For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTQATFVAMAMFLGVVIYALFAGADFGSGFYDLTAGDARSGAKVRTLVDHSIGPVWEANHVWLIYILVIW WTGFPRTFAAATTTLFIPLALALTGIVLRGASFAFRKYSATVSQARLFGAIFAASSLISPFFLGTVAGAI ASGRVPAEGYGDRIGSWLNPTSLVGGFLAVATCVFLAGVFLTADAARSGDNGLADSLRRRTLAVGVVTGL IVFAGLYPVAHDAPTLTAGLRTYAAPLLVIALLAGVATVWLVFRRRYAISRIPAAVAVAAVVTGWGVGQY PWLLVDEVTIADAAGADATLTGLLIVVVLAGVIVLPALAYLLRLTQTEEWSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5606 | - | - | 100% (332) | cytochrome bd-I oxidase subunit II |
| M. smegmatis MC2 155 | MSMEG_3232 | cydB | 2e-10 | 26.79% (280) | cytochrome D ubiquinol oxidase, subunit II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1648c | cydB | 2e-11 | 27.74% (310) | integral membrane cytochrome D ubiquinol oxidase (subunit |
| M. gilvum PYR-GCK | Mflv_3586 | - | 5e-16 | 29.78% (319) | cytochrome d ubiquinol oxidase, subunit II |
| M. tuberculosis H37Rv | Rv1622c | cydB | 2e-11 | 27.74% (310) | integral membrane cytochrome D ubiquinol oxidase (subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2631 | - | 1e-13 | 27.49% (331) | cytochrome D ubiquinol oxydase CydB |
| M. marinum M | MMAR_2425 | cydB | 1e-15 | 28.84% (319) | integral membrane cytochrome D ubiquinol oxidase (subunit |
| M. avium 104 | MAV_3165 | cydB | 2e-15 | 29.01% (324) | cytochrome D ubiquinol oxidase, subunit II |
| M. thermoresistible (build 8) | TH_1291 | cydB | 4e-14 | 28.42% (285) | Probable integral membrane cytochrome D ubiquinol oxidase |
| M. ulcerans Agy99 | MUL_1603 | cydB | 7e-16 | 28.21% (319) | integral membrane cytochrome D ubiquinol oxidase (subunit |
| M. vanbaalenii PYR-1 | Mvan_2829 | - | 2e-17 | 30.25% (324) | cytochrome d ubiquinol oxidase, subunit II |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1648c|M.bovis_AF2122/97 ---MVLQELWFGVIAALFLGFFILEGFDFGVGMLMAPFAHVGMGDPETHR
Rv1622c|M.tuberculosis_H37Rv ---MVLQELWFGVIAALFLGFFILEGFDFGVGMLMAPFAHVGMGDPETHR
MMAR_2425|M.marinum_M ---MGLQELWFAVIAVLFLGFFILEGFDFGVGMLMAPFAHFGTGDPEIHR
MUL_1603|M.ulcerans_Agy99 ---MGLQELWFAVIAVLFLGFFILEGFDFGVGMLMAPFAHFGTGDPEIHR
MAV_3165|M.avium_104 ---MGLQEVWFGIIGMLFLGFFILEGFDFGVGMLMEPFARVGIGEPEPLR
Mflv_3586|M.gilvum_PYR-GCK ---MGLQEVWFLLIAVLFLGFLVLEGFDFGVGMLMAPMGTLGPGDPDNRR
