For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MKSTDESPYDAIVVGSGAAGSWAAKELTESGLRVVLLEAGRAVDPARDFPAEAPTGAIGMASRAKAAVSG QFVQAQCAAFFETTKHFYVNDRQNPYTTTPGKRFLWYRGRQLGGRLHTWSRHVPRMSDNEFKSASLRGHG IDWPISYEDVAPFYDIVEQTLGVHGAPSGIASCPDGKFLGPAKTTQIEEKFKTNLENRMPNIRVTYGRTV RYDRERIPLPLRMALGTGNLEIRTDAVVRRLMIDPRTGKAVGVDYVDRSTGAAQAVHGRVVVLCASAIES VRILLNSRTATHPAGVGNSSGHLGRYVCDHVAYAQSGSVAEHEIEPSPAEDGFDFAATGLYIPNFCDPAA VGFPGGYGIQIGIGRGKPTWSMYALGEMQPRFDNRVSLDPRVTDAWGVPAARIECSHSPDEVRMVGHMRS TIREIATAGGLPVENDHDLGRRSIALRLLRSRFFTDYGAYWPGAAVHESGGARMGERPDNSVLNPYCQVW DADNVFVTDGACFVSSGFQNHTLTMMALTVRACRFIAVDYLKC
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5944 | - | - | 100% (533) | glucose-methanol-choline oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_5967 | - | 2e-11 | 23.55% (552) | glucose-methanol-choline oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_0526 | - | 2e-07 | 25.47% (322) | oxidoreductase, GMC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1310 | - | 8e-07 | 26.54% (324) | dehydrogenase FAD flavoprotein GMC oxidoreductase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00389 | choD | 7e-05 | 57.58% (33) | putative cholesterol oxidase |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3093 | - | 1e-35 | 27.43% (576) | glucose-methanol-choline oxidoreductase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5944|M.smegmatis_MC2_155 ------------MKSTDESPYDAIVVGSGAAGSWAAKELTES-GLRVVLL
MAV_3093|M.avium_104 MHSRDLPGERTMRRYADDDEVDLVVVGAGAGGSVLAQRLARA-GWRVVIL
MLBr_00389|M.leprae_Br4923 ----------------MKPDYDVLIIGSGFGGSVSALRLTEK-GYRVGVL
Mb1310|M.bovis_AF2122/97 ----------------MDTQSDYVVVGTGSAGAVVASRLSTDPATTVVAL
. * :::*:* .*: * .*: . * *
MSMEG_5944|M.smegmatis_MC2_155 EAGRAVDPARDFPAEAPTGAIGMASRAKAAVSGQFVQAQCAAFFETTKHF
MAV_3093|M.avium_104 EAGPFWHPDEDWVSDEAG----------------------------SHPL
MLBr_00389|M.leprae_Br4923 EAGRRFA-DEDFAKTSWD----------------------------LRKF
Mb1310|M.bovis_AF2122/97 EAGPRDKNRFIGVPAAFS------------------------------KL
*** :
MSMEG_5944|M.smegmatis_MC2_155 YVNDRQNPYTTTPGKRFL-----WYRGRQLGGRLHTWSRHVPRMSDNEFK
MAV_3093|M.avium_104 YWTQKRIIGGADPIELGK-----NNSGRGVGGSMIHYAGYTPRFHPSDFA
MLBr_00389|M.leprae_Br4923 LWAPKLGCYGIQRIHLLRN--VMILAGAGVGGGSLNYAN-TLYVPPEPFF
Mb1310|M.bovis_AF2122/97 FRSEIDWDYLTEPQPELDGREIYWPRGKVLGGSSSMNAMMWVRGFASDYD
* :** : . :
MSMEG_5944|M.smegmatis_MC2_155 SASLRGHGIDWPISYEDVAPFYDIVEQTLGVHG------APSGIASCPDG
MAV_3093|M.avium_104 TYTLDGVGADWPIRYEDLRRHYEQVELELPVAG------QNWPWGDPHRY
MLBr_00389|M.leprae_Br4923 ANQQWAHITDWHS---ELAPHYDQAQRMLGVVCNPTFTDADRILKEVVDE
Mb1310|M.bovis_AF2122/97 EWAAR-AGPRWSY--ADVLGYFRRIENVTAAWHFVS---GDDSGVTGPLH
* :: .: : .
