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TDVSAQPPDPDDNRDVLTDRQGHPIFDNQNQRSVGARGPATMENYHFLEKMSHFDRERIPERVVHARGAV AFGYFEATGRWGDEPIERYTRAKLFNTPGKRTDLAIRLSTVIGGRDSSEVARDPRGFAVKFYTEDGNWDL VGNNLAVFFIRDAIKFPDVIHALKPDPVTHHQEPARIFDFMSQTPECMHMLVNLFSPRGIPANYRTMQGF GVNTYRWVNAEGQTHLVKYHWMPKAGVKSLTEEDAAAIQATELGSATKDLYEAIERGDYPEWELLVQIMS DDEHPELDWDPLDDTKVWPENDFPPKLVGRMVLNRNVDNFFNDNEQLAMGTGVLVDGMDFSEDKMLIGRS FSYSDTQRYRVGPNYLQLPVNRPKNAKVATNQQGGPMQYGVDNNGANPHVNYEPSITGGLREAQAPTADE YGPEFIGRITRKRIPRTNDYEQAGQRYQLMDQWEKDDLVKNFVTNISEATREVQERMVWHFLMCDDELGL RVGEGLGITVDDVRDLEPLKSQTLSDAEEKRRQNLGKNGPRDVTGLTMTHCVPNERVVMAGK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6232 | katA | - | 100% (553) | catalase KatA |
| M. smegmatis MC2 155 | MSMEG_3486 | katA | 3e-89 | 39.34% (483) | catalase KatA |
| M. smegmatis MC2 155 | MSMEG_3708 | - | 1e-08 | 26.62% (308) | catalase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3446 | - | 9e-92 | 41.05% (514) | catalase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2530c | - | 1e-100 | 40.15% (523) | catalase CatB |
| M. marinum M | MMAR_5217 | katE | 2e-90 | 39.26% (484) | catalase KatE |
| M. avium 104 | MAV_4069 | katE | 1e-109 | 42.75% (538) | catalase HPII |
| M. thermoresistible (build 8) | TH_4479 | - | 4e-91 | 39.15% (493) | PUTATIVE catalase KatE |
| M. ulcerans Agy99 | MUL_4291 | katE | 1e-90 | 39.26% (484) | catalase KatE |
| M. vanbaalenii PYR-1 | Mvan_3201 | - | 2e-95 | 43.11% (508) | catalase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5217|M.marinum_M -------------------------------------MAER-YTTTDAGS
MUL_4291|M.ulcerans_Agy99 -------------------------------------MAER-YTTTDAGN
TH_4479|M.thermoresistible__bu -----------------------------------MTMTTRPFTTTDGGA
MSMEG_6232|M.smegmatis_MC2_155 --------------------------MTDVSAQPPDPDDNRDVLTDRQGH
Mflv_3446|M.gilvum_PYR-GCK ------MPAARKRDQSAPAAVSPTGAAKDTQEQQDPRSQSGRHLTTAQGL
Mvan_3201|M.vanbaalenii_PYR-1 ------MPAPRKRDQSAPTRVSPTGASKSTDEQPDPRAQSGRFLTTAQGV
MAB_2530c|M.abscessus_ATCC_199 -----------------MDRTS---NPKQEQLDTSRVDRASGYLTTQQGV
MAV_4069|M.avium_104 MVLPHGRKGRKERQHMATDHTSDAPDPKQRDLESARFRRDTGYLTTQQGV
* *
MMAR_5217|M.marinum_M PAPSDDQSLTIGPDGPILLQDHYLIEQMAMFNRERIPERQPHAKGGGAHG
