For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VDDPQPRTASGPTELAPGGTNAVGHMLALLGDEWSLLVMQQALLGATRYGQFMSRLPISNSVLTRRLGTL TADGLLRRHRYQDRPPRDEYLVTARGRALWPILLSIWEWERRWVPEQRDALPGMRHISCGEEFHPLLSCS ACEKEANPGEVVARWGPSGGWQRALPVATTRRRSGSGSGADDRDSPSGLFPQTMSVLGNRWACAILVAAF TGTTRFSTFQKLLAAPPGSVSDRLARFRANGIMTTSPERPEYLLTAKGEAFLPVLVTGLQWAQGWFSAPE GPAVNLTHTACDQVFHPVLRCDRCKEPLTGNSVQTI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5610 | - | - | 100% (316) | putative transcriptional regulator family protein |
| M. smegmatis MC2 155 | MSMEG_6580 | - | 3e-15 | 40.00% (105) | transcriptional regulator family protein |
| M. smegmatis MC2 155 | MSMEG_3013 | - | 7e-14 | 32.48% (117) | putative transcriptional regulator family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3122 | - | 4e-19 | 33.82% (136) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1806 | - | 2e-92 | 56.51% (292) | HxlR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3095 | - | 4e-19 | 33.82% (136) | putative transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3456 | - | 3e-17 | 32.23% (121) | HxlR family transcriptional regulator |
| M. marinum M | MMAR_1555 | - | 3e-17 | 33.10% (145) | transcriptional regulatory protein |
| M. avium 104 | MAV_4183 | - | 1e-13 | 30.65% (124) | putative transcriptional regulator family protein |
| M. thermoresistible (build 8) | TH_4381 | - | 1e-07 | 38.36% (73) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3475 | - | 2e-17 | 33.10% (145) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4941 | - | 5e-94 | 57.24% (297) | HxlR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1806|M.gilvum_PYR-GCK -------------------------MLGLLGDEWTLLIVQRALLGARRYG
Mvan_4941|M.vanbaalenii_PYR-1 ---------------MAGTPNAVARMLSLLGDEWTLLIVQRALLGARRYG
MSMEG_5610|M.smegmatis_MC2_155 MDDPQPRTASGPTELAPGGTNAVGHMLALLGDEWSLLVMQQALLGATRYG
Mb3122|M.bovis_AF2122/97 --------MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFG
Rv3095|M.tuberculosis_H37Rv --------MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFG
MMAR_1555|M.marinum_M --------MGAADLSHRFEGESVGRALELVGERWTLLILREAFFGVQRFG
MUL_3475|M.ulcerans_Agy99 --------MGAADLSHRFEGESVGRALELVGERWTLLILREAFFGVQRFG
MAB_3456|M.abscessus_ATCC_1997 --------MDFTTMRN----CSISNALDVIGERWTLVALREIMLGNRRFE
MAV_4183|M.avium_104 -MTLLQGPLADRDAWSAVGECAIEKTMAVVGTKSAMLIMREAYYGTTRFD
TH_4381|M.thermoresistible__bu ----------------------MRHDGDGVGDRWHT--------DGNDVP
:* . .
Mflv_1806|M.gilvum_PYR-GCK EFLDALPVSNAVLTSRLQSLSATEMLSRNQYQS--NPPRFEYLVTPMSRS
Mvan_4941|M.vanbaalenii_PYR-1 DFAAALPVSNTVLSGRLQSLTADGLLIRSQYQS--NPPRSEYLPTSMGRS
MSMEG_5610|M.smegmatis_MC2_155 QFMSRLPISNSVLTRRLGTLTADGLLRRHRYQD--RPPRDEYLVTARGRA
Mb3122|M.bovis_AF2122/97 QLARNLGIPRPTLSSRLRMLVEVGLFDRVPYSS--DPERHEYRLTEAGRD
Rv3095|M.tuberculosis_H37Rv QLARNLGIPRPTLSSRLRMLVEVGLFDRVPYSS--DPERHEYRLTEAGRD
MMAR_1555|M.marinum_M QLARNLNIPRPTLSSRLRMLVNAGLLDRVPYSQ--DPERHEYRLTDTGHE
MUL_3475|M.ulcerans_Agy99 QLARNLNIPRPTLSSRLRMLVNAGLLDRVPYSQ--DPERHEYRLTDTGHE
MAB_3456|M.abscessus_ATCC_1997 TIVRNTGASRDILATRLRKLVDAGVLEKRRYED--RPPRYEYLLTQSGQA
MAV_4183|M.avium_104 DFARRVGITKAATSARLAELVELGLLKRRPYREPGQRSRDEYVLTQAGID
TH_4381|M.thermoresistible__bu TRVIHIDCADQVRG-ELRCAAYDGLLDAH-------AVAFDRRPEDKGLD
. .* :: : .
