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VSTAFFNGEELDALAGDEITVRLHHPVHPHEPLRFVLAAGQPVPLRRMLPALESMDLEVINEHTTSPTRD DGSVCHVYELVLDPGTAGAQGFARDWNRAQDQICDTFRAIWSDRIEADRLNALIPTAGLDWRQVAVLRSY SRYLRQLPLPYGQGRIQQVLLDNPAATTAVVALFEARFARQSVSSGAVRERDMAAADQRLEAEIDRVVHI DADRILRTYRSLVNATVRTNAFTPEALTPKAPYLVHKFDASAIDELPQPRPLSEIFVYAPQFEGLHLRFG LVARGGLRWSDRHDDYRTEVLGLVKAQAVKNAMIVPAGAKGVFVVKPPSSSRTEGMRCYKQFVSALLDVV DNAVSDEPPAPEGVVCHDGPDPYLVVAADKGTATFSDIANAVALDRGYWLGDAFASGGSAGYDHKAMGIT ARGAWVSGDSHLQELGIDSATDEFRVVGIGDMSGDVFGNGMLLRRGIRLVAAFDHRHIFVDPDPSTQAAY RERQRLFALARSSWDDYDRAVISAGGGVWPRTAKRIPVSEQMRATLGISGEITSVTPTELIRHILCAPVD LLFNGGIGTYIKASDEQHGDVGDKVNDNVRVDANQVRAKVIVEGGNLGVSPRGRIEFARNGGYINTDAID NAAGVDCSDHEVNLKILLAGRIRGTERNTLLADMTDEVAAHVLANNRAHNRLLRDARSNAAQMVSVHARM TTALERDGLVRELEHLPSAEEFAAMASAGEGLTRPQLATLMAHTKLGLKADLLAADDFDDPYFTAALHRY FPATLRRRLGDRLTEHPLRREIVATAVVNHVLATSGLTYAFRLVEETDAGTSEIVRAHAVASEVFELDAL WHDIHAAGLSPQLTDSLIIEGRRLLDRASRWFLLNRPQPLSIAAEAARFQAVAMLRGKLSEMLRGDELLT VTRLHDEYVAQGVPADIARRLSEALYSYSLLDIIDIAHAHSEDATRLAHIYFELSAHLGVDGLLYAVSSL PRNGRWNALARLALREDLYRSLRDLARDVYRMVGPHTDNVDVIAEFEAYNRPRIERARRTLREVLATENP DLAMLSVATAQVRRLTTAGG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6272 | - | - | 100% (1070) | NAD-glutamate dehydrogenase |
M. smegmatis MC2 155 | MSMEG_4699 | - | 0.0 | 51.14% (1056) | NAD-glutamate dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2503c | gdh | 0.0 | 53.02% (1058) | NAD-dependent glutamate dehydrogenase |
M. gilvum PYR-GCK | Mflv_2569 | - | 0.0 | 51.98% (1058) | NAD-glutamate dehydrogenase |
M. tuberculosis H37Rv | Rv2476c | gdh | 0.0 | 53.02% (1058) | NAD-dependent glutamate dehydrogenase |
M. leprae Br4923 | MLBr_01249 | - | 0.0 | 51.66% (1053) | hypothetical protein MLBr_01249 |
M. abscessus ATCC 19977 | MAB_1561 | - | 0.0 | 52.19% (1050) | NAD-dependent glutamate dehydrogenase |
M. marinum M | MMAR_3829 | gdh | 0.0 | 52.56% (1054) | NAD-dependent glutamate dehydrogenase Gdh |
M. avium 104 | MAV_1696 | - | 0.0 | 52.36% (1058) | NAD-glutamate dehydrogenase |
M. thermoresistible (build 8) | TH_0917 | - | 0.0 | 54.56% (889) | PROBABLE NAD-DEPENDENT GLUTAMATE DEHYDROGENASE GDH (NAD-GDH) |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_4069 | - | 0.0 | 50.95% (1056) | NAD-glutamate dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2503c|M.bovis_AF2122/97 ---------------MTIDPGAKQDVEAWTTFTASADIPDWISKAYIDSY Rv2476c|M.tuberculosis_H37Rv ---------------MTIDPGAKQDVEAWTTFTASADIPDWISKAYIDSY MMAR_3829|M.marinum_M ---------------MTIDPGAKQDVGAWTAFTQPADIPDWISQAYLDSY MAV_1696|M.avium_104 MFERIDNRRQLGAIGMTIDPRAQQDLKPWTTFTRQQDIPEWISKAYVESY MLBr_01249|M.leprae_Br4923 ---------------MTIDPGATHVAELCTTFTQGADVPDWISKAYIDSY Mflv_2569|M.gilvum_PYR-GCK ---------------MSLNPGAVN---GATG-AVGAEMVERLIPAYLATY Mvan_4069|M.vanbaalenii_PYR-1 ---------------MSLNPGAIN---GSVGPEVSSEVIDRLLPAYLATY TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 ---------------MTVNTGTTTSENTPSANGSGVPTIEALTAAFSGAR MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 -RGPRDDS--SEATKAAEASWLPASLLTPAMLGAHYRLGRHRAAGESCVA Rv2476c|M.tuberculosis_H37Rv -RGPRDDS--SEATKAAEASWLPASLLTPAMLGAHYRLGRHRAAGESCVA MMAR_3829|M.marinum_M QRRGEEDS--QASQRAAEA---AASVVTPAMLSAHYRLGQHRPIGESRVA MAV_1696|M.avium_104 RGPHSDES--GGAEAGPIDLTVPTAIVTPAMLSAHYRLGLHRPDGESRVA MLBr_01249|M.leprae_Br4923 RGSHGDVR--EAPETSRVN---PNALVTPAMLSAHYRLGQCRPNGRNCVR Mflv_2569|M.gilvum_PYR-GCK RGPHGGAPGADAAVTGPLRRH-DDGLDTTALVEAQCRLAGTRLPGATNVA Mvan_4069|M.vanbaalenii_PYR-1 RGPHGGAPGAESAVTGPLRRQGTDTVNGPALVAAHYRLGAQRSPGATRVA TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 