MUL_4291|M.ulcerans_Agy99 PAPSDDQSLTIGPDGPILLQDHYLIEQMAMFNRERIPERQPHAKGGGAHG
TH_4479|M.thermoresistible__bu PAPSDERSLTVGPDGPILLQDHYLIEQMANFNRERIPERQPHAKGAGAFG
MSMEG_6232|M.smegmatis_MC2_155 PIFDNQNQRSVGARGPATMENYHFLEKMSHFDRERIPERVVHARGAVAFG
Mflv_3446|M.gilvum_PYR-GCK RLPDTDHSLKAGSRGPTLMEDFHLREKITHFDHERIPERVVHARGAAAHG
Mvan_3201|M.vanbaalenii_PYR-1 RIPDTDHSLKAGSRGPTLMEDFHLREKITHFDHERIPERVVHARGAAAHG
MAB_2530c|M.abscessus_ATCC_199 RVDHTDDALTAGVRGPTLLEDFHAREIVTHFDHERIPERVVHARGAGAYG
MAV_4069|M.avium_104 RVDHTDDALTVGERGPTLLEDFHAREKITHFDHERIPERVVHARGAGAYG
: . * ** :::.: * :: *::****** **:*. *.*
MMAR_5217|M.marinum_M HFEVT-----HDVSKYTRAAVF-APGAKTDTLIRFSTVAGERGSPDTWRD
MUL_4291|M.ulcerans_Agy99 HFEVT-----HDVSKYTRAAVF-APGAKTDTLIRFSTVAGERGSPDTWRD
TH_4479|M.thermoresistible__bu IFEVT-----NDVSRYTRAAVF-QPGVKTDMLARFSTVAGERGSPDTWRD
MSMEG_6232|M.smegmatis_MC2_155 YFEATGRWGDEPIERYTRAKLFNTPGKRTDLAIRLSTVIGGRDSSEVARD
Mflv_3446|M.gilvum_PYR-GCK VFEAYGN-----AASVTKAAFLSKKGAKTDVFCRFSTVLGSRGSADTVRD
Mvan_3201|M.vanbaalenii_PYR-1 VFEAYGN-----AASITKAAFLASKGKRTDVFCRFSTVLGSRGSADTVRD
MAB_2530c|M.abscessus_ATCC_199 YFEPYDAW----LSDFTAAKFLTTPGLRTPVFVRFSTVAGSRGSADTVRD
MAV_4069|M.avium_104 YFEPYDDR----LAQYTAAKFLTSPGTRTPVFVRFSTVAGSRGSADTVRD
** * * .: * :* *:*** * *.*.:. **
MMAR_5217|M.marinum_M PRGFALKFYTSEGNFDMVGNNTPVFFMRDPLKFQHFIRSQKRMQ----AT
MUL_4291|M.ulcerans_Agy99 PRGFALKFYTSEGNFDMVGNNTPVFFMRDPLKFQHFIRSQKRMQ----AT
TH_4479|M.thermoresistible__bu PRGFALKFYTSEGNFDLVGNNTPIFFMRDPMKFQHFIRSQKRLA----RN
MSMEG_6232|M.smegmatis_MC2_155 PRGFAVKFYTEDGNWDLVGNNLAVFFIRDAIKFPDVIHALKPDP----VT
Mflv_3446|M.gilvum_PYR-GCK TRGFAVKFYTDEGVFDLVGNNMPVFFIQDGIKFPDVVHAAKPHPDREIPQ
Mvan_3201|M.vanbaalenii_PYR-1 TRGFAVKFYTEEGTFDLVGNNIPVFFIQDGIKFPDVIHAGKPHPDREIPQ
MAB_2530c|M.abscessus_ATCC_199 VRGFATKFYTQQGNYDLVGNNFPVFFIQDGIKFPDFVHAVKPEPDNEIPQ
MAV_4069|M.avium_104 VRGFATKFYTEQGNYDLVGNNFPVFFIQDGIKFPDFVHAVKPEPHNEIPQ
**** ****.:* :*:**** .:**::* :** ..::: *
MMAR_5217|M.marinum_M NLRDHNMQWDFWSLSPESAHQVTWLMGDRGIPKSWRHMNGYSSHTYSWIN
MUL_4291|M.ulcerans_Agy99 NLRDHNMQWDFWSLSPESAHQVTWLMGDRGIPKSWRQMNGYSSHTYSWIN
TH_4479|M.thermoresistible__bu NLRDHNMQWDFWTLSPESAHQVTWLMGDRGIPKTWRHMNGYGSHTYSWIN
MSMEG_6232|M.smegmatis_MC2_155 HHQEPARIFDFMSQTPECMHMLVNLFSPRGIPANYRTMQGFGVNTYRWVN