MSMEG_5944|M.smegmatis_MC2_155 KFLGP----AKTTQIEEKFKTNLENRMPNIRVTYG---------------
MAV_3093|M.avium_104 SFAPHPISGAAAKLWEGALKLGIEMRVGPVGIVNGTFGNRPHCIYRGYCL
MLBr_00389|M.leprae_Br4923 MGFGDTFVPTPVGVFFGPDGTQTPGRTVADPYFGGVGPVRTGCLECGCCM
Mb1310|M.bovis_AF2122/97 ISRQRSPRSVTAAWLAAARECGFAAARPNSPRPEG---------FCETVV
. . *
MSMEG_5944|M.smegmatis_MC2_155 RTVRYDRERIPLPLRMALGTG-NLEIRTDAVVRRLMIDP-RTGKAVGVDY
MAV_3093|M.avium_104 QGCKVNAKASPYVTHLPDALAHDVEIRANCMAARVELD--GSGAARGVVY
MLBr_00389|M.leprae_Br4923 TGCRHGAKNTLVKNYLGLAESAGAQVIPMTTVKGFELRSEGLWEVHTVRT
Mb1310|M.bovis_AF2122/97 TQRRGARFSTADAYLKPAMRRKNLRVLTGATATRVVIDG---DRAVGVEY
: . .: . . . : . *
MSMEG_5944|M.smegmatis_MC2_155 VDRSTGAAQAVHGRVVVLCASAIESVRILLNSRT------ATHPAGVGNS
MAV_3093|M.avium_104 YDEAGGTERLQRAKVVAIAGYSIETPRLLLNSVS------DRFPNGLGNN
MLBr_00389|M.leprae_Br4923 GSWLRRGRRTFTAAHLLLAAGTWGTQRLLFRMRD------QGKLPRLSQR
Mb1310|M.bovis_AF2122/97 QSDGQ-TRIVYARREVVLCAGAVNSPQLLMLSGIGDRDHLAEHDIDTVYH
. : :.. : : ::*:
MSMEG_5944|M.smegmatis_MC2_155 SGHLGRYVCDHVAYAQSG-SVAEHEIEPSPAEDGFDFAATGLYIPNFCDP
MAV_3093|M.avium_104 DDQVGRYVMVQGATQSAG-RWSEEVRMYKAPPP--EVTSEQFYET----D
MLBr_00389|M.leprae_Br4923 LGVLTRTNSESIVGAGTLNVMPDRDLTHGVAITSSIHPTSDTHIEPIRYG
Mb1310|M.bovis_AF2122/97 APEVGCNLLDHLVTVLGFDVEKDSLFAAEKPGQLISYLLRRRGMLTSNVG
: . : .
MSMEG_5944|M.smegmatis_MC2_155 AAVGFPG------GYGIQIGIGRGKPTWSMYALGEMQPRFDNRVSLDPRV
MAV_3093|M.avium_104 SSRGFAR------GFSIQT-VSPMPIGWAEHVLADGH--WGRALREYMRD
MLBr_00389|M.leprae_Br4923 KGSNAMG------LLQTLMTDGPGPEGTDVPRWRQLLHQASEDPRRMLRL
Mb1310|M.bovis_AF2122/97 EAYGFVRSRPELKLPDLELIFAPAPFYDEALVPPAGHGVVFGPILVAPQS
. . . :
MSMEG_5944|M.smegmatis_MC2_155 TD--AWGVPAARIECSHSPDE-VRMVGHMRSTIREIATAGGLPVENDHDL
MAV_3093|M.avium_104 YN--HWATIGVLNELLPQPDNRVTLADEKDAYGIPVARFDYTLCDNDKAN
MLBr_00389|M.leprae_Br4923 INPRRWSERTVIALVMQHLDNSITTFTKRGKLGIRWYSSKQGNGEPNPSW
Mb1310|M.bovis_AF2122/97 RGQITLRSADPHAKPVIEPRYLSDLGGVDRAAMMAGLRICARIAQARPLR
. :
MSMEG_5944|M.smegmatis_MC2_155 GRRSIALRLLRSRFFTDYG------AYWPGAAVHESGGARMGERPDNSVL
MAV_3093|M.avium_104 MAYSTNVIGDILRAADAQD------VLTIERFAHLIGGARMGTRPDNSVV
MLBr_00389|M.leprae_Br4923 IPIGNEVTRRLAAKIDGVAGGTWGELFNIPLTAHFLGGAVIGDNAEHGVI
Mb1310|M.bovis_AF2122/97 DLLGSIARPRNSTELDEAT-LELALATCSHTLYHPMGTCRMGSD-EASVV
. * * . :* : .*:
MSMEG_5944|M.smegmatis_MC2_155 NPYCQVWDADNVFVTDGACFVSSGFQNHTLTMMALTVRACRFIAVDYLKC
MAV_3093|M.avium_104 DSDHRVWGVPNLFVADGSVCPTQGSANPALTIMALASRLAERLAAGKVDT
MLBr_00389|M.leprae_Br4923 DPYHRVYGYPTLYVVDGAAISANLGVNPSLSIAAQAERAASLWPNKGQHD
Mb1310|M.bovis_AF2122/97 DPQLRVRGVDGLRVADASVMPSTVRGHTHAPSVLIGEKAADLIRS-----
:. :* . : *.*.: : : . : .
MSMEG_5944|M.smegmatis_MC2_155 ---------------------------------
MAV_3093|M.avium_104 AAGRRSKAAARG---------------------
MLBr_00389|M.leprae_Br4923 QRPRQGESYRRLAPIAPDHPVVPAEAPGALRWL
Mb1310|M.bovis_AF2122/97 ---------------------------------