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VVLPHGRKGRKERQHMATDHTSDAPDPKQRDLESARFRRDTGYLTTQQGVRVDHTDDALTVGERGPTLLE DFHAREKITHFDHERIPERVVHARGAGAYGYFEPYDDRLAQYTAAKFLTSPGTRTPVFVRFSTVAGSRGS ADTVRDVRGFATKFYTEQGNYDLVGNNFPVFFIQDGIKFPDFVHAVKPEPHNEIPQAQSAHDTLWDFVSL QPETLHAIMWLMSDRALPRSYRMMQGFGVHTFRLVNARGEGTFVKFHWKPRLGVHSLIWDECQKIAGKDP DYNRRDLWEAIESGQYPEWELGVQLVAEDDEFSFDFDLLDATKIIPEEQVPVLPVGKMVLNRNPDNFFAE TEQVAFHTANVVPGIDFTNDPLLQFRNFSYLDTQLIRLGGPNFAQLPVNRPVAQVRTNQHDGYGQHAIPQ GRSSYFKNSIGGGCPALADEDVFRHYTQRVDGQTMRKRAEAFQNHYGQARMFFKSMSPVEAEHIVAAFAF ELGKVEMPEIRSAVVAQLARVDDQLAAQVAAKLGLPEPPEEQVDESAPVSPALSQVTDGGDTIASRRIAV LAADGVDVVGTQRFTELMEQRGAVVEVLAPVAGGTLAGGSGGELRVDRSFTTMASVLYDAVVVACGPRSV STLSDDGYAVHFVTEAYKHLKPIGAYGAGVDLLRKAGIGNRLAEDTDVLNDQAVVTTKAAADELPERFAE EFAAALAQHRCWQRRTDAVPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4069 | katE | - | 100% (721) | catalase HPII |
| M. avium 104 | MAV_4927 | katA | 1e-91 | 40.12% (491) | catalase KatA |
| M. avium 104 | MAV_4926 | katA | 3e-83 | 39.75% (483) | catalase KatA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3446 | - | 0.0 | 52.35% (722) | catalase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2530c | - | 0.0 | 74.86% (704) | catalase CatB |
| M. marinum M | MMAR_5217 | katE | 1e-89 | 42.03% (414) | catalase KatE |
| M. smegmatis MC2 155 | MSMEG_6232 | katA | 1e-109 | 42.75% (538) | catalase KatA |
| M. thermoresistible (build 8) | TH_2895 | - | 0.0 | 51.91% (680) | PUTATIVE Catalase |
| M. ulcerans Agy99 | MUL_4291 | katE | 5e-90 | 42.03% (414) | catalase KatE |
| M. vanbaalenii PYR-1 | Mvan_3201 | - | 0.0 | 53.26% (706) | catalase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4069|M.avium_104 -----------------------------------------------MVL
MAB_2530c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3446|M.gilvum_PYR-GCK -------------------------------------------------M
Mvan_3201|M.vanbaalenii_PYR-1 -------------------------------------------------M
TH_2895|M.thermoresistible__bu MADSNAPKDALKQAKGMAKEVVGAVTGRDDLVDEGRAEQGKRVRPDLAGA
MMAR_5217|M.marinum_M --------------------------------------------------
MUL_4291|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6232|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4069|M.avium_104 PHGRKGR------------KERQHMATDHTSDAPDPKQRDLESARFRRDT
MAB_2530c|M.abscessus_ATCC_199 --------------------------MDRTS---NPKQEQLDTSRVDRAS
Mflv_3446|M.gilvum_PYR-GCK PAAR----------------KRDQSAPAAVSPTGAAKDTQEQQDPRSQSG
Mvan_3201|M.vanbaalenii_PYR-1 PAPR----------------KRDQSAPTRVSPTGASKSTDEQPDPRAQSG
TH_2895|M.thermoresistible__bu PAPQPPSFEEPTEPRPPLPPKPDQGAPELRSATGTPADG--PADTRAQQG
MMAR_5217|M.marinum_M -----------------------------------MAERYT---------
MUL_4291|M.ulcerans_Agy99 -----------------------------------MAERYT---------
MSMEG_6232|M.smegmatis_MC2_155 -----------------------------------MTDVSAQPPDPDDNR
.