YMGEMDWD---EPLEPDGHAAPAAPPVREALMRALLRLAARRQPHEIAMA MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 VYRADDPAGFGPALQVVAEHGGMLMDSVTVLLHRLGIAYAAILTPVFDVH Rv2476c|M.tuberculosis_H37Rv VYRADDPAGFGPALQVVAEHGGMLMDSVTVLLHRLGIAYAAILTPVFDVH MMAR_3829|M.marinum_M VYPADDPVGFGPALQVVTEHGSMLMDSVTVLLHRLGVGYTTIMTPVFEVH MAV_1696|M.avium_104 VYPADDPAGFGPALQVVTDHGGMLMDSVTVLLHRLGVPYTAIMTPVFDVH MLBr_01249|M.leprae_Br4923 VYPADDPAGFGPALQIVTDHGGMVMDSITVLLHRLGVTYTAMMTPVFMVL Mflv_2569|M.gilvum_PYR-GCK VYPGDEATGFGPALQIVTDNASLLMDSVTVLLHRIGVAYTAIMNPGFRVR Mvan_4069|M.vanbaalenii_PYR-1 VHAADVEGGFGPALQVVTDNAAILMDSITVLLHRIGVAYTAIMNPVFRVR TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 TYRNGDDAGLGTALQLVTDYTPLLTESITVLLRRQGVAIVDLMDPVFSVE MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 RSPTGELLRIEPKAEGTSP-----HLGEAWMHVALSPAVDHKGLAEVERL Rv2476c|M.tuberculosis_H37Rv RSPTGELLRIEPKAEGTSP-----HLGEAWMHVALSPAVDHKGLAEVERL MMAR_3829|M.marinum_M RGPTGELQRVEPKSLDASP-----YVGEAWIHVQLSPTVEAKALAEVEQL MAV_1696|M.avium_104 RSPDGDLLSLEPKPQGAPQ-----YAGEAWIHVQLLPSVDSKGLTEAERL MLBr_01249|M.leprae_Br4923 RSPTGELLGVEPRASSTSHSIEGTWVGEVWIYIQLLPAVDSKSLAEVEQL Mflv_2569|M.gilvum_PYR-GCK RGGAGELLDVAPVSDASFSDG----VDETWVHVQLAGSVDRHALAEAEEL Mvan_4069|M.vanbaalenii_PYR-1 RGAGGELQDIAPASDATFVDG----VDETWVHVQLADSVDRRALAEAEEL TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 RAADGTLLSAAPVDHPQSDTAP---NAECWIHLQLPPSIDAERLAFIETQ MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 LPKVLADVQRVATDATALIATLSELAGEVESNAG-GRFSAPDRQDVGELL Rv2476c|M.tuberculosis_H37Rv LPKVLADVQRVATDATALIATLSELAGEVESNAG-GRFSAPDRQDVGELL MMAR_3829|M.marinum_M LPKVLADVQRVAKDAPAMIATLSELAVAVDSDRE-GHYAAPDHQEVAALL MAV_1696|M.avium_104 LPKVLADVQQVASDASALIAVLDELAAAVEANRD-NHFSAPDRDDVAALL MLBr_01249|M.leprae_Br4923 LPRTLVDVQRVAADAAALNATLSGLAADVKTNKE-GHFSASDRDDVAALL Mflv_2569|M.gilvum_PYR-GCK LPKVLADARQVALDSTDMAAALRILAAELDGDTG-RRFPSPDRKDVAALL Mvan_4069|M.vanbaalenii_PYR-1 LPRVLADARQVALDSTGMAAALRTLAAELDSDPG-RRFPSPDRKDVAALL TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 LPHTLEDGSHVAADTDAMRDAVIELASDLDAAPGNARFSSAELTEVANLL MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 RWLGDGNFLLLGYQRCRVADGMVYGEGSSGMGVLRGRTGSRPRLTDDDKL Rv2476c|M.tuberculosis_H37Rv RWLGDGNFLLLGYQRCRVADGMVYGEGSSGMGVLRGRTGSRPRLTDDDKL MMAR_3829|M.marinum_M RWLGNGNFLLLGYQPCEVDDGMVLGDGSTGLGVLRARTGTRPRLTDETKL MAV_1696|M.avium_104 RWLGNGNFLLLGYQRCRVHDGLVSGDGSPGLGVLRTRTGSRPRLTDDDRL MLBr_01249|M.leprae_Br4923 HWLGNGNFLLLGYQRCRVHYGLVSCDRSTGLGVLRARTGSRPRLTDDNEL Mflv_2569|M.gilvum_PYR-GCK RWLADGHFVLLGYQRCPVRDGEATVDTSSRLGVLRLRQDVLPQLTQKDEL Mvan_4069|M.vanbaalenii_PYR-1 RWLADGHFVLLGYQRCPVRDGEATVDPSSRLGVLRLREDVFPQLTNKDEL TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 RWLVDGNFTLLGYQRCTVENGHATVDESSRLGLLKRREEVLPQLTHNDQL MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 LVLAQARVGSYLRYGAYPYAIAVREYV------DGSVVEHRFVGLFSVAA Rv2476c|M.tuberculosis_H37Rv LVLAQARVGSYLRYGAYPYAIAVREYV------DGSVVEHRFVGLFSVAA MMAR_3829|M.marinum_M LVLAQARVGSYLRYGAYPYAIAIRESLG-----DGNIVEHRFVGLFTVAA MAV_1696|M.avium_104 LVLAQSVVGSYLRYGAYPYAIAVREYV------DGAVIEHRFVGLFTVAA MLBr_01249|M.leprae_Br4923 LVLAQAAVGNYLRYGAYPYAIAVREYDDG---GDGGIIEHRFVGLFTVAA Mflv_2569|M.gilvum_PYR-GCK LTLAQATIPSFLRYGAYPQIVVVREQSPERDAD---AIEHRFVGLFTVAA Mvan_4069|M.vanbaalenii_PYR-1 LTLAQATIPSFLRYGTYPQIVVVREQSGDADADDAAAIEHRFVGMFTVAA TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 LVLAQATTPTYLRYAIYPNIVVIRQDNG-----SGPAIEHRLVGVFTVAA MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 MNADVLEIPTISRRVREALAMAES-DPSHPGQLLLDVIQTVPRPELFTLS Rv2476c|M.tuberculosis_H37Rv MNADVLEIPTISRRVREALAMAES-DPSHPGQLLLDVIQTVPRPELFTLS