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VELNNEFRVAVPAAKTWEVLTDVRRVAPCLPGATLLDVDGDEFTGAVKVKVGPITVSYKGEARFQEKDAG AQRVVLKASGKETRGNGTAAAVVTAQLKDEGADSTLVVVTTDLQISGKAAQFGRGVLSDVASTLIDQFAR SLEAELLGQAGPAGQAAAGETPSDTAASGQPQQGAPINALALAKVMAVPMAKRFAPAIAAVAAAGLIGYL AGRRRSKSQAGLRPEDLQAALLRLVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5881 | - | - | 100% (236) | putative carbon monoxide dehydrogenase subunit G |
| M. smegmatis MC2 155 | MSMEG_0749 | - | 2e-41 | 42.86% (231) | carbon monoxide dehydrogenase subunit G (CoxG) family protein |
| M. smegmatis MC2 155 | MSMEG_2455 | - | 4e-25 | 37.34% (158) | carbon monoxide dehydrogenase subunit G (CoxG) superfamily |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0376c | - | 6e-31 | 43.55% (186) | membrane oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1572 | - | 7e-78 | 65.16% (244) | carbon monoxide dehydrogenase subunit G |
| M. tuberculosis H37Rv | Rv0369c | - | 7e-31 | 43.55% (186) | membrane oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0661 | - | 1e-38 | 39.04% (228) | membrane oxidoreductase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1270 | - | 2e-66 | 61.82% (220) | putative carbon monoxide dehydrogenase subunit G |
| M. ulcerans Agy99 | MUL_0111 | - | 1e-38 | 39.47% (228) | membrane oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5184 | - | 6e-84 | 68.78% (237) | carbon monoxide dehydrogenase subunit G |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1572|M.gilvum_PYR-GCK MELNNEFRVAVPSAKVWEMFTDGERVAPCLPGATLLSTEGDTFHGSVKVK
Mvan_5184|M.vanbaalenii_PYR-1 MELNNEFRVAVPAATVWDVFTDVERVAPCLPGATLLSIDGDTFNGAVKVK
MSMEG_5881|M.smegmatis_MC2_155 MELNNEFRVAVPAAKTWEVLTDVRRVAPCLPGATLLDVDGDEFTGAVKVK
TH_1270|M.thermoresistible__bu VELINEFRVPVPAEQAWDVLTDVERIAPCIPGATLLSVDGDDFTGQVKVK
Mb0376c|M.bovis_AF2122/97 -----------------------------MPGAQLIGHEGDEYLGKVKVK
Rv0369c|M.tuberculosis_H37Rv -----------------------------MPGAQLIGHEGDEYLGKVKVK
MMAR_0661|M.marinum_M MKIANQFTVSAPIEQAWDVLCDLEQVIPLMPGAQLTGHQDDDYLGKVKVK
MUL_0111|M.ulcerans_Agy99 MKIANQFTVSAPIEQAWDVLCDLEQVIPLMPGAQLTGHQDDDYLGKVKVK
:*** * . :.* : * ****
Mflv_1572|M.gilvum_PYR-GCK VGPITVSYKGTATYKEKDAAGQRIVLRAEGKETRGSGTAAATVTAQLKDE
Mvan_5184|M.vanbaalenii_PYR-1 VGPITVSYKGVASYQEKDAVARRIVLRAEGKETRGNGTAAATVTAQLKDE
MSMEG_5881|M.smegmatis_MC2_155 VGPITVSYKGEARFQEKDAGAQRVVLKASGKETRGNGTAAAVVTAQLKDE