Mvan_2829|M.vanbaalenii_PYR-1 ---MGLQELWFLLIAVLFLGFLVLEGFDFGVGMLMSPMGTIGPGDPDDRR
TH_1291|M.thermoresistible__bu VISVGLQELWFILIAALFLGFLVLEGFDFGVGMLMGPLGAAGEGDPEPRR
MAB_2631|M.abscessus_ATCC_1997 MNPTALQQFWFVVVAVLFLGFLVLEGFDFGVGMLMHPLG---RGD-DRRR
MSMEG_5606|M.smegmatis_MC2_155 ---MTQATFVAMAMFLGVVIYALFAGADFGSGFYDLTAG--DARSGAKVR
. : .: : :: * *** *: . . . *
Mb1648c|M.bovis_AF2122/97 RTALNTIGPVWDGNEVWLITAGAAIFAAFPGWYATVFSALYLPLLAILFG
Rv1622c|M.tuberculosis_H37Rv RTALNTIGPVWDGNEVWLITAGAAIFAAFPGWYATVFSALYLPLLAILFG
MMAR_2425|M.marinum_M RTALNTIGPVWDGNEVWLITGGAAMFAAFPGWYATVFSTLYLPLLAILFG
MUL_1603|M.ulcerans_Agy99 RTALNTIGPVWDGNEVWLITSGAAMFAAFPGWYATVFSTLYLPLLAILFG
MAV_3165|M.avium_104 RTALNTIGPVWDGNEVWLIVGGAAMFAAFPGWYATVFSTLYLPLLAILFG
Mflv_3586|M.gilvum_PYR-GCK RAVLNTIGPVWDANEVWLITAGAAMFAAFPVWYATLFSALYLPLLAILFG
Mvan_2829|M.vanbaalenii_PYR-1 RAVLNTIGPVWDANEVWLITAGAAMFAAFPNWYATLFSALYLPLLAILFG
TH_1291|M.thermoresistible__bu RAVLNTIGPVWDANEVWLITAGASMFAAFPNWYATLFSALYLPLLAILFG
MAB_2631|M.abscessus_ATCC_1997 RAVLNTIGPVWDGNEVWLITAGGAMFAAFPHWYATVFSGLYLPLLLILVS
MSMEG_5606|M.smegmatis_MC2_155 TLVDHSIGPVWEANHVWLIYILVIWWTGFPRTFAAATTTLFIPLALALTG
. ::*****:.*.**** ::.** :*: : *::** * .
Mb1648c|M.bovis_AF2122/97 MILRAVAIEWRGKIDDPKWRTGADFGIAAGSWLPALLWGVAFAILVRG-L
Rv1622c|M.tuberculosis_H37Rv MILRAVAIEWRGKIDDPKWRTGADFGIAAGSWLPALLWGVAFAILVRG-L
MMAR_2425|M.marinum_M MIVRSVAIEWRGKVDDPKWRALADFGIAAGSWLPAILWGVAFAILVRG-L
MUL_1603|M.ulcerans_Agy99 MIVRSVAIEWRGKVDDSKWRALADFGIAAGSWLPAILWGVAFAILVRG-L
MAV_3165|M.avium_104 MILRAVAIEWRGKIDDTKWRGWADFGIAAGSWLPAVLWGVAFAVLVRG-L
Mflv_3586|M.gilvum_PYR-GCK MILRIVGIEWRGKINDPQWRRWADYGIAAGSWLPAVLWGVAFAILLRG-L
Mvan_2829|M.vanbaalenii_PYR-1 MILRIVGIEWRGKINDPQWRRWADIGIALGSWLPAVLWGVAFAILLRG-L
TH_1291|M.thermoresistible__bu MIVRIVGIEWRGKIDDERWRKWADAGIAVGSWLPAVLWGVAFAILLRG-L
MAB_2631|M.abscessus_ATCC_1997 MIVRIVAIEWRGKIDDPRWRARCDLGIAIGSWIPALLWGVAFSSLLAG-L
MSMEG_5606|M.smegmatis_MC2_155 IVLRGASFAFRKYSATVSQARLFGAIFAASSLISPFFLGTVAGAIASGRV
:::* ..: :* . :* .* :...: *.. . : * :
Mb1648c|M.bovis_AF2122/97 PVDANGHVALSIPDVLNAYTLLGGLATAGLFSLYGAVFIALKTSGPIR--
Rv1622c|M.tuberculosis_H37Rv PVDANGHVALSIPDVLNAYTLLGGLATAGLFSLYGAVFIALKTSGPIR--
MMAR_2425|M.marinum_M PVDADGHVALSIGDVLNAYTLLGGLATAGLFLFYGAVFVALKTAGPIR--
