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SEHLLQVRDLRKSFRVAGKNRLVALDGINLHLDRGETLGLVGESGCGKSTLARTLMMLERPDAGTVTFDG VDPFRLRGKDLLAYRRRVQMVFQDPYASLNSRMTAADIIAEPWRSHKTMYPRRSDRDARVRELLDMVGLS AHAADKYPQEFSGGQRQRLGIARALALDPDVIICDEPVSALDLSVQAQVLNLLNDLQQQLQISYIFISHD LSVVRHVADRVTVMYLGRMIESGRTEDVYNRPGHPYTAALMSAAPKLDATQRRERILLTGEVPSPLNPPS GCRFRTRCWKATDICAQTTPPHAVEPAEETDGSAHIAECHHPMHHAMSVPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6120 | - | - | 100% (332) | peptide transport system ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_0639 | - | 3e-89 | 52.13% (328) | oligopeptide transport ATP-binding protein AppF |
| M. smegmatis MC2 155 | MSMEG_0640 | - | 2e-63 | 43.96% (323) | oligopeptide transport ATP-binding protein OppD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1312c | oppD | 6e-63 | 46.99% (266) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_2259 | - | 1e-58 | 49.37% (239) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
| M. tuberculosis H37Rv | Rv1281c | oppD | 6e-63 | 46.99% (266) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_01122 | - | 5e-61 | 45.63% (263) | putative ABC transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_0722 | - | 4e-53 | 43.45% (267) | putative oligopeptide ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_4138 | oppD | 1e-61 | 46.04% (265) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. avium 104 | MAV_1431 | oppD | 7e-60 | 46.74% (261) | ABC transporter, ATP-binding protein OppD |
| M. thermoresistible (build 8) | TH_2502 | - | 4e-60 | 48.95% (239) | PUTATIVE oligopeptide/dipeptide ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_4001 | oppD | 3e-61 | 45.66% (265) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_1020 | - | 1e-145 | 79.14% (326) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4138|M.marinum_M -----MNPLLEVTDLAVTFPT---ENDPVTAVRGISYQVAPGEVVAMVGE
MUL_4001|M.ulcerans_Agy99 -----MNPLLEVTDLAVTFPT---ENDPVTAVRGISYQVAPGEVVAVVGE
Mb1312c|M.bovis_AF2122/97 -----MSPLLEVTDLAVTFRT---DGDPVTAVRGISYRVEPGEVVAMVGE
Rv1281c|M.tuberculosis_H37Rv -----MSPLLEVTDLAVTFRT---DGDPVTAVRGISYRVEPGEVVAMVGE
MLBr_01122|M.leprae_Br4923 -----MSPLLEVTDLAVTFET---NGEPVTAVRGISYRINAGEVVAMVGE
MAV_1431|M.avium_104 -----MSPLLQVTDLAVTFPA---GDAPVTAVRGISYRIEPGEVVAMVGE
Mflv_2259|M.gilvum_PYR-GCK ------MSLLEVRGLHVTFPT---DTEAVPAVRGLDYHVESGEVVALVGE
TH_2502|M.thermoresistible__bu --------------------------------------------------
MAB_0722|M.abscessus_ATCC_1997 MSHVEASSALSFRSLSVTFST---DSGPVSAVDDVSFDVKPGEVLAVVGE
MSMEG_6120|M.smegmatis_MC2_155 ----MSEHLLQVRDLRKSFRV--AGKNRLVALDGINLHLDRGETLGLVGE
