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MGLQEVWFGIIGMLFLGFFILEGFDFGVGMLMEPFARVGIGEPEPLRRTALNTIGPVWDGNEVWLIVGGA AMFAAFPGWYATVFSTLYLPLLAILFGMILRAVAIEWRGKIDDTKWRGWADFGIAAGSWLPAVLWGVAFA VLVRGLPVDADGHIHLSVTDVLNPYTLLGGLATAGLFLLYGAVFVALKTSGAIRDDAYRFAVWLSLPVTG LVAGFGLWTQLGYGKDWTWLVLAVAVVAQVAAVLLVWRRASDGWAFTCLALVVAAVVILLFGALYPNLVP STLDSRWSLTIYNASSTHYTLKVMTWVTAIMAPVTVVYQAWTYWVFRQRLSADRIPAPVGLTRRPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3165 | cydB | - | 100% (346) | cytochrome D ubiquinol oxidase, subunit II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1648c | cydB | 1e-172 | 83.33% (342) | integral membrane cytochrome D ubiquinol oxidase (subunit |
| M. gilvum PYR-GCK | Mflv_3586 | - | 1e-141 | 65.90% (346) | cytochrome d ubiquinol oxidase, subunit II |
| M. tuberculosis H37Rv | Rv1622c | cydB | 1e-172 | 83.33% (342) | integral membrane cytochrome D ubiquinol oxidase (subunit |
| M. leprae Br4923 | MLBr_02409 | - | 3e-05 | 28.65% (178) | putative cytochrome C biogenesis protein |
| M. abscessus ATCC 19977 | MAB_2631 | - | 1e-124 | 62.87% (342) | cytochrome D ubiquinol oxydase CydB |
| M. marinum M | MMAR_2425 | cydB | 1e-174 | 82.95% (346) | integral membrane cytochrome D ubiquinol oxidase (subunit |
| M. smegmatis MC2 155 | MSMEG_3232 | cydB | 1e-138 | 67.71% (350) | cytochrome D ubiquinol oxidase, subunit II |
| M. thermoresistible (build 8) | TH_1291 | cydB | 1e-144 | 67.93% (343) | Probable integral membrane cytochrome D ubiquinol oxidase |
| M. ulcerans Agy99 | MUL_1603 | cydB | 1e-169 | 81.82% (341) | integral membrane cytochrome D ubiquinol oxidase (subunit |
| M. vanbaalenii PYR-1 | Mvan_2829 | - | 1e-143 | 66.18% (346) | cytochrome d ubiquinol oxidase, subunit II |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1648c|M.bovis_AF2122/97 ---MVLQELWFGVIAALFLGFF-ILEGFDFGVGMLMAPFAHVGM---GDP
Rv1622c|M.tuberculosis_H37Rv ---MVLQELWFGVIAALFLGFF-ILEGFDFGVGMLMAPFAHVGM---GDP
MMAR_2425|M.marinum_M ---MGLQELWFAVIAVLFLGFF-ILEGFDFGVGMLMAPFAHFGT---GDP
MUL_1603|M.ulcerans_Agy99 ---MGLQELWFAVIAVLFLGFF-ILEGFDFGVGMLMAPFAHFGT---GDP
MAV_3165|M.avium_104 ---MGLQEVWFGIIGMLFLGFF-ILEGFDFGVGMLMEPFARVGI---GEP
Mflv_3586|M.gilvum_PYR-GCK ---MGLQEVWFLLIAVLFLGFL-VLEGFDFGVGMLMAPMGTLGP---GDP
Mvan_2829|M.vanbaalenii_PYR-1 ---MGLQELWFLLIAVLFLGFL-VLEGFDFGVGMLMSPMGTIGP---GDP
TH_1291|M.thermoresistible__bu VISVGLQELWFILIAALFLGFL-VLEGFDFGVGMLMGPLGAAGE---GDP
MSMEG_3232|M.smegmatis_MC2_155 ---MGLQELWFILLAVLFLGFF-LLEGFDFGVGMLMSFFGRAAEKRGQDP
MAB_2631|M.abscessus_ATCC_1997 MNPTALQQFWFVVVAVLFLGFL-VLEGFDFGVGMLMHPLGRGDD------
MLBr_02409|M.leprae_Br4923 ---MNTLHVNIGLACYSDWAFTSAVVALVVALLLLAYELAYVGS---RRL
.. : : .* : .: ..: :* :.