Mflv_3446|M.gilvum_PYR-GCK AQSAHDTFWDFVSLHTEATHHVFWNMSDRGIPRSYRTMEGFGVHTFRLVN
Mvan_3201|M.vanbaalenii_PYR-1 AQSAHDTFWDFVSLHTEATHHVLWNMSDRGIPRSYRTMEGFGVHTFRLVN
MAB_2530c|M.abscessus_ATCC_199 AASAHDTLWDFVAEQPETLHAIMWLMSDRALPRSYRMMQGFGVHTFRLVN
MAV_4069|M.avium_104 AQSAHDTLWDFVSLQPETLHAIMWLMSDRALPRSYRMMQGFGVHTFRLVN
:** : .* * : :. *.:* .:* *:*:. :*: :*
MMAR_5217|M.marinum_M AADEIFWVKYHFITDQGIDFLTQEDADRLAGTDGDYHQRDLYEAIERGDF
MUL_4291|M.ulcerans_Agy99 AADEIFWVKYHFITDQGIDFLTQEDADRLAGTDGDYHQRDLYEAIERGDF
TH_4479|M.thermoresistible__bu ADGEIFWVKYHFKTDQGIEFLTQEEADRLAGEDADYHTRDLYEAIEGGQY
MSMEG_6232|M.smegmatis_MC2_155 AEGQTHLVKYHWMPKAGVKSLTEEDAAAIQATELGSATKDLYEAIERGDY
Mflv_3446|M.gilvum_PYR-GCK RKGETSLVKFHWKPVAGVHSLVWEEAQLAAGFDPDFHRRDMADGIEAGAP
Mvan_3201|M.vanbaalenii_PYR-1 AKGETSLVKFHWKPVAGVHSLVWEEAQLAAGFDPDFHRRDMADGIEAGAP
MAB_2530c|M.abscessus_ATCC_199 DAGEGVFVKFHWKPLLGVHSLLWDECQQIAGKDPDFNRRDLWDAIESGQF
MAV_4069|M.avium_104 ARGEGTFVKFHWKPRLGVHSLIWDECQKIAGKDPDYNRRDLWEAIESGQY
.: **:*: . *:. * ::. . : . :*: :.** *
MMAR_5217|M.marinum_M PSWTLKMQIMGFEEAKSYR-FNPFDLTKVWPHSDYPLIDVGKLTLDRNVT
MUL_4291|M.ulcerans_Agy99 PSWTLKMQIMGFEEAKSYR-FNPFDLTKVWPHSDYPLIDVGKLTLDRNVT
TH_4479|M.thermoresistible__bu PSWTLKVQIMPFEEAKTYR-FNPFDLTKVWPHGDYPLIDVGTMTLNRNVE
MSMEG_6232|M.smegmatis_MC2_155 PEWELLVQIMSDDEHPELD-WDPLDDTKVWPENDFPPKLVGRMVLNRNVD
Mflv_3446|M.gilvum_PYR-GCK LEYELGVQVMPDDGTETFEGIDLLDPTKIVPEELVPVQLIGKLTLDRNPT
Mvan_3201|M.vanbaalenii_PYR-1 LEYELGVQVMPDDGTETYAGIDLLDPTKIVPEELVPVQLIGKLTLNRNPT
MAB_2530c|M.abscessus_ATCC_199 PEWELGVQLVPESDEFKFP-FDLLDSTKIIPEEQVPVQPVGRMVLDRNPD
MAV_4069|M.avium_104 PEWELGVQLVAEDDEFSFD-FDLLDATKIIPEEQVPVLPVGKMVLNRNPD
.: * :*:: . : :* **: *. * :* :.*:**
MMAR_5217|M.marinum_M DYHTEIEQAAFEPNNIVPGTGLSPDKMLLARGFSYSDAHRARLG-TNYRQ
MUL_4291|M.ulcerans_Agy99 DYHTEIEQAAFEPNNIVPGTGLSPDKMLLARGFSYSDAHRARLG-TNYRQ
TH_4479|M.thermoresistible__bu DYHTEMEQAAFEPNNLVPGTGLSPDKMLLARGFSYADAHRARLG-VNYKQ
MSMEG_6232|M.smegmatis_MC2_155 NFFNDNEQLAMGTGVLVDGMDFSEDKMLIGRSFSYSDTQRYRVG-PNYLQ
Mflv_3446|M.gilvum_PYR-GCK NYFAETEQVAFHLGNLVPGIEVTNDPLLQARLFSYLDTQLTRLGGPNFNQ
Mvan_3201|M.vanbaalenii_PYR-1 NYFAETEQVAFHTGNLVPGIEVTNDPLMQARLFSYLDTQLTRLGGPNFTQ
MAB_2530c|M.abscessus_ATCC_199 NFFAETEQVAFHTANVVPGIDFTNDPLLQFRNFSYLDTQLIRLGGPNFAQ
