMQLAVPGVGYGVLESPVDSGNVYKHPFKRARTTGT
Rv2237|M.tuberculosis_H37Rv ------MLLPAANVIMQLAVPGVGYGVLESPVDSGNVYKHPFKRARTTGT
MMAR_3312|M.marinum_M LLNPAALLLPAANVIMQLSLPGVGYGVLESPVDSGNVYKHPFKRARTTGT
MUL_1316|M.ulcerans_Agy99 LLNPAALLLPAANVIMQLSLPGVGYGVLESPVDSGNVYKHPFKRARTTGT
MAV_2203|M.avium_104 LLNPAATLLPAANVIMQLSLPGVGYGVLESPVDSGNVYKHPFKRARTTGT
TH_1343|M.thermoresistible__bu LLNPAAALLPAANVIMQLALPGVGYGVLESPVDSGNVYKHPFKRARTTGT
MAB_4329c|M.abscessus_ATCC_199 NFMGLALLGGPANIIMQLARPGVGYGVVDSKVESGRADLHPIKRARTTFT
Mvan_0410|M.vanbaalenii_PYR-1 GMLGLGLLAGPANVIMQLARPGVGYGVLESRVESGRIDRHPVKRARTTFT
Mflv_0423|M.gilvum_PYR-GCK AMDFWSFAAGAANVIMQLSRPGVGYGVVESKVDSGNLMKHPWKRARTTFQ
MSMEG_6722|M.smegmatis_MC2_155 LLTVVGLTNQVANIIMQLALPGVGHGVNESRVVSGSPRRRPVKRARTTGQ
**:****: ****:** :* * ** :* ******
Mb2261|M.bovis_AF2122/97 YLAVATIGTESDRALIRGAVDVAHRQVRSTASSPVSYNAFDPKLQLWVAA
Rv2237|M.tuberculosis_H37Rv YLAVATIGTESDRALIRGAVDVAHRQVRSTASSPVSYNAFDPKLQLWVAA
MMAR_3312|M.marinum_M YLAVATIGSESDRALIRAAVDSVHRQVRSTSSSPVSYNAFDPKLQLWVAA
MUL_1316|M.ulcerans_Agy99 YLAVATIGSESDRALIRAAVDSVHRQVRSTSSSPVSYNAFDPKLQLWVAA
MAV_2203|M.avium_104 YLAAATIGTDYDRALICAAVDVAHRQVRSRPSSPVSYNAFDPKLQLWVAA
TH_1343|M.thermoresistible__bu YLAAATMGTEADRRLIRDAVNTAHAQVRSTPTSPVSYNAFDPKLQLWVAA
MAB_4329c|M.abscessus_ATCC_199 FLAVATLGTPEQKAAFRKATNRAHAQVHSQPGDKVQYNAFDPELQKWVAV
Mvan_0410|M.vanbaalenii_PYR-1 YLAVSTNGTPEQQAAFRRAVNRAHAQVFSTDESPVKYHAFDKDLQLWVGA
Mflv_0423|M.gilvum_PYR-GCK YLAVAIFGSDDDRAAFRAAVDEAHRHVKSTPSSPVRYNAFDRDLQMWVAA
MSMEG_6722|M.smegmatis_MC2_155 YLALAVMGSEDDRDAYRRELALVHAAVHSTPESPVRYSGNAQRLQKWVAA
:** : *: :: .* * * . * * . ** **..