Mvan_1020|M.vanbaalenii_PYR-1 ----MSENLLEVRDVRKSFRVPHAGKNKLCALDGITLDLKRGETLGLVGE
MMAR_4138|M.marinum_M SGSGKSAAAMAVVGLLPEYAKVRGSVRLQGTELLGLADDAMSRFRGKVIG
MUL_4001|M.ulcerans_Agy99 SGSGKSAAAMAVVGLLPEYAKVRGSVRLQGTELLGLADDAMSRFRGKVIG
Mb1312c|M.bovis_AF2122/97 SGSGKSAAAMAVVGLLPEYAQVRGSVRLQGTELLGLADNAMSRFRGKAIG
Rv1281c|M.tuberculosis_H37Rv SGSGKSAAAMAVVGLLPEYAQVRGSVRLQGTELLGLADNAMSRFRGKAIG
MLBr_01122|M.leprae_Br4923 SGSGKSAAAMAVVGLLPEYAQVRGSVRLHNTELVGLADKTMSRFRGKAIG
MAV_1431|M.avium_104 SGSGKSVSAMAVMGLLPEHARVRGSVRLHDTELLGLGDDAMSRLRGRAVG
Mflv_2259|M.gilvum_PYR-GCK SGAGKSAGAMAVVGLLPEWAEVSGSVRLDGDELLGLDDRQMSRIRGARIG
TH_2502|M.thermoresistible__bu --------------------------------------------------
MAB_0722|M.abscessus_ATCC_1997 SGSGKSVSSRTAIRLLPDTARITGSVLLDGRDVTKLSGRELAAMRGKDIA
MSMEG_6120|M.smegmatis_MC2_155 SGCGKSTLARTLMMLERPDA---GTVTFDGVDPFRLRGKDLLAYR-RRVQ
Mvan_1020|M.vanbaalenii_PYR-1 SGCGKSTLARTLMMLERPDE---GTVRFDGVDPFSLKGADLLKFR-RRVQ
MMAR_4138|M.marinum_M TVFQDPMSALTPVYTVGDQIAETIEIHQPTFSKKAAR-RRAVELLELVGI
MUL_4001|M.ulcerans_Agy99 TVFQDPMSALTPVYTVGDQIAETIEIHQPTFSRKAAR-RRAVELLELVGI
Mb1312c|M.bovis_AF2122/97 TVFQDPMSALTPVYTVGDQIAEAIEVHQPRVGKKAAR-RRAVELLDLVGI
Rv1281c|M.tuberculosis_H37Rv TVFQDPMSALTPVYTVGDQIAEAIEVHQPRVGKKAAR-RRAVELLDLVGI
MLBr_01122|M.leprae_Br4923 TVFQDPMSALTPVYTVGDQITEAIKVHQPRVGKKAAH-RRAVELLELVGI
MAV_1431|M.avium_104 MVFQDPMSALTPVYTVGDQIAEAITIHQPRVGRKAAR-DRAVELLELVGI
Mflv_2259|M.gilvum_PYR-GCK TVFQDPMSALTPVYPVGDQIAEAVRIHQRGVDARAAR-ARAVDLLELVGI
TH_2502|M.thermoresistible__bu --------------------------------------------------
MAB_0722|M.abscessus_ATCC_1997 MVFQEPGAALDPLFTIGYQVAEAVRAHS-DMSRVQAR-ARVIELLKLVRL
MSMEG_6120|M.smegmatis_MC2_155 MVFQDPYASLNSRMTAADIIAEPWRSHKTMYPRRSDRDARVRELLDMVGL
Mvan_1020|M.vanbaalenii_PYR-1 MVFQDPYASLNSRMSAAEIIAEPWRSHKGVVQNRHDRDMRVRGLLDLVGL
MMAR_4138|M.marinum_M AQPERRARAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQA
MUL_4001|M.ulcerans_Agy99 AQPERRARAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQA
Mb1312c|M.bovis_AF2122/97 SQPQRRSRAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQA
Rv1281c|M.tuberculosis_H37Rv SQPQRRSRAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQA
MLBr_01122|M.leprae_Br4923 TQPDRRARAFPHELSGGERQRVVIATAIANDPDLLICDEPTTALDVTVQA
MAV_1431|M.avium_104 AQPQRRARAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQA
Mflv_2259|M.gilvum_PYR-GCK SQPAQRARAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQA
TH_2502|M.thermoresistible__bu --------------------------------------------------
MAB_0722|M.abscessus_ATCC_1997 PDPERRYDCYPHQLSGGQKQRVVIAIAIACDPKVIIADEPTTALDVTVQA
MSMEG_6120|M.smegmatis_MC2_155 S--AHAADKYPQEFSGGQRQRLGIARALALDPDVIICDEPVSALDLSVQA