MAV_4069|M.avium_104 GYLTTQQGVRVDHTDDALTVGERGPTLLEDFHAREKITHFDHERIPERVV
MAB_2530c|M.abscessus_ATCC_199 GYLTTQQGVRVDHTDDALTAGVRGPTLLEDFHAREIVTHFDHERIPERVV
Mflv_3446|M.gilvum_PYR-GCK RHLTTAQGLRLPDTDHSLKAGSRGPTLMEDFHLREKITHFDHERIPERVV
Mvan_3201|M.vanbaalenii_PYR-1 RFLTTAQGVRIPDTDHSLKAGSRGPTLMEDFHLREKITHFDHERIPERVV
TH_2895|M.thermoresistible__bu RYLTTAQGARLYDTDHSLKAGDRGPTLLQDHHFREKITHFDHERIPERVV
MMAR_5217|M.marinum_M ---TTDAGSPAPSDDQSLTIGPDGPILLQDHYLIEQMAMFNRERIPERQP
MUL_4291|M.ulcerans_Agy99 ---TTDAGNPAPSDDQSLTIGPDGPILLQDHYLIEQMAMFNRERIPERQP
MSMEG_6232|M.smegmatis_MC2_155 DVLTDRQGHPIFDNQNQRSVGARGPATMENYHFLEKMSHFDRERIPERVV
* * :. . * ** :::.: * :: *::******
MAV_4069|M.avium_104 HARGAGAYGYFEPYDDR----LAQYTAAKFLTSPGTRTPVFVRFSTVAGS
MAB_2530c|M.abscessus_ATCC_199 HARGAGAYGYFEPYDAW----LSDFTAAKFLTTPGLRTPVFVRFSTVAGS
Mflv_3446|M.gilvum_PYR-GCK HARGAAAHGVFEAYGN-----AASVTKAAFLSKKGAKTDVFCRFSTVLGS
Mvan_3201|M.vanbaalenii_PYR-1 HARGAAAHGVFEAYGN-----AASITKAAFLASKGKRTDVFCRFSTVLGS
TH_2895|M.thermoresistible__bu HARGAGAHGVFRANGA-----AEKICKAEFLKS-GVETEVFVRFSTVIGN
MMAR_5217|M.marinum_M HAKGGGAHGHFEVT-----HDVSKYTRAAVF-APGAKTDTLIRFSTVAGE
MUL_4291|M.ulcerans_Agy99 HAKGGGAHGHFEVT-----HDVSKYTRAAVF-APGAKTDTLIRFSTVAGE
MSMEG_6232|M.smegmatis_MC2_155 HARGAVAFGYFEATGRWGDEPIERYTRAKLFNTPGKRTDLAIRLSTVIGG
**:*. *.* *. * .: * .* *:*** *
MAV_4069|M.avium_104 RGSADTVRDVRGFATKFYTEQGNYDLVGNNFPVFFIQDGIKFPDFVHAVK
MAB_2530c|M.abscessus_ATCC_199 RGSADTVRDVRGFATKFYTQQGNYDLVGNNFPVFFIQDGIKFPDFVHAVK
Mflv_3446|M.gilvum_PYR-GCK RGSADTVRDTRGFAVKFYTDEGVFDLVGNNMPVFFIQDGIKFPDVVHAAK
Mvan_3201|M.vanbaalenii_PYR-1 RGSADTVRDTRGFAVKFYTEEGTFDLVGNNIPVFFIQDGIKFPDVIHAGK
TH_2895|M.thermoresistible__bu RGSMDTARDTRGFATKFYTGQGTFDLVGNNIPVFFIQDGIKFPDVVHAAK
MMAR_5217|M.marinum_M RGSPDTWRDPRGFALKFYTSEGNFDMVGNNTPVFFMRDPLKFQHFIRSQK
MUL_4291|M.ulcerans_Agy99 RGSPDTWRDPRGFALKFYTSEGNFDMVGNNTPVFFMRDPLKFQHFIRSQK
MSMEG_6232|M.smegmatis_MC2_155 RDSSEVARDPRGFAVKFYTEDGNWDLVGNNLAVFFIRDAIKFPDVIHALK
*.* :. ** **** **** :* :*:**** .***::* :** ..::: *
MAV_4069|M.avium_104 PEPHNEIPQAQSAHDTLWDFVSLQPETLHAIMWLMSDRALPRSYRMMQGF
MAB_2530c|M.abscessus_ATCC_199 PEPDNEIPQAASAHDTLWDFVAEQPETLHAIMWLMSDRALPRSYRMMQGF
Mflv_3446|M.gilvum_PYR-GCK PHPDREIPQAQSAHDTFWDFVSLHTEATHHVFWNMSDRGIPRSYRTMEGF
Mvan_3201|M.vanbaalenii_PYR-1 PHPDREIPQAQSAHDTFWDFVSLHTEATHHVLWNMSDRGIPRSYRTMEGF