MUL_1603|M.ulcerans_Agy99 PVDANGRLALSIGDVLNAYTLLGGLATAGLFLFYGAVFVALKTAGPIR--
MAV_3165|M.avium_104 PVDADGHIHLSVTDVLNPYTLLGGLATAGLFLLYGAVFVALKTSGAIR--
Mflv_3586|M.gilvum_PYR-GCK PIDAEGRTDIAFGDVLSPYTLLGGLATGSLFLFYGSVYLALKTSGVLR--
Mvan_2829|M.vanbaalenii_PYR-1 PIDADGRAHPGIGDILSAYTLLGGLATASLFLFYGSVYLALRTAGALH--
TH_1291|M.thermoresistible__bu PIDADGRAHPGLTDVLNGYTLLGGLATASLFAFYGAVFVALKTAGSVR--
MAB_2631|M.abscessus_ATCC_1997 PVDGAKQLTLTVGDVLRPYVLLGGVVFVGLFALHGALFICLKTSGVVR--
MSMEG_5606|M.smegmatis_MC2_155 PAEGYG---DRIGSWLNPTSLVGGFLAVATCVFLAGVFLTADAARSGDNG
* :. . . * *:**. . : ..::: ::
Mb1648c|M.bovis_AF2122/97 -DDAYRFAVWLSLPVAGLVAGFGLWTQLAYG-------KDWTWLVLAVAG
Rv1622c|M.tuberculosis_H37Rv -DDAYRFAVWLSLPVAGLVAGFGLWTQLAYG-------KDWTWLVLAVAG
MMAR_2425|M.marinum_M -DDAYRFAVVLSLPVTVLVAGFGVWTQLAYG-------KQWTWALLGVAV
MUL_1603|M.ulcerans_Agy99 -DDAYRFAVVLSLPVTVLVAGFGVWTQLAYG-------KQWTWALLGVAV
MAV_3165|M.avium_104 -DDAYRFAVWLSLPVTGLVAGFGLWTQLGYG-------KDWTWLVLAVAV
Mflv_3586|M.gilvum_PYR-GCK -EDAFRVGKALSVPVIVLAGGFGLWTQLAYG-------RPWTWIALAAAV
Mvan_2829|M.vanbaalenii_PYR-1 -DDSFRVARVLSLPVIVLAGGFGLWTQLAYG-------KPWTWLALAVAV
TH_1291|M.thermoresistible__bu -ADAFRFAKWLSAPVIVLAGGFGLWTQLAHG-------TDWTWVALGVAV
MAB_2631|M.abscessus_ATCC_1997 -DDAVAWARKLAAPVIVGAGGYGLWTQLAYG-------ASWTWIALGTAA
MSMEG_5606|M.smegmatis_MC2_155 LADSLRRRTLAVGVVTGLIVFAGLYPVAHDAPTLTAGLRTYAAPLLVIAL
*: * *::. . :: * *
Mb1648c|M.bovis_AF2122/97 CAQAAATVLVWRRVSDGWAFMCTLIVVAAVVVLLFGALYPNLVPSTLNPQ
Rv1622c|M.tuberculosis_H37Rv CAQAAATVLVWRRVSDGWAFMCTLIVVAAVVVLLFGALYPNLVPSTLNPQ
MMAR_2425|M.marinum_M VAQLAAVLLVWRRVSDGWAFLCIAVVVAAVVLLLFGALYPNLVPSTLNER
MUL_1603|M.ulcerans_Agy99 VAQMAAVLLVWRRVSDGWAFLCIAVVVAAVVLLLFGALYPNLVPSTLNER
MAV_3165|M.avium_104 VAQVAAVLLVWRRASDGWAFTCLALVVAAVVILLFGALYPNLVPSTLDSR
Mflv_3586|M.gilvum_PYR-GCK VALLAAVALMWGQTREGIAFVSMVVVIAAVAVLIFGSMYPNLLPSTLNPE
Mvan_2829|M.vanbaalenii_PYR-1 VALLISVALVWKGFREGVAFVSMVVVIAAVAVLIFGSMYPNLLPSTLNPE
TH_1291|M.thermoresistible__bu VALLVAVGLMWAGRREGWAFFNTVVVITAVTVLIFGAMYPNLLPSTLNPE
MAB_2631|M.abscessus_ATCC_1997 LS-LVAAALASRISRDGWAFACTCLTVVAVVALLFGSLYPNLIVSNLDPA
MSMEG_5606|M.smegmatis_MC2_155 LAGVATVWLVFRR-RYAISRIPAAVAVAAVVTGWGVGQYPWLLVD-----
: :. * . : :.:.**. . ** *: .