MMAR_3829|M.marinum_M MNADVLEIPAISHRVRDALELAGN-DPSHPGQLLLDVIQTVPRPELFTLS MAV_1696|M.avium_104 MNADVLEIPTISRRVREALAMADS-DPIHPGQLLLDVIQTVPRSELFTLS MLBr_01249|M.leprae_Br4923 MNADVLEIPSISHRVRAALAMANS-DPIYPGQLLLDVIQTVPRSELFTLS Mflv_2569|M.gilvum_PYR-GCK MNANVLEIPLVSRRVNDALAMAHR-DPSHPGQLLLDIIQTIPRSELFALS Mvan_4069|M.vanbaalenii_PYR-1 MNANVLEIPLVSRRVNDALAMAHR-DPSHPGQLVLDIIQTIPRSELFALS TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 MNADVLAIPVVCDRVHQVLGRSDATQDSLAGHMLIEFMQNLPRAELFASS MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 AQRLLTMARAVVDLGSQRQALLFLRADRLQYFVSCLVYMPRDRYTTAVRM Rv2476c|M.tuberculosis_H37Rv AQRLLTMARAVVDLGSQRQALLFLRADRLQYFVSCLVYMPRDRYTTAVRM MMAR_3829|M.marinum_M SEQLLAMAKAVVDLGSQRRALLFLRVDRLQFFVSCLVYLPRDRYTTAVRL MAV_1696|M.avium_104 SERLLAMAKAVVDLGPQRNALLFLRADSLQYFVSCLVYLPRDRYTTAVRL MLBr_01249|M.leprae_Br4923 AERLFTMAKEVVDLGSGRRALLFLRADRLQYFVSCLVYVPRDRYTTGVRL Mflv_2569|M.gilvum_PYR-GCK ARGLLDMAMAVVDLGARRRTLLFMRADPLAHFVSCLVYLPRDRYTTVVRL Mvan_4069|M.vanbaalenii_PYR-1 ARGLLDMAMAVVDLGSRRRALLFMRADPLAHFVSCLVYLPRDRYTTAVRL TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 VDRLYDIVTASRNIGAHPGSLLFLRADELGNFVTALVYLPRDRYTTTVRL MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 QFEDILVREFGGTRLEFTARVSESPWALMHFMVRLPEVGVAGEGAAAPPV Rv2476c|M.tuberculosis_H37Rv QFEDILVREFGGTRLEFTARVSESPWALMHFMVRLPEVGVAGEGAAAPPV MMAR_3829|M.marinum_M QIEDILVREFGGTRLEFTARVSESPWALMHFMVRLPEDVATGS------I MAV_1696|M.avium_104 QIEDILVREFGGTRLEFTARVSESPWALMHFMVRLPTDDPAAK-----PV MLBr_01249|M.leprae_Br4923 QIEDILVREFGGTQVEFTARVSESPWALMHFMVRLSEGAATGS------V Mflv_2569|M.gilvum_PYR-GCK EMQDILVRELGGVSIDYAARVSESPWAVVHFTVRLPAGLRQHE------V Mvan_4069|M.vanbaalenii_PYR-1 EMQDILVRELGGVSIDYAARVSESPWAVVHFTVRMPEGSRPQD------I TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 AMQDTLVRELGGTGIDYTARVSESPWALVHFTVRLPENSPHNS------I MSMEG_6272|M.smegmatis_MC2_155 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 DVSEANRIRIQGLLTEAARTWADRLIG-AAAAG--SVGQADAMHYAAAFS Rv2476c|M.tuberculosis_H37Rv DVSEANRIRIQGLLTEAARTWADRLIGAAAAAG--SVGQADAMHYAAAFS MMAR_3829|M.marinum_M DVSEANRSRIQALLSEAARTWADRLIG-AASDA--SVRHADAEHYAAAFP MAV_1696|M.avium_104 DVSEDNRVRIQGLLSEAARTWTDRLVA-AAAEG--AVGHADAEYYADAFP MLBr_01249|M.leprae_Br4923 DVSEGNRIRIQAMLSEAARTWSDRLIAAAASFSEGSVSYAEAEHYAATFS Mflv_2569|M.gilvum_PYR-GCK DVSDDNEARIQDLLTEAARTWGDRLMGALPAGG--PVDHGTADHYASAFP Mvan_4069|M.vanbaalenii_PYR-1 DVSEPNESRIQDLLTEAARTWSDRLLGAVSAGG--EVDQATAEHYASAFS TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 DTSEANRVRIQGLLTQTTRTWSDRLVRAVRPDS--PIDRACAERYSVILP MSMEG_6272|M.smegmatis_MC2_155 --------------------------------------------MSTAFF Mb2503c|M.bovis_AF2122/97 EAYKQAVTPADAIGDIAVITELTDDSVKLVFSER---DEQGVAQLTWFLG Rv2476c|M.tuberculosis_H37Rv EAYKQAVTPADAIGDIAVITELTDDSVKLVFSER---DEQGVAQLTWFLG MMAR_3829|M.marinum_M EAYKQAVAPADAIDHIAIINELADDSVKLVFSDR---TADGVAQLTWFLG MAV_1696|M.avium_104 EVYKQAISPADAIGHIAIIKELQDNSVKLVFTD----GEDGSAQLTWFLG MLBr_01249|M.leprae_Br4923 ETYKQAVTPADAIDHIAIIKELADDSVKLVFFER---KADGFAQLTWFLG Mflv_2569|M.gilvum_PYR-GCK EVYKQANTPARALDDIAIIEELHDNTVKLVLADSDDTETSGVSDLNWYLG Mvan_4069|M.vanbaalenii_PYR-1 EVYKQAIDPVHALADIAVIEELQDNSVKLVLADSDDTAESGVSHLNWYLG TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 EVFKQNVPPAEAIADIARIEGLQEDSIDLAYDAD----ELGTGVLSMYLG MSMEG_6272|M.smegmatis_MC2_155 NGEELDALAGDEITVRLHHPVHPHEPLRFVLAAG---------------- Mb2503c|M.bovis_AF2122/97 GRTASLSQLLPMLQSMGVVVLEERPFSVTRPDGLPVWIYQFKISPHPTIP Rv2476c|M.tuberculosis_H37Rv GRTASLSQLLPMLQSMGVVVLEERPFSVTRPDGLPVWIYQFKISPHPTIP MMAR_3829|M.marinum_M GCTASLSQLLPMLQSMGVVVLEERPFTVTRPDGLPVWIYQFKISPHPTIP