TH_2895|M.thermoresistible__bu PHPDREIPQAQTAHDTFWDFFSLHTESAAHTMWAMSDRGIPRSYRTMEGF
MMAR_5217|M.marinum_M RMQ----ATNLRDHNMQWDFWSLSPESAHQVTWLMGDRGIPKSWRHMNGY
MUL_4291|M.ulcerans_Agy99 RMQ----ATNLRDHNMQWDFWSLSPESAHQVTWLMGDRGIPKSWRQMNGY
MSMEG_6232|M.smegmatis_MC2_155 PDP----VTHHQEPARIFDFMSQTPECMHMLVNLFSPRGIPANYRTMQGF
:** : .* :. *.:* .:* *:*:
MAV_4069|M.avium_104 GVHTFRLVNARGEGTFVKFHWKPRLGVHSLIWDECQKIAGKDPDYNRRDL
MAB_2530c|M.abscessus_ATCC_199 GVHTFRLVNDAGEGVFVKFHWKPLLGVHSLLWDECQQIAGKDPDFNRRDL
Mflv_3446|M.gilvum_PYR-GCK GVHTFRLVNRKGETSLVKFHWKPVAGVHSLVWEEAQLAAGFDPDFHRRDM
Mvan_3201|M.vanbaalenii_PYR-1 GVHTFRLVNAKGETSLVKFHWKPVAGVHSLVWEEAQLAAGFDPDFHRRDM
TH_2895|M.thermoresistible__bu GVNTFRLIAPDETTSLVKFHWKPRLGVHSLIWEEAQIIGGVDPDFHRRDL
MMAR_5217|M.marinum_M SSHTYSWINAADEIFWVKYHFITDQGIDFLTQEDADRLAGTDGDYHQRDL
MUL_4291|M.ulcerans_Agy99 SSHTYSWINAADEIFWVKYHFITDQGIDFLTQEDADRLAGTDGDYHQRDL
MSMEG_6232|M.smegmatis_MC2_155 GVNTYRWVNAEGQTHLVKYHWMPKAGVKSLTEEDAAAIQATELGSATKDL
. :*: : **:*: . *:. * ::. . : . :*:
MAV_4069|M.avium_104 WEAIESGQYPEWELGVQLVAEDDEFSFD-FDLLDATKIIPEEQVPVLPVG
MAB_2530c|M.abscessus_ATCC_199 WDAIESGQFPEWELGVQLVPESDEFKFP-FDLLDSTKIIPEEQVPVQPVG
Mflv_3446|M.gilvum_PYR-GCK ADGIEAGAPLEYELGVQVMPDDGTETFEGIDLLDPTKIVPEELVPVQLIG
Mvan_3201|M.vanbaalenii_PYR-1 ADGIEAGAPLEYELGVQVMPDDGTETYAGIDLLDPTKIVPEELVPVQLIG
TH_2895|M.thermoresistible__bu ADAIEAGAFPEWDLGVQVFPDNPEQMFEGIDLLDPTKIVPEELAPVQIIG
MMAR_5217|M.marinum_M YEAIERGDFPSWTLKMQIMGFEEAKSYR-FNPFDLTKVWPHSDYPLIDVG
MUL_4291|M.ulcerans_Agy99 YEAIERGDFPSWTLKMQIMGFEEAKSYR-FNPFDLTKVWPHSDYPLIDVG
MSMEG_6232|M.smegmatis_MC2_155 YEAIERGDYPEWELLVQIMSDDEHPELD-WDPLDDTKVWPENDFPPKLVG
:.** * .: * :*:. . : :* **: *.. * :*
MAV_4069|M.avium_104 KMVLNRNPDNFFAETEQVAFHTANVVPGIDFTNDPLLQFRNFSYLDTQLI
MAB_2530c|M.abscessus_ATCC_199 RMVLDRNPDNFFAETEQVAFHTANVVPGIDFTNDPLLQFRNFSYLDTQLI
Mflv_3446|M.gilvum_PYR-GCK KLTLDRNPTNYFAETEQVAFHLGNLVPGIEVTNDPLLQARLFSYLDTQLT
Mvan_3201|M.vanbaalenii_PYR-1 KLTLNRNPTNYFAETEQVAFHTGNLVPGIEVTNDPLMQARLFSYLDTQLT
TH_2895|M.thermoresistible__bu TLQLNRNVTNFFAETEQVAFHPGHLVPGIDITDDPLMQARLFSYLDTQLL
MMAR_5217|M.marinum_M KLTLDRNVTDYHTEIEQAAFEPNNIVPGTGLSPDKMLLARGFSYSDAHRA
MUL_4291|M.ulcerans_Agy99 KLTLDRNVTDYHTEIEQAAFEPNNIVPGTGLSPDKMLLARGFSYSDAHRA
MSMEG_6232|M.smegmatis_MC2_155 RMVLNRNVDNFFNDNEQLAMGTGVLVDGMDFSEDKMLIGRSFSYSDTQRY
: *:** ::. : ** *: :* * .: * :: * *** *::