MAV_4069|M.avium_104 NFFAETEQVAFHTANVVPGIDFTNDPLLQFRNFSYLDTQLIRLGGPNFAQ
::. : ** *: :* * .: * :: * *** *:: *:* *: *
MMAR_5217|M.marinum_M IPVNSPI-VQVNSYSKDGAMRVRNASDPVYAPNSYGGPQAD---PARAAE
MUL_4291|M.ulcerans_Agy99 IPVNSPI-VQVNSYSKDGAMRVRNASDPVYAPNSYGGPQAD---PARAAE
TH_4479|M.thermoresistible__bu IPVNSPR-VEVHSYSKDGAMRIQNVKDPVYAPNSYGGPVAD---ESRAAE
MSMEG_6232|M.smegmatis_MC2_155 LPVNRPKNAKVATNQQGGPMQYGVDNNGANPHVNYEPSITGGLREAQAPT
Mflv_3446|M.gilvum_PYR-GCK LPINRPR-CPVNDMLRDGMHQTAIHTGQAPYLPNSIDGGEPLVADADEGG
Mvan_3201|M.vanbaalenii_PYR-1 LPINRPR-CPVNDMLRDGMHQTAIHTGQAPYRPNSIDGGEPLVADADEGG
MAB_2530c|M.abscessus_ATCC_199 LPINRPI-AEVHNNQRDGFAQHDIPQGKSSYFKNTLGGGCPALAHED--V
MAV_4069|M.avium_104 LPVNRPV-AQVRTNQHDGYGQHAIPQGRSSYFKNSIGGGCPALADED--V
:*:* * * :.* : . .
MMAR_5217|M.marinum_M VRWHADGQMMRAAYTPHPEDDDWGQAGTMVREVLDDSARDRLVSNIIGHV
MUL_4291|M.ulcerans_Agy99 VRWHADGQMMRAAYTPHPEDDDWGQAGTMVREVLDDSARDRLASNIIGHI
TH_4479|M.thermoresistible__bu VRWMSDGEMVRSAYTLHAEDDDWGQAGTLVREVLDDAARERLANNIIGHV
MSMEG_6232|M.smegmatis_MC2_155 ADEYGPEFIGRITRKRIPRTNDYEQAG-QRYQLMDQWEKDDLVKNFVTNI
Mflv_3446|M.gilvum_PYR-GCK YVQTPRPVEGRVGRVAPASFDDHFTQPAMFYRSLTPIEQDHIVEAFTFEL
Mvan_3201|M.vanbaalenii_PYR-1 YVQSARPVEGRVARVAPTSFDDHFTQAAMFYRSLTPIEQAHIVEAFTFEL
MAB_2530c|M.abscessus_ATCC_199 FRHYTQRVDGHKIRQRAESFKDFYSQPRMFWNSMSAVEAQHIVSAFSFEL
MAV_4069|M.avium_104 FRHYTQRVDGQTMRKRAEAFQNHYGQARMFFKSMSPVEAEHIVAAFAFEL
: .: . : :. : .:
MMAR_5217|M.marinum_M CKGVKEP-VLSRVFEYWRNVDPDLGKAVEEGVRANSS-------------
MUL_4291|M.ulcerans_Agy99 CKGVKEP-VLSRVFEYWRNVDPDLGKAVEEGVRANSS-------------
TH_4479|M.thermoresistible__bu SNGVKEP-VLSRVFEYWRNVDADLGKKVEEGVRARLNHTN------GV--
MSMEG_6232|M.smegmatis_MC2_155 SEATRE--VQERMVWHFLMCDDELGLRVGEGLGITVDDVR------DLEP
Mflv_3446|M.gilvum_PYR-GCK GKCYEQA-IKERQLEVLANVDADLCAKVAAGLGLPAPKGNPPKD-VTLSP
Mvan_3201|M.vanbaalenii_PYR-1 GKCYEQA-VKERQLEVLADVDAELCEQVAQGLGLPAPKGKPPAE-VTLSP
MAB_2530c|M.abscessus_ATCC_199 GKVSAEAGIRERVVAQLNLVEHDLASQVALQLGLPAPAPQSADEALPPSP
MAV_4069|M.avium_104 GKVEMPE-IRSAVVAQLARVDDQLAAQVAAKLGLPEPPEEQVDESAPVSP
: : . . : :* * :
MMAR_5217|M.marinum_M --------------------------------------------------
MUL_4291|M.ulcerans_Agy99 --------------------------------------------------