MAV_1696|M.avium_104 GRTASLSQLLPMLQSMGVVVLEERPFTVTRSDGLPVWIYQFRISPHPTIE MLBr_01249|M.leprae_Br4923 GRSASLSQLLPMLQSMGVVVLEERPFTVARTDGLPVWIYQFKISPHPTIP Mflv_2569|M.gilvum_PYR-GCK GQSASLSRLLPMLQSMGVVVLEERPFTVTRPDGLPVWIYQFKVSPHRGIP Mvan_4069|M.vanbaalenii_PYR-1 GRSASLSRLLPMLQSMGVVVLEERPFTVVRPDGLPVWIYQFKVSPHRGIP TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 GRSASLSQVLPVLHSMGVDVLEERPYHFTRPDGLAVSLYAFRIVVHPAIA MSMEG_6272|M.smegmatis_MC2_155 -QPVPLRRMLPALESMDLEVINEHTTSPTRDDGSVCHVYELVLDPGTAGA Mb2503c|M.bovis_AF2122/97 LAPTVAERAATAHRFAEAVTAIWHGRVEIDRFNELVMRAGLTWQQVVLLR Rv2476c|M.tuberculosis_H37Rv LAPTVAERAATAHRFAEAVTAIWHGRVEIDRFNELVMRAGLTWQQVVLLR MMAR_3829|M.marinum_M KATVPAERAAAAQRFADAVTAIWQGRIEIDRFNELVMRAGLTWQQVVLLR MAV_1696|M.avium_104 LASTPDERDAMAERFADAVTAIWQGRLEVDRFNELVMRAGLRWQQVVLLR MLBr_01249|M.leprae_Br4923 LASTANERELTAKRFSDAVTAIWQGRVEIDRFNELVMRARLTWQQVVLLR Mflv_2569|M.gilvum_PYR-GCK QAPPGPERDATAERFADTVTAIWHGNAEIDRFNELVLRAGLTWQQVAVLR Mvan_4069|M.vanbaalenii_PYR-1 EAPPGPQREATAERFADAVTAIWHGNAEIDRFNELVLRAELTWQQVAVLR TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 RTFDAEGTARRADLLTRAIDAVWHGRVETDRFNELVLRAGLTAGQITILR MSMEG_6272|M.smegmatis_MC2_155 QG-FARDWNRAQDQICDTFRAIWSDRIEADRLNALIPTAGLDWRQVAVLR Mb2503c|M.bovis_AF2122/97 AYAKYLRQAGFPYSQSYIESVLNEHPATVRSLVDLFEALFVP--VPSGSA Rv2476c|M.tuberculosis_H37Rv AYAKYLRQAGFPYSQSYIESVLNEHPATVRSLVDLFEALFVP--VPSGSA MMAR_3829|M.marinum_M AYSRYLRQAGFPYSQSYIESVLNEHPSTARSLVLLFEALFDP--RPAGSP MAV_1696|M.avium_104 AYAKYLRQANFPYSQSYIEAVLNEHPSTARSLVALFEALFDP--DPD-SS MLBr_01249|M.leprae_Br4923 AYAKYLRQAGFNYSQSYIESVLNEHPSTARSLVALFEALFDP--SPLSSS Mflv_2569|M.gilvum_PYR-GCK AYAKYLKQAGFPYSQSHIASVLNDNAGTARSLVELFEALYSPV-DGNPGG Mvan_4069|M.vanbaalenii_PYR-1 AYARYLKQAGFAYSQSHIESVLNDNAGTARSLIALFEALFRPV-EQGPG- TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_1561|M.abscessus_ATCC_1997 GYAKYLRQAGFPYSQAHIETVLADNSQTARDFVELFEARFDP-----EST MSMEG_6272|M.smegmatis_MC2_155 SYSRYLRQLPLPYGQGRIQQVLLDNPAATTAVVALFEARFARQSVSSGAV Mb2503c|M.bovis_AF2122/97 SNRDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTRQGS Rv2476c|M.tuberculosis_H37Rv SNRDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTRQGS MMAR_3829|M.marinum_M VSPDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVSREGS MAV_1696|M.avium_104 AGRDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTREGS MLBr_01249|M.leprae_Br4923 TNCDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTQKFS Mflv_2569|M.gilvum_PYR-GCK ANRDAQSAAAAVAADIDALVSLDTDRVLRAFASMIQATLRTNYFVTAADS Mvan_4069|M.vanbaalenii_PYR-1 ANRDAQAAAAAVAADIDALVSLDTDRVLRAFASMIQATLRTNYFITGQES TH_0917|M.thermoresistible__bu ------------------VVSLDTDRVLRAFASLIEATLRTNYFVSRDDS MAB_1561|M.abscessus_ATCC_1997 DDTIADAKAAQVLAEIDKVVSLDTDRVLRAFFGLIQATLRTNYFVKKEDS MSMEG_6272|M.smegmatis_MC2_155 RERDMAAADQRLEAEIDRVVHIDADRILRTYRSLVNATVRTNAFTPEALT :* :*:**:**:: .:::**:*** * : Mb2503c|M.bovis_AF2122/97 ARCRDVLALKLNAQLIDELPLPRPRYEIFVYSPRVEGVHLRFGPVARGGL Rv2476c|M.tuberculosis_H37Rv ARCRDVLALKLNAQLIDELPLPRPRYEIFVYSPRVEGVHLRFGPVARGGL MMAR_3829|M.marinum_M ARSRDVLSVKLDAQLIDELPLPRPKYEIFVYSPRVEGVHLRFGPVARGGL MAV_1696|M.avium_104 ARARNVLVIKLDAQLIDELPLPRPKYEIFVYSPRVEGVHLRFGPVARGGL MLBr_01249|M.leprae_Br4923 ARSKGVLVLKLDAQLINELPLPRPKFEIFVYSPRVEGVHLRFGAVARGGL Mflv_2569|M.gilvum_PYR-GCK ARARNVLSFKLNPELIDELPLPRPKFEIFVYSPRVEGVHLRFGFVARGGL Mvan_4069|M.vanbaalenii_PYR-1 ARARNVLSLKLNPQLIDELPLPRPKFEIFVYSPRVEGVHLRFGFVARGGL TH_0917|M.thermoresistible__bu DRARGVFSVKLRPALIKELPLPRPMFEIFVYSPRVEGVHLRFGHVARGGL MAB_1561|M.abscessus_ATCC_1997 ARAKGVLSFKLNPREIAELPEPRPRFEIFVYSPRVEGVHLRFGPVARGGL MSMEG_6272|M.smegmatis_MC2_155 PKAP-YLVHKFDASAIDELPQPRPLSEIFVYAPQFEGLHLRFGLVARGGL :. : *: . * *** *** *****:*:.