Mb2261|M.bovis_AF2122/97 CLYRYFVDQHEFLYGPLEDATADAVYQDAKRLGTTLQVPEGMWPPDRVAF
Rv2237|M.tuberculosis_H37Rv CLYRYFVDQHEFLYGPLEDATADAVYQDAKRLGTTLQVPEGMWPPDRVAF
MMAR_3312|M.marinum_M CLYRYFVEQHEFLHGPLDDGAADSVYLDAKRLGTTLQVPERMWPPDRIAF
MUL_1316|M.ulcerans_Agy99 CLYRYFVEQHEFLHGPLDDGAADSVYLDAKRLGTTLQVPERMWPPDRIAF
MAV_2203|M.avium_104 CLYRYFVDQHEFLHGPLDEASADAVYRDAARLGTTLQVPERMWPPDRAAF
TH_1343|M.thermoresistible__bu CLFRYYIDMHEFLYGPLDDADADAVYRDARTLGTTLQVREDMWPPDRQAF
MAB_4329c|M.abscessus_ATCC_199 CLYKGFVDVYEAFVGPLTGETAERCLQEGAVMGTTLQMPLAMWPKSCAEF
Mvan_0410|M.vanbaalenii_PYR-1 CLYKGVVDVHRLFVGEMDEETADRLYLQGRALATMLQVPEDMWPADRAAF
Mflv_0423|M.gilvum_PYR-GCK CLFVGLEDTYQLLRGEMTAEQADHFYASAWTLGTTLQVTEDQWPPTRADF
MSMEG_6722|M.smegmatis_MC2_155 CLFRYYLDQYTLLYGPLDTATLDRLTVAAAPLATGVNVRHSDWPQTWAQF
**: : : : * : : . :.* ::: ** *
Mb2261|M.bovis_AF2122/97 DEYWKRSLDGLQIDAPVREHLRGVASVA----FLPWPLRAVAGPFN---L
Rv2237|M.tuberculosis_H37Rv DEYWKRSLDGLQIDAPVREHLRGVASVA----FLPWPLRAVAGPFN---L
MMAR_3312|M.marinum_M VEYWKRSLDELHIDPPVREHLRGVASMA----FLPWPLRALAGPFN---L
MUL_1316|M.ulcerans_Agy99 DEYWKRSLDELHIDPPVREHLRGVASMA----FLPWPLRALAGPFN---L
MAV_2203|M.avium_104 DEYWKRSLDELRIDPPVREHLHGVASLA----FLPWPLRVLAGPFN---L
TH_1343|M.thermoresistible__bu DEYWKRSLDELRIDPPVREHLLGVAAMA----FLPTPVSATLGRFN---L
MAB_4329c|M.abscessus_ATCC_199 DEYWAQSMDLVHIDDHVRPYLYRIAS---ASIAVPPFMRGPVGAFS---R
Mvan_0410|M.vanbaalenii_PYR-1 DRYWQESLDDVHIDDTVREFLYPIAATRLRGLALPGPLQRQTEKLA---L
Mflv_0423|M.gilvum_PYR-GCK DRYWDEACGQVAMDDVVRSYLLDLVDLR----MINPVLGIPFRPLL---K
MSMEG_6722|M.smegmatis_MC2_155 TQYWEQQLDELSVAPEVREDLISLANLRFLEEAWGVPARIVTRPLGGLFS
.** . . : : ** * :. :
Mb2261|M.bovis_AF2122/97 FATTGFLAPEFRAMMQLEWSQAQQRRFEWLLSVLRLADRLIPHRAWIFVY
Rv2237|M.tuberculosis_H37Rv FATTGFLAPEFRAMMQLEWSQAQQRRFEWLLSVLRLADRLIPHRAWIFVY
MMAR_3312|M.marinum_M FATTGFLAPEFRAMMRLDWSQSQQSRFEWLLAALRLADRLIPHRAWILIY
MUL_1316|M.ulcerans_Agy99 FATTGFLAPEFRAMMRLDWSQSQQSRFEWLLAALRLADRLIPHRAWILIY
MAV_2203|M.avium_104 FATTGFLAPEFREMMQLDWTPGQQRRFGWLLFSLRLADRLIPHGVWILGY
TH_1343|M.thermoresistible__bu FATTGFLPPEFRDQMKLDWSGAQQRTFERLLAALRIADRVIPREAWQFGY
MAB_4329c|M.abscessus_ATCC_199 FITTGFLPQRFRDEMGFAWDPSRERMFRWLLAVLGLAARLLPNGLRRFPF
Mvan_0410|M.vanbaalenii_PYR-1 LITTGFLPQRFREEMQLPWDAGQQRRFDRLMAALRAVNSVSPKFVRQFPF
Mflv_0423|M.gilvum_PYR-GCK FLTAGFLAPVFRDALGLTWGDGRQRLFERLFLCVAFVNRFIPGFLRQGGS
MSMEG_6722|M.smegmatis_MC2_155 FGTRGSLPPRFRELMGWSWSGADQRRYELLLKALRVIDVVNPFALKCF-Y
: * * *. ** : * . : : *: : . *
Mb2261|M.bovis_AF2122/97 QLYLWDMRFRARH---------GRRIV-----------
Rv2237|M.tuberculosis_H37Rv QLYLWDMRFRARH---------GRRIV-----------
MMAR_3312|M.marinum_M QLYLWDMRFRARR---------GWRVV-----------
MUL_1316|M.ulcerans_Agy99 QLYLWDMRFRARR---------GWRVV-----------
MAV_2203|M.avium_104 RIYLWDMRSRARR---------GRRVV-----------
TH_1343|M.thermoresistible__bu RLYLWDMRIRARL---------GRRVV-----------
MAB_4329c|M.abscessus_ATCC_199 NALMLDLDWRIRT---------GRPLV-----------
Mvan_0410|M.vanbaalenii_PYR-1 NVLLKDLDWRVRT---------GRPLV-----------
Mflv_0423|M.gilvum_PYR-GCK HVLLADVRMRVRR---------HRQLV-----------
MSMEG_6722|M.smegmatis_MC2_155 RAYLMDLRLRRRLNTVPDTPILGRLKVLDQPLEQTSAV
. : *: * * *