TH_1270|M.thermoresistible__bu VGPITVQYKGKASFEQKDTAARRAVIRANGKETRGQGNAAAVVTAELKEE
Mb0376c|M.bovis_AF2122/97 VGPVTSEFSGKVHFVEQDRNQHRAVFDAKGKEARGTGNAAATVAAQLHEV
Rv0369c|M.tuberculosis_H37Rv VGPVTSEFSGKVHFVEQDRNQHRAVFDAKGKEARGTGNAAATVAAQLHEV
MMAR_0661|M.marinum_M VGPVTSEFSGKVHFVERDRDQHRAVIDAKGKESRGTGNAAATVTAQLAEA
MUL_0111|M.ulcerans_Agy99 VGPVTSEFSGKVHFVERDRDQHRAVIDAKGKESRGTGNAAATVTAQLAEA
***:* .:.* . : ::* :* *: *.***:** *.***.*:*:* :
Mflv_1572|M.gilvum_PYR-GCK G-DSTHVAIVTDLAISGKAAQFGRGVLADVSGNLIAQFARSLEAELLGG-
Mvan_5184|M.vanbaalenii_PYR-1 G-ESTYVGIVTDLAISGKAAQFGRGVLADVSSNLIAQFARSLEAELLGG-
MSMEG_5881|M.smegmatis_MC2_155 GADSTLVVVTTDLQISGKAAQFGRGVLSDVASTLIDQFARSLEAELLGQ-
TH_1270|M.thermoresistible__bu G-DSTLCILTTDLTISGKAAQFGRGVLADVAGKLIGQFAERLEADVLSQH
Mb0376c|M.bovis_AF2122/97 G-ERTRVTVDTDLKIVGKLAQFGSGMLQQVSEKLLGQFVDSLEAELAAQ-
Rv0369c|M.tuberculosis_H37Rv G-ERTRVTVDTDLKIVGKLAQFGSGMLQQVSEKLLGQFVDSLEAELAAQ-
MMAR_0661|M.marinum_M G-ERTQVTVDTDLKIVGKLAQFGSGMLQQVSEKLLGQFVDSLEAELASRN
MUL_0111|M.ulcerans_Agy99 G-ERTQVTVDTDLKIVGKLAQFGSGMLQQVSEKLIGQFVDSLEAELASRN
* : * : *** * ** **** *:* :*: .*: **. ***:: .
Mflv_1572|M.gilvum_PYR-GCK ---AAPASAGSAAAAPTHTTQAPSAETA-AAAAQPGGDSVDLLKVVAVPM
Mvan_5184|M.vanbaalenii_PYR-1 ---AAPSGQASENGS------APAAS---VAAAPPAEDSVDLLKVVAVPM
MSMEG_5881|M.smegmatis_MC2_155 ---AGPAGQAAAGETP-----SDTAASG-QPQQGAPINALALAKVMAVPM
TH_1270|M.thermoresistible__bu --TTAPAPQGSADEPA----VQPAPVAA-PTQAPAADASVNMLALVAVPI
Mb0376c|M.bovis_AF2122/97 ----SSESPQ--GTP---------------PATEAAP--IDLLQLADGGQ
Rv0369c|M.tuberculosis_H37Rv ----SSESPQ--GTP---------------PATEAAP--IDLLQLADGGQ
MMAR_0661|M.marinum_M AATAAPESPESPGSPESPASPQPRPVEARKPTTSAEPEPIDLLELAGGDQ
MUL_0111|M.ulcerans_Agy99 AATAAPESPESPGSPESPVSPQPRPVEARKPTTSAEPEPIDLLELAGGDQ
.. . . . : : :
Mflv_1572|M.gilvum_PYR-GCK AKRFAPVLVAATVAGAVGFLIGSRRRRKTPAAVLADDLQAVLARLLS
Mvan_5184|M.vanbaalenii_PYR-1 AKRYAPVLAAAAVAGVIGYLIG-RRRRRGPAAVLADDLQAALARLLS
MSMEG_5881|M.smegmatis_MC2_155 AKRFAPAIAAVAAAGLIGYLAG-RRRSKSQAGLRPEDLQAALLRLVS
TH_1270|M.thermoresistible__bu AKRVAPVAAGLAVGLALGWVLG--RRSGGAA----------------
Mb0376c|M.bovis_AF2122/97 LKKYGSALLAALTVLLLIWVLR--RRR--------------------
Rv0369c|M.tuberculosis_H37Rv LKKYGSALLAALTVLLLIWVLR--RRR--------------------
MMAR_0661|M.marinum_M LKKYGPAVLAVLAVLVLIWVLR--RRR--------------------
MUL_0111|M.ulcerans_Agy99 LKKYGPAVLAVLAVLVLIWVLR--RRR--------------------
*: ... . . : :: **