MAV_4069|M.avium_104 RLGGPNFAQLPVNRP-VAQVRTNQHDGYGQHAI-PQGRSS---YFKNSIG
MAB_2530c|M.abscessus_ATCC_199 RLGGPNFAQLPINRP-IAEVHNNQRDGFAQHDI-PQGKSS---YFKNTLG
Mflv_3446|M.gilvum_PYR-GCK RLGGPNFNQLPINRP-RCPVNDMLRDGMHQTAI-HTGQAP---YLPNSID
Mvan_3201|M.vanbaalenii_PYR-1 RLGGPNFTQLPINRP-RCPVNDMLRDGMHQTAI-HTGQAP---YRPNSID
TH_2895|M.thermoresistible__bu RLGGPNFAQIPINRP-HAPVNDMLRDGFHQHGV-HAGVAP---YQPNSLD
MMAR_5217|M.marinum_M RLG-TNYRQIPVNSP-IVQVNSYSKDGAMRV---RNASDP--VYAPNSYG
MUL_4291|M.ulcerans_Agy99 RLG-TNYRQIPVNSP-IVQVNSYSKDGAMRV---RNASDP--VYAPNSYG
MSMEG_6232|M.smegmatis_MC2_155 RVG-PNYLQLPVNRPKNAKVATNQQGGPMQYGVDNNGANPHVNYEPSITG
*:* .*: *:*:* * * :.* : . . * . .
MAV_4069|M.avium_104 GGCPALADED--VFRHYTQRVDGQTMR-KRAEAFQNHYGQARMFFKSMSP
MAB_2530c|M.abscessus_ATCC_199 GGCPALAHED--VFRHYTQRVDGHKIR-QRAESFKDFYSQPRMFWNSMSA
Mflv_3446|M.gilvum_PYR-GCK GGEPLVADADEGGYVQTPRPVEGRVGR-VAPASFDDHFTQPAMFYRSLTP
Mvan_3201|M.vanbaalenii_PYR-1 GGEPLVADADEGGYVQSARPVEGRVAR-VAPTSFDDHFTQAAMFYRSLTP
TH_2895|M.thermoresistible__bu GGCPFMASAETGAFIEAPHPLPASAKRRANPATFDDHFSQATLFYRSLHP
MMAR_5217|M.marinum_M GPQADPARAAEVRWHADGQMMRAAYTP---HPEDDDWGQAGTMVREVLDD
MUL_4291|M.ulcerans_Agy99 GPQADPARAAEVRWHADGQMMRAAYTP---HPEDDDWGQAGTMVREVLDD
MSMEG_6232|M.smegmatis_MC2_155 G--LREAQAPTADEYGPEFIGRITRKR---IPRTNDYEQAG-QRYQLMDQ
* * .: . :
MAV_4069|M.avium_104 VEAEHIVAAFAFELGKVEMPE-IRSAVVAQLARVDDQLAAQVAAKLGLPE
MAB_2530c|M.abscessus_ATCC_199 VEAQHIVSAFSFELGKVSAEAGIRERVVAQLNLVEHDLASQVALQLGLPA
Mflv_3446|M.gilvum_PYR-GCK IEQDHIVEAFTFELGKCYEQA-IKERQLEVLANVDADLCAKVAAGLGLPA
Mvan_3201|M.vanbaalenii_PYR-1 IEQAHIVEAFTFELGKCYEQA-VKERQLEVLADVDAELCEQVAQGLGLPA
TH_2895|M.thermoresistible__bu VEQAHVAAAFSFEIGKCYEQT-IKERALAVLANIDAELCATVAAALGLEA
MMAR_5217|M.marinum_M SARDRLVSNIIGHVCKGVKEP-VLSRVFEYWRNVDPDLGKAVEEGVRANS
MUL_4291|M.ulcerans_Agy99 SARDRLASNIIGHICKGVKEP-VLSRVFEYWRNVDPDLGKAVEEGVRANS
MSMEG_6232|M.smegmatis_MC2_155 WEKDDLVKNFVTNISEATRE--VQERMVWHFLMCDDELGLRVGEGLGITV
:. : .: : : . . : :* * :
MAV_4069|M.avium_104 PP-EEQVDESAPVSPALSQVTDGGDTIASRRIAVLAADGVDVVGTQRFTE
MAB_2530c|M.abscessus_ATCC_199 PA-PQSADEALPPSPALSQLSTTRDSIATRRIAVLAADGVDIHGVELLRA
Mflv_3446|M.gilvum_PYR-GCK PK-GNPPKD-VTLSPALSQVVTTPGPVAGRKVAIIADADSDLAGVSKLIK
Mvan_3201|M.vanbaalenii_PYR-1 PK-GKPPAE-VTLSPALSQVVTTPGPVKGRKVAIIADDDSDLAGVAKLVK
TH_2895|M.thermoresistible__bu PRPSVPPVDPETLSPALSQLGST-WPIEGRRVGILTGPDTDVAAVATLVE
