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KVVLFCGGYGMRMRNGPGDAVPKPMQMVGPRPLIWHVMRYYAHFGHKEFILCLGYGADHIKNYFLTYQEA ASNDFVMSGGQVQLMHSDISDWTISFVDTGLESPIGERLRRVRDYLDGDEYFLANYADVLTDAPLDHMIA EFHLSGAVASMMVVPPQSSFHCVEVSEAGEVKEIIAVSELTIWENGGFFVLSQGIFDLLPPGGDLVADVC GTLAGQGKLFGYRYQGFWKPADTFKERAELEARYHDGDRPWMLWEKSVRAVPEAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5979 | - | - | 100% (266) | transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3292c | manC | 2e-05 | 24.90% (253) | mannose-1-phosphate guanyltransferase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3264c | manB | 3e-05 | 24.90% (253) | D-alpha-D-mannose-1-phosphate guanylyltransferase MANB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3611c | - | 3e-07 | 24.30% (251) | putative sugar-phosphate nucleotidyl transferase |
| M. marinum M | MMAR_2334 | - | 1e-37 | 32.22% (239) | nucleotidyltransferase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0216 | - | 3e-32 | 30.15% (262) | glucose-1-phosphate cytidylyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2334|M.marinum_M -------------------MRE-ETEFRPKPMVEVGGRPVLWHIMKVLGH
Mvan_0216|M.vanbaalenii_PYR-1 ------MKAVILAGGRGTRISE-ESESRPKPMVDIGGRPILWHIMKIYET
Mb3292c|M.bovis_AF2122/97 -MATHQVDAVVLVGGKGTRLRP-LTLSAPKPMLPTAGLPFLTHLLSRIAA
Rv3264c|M.tuberculosis_H37Rv -MATHQVDAVVLVGGKGTRLRP-LTLSAPKPMLPTAGLPFLTHLLSRIAA
MAB_3611c|M.abscessus_ATCC_199 MSGTVKADAVILVGGQGTRLRP-LTLSAPKPMLPIAGFPFLTHVLSRVAA
MSMEG_5979|M.smegmatis_MC2_155 ------MKVVLFCGGYGMRMRNGPGDAVPKPMQMVGPRPLIWHVMRYYAH
: **** . *.: *::
MMAR_2334|M.marinum_M HGISDFVVCTGYKSEYIKDYFSNYGVSNLDFTITLGDQSSIKYHGSHDEF
Mvan_0216|M.vanbaalenii_PYR-1 AGITDFIVLVGYKGYMIKEYFMNYFLHTSDVTIDLATDS-VATIQSKTEP
Mb3292c|M.bovis_AF2122/97 AGIEHVILGTSYKPAVFEAEFG-----------------------DGSAL
Rv3264c|M.tuberculosis_H37Rv AGIEHVILGTSYKPAVFEAEFG-----------------------DGSAL
MAB_3611c|M.abscessus_ATCC_199 AGIDHVVLGTSYKADVFESEFG-----------------------DGSKL
MSMEG_5979|M.smegmatis_MC2_155 FGHKEFILCLGYGADHIKNYFLTYQEAASN---DFVMSGGQVQLMHSDIS
* ..:: .* :: *
MMAR_2334|M.marinum_M NWRVTVADTGLSTMTGGRIKRIHKYVG-DEPFLCTYGDGIADVDIPALLK
Mvan_0216|M.vanbaalenii_PYR-1 -WTVTLLDTGLNTMTGGRLLRAKEYIG-DDTFCFTYGDGVSDLDVRNVID
Mb3292c|M.bovis_AF2122/97 GLQIEYVTEEHPLGTGGGIANVAGKLR-NDTAMVFNGDVLSGADLAQLLD
Rv3264c|M.tuberculosis_H37Rv GLQIEYVTEEHPLGTGGGIANVAGKLR-NDTAMVFNGDVLSGADLAQLLD
MAB_3611c|M.abscessus_ATCC_199 GLQITYVYEEEPLGTGGAIRNVLEHLR-YDTALIFNGDVLSGLDLKDLLA
MSMEG_5979|M.smegmatis_MC2_155 DWTISFVDTGLESPIGERLRRVRDYLDGDEYFLANYADVLTDAPLDHMIA
: * : . : : .* ::. : ::
MMAR_2334|M.marinum_M FHRSHGKIATVTATQP--MSRFGVIDLEQDGAVAKFREKPK-TED-WINI
Mvan_0216|M.vanbaalenii_PYR-1 HHRAERTTVTVTAVQP--PARYGTLEFDE--RRVSFQEKPI-GDGGWVSG
Mb3292c|M.bovis_AF2122/97 FHRSNRADVTLQLVRVGDPRAFGCVPTDEEDRVVAFLEKTEDPPTDQINA
Rv3264c|M.tuberculosis_H37Rv FHRSNRADVTLQLVRVGDPRAFGCVPTDEEDRVVAFLEKTEDPPTDQINA
MAB_3611c|M.abscessus_ATCC_199 QHEQTQADLTLHLVRVGDPRAFGCVPTDSDGKVTAFLEKTEDPPTDQINA
MSMEG_5979|M.smegmatis_MC2_155 EFHLSGAVASMMVVPP--QSSFHCVEVSEAGEVKEIIAVSE--LTIWENG
.. :: . : : .. : . .