Mvan_1020|M.vanbaalenii_PYR-1 G--AKAAGKYPQEFSGGQRQRIGIARALALNPDVIVCDEPVSALDLSVQA
MMAR_4138|M.marinum_M QILDVLKTARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVEKATVND
MUL_4001|M.ulcerans_Agy99 QILDVLKTARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVEKATVND
Mb1312c|M.bovis_AF2122/97 QILDVLKAARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVND
Rv1281c|M.tuberculosis_H37Rv QILDVLKAARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVND
MLBr_01122|M.leprae_Br4923 QILEVLKTARDVTGAGVLIITHDLGVVTEFADQALVMYAGRVVESAQVST
MAV_1431|M.avium_104 QILEVLKTARDITGAGVLIITHDLGVVAELADRALVMYAGRVVESAAVAS
Mflv_2259|M.gilvum_PYR-GCK QILDVLRTARDVTGAGVLIITHDLGVVAEFADRALVMYAGRAVEAAPVSD
TH_2502|M.thermoresistible__bu --------------------------------------------------
MAB_0722|M.abscessus_ATCC_1997 EILELLRDLRDRIGSAIVLITHNMGVVADIADRVVVMKQGKVVEIAPVER
MSMEG_6120|M.smegmatis_MC2_155 QVLNLLNDLQQQLQISYIFISHDLSVVRHVADRVTVMYLGRMIESGRTED
Mvan_1020|M.vanbaalenii_PYR-1 QVLNLLNDLQEQLQISYIFISHDLSVVRHVADRVAVMYLGRIIENGPTER
MMAR_4138|M.marinum_M LYHNRRMPYTIGLLGSVPRLDATQGTRLVPIPGAPPSLAGLDRGCPFAPR
MUL_4001|M.ulcerans_Agy99 LYHNRRMPYTIGLLGSVPRLDATQGTRLVPIPGAPPSPAGLDRGCPFAPR
Mb1312c|M.bovis_AF2122/97 LYRDRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPR
Rv1281c|M.tuberculosis_H37Rv LYRDRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPR
MLBr_01122|M.leprae_Br4923 LYRERQMPYTVGLLGSVPRLDATQGTRLVPIPGAPPSLAGLQQECPFAPR
MAV_1431|M.avium_104 LYRDRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLDPGCPFAPR
Mflv_2259|M.gilvum_PYR-GCK LYRNRRMPYTAGLLGSVPRLDATQGTRLVPIPGAPPSVTNLPPGCPFTPR
TH_2502|M.thermoresistible__bu --------------------------------------------------
MAB_0722|M.abscessus_ATCC_1997 LFAEPAEPYTRVLLAAVPHLGQGD-----PEHGAEPRED-----------
MSMEG_6120|M.smegmatis_MC2_155 VYNRPGHPYTAALMSAAPKLDATQ--------------------------
Mvan_1020|M.vanbaalenii_PYR-1 VFERSNHPYTAALMSAAPTLDGAQ--------------------------
MMAR_4138|M.marinum_M CPLVIDECRSDEPELIEVGQNHRAACIRTDQVNGRSAADIYGVQTEATEP
MUL_4001|M.ulcerans_Agy99 CPLVIDECRSDEPELIEVGQNHRAACIRTDQVNGRSAADIYGVQTEATEP
Mb1312c|M.bovis_AF2122/97 CPLVIDECLTAEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPA
Rv1281c|M.tuberculosis_H37Rv CPLVIDECLTAEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPA
MLBr_01122|M.leprae_Br4923 CPLVVDECRLREPELVEVRAGHRTACIRTDQVSGRSAADIYGINTDTRTS
MAV_1431|M.avium_104 CPLAIDECRSQEPELLPVGPDHRAACIRTDQVDGRSAADIYGVRTQPHPG
Mflv_2259|M.gilvum_PYR-GCK CPLAVDECSTAEPPLESVAPNHQVACIRNGDVAGRSAAEIYGVSTSPPRT
TH_2502|M.thermoresistible__bu --------------------------------------------------