Mb1648c|M.bovis_AF2122/97 WSLTIHNASSTPYTLKIMTWVTAFFAPLTVAYQTWTYWVFRQRISAERIP
Rv1622c|M.tuberculosis_H37Rv WSLTIHNASSTPYTLKIMTWVTAFFAPLTVAYQTWTYWVFRQRISAERIP
MMAR_2425|M.marinum_M WNVTIYNASSTPYTLKIMTWVTALFAPLTVVYQAWTYWVFRQRISAERIP
MUL_1603|M.ulcerans_Agy99 WNVTVYNASSTPYTLKIMTWVTALFAPLTVVYQAWTYWVFRQRISAERIP
MAV_3165|M.avium_104 WSLTIYNASSTHYTLKVMTWVTAIMAPVTVVYQAWTYWVFRQRLSADRIP
Mflv_3586|M.gilvum_PYR-GCK WSVTIYNGSSTPYTLRIMTWASLALLPLVLGYQAWSYWVFRKRVTAESIP
Mvan_2829|M.vanbaalenii_PYR-1 WSVTIYNGSSTPYTLRIMTWASLTLLPLVLAYQAWSYWVFRKRITAESIP
TH_1291|M.thermoresistible__bu WSVTIYNGSSTPYTLQIMSWAALTLLPLVLGYQAWTYWVFRKRISTDAIP
MAB_2631|M.abscessus_ATCC_1997 YNLTIVNASSSPYTLKVMSWAAAITAPVVLVYQGWTYWVFRQRISAEQIP
MSMEG_5606|M.smegmatis_MC2_155 -EVTIADAAGADATLTGLLIVVVLAGVIVLPALAYLLRLTQTEEWSR---
.:*: :.:.: ** : . :.: : : : . :
Mb1648c|M.bovis_AF2122/97 PPTGLARRAP----------------------------------------
Rv1622c|M.tuberculosis_H37Rv PPTGLARRAP----------------------------------------
MMAR_2425|M.marinum_M PSIGLARRPS----------------------------------------
MUL_1603|M.ulcerans_Agy99 PSIGLWLGAPPDRKGLDHPRAAGPAAVAGVGRVAVLSDRLGDLRSGHLGL
MAV_3165|M.avium_104 APVGLTRRPS----------------------------------------
Mflv_3586|M.gilvum_PYR-GCK ESIGLTRRVS----------------------------------------
Mvan_2829|M.vanbaalenii_PYR-1 ASIGLSRRPS----------------------------------------
TH_1291|M.thermoresistible__bu PPIGLPR-------------------------------------------
MAB_2631|M.abscessus_ATCC_1997 DPVGLTVR------------------------------------------
MSMEG_5606|M.smegmatis_MC2_155 --------------------------------------------------
Mb1648c|M.bovis_AF2122/97 --------------------------------------------------
Rv1622c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2425|M.marinum_M --------------------------------------------------
MUL_1603|M.ulcerans_Agy99 CHCVGDRAGEHGRARRQRPLGTVSTLLAGLAVDVVGAVGVACGDALAAGA
MAV_3165|M.avium_104 --------------------------------------------------
Mflv_3586|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2829|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1291|M.thermoresistible__bu --------------------------------------------------
MAB_2631|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5606|M.smegmatis_MC2_155 --------------------------------------------------
Mb1648c|M.bovis_AF2122/97 --------------------------------------------------
Rv1622c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2425|M.marinum_M --------------------------------------------------
MUL_1603|M.ulcerans_Agy99 PGPARGQRGDRRAQWAGAGVGDGPPAQRIGGTTRCRRGGGNPRTGRLATL
MAV_3165|M.avium_104 --------------------------------------------------
Mflv_3586|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2829|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1291|M.thermoresistible__bu --------------------------------------------------
MAB_2631|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5606|M.smegmatis_MC2_155 --------------------------------------------------
Mb1648c|M.bovis_AF2122/97 --------------------------------------------------
Rv1622c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2425|M.marinum_M --------------------------------------------------
MUL_1603|M.ulcerans_Agy99 FHRLPAHAVSCGDPDPGHRGDDRGLRREVGADRGDHPSTDPGLHGLDRVG
MAV_3165|M.avium_104 --------------------------------------------------
Mflv_3586|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2829|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1291|M.thermoresistible__bu --------------------------------------------------
MAB_2631|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5606|M.smegmatis_MC2_155 --------------------------------------------------
Mb1648c|M.bovis_AF2122/97 --
Rv1622c|M.tuberculosis_H37Rv --
MMAR_2425|M.marinum_M --
MUL_1603|M.ulcerans_Agy99 YR
MAV_3165|M.avium_104 --
Mflv_3586|M.gilvum_PYR-GCK --
Mvan_2829|M.vanbaalenii_PYR-1 --
TH_1291|M.thermoresistible__bu --
MAB_2631|M.abscessus_ATCC_1997 --
MSMEG_5606|M.smegmatis_MC2_155 --