MMAR_2334|M.marinum_M GYFIFERGVFDYLE-GDETVLEDQPLRRLAEDR--QIAAFPHHGFWQPMD
Mvan_0216|M.vanbaalenii_PYR-1 GFFVAQPSVLDYIS-GDDTVFEQAPLQRLATDG--ELSAYQHSGFWRGMD
Mb3292c|M.bovis_AF2122/97 GCYVFERNVIDRIPQGREVSVEREVFPALLADGDCKIYGYVDASYWRDMG
Rv3264c|M.tuberculosis_H37Rv GCYVFERNVIDRIPQGREVSVEREVFPALLADGDCKIYGYVDASYWRDMG
MAB_3611c|M.abscessus_ATCC_199 GCYVFRRELIEQIPSGRPVSVEREVFPGLLSSG-AKVCGYVDTSYWRDMG
MSMEG_5979|M.smegmatis_MC2_155 GFFVLSQGIFDLLPPGGDLVAD--VCGTLAGQG--KLFGYRYQGFWKPAD
* :: ::: : * : * . :: .: .:*: .
MMAR_2334|M.marinum_M TFRESQLLNNLWNSGNPPWKVWE---------------------------
Mvan_0216|M.vanbaalenii_PYR-1 TLWDKIYLNDLWDNGKAPWKIWADQLV-----------------------
Mb3292c|M.bovis_AF2122/97 TPEDFVRGSADLVRGIAPSPALRGHRGEQLVHDGAAVSPGALLIGGTVVG
Rv3264c|M.tuberculosis_H37Rv TPEDFVRGSADLVRGIAPSPALRGHRGEQLVHDGAAVSPGALLIGGTVVG
MAB_3611c|M.abscessus_ATCC_199 TPEDFVRGSADLVRGIAPSPAIPEHPGEALVHDGASVAPGALVIGGTVVG
MSMEG_5979|M.smegmatis_MC2_155 TFKERAELEARYHDGDRPWMLWEKSVRAVPEAS-----------------
* : . * *
MMAR_2334|M.marinum_M --------------------------------------------------
Mvan_0216|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3292c|M.bovis_AF2122/97 RGAEIGPGTRLDGAVIFDGVRVEAGCVIERSIIGFGARIGPRALIRDGVI
Rv3264c|M.tuberculosis_H37Rv RGAEIGPGTRLDGAVIFDGVRVEAGCVIERSIIGFGARIGPRALIRDGVI
MAB_3611c|M.abscessus_ATCC_199 RGAEIGPGARLDGAVVFDGARIEAGAVVERSIIGFGARIGPRALVRDGVI
MSMEG_5979|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2334|M.marinum_M -----------------------------------
Mvan_0216|M.vanbaalenii_PYR-1 -----------------------------------
Mb3292c|M.bovis_AF2122/97 GDGADIGARCELLSGARVWPGVFLPDGGIRYSSDV
Rv3264c|M.tuberculosis_H37Rv GDGADIGARCELLSGARVWPGVFLPDGGIRYSSDV
MAB_3611c|M.abscessus_ATCC_199 GDGADIGARCELLRGARVWPGITIPDGGIRYSSDV
MSMEG_5979|M.smegmatis_MC2_155 -----------------------------------