**:***** ****** Mb2503c|M.bovis_AF2122/97 RWSDRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLPTGDPAA Rv2476c|M.tuberculosis_H37Rv RWSDRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLPTGDPAA MMAR_3829|M.marinum_M RWSDRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLSTGDAAT MAV_1696|M.avium_104 RWSDRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLPSGDGAA MLBr_01249|M.leprae_Br4923 RWSDRLDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVLKRPPLPTGDAAA Mflv_2569|M.gilvum_PYR-GCK RWSDRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKKPPAPTGDAAA Mvan_4069|M.vanbaalenii_PYR-1 RWSDRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKHPPAPTGDAAA TH_0917|M.thermoresistible__bu RWSDRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPAPTGDAAA MAB_1561|M.abscessus_ATCC_1997 RWSDRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKNPPAVTGDAAA MSMEG_6272|M.smegmatis_MC2_155 RWSDRHDDYRTEVLGLVKAQAVKNAMIVPAGAKGVFVVKPP--------- ***** :*:***:************:***.**** **:* * Mb2503c|M.bovis_AF2122/97 DRDATRAEGVACYQLFISGLLDVTDNVDHATASVNPPPEVVRRDGDDAYL Rv2476c|M.tuberculosis_H37Rv DRDATRAEGVACYQLFISGLLDVTDNVDHATASVNPPPEVVRRDGDDAYL MMAR_3829|M.marinum_M DREATRAEGVACYQLFISGLLDVTDNVDHTTGVVSPPPEVLRRDGDDAYL MAV_1696|M.avium_104 DRDATRAEGVACYQLFISGLLDVTDNVDHATGKVSPPPEVVRRDGDDAYL MLBr_01249|M.leprae_Br4923 DRDAMRAEGIACYQLFISGLLDITDNVDHATGKVNAPPQVVRRDSDDAYL Mflv_2569|M.gilvum_PYR-GCK DRDATREEGVACYRLFIAGLLDITDNVDKISGDVVTPAEVVRRDGDDAYL Mvan_4069|M.vanbaalenii_PYR-1 DRDATREEGVACYRLFIAGLLDITDNVDKVTGGIVAPADVVRRDGDDAYL TH_0917|M.thermoresistible__bu DREAARAEGIACYRLFVSGLLDITDNVDKTTGAVVPPAEVVRRDGDDAYL MAB_1561|M.abscessus_ATCC_1997 DRDAFRAEGVECYRRFISGLLDITDNRDRTTNAVVPPEGVRRRDGDDPYL MSMEG_6272|M.smegmatis_MC2_155 --SSSRTEGMRCYKQFVSALLDVVDN--AVSDEPPAPEGVVCHDGPDPYL .: * **: **: *::.***:.** : .* * :*. *.** Mb2503c|M.bovis_AF2122/97 VVAADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITARGA Rv2476c|M.tuberculosis_H37Rv VVAADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITARGA MMAR_3829|M.marinum_M VVAADKGTATFSDIANEVANSYGFWLGDAFASGGSVGYDHKAMGITAKGA MAV_1696|M.avium_104 VVAADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITARGA MLBr_01249|M.leprae_Br4923 VVAADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGA Mflv_2569|M.gilvum_PYR-GCK VVAADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGA Mvan_4069|M.vanbaalenii_PYR-1 VVAADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGA TH_0917|M.thermoresistible__bu VVAADKGTATFSDIANEVAQSYGFWLGDAFASGGSVGYDHKAMGITARGA MAB_1561|M.abscessus_ATCC_1997 VVAADKGTATFSDIANDVALSYGFWLGDAFASGGSVGYDHKAMGITARGA MSMEG_6272|M.smegmatis_MC2_155 VVAADKGTATFSDIANAVALDRGYWLGDAFASGGSAGYDHKAMGITARGA **************** ** . *:***********.***********:** Mb2503c|M.bovis_AF2122/97 WEAVKRHFREIGIDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFD Rv2476c|M.tuberculosis_H37Rv WEAVKRHFREIGIDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFD MMAR_3829|M.marinum_M WEAVKRHFREMGIDTQTEDFTVVGVGDMSGDVFGNGMLLSKHIRLIAAFD MAV_1696|M.avium_104 WEAVKRHFREMGVDTQTEDFTVVGIGDMSGDVFGNGMLLSKHIRLLAAFD MLBr_01249|M.leprae_Br4923 WEAVKRHFREMGVDTQNEDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFD Mflv_2569|M.gilvum_PYR-GCK WESVKRHFREMGIDTQSEDFTVVGVGDMSGDVFGNGMLLSEHIRLLAAFD Mvan_4069|M.vanbaalenii_PYR-1 WESVKRHFREMGVDTQSEDFTVVGVGDMSGDVFGNGMLLSKHIRLLAAFD TH_0917|M.thermoresistible__bu WESVKRHFREMGVDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLVAAFD MAB_1561|M.abscessus_ATCC_1997 