MAB_0722|M.abscessus_ATCC_1997 ---------IGEP-------------------------------------
MSMEG_6120|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1020|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4138|M.marinum_M APA-DSSVVVRVSDLVKTYPLTKGVLLRRSIGEVRAVDGVNFELRQGHTL
MUL_4001|M.ulcerans_Agy99 APA-DSSVVVRVSDLVKTYPLTKGVLLRRSIGEVRAVDGVSFELRQGHTL
Mb1312c|M.bovis_AF2122/97 ALG-DASVVVRVRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTL
Rv1281c|M.tuberculosis_H37Rv ALG-DASVVVRVRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTL
MLBr_01122|M.leprae_Br4923 ATS-DSSVVVRVRDLVKTYRLTKGVGLRRAIGEIRAVNGVSFELQQGRTL
MAV_1431|M.avium_104 EPA-NSPVVVRVRELSKTYRLTKG-VLRRSAGEVRAVDRISFQLRQGRTL
Mflv_2259|M.gilvum_PYR-GCK EAASEDAVALRVEGLTKTFTLTKGLVFRRRIGEVRAVDGISFELQQGRTL
TH_2502|M.thermoresistible__bu ------------------------XVWRRRIGEVRAVDGISFDLQQGRTL
MAB_0722|M.abscessus_ATCC_1997 --------VLEVSHLVVEFP---GLLGRAAF---RAVDDVSFGIGRGKTL
MSMEG_6120|M.smegmatis_MC2_155 ---------------------------------------------RRERI
Mvan_1020|M.vanbaalenii_PYR-1 ---------------------------------------------RAQRI
: . :
MMAR_4138|M.marinum_M GIVGESGSGKSTTLHQILELAAPQSGSIEVLGTDVTTLTASSRRALRRDI
MUL_4001|M.ulcerans_Agy99 GIVGESGSGKSTTLHQILELAAPQSGSIEVLGTDVTTLTASSRRALRRDI
Mb1312c|M.bovis_AF2122/97 GIVGESGSGKSTTLHEILELAAPQSGSIEVLGTDVATLGTAERRSLRRDI
Rv1281c|M.tuberculosis_H37Rv GIVGESGSGKSTTLHEILELAAPQSGSIEVLGTDVATLGTAERRSLRRDI
MLBr_01122|M.leprae_Br4923 GIVGESGSGKSTTLHEILRLAVPQSGSIEVLGIDVATLNRASRRSMRRNI
MAV_1431|M.avium_104 GIVGESGSGKSTTLHEILELVAPQSGSIEVLGTDVAALSPASRRSLRRDI
Mflv_2259|M.gilvum_PYR-GCK GIVGESGSGKSTTLHQILELSPPQAGTIEVLGRDVAALDRAGRRALRSDL
TH_2502|M.thermoresistible__bu GIVGESGSGKSTTLHEILELTAPQAGSIEVLGSDVARLSAGKRRELRADL
MAB_0722|M.abscessus_ATCC_1997 GLVGESGSGKSTIGRCVAALQQPAAGSVRVLGQEIVGMSQRKLRPLRAKF
MSMEG_6120|M.smegmatis_MC2_155 LLTGEVPSP-----------LNPPSG------------------------
Mvan_1020|M.vanbaalenii_PYR-1 LLKGEVPSP-----------IDPPSG------------------------
: ** * * :*
MMAR_4138|M.marinum_M QVVFQDPVASLDPRLPISDLLAEPLQANGFN-KTDTQDRVAELLDIVGLR
MUL_4001|M.ulcerans_Agy99 QVVFQDPVASLDPRLPISDLLAEPLQANGFN-KTDTQDRVAELLDIVGLR
Mb1312c|M.bovis_AF2122/97 QVVFQDPVASLDPRLPVFDLIAEPLQANGFG-KNETHARVAELLDIVGLR
Rv1281c|M.tuberculosis_H37Rv QVVFQDPVASLDPRLPVFDLIAEPLQANGFG-KNETHARVAELLDIVGLR
MLBr_01122|M.leprae_Br4923 QVVFQDPVASLDPRLPVFELIAEPLHANGFS-KNYTQMRVAELLDIVGLR
MAV_1431|M.avium_104 QVVFQDPVASLDPRLPVFELLAEPLRANGFD-KDHTNARVAELLETVGLR
Mflv_2259|M.gilvum_PYR-GCK QVVFQDPVASLDPRLPVFDILAEPLQDNGFD-KAAIRDRIAELLGVVGLR
TH_2502|M.thermoresistible__bu QVVFQDPVASLDPRLPVFDVLAEPLQAHGFD-HRRIEQRVAELLEIVGLR
MAB_0722|M.abscessus_ATCC_1997 GFVFQDPATALNPKMRVGDCIAEPMWVHRYGDRGKIVARVAELIDAVQLP