TH_4479|M.thermoresistible__bu --------------------------------------------------
MSMEG_6232|M.smegmatis_MC2_155 LKSQTLS--DAEEKRRQNLGKNGPRDVTGLTMTHCVPNERVVMAGK----
Mflv_3446|M.gilvum_PYR-GCK ALSQVVTTPGPVAGRKVAIIADADSDLAGVSKLIKAMDKAGVVPMVTAPV
Mvan_3201|M.vanbaalenii_PYR-1 ALSQVVTTPGPVKGRKVAIIADDDSDLAGVAKLVKALDKAGVIPAIVAPA
MAB_2530c|M.abscessus_ATCC_199 ALSQLSTTRDSIATRRIAVLAADGVDIHGVELLRAALEESDAIVEILAPT
MAV_4069|M.avium_104 ALSQVTDGGDTIASRRIAVLAADGVDVVGTQRFTELMEQRGAVVEVLAPV
MMAR_5217|M.marinum_M --------------------------------------------------
MUL_4291|M.ulcerans_Agy99 --------------------------------------------------
TH_4479|M.thermoresistible__bu --------------------------------------------------
MSMEG_6232|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3446|M.gilvum_PYR-GCK GGTLKSGRR--SVIVERTFDTARSIEFDAVVVADGALQRHDIK----AVV
Mvan_3201|M.vanbaalenii_PYR-1 GGILKSGRR--TLTVDRTFDTARSIEFDAVVVAGGALERLDIK----MVV
MAB_2530c|M.abscessus_ATCC_199 GGGTLTGESGGELRVDRAMTTMASVLYDAVVVPSGAESAWRLARNGFAVH
MAV_4069|M.avium_104 AGGTLAGGSGGELRVDRSFTTMASVLYDAVVVACGPRSVSTLSDDGYAVH
MMAR_5217|M.marinum_M --------------------------------------------------
MUL_4291|M.ulcerans_Agy99 --------------------------------------------------
TH_4479|M.thermoresistible__bu --------------------------------------------------
MSMEG_6232|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3446|M.gilvum_PYR-GCK LLHEMLRHCKPLGAWGNGSAALEAAGISLSDPGVVTSGDVSTAFGTELLA
Mvan_3201|M.vanbaalenii_PYR-1 LLHEMLRHCKPLGAWGDARNALQRVDIDLQDPGVVTDDDASSSFGAELLA
MAB_2530c|M.abscessus_ATCC_199 FVSEAYKHLKPVAAYGSGLDLLRAASVVET-LATTTEIVVDDGVVTTTAE
MAV_4069|M.avium_104 FVTEAYKHLKPIGAYGAGVDLLRKAGIGNR-LAEDTDVLNDQAVVTTKAA
MMAR_5217|M.marinum_M -----------------------------------
MUL_4291|M.ulcerans_Agy99 -----------------------------------
TH_4479|M.thermoresistible__bu -----------------------------------
MSMEG_6232|M.smegmatis_MC2_155 -----------------------------------
Mflv_3446|M.gilvum_PYR-GCK ALGLHRVWERADAVMASAVPPVSASVKTTKRSRKG
Mvan_3201|M.vanbaalenii_PYR-1 ALGLHRVWDRADAVMSSAVAPVRPAAPTTKRTRRR
MAB_2530c|M.abscessus_ATCC_199 ANALP---AEFVAAFVTAISRHRAWERETEMVPA-
MAV_4069|M.avium_104 ADELP---ERFAEEFAAALAQHRCWQRRTDAVPA-