WESVKRHFLEIGIDTQTQDFTVVGVGDMSGDVFGNGMLLSQHIKLVAAFD MSMEG_6272|M.smegmatis_MC2_155 WVSGDSHLQELGIDSATDEFRVVGIGDMSGDVFGNGMLLRRGIRLVAAFD * : . *: *:*:*: .::* ***:************** . *:*:**** Mb2503c|M.bovis_AF2122/97 HRHIFLDPNPDAAVSWAERRRMFELPRSSWGDYDRSLISEGGGVYSREQK Rv2476c|M.tuberculosis_H37Rv HRHIFLDPNPDAAVSWAERRRMFELPRSSWSDYDRSLISEGGGVYSREQK MMAR_3829|M.marinum_M HRHVFLDPNPDAAASWQERQRMFDLPRSSWDDYNKSLISEGGGVYSREQK MAV_1696|M.avium_104 HRHIFLDPNPDAAASWEERRRMFELPRSSWDDYDKSLISEGGGVYSREHK MLBr_01249|M.leprae_Br4923 HRHVFLDPDPDAAVSWAERQRMFDLPRSSWDDYNKSLISEGGGVYSREQK Mflv_2569|M.gilvum_PYR-GCK HRHIFIDPTPDAASSYAERRRLFDLPRSSWDDYDKSLISAGGGVYSREQK Mvan_4069|M.vanbaalenii_PYR-1 HRHIFIDPTPDAASSWEERKRLFELPRSSWEDYDTSLISPGGGVYSREQK TH_0917|M.thermoresistible__bu HRHIFLDPDPDPARSWEERKRLFELPRSSWDDYDTSVISRGGGVYSRQQK MAB_1561|M.abscessus_ATCC_1997 HRHIFLDPNPDPASSWAERKRMFALERSSWADYNSALISAGGGVYSKEQK MSMEG_6272|M.smegmatis_MC2_155 HRHIFVDPDPSTQAAYRERQRLFALARSSWDDYDRAVISAGGGVWPRTAK ***:*:** *.. :: **:*:* * **** **: ::** ****:.: * Mb2503c|M.bovis_AF2122/97 AIPLSAQVRAVLGIDGSVDGGAAEMAPPNLIRAILRAPVDLLFNGGIGTY Rv2476c|M.tuberculosis_H37Rv AIPLSAQVRAVLGIDGSVDGGAAEMAPPNLIRAILRAPVDLLFNGGIGTY MMAR_3829|M.marinum_M SIPVSDQVRNALGIGGDVT----EMTPPNLIRAILQAPVDLLFNGGIGTY MAV_1696|M.avium_104 SIPVSPQVRDALGLDGSGGGVVTEMTPPNLIKAILQAPVDLLFNGGIGTY MLBr_01249|M.leprae_Br4923 AIPTSPQVRTALGIDGEVT----EMAPPNLIRAILQAPVDLLFNGGIGTY Mflv_2569|M.gilvum_PYR-GCK SIPISDEARAALGIEGDAT----EMTPPALMKAILKAPADLLWNGGIGTY Mvan_4069|M.vanbaalenii_PYR-1 SIPVSAQARAALGLDDQVT----DLTPPALMKAILKAPADLLWNGGIGTY TH_0917|M.thermoresistible__bu SIPVSAEVRAALGLDGDVD----ALTPPAMIRAILRAPVDLLFNGGIGTY MAB_1561|M.abscessus_ATCC_1997 SIPISPEVRDVLGLDSDVV----EMTPPQLVRAILLAPVDLFFNGGIGTY MSMEG_6272|M.smegmatis_MC2_155 RIPVSEQMRATLGISGEIT----SVTPTELIRHILCAPVDLLFNGGIGTY ** * : * .**: .. ::*. ::: ** **.**::******* Mb2503c|M.bovis_AF2122/97 IKAESESDADVGDRANDPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLS Rv2476c|M.tuberculosis_H37Rv IKAESESDADVGDRANDPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLS MMAR_3829|M.marinum_M IKAESESDADVGDRANNPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLS MAV_1696|M.avium_104 IKAESESDADVGDRANDPVRVNGSSVRAKVIGEGGNLGVTALGRVEFDLS MLBr_01249|M.leprae_Br4923 IKAETESVADVGDRANDPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLS Mflv_2569|M.gilvum_PYR-GCK IKAETEADADVGDRANDPVRVNGNQVRAKVVGEGGNLGVTSLGRTEFDLC Mvan_4069|M.vanbaalenii_PYR-1 VKAETEADADVGDRANDAVRVNGNEVRAKVIGEGGNLGVTSRGRTEFDLC TH_0917|M.thermoresistible__bu IKAESESDADVGDRANDPVRVNGNQVRAKVIGEGGNLGVTPLGRVEYDLA MAB_1561|M.abscessus_ATCC_1997 VKAESESQADVGDKANDAVRVNGNQVRAKVIGEGGNLGLTSRGRIEFELN MSMEG_6272|M.smegmatis_MC2_155 IKASDEQHGDVGDKVNDNVRVDANQVRAKVIVEGGNLGVSPRGRIEFARN :**. * .****:.*: ***:...*****: ******::. ** *: Mb2503c|M.bovis_AF2122/97 GGRINTDALDNSAGVDCSDHEVNIKILIDSLVSAGTVKADERTQLLESMT Rv2476c|M.tuberculosis_H37Rv GGRINTDALDNSAGVDCSDHEVNIKILIDSLVSAGTVKADERTQLLESMT MMAR_3829|M.marinum_M GGRINTDALDNSAGVDCSDHEVNIKILIDSLVSAGKVRTDERKQLLESMT MAV_1696|M.avium_104 GGRINTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVKPQERKPLLESMT MLBr_01249|M.leprae_Br4923 GGRINTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVKVEERKHLLESMT Mflv_2569|M.gilvum_PYR-GCK GGRINTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVAEADRTELLLSMT Mvan_4069|M.vanbaalenii_PYR-1 GGRINTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVEESGRSALLSSMT TH_0917|M.thermoresistible__bu GGRINTDALDNSAGVDCSDHEVNIKILIDSLVAAGKIGADQRTDLLMSMT MAB_1561|M.abscessus_ATCC_1997 GGRVNTDALDNSAGVDCSDHEVNIKILIDSLVSAGKIEASERTALLESMT MSMEG_6272|M.smegmatis_MC2_155 GGYINTDAIDNAAGVDCSDHEVNLKILL-----AGRIRGTERNTLLADMT ** :****:**:***********:***: ** : *. ** .