MMAR_5217|M.marinum_M S-------------------------------------------------
MUL_4291|M.ulcerans_Agy99 S-------------------------------------------------
MSMEG_6232|M.smegmatis_MC2_155 DD---------VRDLEPLKSQTLSDAEEKRRQNLGKNGPRDVTGLTMTHC
MAV_4069|M.avium_104 LMEQRGAVVEVLAPVAGGTLAGGSGGELRVDRSFTTMASVLYDAVVVACG
MAB_2530c|M.abscessus_ATCC_199 ALEESDAIVEILAPTGGGTLTGESGGELRVDRAMTTMASVLYDAVVVPSG
Mflv_3446|M.gilvum_PYR-GCK AMDKAGVVPMVTAPVGGTLKSGRR--SVIVERTFDTARSIEFDAVVVADG
Mvan_3201|M.vanbaalenii_PYR-1 ALDKAGVIPAIVAPAGGILKSGRR--TLTVDRTFDTARSIEFDAVVVAGG
TH_2895|M.thermoresistible__bu ALLAADLVPHVTAVHGGELGNGEV--SVPVSRTYLTGRSVEFDAIVVAG-
MMAR_5217|M.marinum_M --------------------------------------------------
MUL_4291|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6232|M.smegmatis_MC2_155 VPNERVVMAGK---------------------------------------
MAV_4069|M.avium_104 PRSVSTLSDDGYAVHFVTEAYKHLKPIGAYGAGVDLLRKAGIGNRLAEDT
MAB_2530c|M.abscessus_ATCC_199 AESAWRLARNGFAVHFVSEAYKHLKPVAAYGSGLDLLRAASVVETLATTT
Mflv_3446|M.gilvum_PYR-GCK ALQRHDIK----AVVLLHEMLRHCKPLGAWGNGSAALEAAGIS-------
Mvan_3201|M.vanbaalenii_PYR-1 ALERLDIK----MVVLLHEMLRHCKPLGAWGDARNALQRVDID-------
TH_2895|M.thermoresistible__bu --SPADMR----ARIMVDESYRHLKPVAVLPAGENLVTAAGVP-------
MMAR_5217|M.marinum_M --------------------------------------------------
MUL_4291|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6232|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4069|M.avium_104 DVLNDQAVVTTKAAADELPERFAEEFAAALAQHRCWQR-------RTDAV
MAB_2530c|M.abscessus_ATCC_199 EIVVDDGVVTTTAEANALPAEFVAAFVTAISRHRAWER-------ETEMV
Mflv_3446|M.gilvum_PYR-GCK --LSDPGVVTSGDVS----TAFGTELLAALGLHRVWERADAVMASAVPPV
Mvan_3201|M.vanbaalenii_PYR-1 --LQDPGVVTDDDAS----SSFGAELLAALGLHRVWDRADAVMSSAVAPV
TH_2895|M.thermoresistible__bu --VDTAGVALESDPA----RAA-STLITALGAHRVWDR----------PV
MMAR_5217|M.marinum_M --------------------------------------------------
MUL_4291|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6232|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4069|M.avium_104 PA-----------
MAB_2530c|M.abscessus_ATCC_199 PA-----------
Mflv_3446|M.gilvum_PYR-GCK SASVKTTKRSRKG
Mvan_3201|M.vanbaalenii_PYR-1 RPAAPTTKRTRRR
TH_2895|M.thermoresistible__bu RN-----------
MMAR_5217|M.marinum_M -------------
MUL_4291|M.ulcerans_Agy99 -------------
MSMEG_6232|M.smegmatis_MC2_155 -------------