MSMEG_6120|M.smegmatis_MC2_155 ---------------------------------CRFRTRCWKATDICAQT
Mvan_1020|M.vanbaalenii_PYR-1 ---------------------------------CRFRTRCWKATDVCATT
* :
MMAR_4138|M.marinum_M RSDASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGII
MUL_4001|M.ulcerans_Agy99 RSDASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGII
Mb1312c|M.bovis_AF2122/97 HGDASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGII
Rv1281c|M.tuberculosis_H37Rv HGDASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGII
MLBr_01122|M.leprae_Br4923 RDDATRYPTEFSGGQKQRIGIARALALQPKILAFDEPVSALDVSIQAGII
MAV_1431|M.avium_104 RADAARYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGII
Mflv_2259|M.gilvum_PYR-GCK REDASRYPAEFSGGQKQRIGIARALALRPKILALDEPVSALDVSIQAGIV
TH_2502|M.thermoresistible__bu RADAGRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGII
MAB_0722|M.abscessus_ATCC_1997 SGTENRYPHELSGGQRQRANLARALALGPDLLVADEPTSALDVSVQAAVL
MSMEG_6120|M.smegmatis_MC2_155 TPPHAVEPAEETDGSA-----HIAECHHPMHHAMS----VPA--------
Mvan_1020|M.vanbaalenii_PYR-1 TPSAAVDP-ELAD--------HTALCHHPLLLEGSGRETVPA--------
* * :. * . * . .
MMAR_4138|M.marinum_M NLLLDLQARFKLSYLFVSHDLSVVKHLAHSVVVMFAGSIVEQGNSQEVFS
MUL_4001|M.ulcerans_Agy99 NLLLDLQAGFKLSYLFVSHDLSVVKHLANSVVVMFAGSIVEQGNSQEVFS
Mb1312c|M.bovis_AF2122/97 NLLLDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFG
Rv1281c|M.tuberculosis_H37Rv NLLLDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFG
MLBr_01122|M.leprae_Br4923 NLLLDLQDRLGLSYLFVSHDLSVIKHLAHQVAVMLAGTIVEQGDSHDVFR
MAV_1431|M.avium_104 NLLLDLQAQFQLSYLFVSHDLSVVKHLAHDVAVMYAGSIVEQGDSSQVFG
Mflv_2259|M.gilvum_PYR-GCK NLLLDLQERFGLAYLFVSHDLSVVRHLAHRVAVMNKGVIVEQGDSDQVFG
TH_2502|M.thermoresistible__bu NLLLDLQERFGLSYLFVSHDLSVVRHLAHRVAVMHRGVIVEKGEADQVFT
MAB_0722|M.abscessus_ATCC_1997 DLFEELQRQWRFACLFISHDLAVVDRLADEVAVLRHGVLEELGPRGEILH
MSMEG_6120|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1020|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4138|M.marinum_M NPQHEYTQRLLGAVPQPIPGNAD------
MUL_4001|M.ulcerans_Agy99 NPQHEYTQRLLGAVPQPIPGNAD------
Mb1312c|M.bovis_AF2122/97 NPKHEYTRRLLGAVPQPDPARRG------
Rv1281c|M.tuberculosis_H37Rv NPKHEYTRRLLGAVPQPDPARRG------
MLBr_01122|M.leprae_Br4923 NPQHDYTRRLLGAIPRPEVG---------
MAV_1431|M.avium_104 NPQHEYTRRLLDAVPQPNPGSRG------
Mflv_2259|M.gilvum_PYR-GCK SPRHDYTRRLLDAVPRPQADRR-------
TH_2502|M.thermoresistible__bu NPRHDYTKRLLAAVPQPEPRHR-------
MAB_0722|M.abscessus_ATCC_1997 NPSRAYTRALVAAVPVPDPVKQRARRNGH
MSMEG_6120|M.smegmatis_MC2_155 -----------------------------
Mvan_1020|M.vanbaalenii_PYR-1 -----------------------------