** Mb2503c|M.bovis_AF2122/97 DEVAQLVLADNEDQNDLMGTSRANAASLLPVHAMQIKYLVAERGVNRELE Rv2476c|M.tuberculosis_H37Rv DEVAQLVLADNEDQNDLMGTSRANAASLLPVHAMQIKYLVAERGVNRELE MMAR_3829|M.marinum_M DEVAQLVLTDNSDQNDLMGTSRANPVSLLPVHADQIRYLVAERGISRELE MAV_1696|M.avium_104 DEVAALVLTDNEDQNDLIGTSRANAPSLLPVHARQIQYLVDERGLNRELE MLBr_01249|M.leprae_Br4923 DEVARLVLTDNEDQNDLIGTSRANAANMLSVHAMQIKYLVDERGVNRELE Mflv_2569|M.gilvum_PYR-GCK DEVGRLVLADNESQNDLMGTSRANAASLLNVHARMIKDFVERRGLNRELE Mvan_4069|M.vanbaalenii_PYR-1 DEVGRLVLADNESQNDLMGTSRANAASLLNVHGRMIRSFVEERGLNRELE TH_0917|M.thermoresistible__bu DEVADMVLAHNARQNDLIGTSRANTAAMLTVHARLIDDLVENHGVNRELE MAB_1561|M.abscessus_ATCC_1997 DDVATLVLADNESQNNLMGTSRANAASLLSVHARQIAYLVNERGLDRELE MSMEG_6272|M.smegmatis_MC2_155 DEVAAHVLANNRAHNRLLRDARSNAAQMVSVHARMTTALERD-GLVRELE *:*. **:.* :* *: :*:*. :: **. : *: **** Mb2503c|M.bovis_AF2122/97 ALPSEKEIARRSEAGIGLTSPELATLMAHVKLGLKEEVLATELPDQDVFA Rv2476c|M.tuberculosis_H37Rv ALPSEKEIARRSEAGIGLTSPELATLMAHVKLGLKEEVLATELPDQDVFA MMAR_3829|M.marinum_M ALPSEKEIARRSEAGIGLTSPELATLMAHVKLALKETMLTTELPDQDVFA MAV_1696|M.avium_104 ALPSEKEIQRRAEAGIGLTSPELCTLMAHVKLDLKEQMLQTELTEQDVFA MLBr_01249|M.leprae_Br4923 ALPSEKEIQRRSEAGIGLTSPELSTLMAHVKLALKEQMLATELPDQDVFV Mflv_2569|M.gilvum_PYR-GCK ALPSEKEILRRTEAGLGLTSPELATLMAHVKLALKDDLLAGELPDQEVFA Mvan_4069|M.vanbaalenii_PYR-1 ALPSEKEIRRREEAGIGLTSPELATLMAHVKLALKDDLLAGDLPDQEVFA TH_0917|M.thermoresistible__bu ALPSDKEIARRSDTGVGLTSPELATVMAHVKLTLKDALLASELPDQEVFA MAB_1561|M.abscessus_ATCC_1997 ALPSEKEIDRRAALGIGLTSPELATLMAHVKLGLKDDLLASDAPDQEVTL MSMEG_6272|M.smegmatis_MC2_155 HLPSAEEFAAMASAGEGLTRPQLATLMAHTKLGLKADLLAADDFDDPYFT *** :*: * *** *:*.*:***.** ** :* : :: Mb2503c|M.bovis_AF2122/97 SRLPRYFPTALRERFTPEIRSHQLRREIVTTMLINDLVDTAGITYAFRIA Rv2476c|M.tuberculosis_H37Rv SRLPRYFPTALRERFTPEIRSHQLRREIVTTMLINDLVDTAGITYAFRIA MMAR_3829|M.marinum_M SRLPSYFPKPLRERFAPEIRSHQLRREIVTTMVINDLVDTAGITYAFRIT MAV_1696|M.avium_104 SRLPLYFPTPLRHRFTPEIRAHQLRREIVATMLINELVDAAGISYAFRIV MLBr_01249|M.leprae_Br4923 SRLPRYFPKPLRERFTPEIRSHQLRREIVTTMLINDLVDTAGISYAFRIA Mflv_2569|M.gilvum_PYR-GCK SRLPSYFPTTLRERFGPDIRSHQLRREIVTTMLVNDVVDTAGISYAYRVA Mvan_4069|M.vanbaalenii_PYR-1 SRLPSYFPATLRDQFSPEIRAHQLRREIVTTMLVNDVVDTAGISYAYRVT TH_0917|M.thermoresistible__bu ARLPSYFPRPLRD-FTAEIRGHQLRREIVSTMLVNDLVDTAGLTYAFRVC MAB_1561|M.abscessus_ATCC_1997 RRMVHYFPDVLRERFDAEIRQHPLRKEIYATMLVNSVVDCGGITYVYRLF MSMEG_6272|M.smegmatis_MC2_155 AALHRYFPATLRRRLGDRLTEHPLRREIVATAVVNHVLATSGLTYAFRLV : *** ** : : * **:** :* ::* :: .*::*.:*: Mb2503c|M.bovis_AF2122/97 EDVGVTPIDAVRTYVATDAIFGVGHIWRRIRAANLP----IALSDRLTLD Rv2476c|M.tuberculosis_H37Rv EDVGVTPIDAVRTYVATDAIFGVGHIWRRIRAANLP----IALSDRLTLD MMAR_3829|M.marinum_M EDVGVSPIDAVRTYMATDAIFGVSHIWRRIRAEELP----VALSDRLTLD MAV_1696|M.avium_104 EDVGVSAVDAVRTYVATDAIFGVGEIWRRIRAANLP----VALSDRLTLD MLBr_01249|M.leprae_Br4923 EDIGVGPIDAIRTYVATDAIFGVGDVLRRIRAANLS----VVLSDRMTLD Mflv_2569|M.gilvum_PYR-GCK EDVGVAPIDAVRSFAAGDAIFGFGRVWRQIREAGANGVS-VAVTDRMTLD Mvan_4069|M.vanbaalenii_PYR-1 EDVGVAPVDAVRSFVAADAIFGVGRVWRQIREAGANGVP-VAVTDRMTLD TH_0917|M.thermoresistible__bu EDAGVEPVDAVRSFVAVDAIFRVGEIWHAIRTAGAEGVLPVAVSDRMTLD MAB_1561|M.abscessus_ATCC_1997 EDAGTGSVDGLKTYVAVEAIFGLRSLWDRIRHADVP----VAVSDRLTLD MSMEG_6272|M.smegmatis_MC2_155 EETDAGTSEIVRAHAVASEVFELDALWHDIHAAGLS----PQLTDSLIIE *: .. . : :::. . . :* . : *: ::* : :: Mb2503c|M.bovis_AF2122/97 TRRLIDRAGRWLLNYRPQPLAVGAEINRFAAMVKALTPRMSEWLRGDDKA Rv2476c|M.tuberculosis_H37Rv TRRLIDRAGRWLLNYRPQPLAVGAEINRFAAMVKALTPRMSEWLRGDDKA MMAR_3829|M.marinum_M