Mflv_1806|M.gilvum_PYR-GCK LWPMLTSIWEWERRWVTDHAEPLPRMRHTGCGHEFAPRVVCRSCTAEASG
Mvan_4941|M.vanbaalenii_PYR-1 LWPMLTSIWEWERRWVPEHAEPLPRMHHATCGRPFQPVVTCRACDGPASG
MSMEG_5610|M.smegmatis_MC2_155 LWPILLSIWEWERRWVPEQRDALPGMRHISCGEEFHPLLSCSACEKEANP
Mb3122|M.bovis_AF2122/97 LFAAIVVLMQWGDEYLPRPEGPPIKLRHHTCGEHADPRLICTHCGEEITA
Rv3095|M.tuberculosis_H37Rv LFAAIVVLMQWGDEYLPRPEGPPIKLRHHTCGEHADPRLICTHCGEEITA
MMAR_1555|M.marinum_M LFAAIVVLMQWGDKHLPNPDGPPIVLRHH-CGQFVEPRLICAHCGEEITA
MUL_3475|M.ulcerans_Agy99 LFAAIVVLMQWGDKHLPNPDGPPIVLRHH-CGQFVEPRLICAHCGEEITA
MAB_3456|M.abscessus_ATCC_1997 LRPVLFALMEWGDKFVTK--GPPPSIWEHQCGSVLHIQPTCESCGEAVTF
MAV_4183|M.avium_104 FMPVVWAMFEWGRRHLPG--RHRLQLTHLGCGAEVGVEIRCAEG-HLVPP
TH_4381|M.thermoresistible__bu LYPVPLSMMAWGDRWLPTE-RPSVRLTHLVCGQRLTARLSCSACARPIDR
: . : * . :. : . ** *
Mflv_1806|M.gilvum_PYR-GCK NDVVAQWGPSGSWQRSIPGGTQRRRS-SGH----RSGAAILFPQTMSVIG
Mvan_4941|M.vanbaalenii_PYR-1 KDVAAQWGPSGSWERSIPSGTNRRRS-SGR----RSGAALLFPQTMSVVG
MSMEG_5610|M.smegmatis_MC2_155 GEVVARWGPSGGWQRALPVATTRRRSGSGSGADDRDSPSGLFPQTMSVLG
Mb3122|M.bovis_AF2122/97 RNVTPEPGPGFKAKLASS--------------------------------
Rv3095|M.tuberculosis_H37Rv RNVTPEPGPGFKAKLASS--------------------------------
MMAR_1555|M.marinum_M RNVTPEAGPGFGDAVAAPN-------------------------------
MUL_3475|M.ulcerans_Agy99 RNVTPEAGPGYGDAVAAPN-------------------------------
MAB_3456|M.abscessus_ATCC_1997 DDLTPR-------RLGRVR-------------------------------
MAV_4183|M.avium_104 DELGMRLAKKSG--------------------------------------
TH_4381|M.thermoresistible__bu SAVTFEHR------------------------------------------
: .
Mflv_1806|M.gilvum_PYR-GCK DRWAFAMLVAAFVGMRRFTDFQAQLGAPPTTVADRLTTFTDEGILVSGDG
Mvan_4941|M.vanbaalenii_PYR-1 DRWAFALLVAAFVGVGRFTDFQAQLGAPPATIADRLSVFTDENILGQSGG
MSMEG_5610|M.smegmatis_MC2_155 NRWACAILVAAFTGTTRFSTFQKLLAAPPGSVSDRLARFRANGIMTTSPE
Mb3122|M.bovis_AF2122/97 --------------------------------------------------
Rv3095|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1555|M.marinum_M --------------------------------------------------
MUL_3475|M.ulcerans_Agy99 --------------------------------------------------
MAB_3456|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4183|M.avium_104 --------------------------------------------------
TH_4381|M.thermoresistible__bu --------------------------------------------------
Mflv_1806|M.gilvum_PYR-GCK G--YQFTDKGRAFFPVLVCALSWAQRWFPSPEGPAVILTHTACGRRFDPV
Mvan_4941|M.vanbaalenii_PYR-1 R--YGLTEKGLAFFPVLVCALAWAQRWLPSPEGPAVLLTHTACDRRFAPV
MSMEG_5610|M.smegmatis_MC2_155 RPEYLLTAKGEAFLPVLVTGLQWAQGWFSAPEGPAVNLTHTACDQVFHPV
Mb3122|M.bovis_AF2122/97 --------------------------------------------------
Rv3095|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1555|M.marinum_M --------------------------------------------------
MUL_3475|M.ulcerans_Agy99 --------------------------------------------------
MAB_3456|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4183|M.avium_104 --------------------------------------------------
TH_4381|M.thermoresistible__bu --------------------------------------------------
Mflv_1806|M.gilvum_PYR-GCK LRCDQCQRHLRGAQIRPVP
Mvan_4941|M.vanbaalenii_PYR-1 LVCDQCGNRLRAEQVLPVS
MSMEG_5610|M.smegmatis_MC2_155 LRCDRCKEPLTGNSVQTI-
Mb3122|M.bovis_AF2122/97 -------------------
Rv3095|M.tuberculosis_H37Rv -------------------
MMAR_1555|M.marinum_M -------------------
MUL_3475|M.ulcerans_Agy99 -------------------
MAB_3456|M.abscessus_ATCC_1997 -------------------
MAV_4183|M.avium_104 -------------------
TH_4381|M.thermoresistible__bu -------------------