TRRLIDRASRWLLNYRPQPLAVGAEINRFAAKVKALTPRMSEWLRGDDKA MAV_1696|M.avium_104 TRRLIDRAGRWLLNYRPQPLAVGAEINRFAAKVKALTPRMSEWLRGDDKA MLBr_01249|M.leprae_Br4923 TRRLIDRAGRWLLNYRPQPLAVGAEINRFAAKVKALTPRMSEWLRGDDQA Mflv_2569|M.gilvum_PYR-GCK LRRLIDRATRWLLNYRPLPLAVGAEINRFADKVAALTPSMPDWLRGDDKA Mvan_4069|M.vanbaalenii_PYR-1 LRRLIDRAARWLLNYRPQPLAVGAEINRFADKVAALTPRMPDWLRGDDKA TH_0917|M.thermoresistible__bu LRRLIDRAARWLLNFRPQPLAVGAEINRFAAKVAALTPRMSEWLCGADAD MAB_1561|M.abscessus_ATCC_1997 MRRLLDRASRWLISYRPQPLAVGAEINRFAEGIAELSPKLTTWLRGHDLE MSMEG_6272|M.smegmatis_MC2_155 GRRLLDRASRWFLLNRPQPLSIAAEAARFQA-VAMLRGKLSEMLRGDELL ***:*** **:: ** **::.** ** : * :. * * : Mb2503c|M.bovis_AF2122/97 IVEKTAAEFASQGVPEDLAYRVSTGLYRYSLLDIIDIADIADIDAAEVAD Rv2476c|M.tuberculosis_H37Rv IVEKTAAEFASQGVPEDLAYRVSTGLYRYSLLDIIDIADIADIDAAEVAD MMAR_3829|M.marinum_M IVEKTSEEFIAQGAPEDLAYRVAVGLYRYSLLDIIDIADIADIDAAEVAD MAV_1696|M.avium_104 IVEKEAAEFESQGAPRDLAYLVAAGLYRFSLLDIIDIGDINDIDAAEVAD MLBr_01249|M.leprae_Br4923 IVEQQATEFVSQGAPEDLAYRVAVGLYRYSLLDIIDIADITELDPAEVAD Mflv_2569|M.gilvum_PYR-GCK IVEKEAGEFSAHGVAEDVAYTVATGLYQFSLLDVIDIADIIDRDPAEVAD Mvan_4069|M.vanbaalenii_PYR-1 IVAKEAAEFSSQGVPDDVAYMVASGLYQFSLLDVIDIADIVDRDPAEVAD TH_0917|M.thermoresistible__bu IVARRTADFVEHGASRQLAYLVSSALYQFSLLDIIDIADILDREPAEVAE MAB_1561|M.abscessus_ATCC_1997 IVTKQTEDLVALGVPFDLASDVASCLYGFSLLDIIDIADIADRDGAEVAD MSMEG_6272|M.smegmatis_MC2_155 TVTRLHDEYVAQGVPADIARRLSEALYSYSLLDIIDIAHAHSEDATRLAH * : : *.. ::* :: ** :****:***.. . : :.:*. Mb2503c|M.bovis_AF2122/97 TYFALMDRLGTDGLLTAVSQLPRHDRWHSLARLAIRDDIYGALRSLCFDV Rv2476c|M.tuberculosis_H37Rv TYFALMDRLGTDGLLTAVSQLPRHDRWHSLARLAIRDDIYGALRSLCFDV MMAR_3829|M.marinum_M TYFALVDRLGADGLLTAVSELPRKDRWHSLARLAIRDDIYGALRSLCFDV MAV_1696|M.avium_104 TYFALMDRLGTDGLLTAVSELPRNDRWHSLARLAICDDIYASLRSLCFDV MLBr_01249|M.leprae_Br4923 TYFSLMDRLGTDGLLTAVSKLPQNDRWHSLARLAIRDDIYASLRSLCFDV Mflv_2569|M.gilvum_PYR-GCK AYFALMDHLGTDGLLTAVSRLSRNDRWHSLARLAIRDDIYGSLRALCFDV Mvan_4069|M.vanbaalenii_PYR-1 AYFALMDHLGTDGLLTAVSRLSRYDRWHSLARLAIRDDIYGSLRALCFDV TH_0917|M.thermoresistible__bu TYFALMGHLNADALLTAVSELPRSDRWHSLARLAIRDDIYGSLRLLTVDV MAB_1561|M.abscessus_ATCC_1997 LYFTLMDDLRVDDLLTAVSQLERNDRWHSLARLAIRDDIYSSLRALTMDV MSMEG_6272|M.smegmatis_MC2_155 IYFELSAHLGVDGLLYAVSSLPRNGRWNALARLALREDLYRSLRDLARDV ** * * .* ** *** * : .**::*****: :*:* :** * ** Mb2503c|M.bovis_AF2122/97 LAVGEPGESSEQKIAEWEHLSASRVARARRTLDDIRASGQKDLATLSVAA Rv2476c|M.tuberculosis_H37Rv LAVGEPGESSEQKIAEWEHLSASRVARARRTLDDIRASGQKDLATLSVAA MMAR_3829|M.marinum_M IAVGEPDESSEQKILEWEQLSASRVDRARRTLNEIRDSGQKDLATLSVAA MAV_1696|M.avium_104 LAVGEPDESGEEKIAEWEHLSASRVERARRTLIEIQESGAKDLATLSVAA MLBr_01249|M.leprae_Br4923 LAVGEPDESGEEKIAEWEHISASRVERARLMLAEIHASGEKDLATLSVAA Mflv_2569|M.gilvum_PYR-GCK LAVGEPDENGVEKIAEWEMTNRSRISRARRTLTELYESGEHDLATLSVAA Mvan_4069|M.vanbaalenii_PYR-1 LAVGEPDEDGVEKIAEWETTNSSRVSRARRTLAELYESGEHDLATLSVAA TH_0917|M.thermoresistible__bu LAVGEPDESGEEKIAEWESTNSSRLRRARRTLDEIYQDDIRDLATLSVAA MAB_1561|M.abscessus_ATCC_1997 LSVGEPDETGEQKIAEWEFTNASRLERARGTLAEIFAAGEPDLATLSVAA MSMEG_6272|M.smegmatis_MC2_155 YRMVGPHTDNVDVIAEFEAYNRPRIERARRTLREVLATENPDLAMLSVAT : * . : * *:* . .*: *** * :: *** ****: Mb2503c|M.bovis_AF2122/97 RQIRRMTRTSGRGISG Rv2476c|M.tuberculosis_H37Rv RQIRRMTRTSGRGISG MMAR_3829|M.marinum_M RQVRRMTRTSGRGISG MAV_1696|M.avium_104 RQIRRMTRTSGRGSSS MLBr_01249|M.leprae_Br4923 RQIRRMTRTSGRGSSG Mflv_2569|M.gilvum_PYR-GCK RQIRSMTRTSGTGSSG Mvan_4069|M.vanbaalenii_PYR-1 RQIRSMTRTSGTGSSG TH_0917|M.thermoresistible__bu RQIRAMTRTSGTGSSA MAB_1561|M.abscessus_ATCC_1997 RQIRGMIRSSITGPA- MSMEG_6272|M.smegmatis_MC2_155 AQVRRLTTAGG----- *:* : :.