Mb1648c|M.bovis_AF2122/97 ETHRRTALNTIGPVWDGNEVWLITAGAAIFAAFPGWYATVFSALYLPLLA
Rv1622c|M.tuberculosis_H37Rv ETHRRTALNTIGPVWDGNEVWLITAGAAIFAAFPGWYATVFSALYLPLLA
MMAR_2425|M.marinum_M EIHRRTALNTIGPVWDGNEVWLITGGAAMFAAFPGWYATVFSTLYLPLLA
MUL_1603|M.ulcerans_Agy99 EIHRRTALNTIGPVWDGNEVWLITSGAAMFAAFPGWYATVFSTLYLPLLA
MAV_3165|M.avium_104 EPLRRTALNTIGPVWDGNEVWLIVGGAAMFAAFPGWYATVFSTLYLPLLA
Mflv_3586|M.gilvum_PYR-GCK DNRRRAVLNTIGPVWDANEVWLITAGAAMFAAFPVWYATLFSALYLPLLA
Mvan_2829|M.vanbaalenii_PYR-1 DDRRRAVLNTIGPVWDANEVWLITAGAAMFAAFPNWYATLFSALYLPLLA
TH_1291|M.thermoresistible__bu EPRRRAVLNTIGPVWDANEVWLITAGASMFAAFPNWYATLFSALYLPLLA
MSMEG_3232|M.smegmatis_MC2_155 EPYRRAALNTIGPVWDGNEVWLITAGGAMFAAFPEMYASMFSGLYLALLV
MAB_2631|M.abscessus_ATCC_1997 -RRRRAVLNTIGPVWDGNEVWLITAGGAMFAAFPHWYATVFSGLYLPLLL
MLBr_02409|M.leprae_Br4923 DNRTRVVPGSVAADS-GTPGIVVDSLQRPFGERVGQAG--LAVAYLGIGL
*.. .::.. .. :: . *. . :: ** :
Mb1648c|M.bovis_AF2122/97 ILFGMILR---AVAIEWRGKIDDPKWRTGADFGIAAGSWLPALLWGVAFA
Rv1622c|M.tuberculosis_H37Rv ILFGMILR---AVAIEWRGKIDDPKWRTGADFGIAAGSWLPALLWGVAFA
MMAR_2425|M.marinum_M ILFGMIVR---SVAIEWRGKVDDPKWRALADFGIAAGSWLPAILWGVAFA
MUL_1603|M.ulcerans_Agy99 ILFGMIVR---SVAIEWRGKVDDSKWRALADFGIAAGSWLPAILWGVAFA
MAV_3165|M.avium_104 ILFGMILR---AVAIEWRGKIDDTKWRGWADFGIAAGSWLPAVLWGVAFA
Mflv_3586|M.gilvum_PYR-GCK ILFGMILR---IVGIEWRGKINDPQWRRWADYGIAAGSWLPAVLWGVAFA
Mvan_2829|M.vanbaalenii_PYR-1 ILFGMILR---IVGIEWRGKINDPQWRRWADIGIALGSWLPAVLWGVAFA
TH_1291|M.thermoresistible__bu ILFGMIVR---IVGIEWRGKIDDERWRKWADAGIAVGSWLPAVLWGVAFA
MSMEG_3232|M.smegmatis_MC2_155 ILCAMILR---IVAIEWRGKIDDPGWRRWADTGIAVGSWVPAILWGVAFA
MAB_2631|M.abscessus_ATCC_1997 ILVSMIVR---IVAIEWRGKIDDPRWRARCDLGIAIGSWIPALLWGVAFS
MLBr_02409|M.leprae_Br4923 LLACILLRGLATLRVPWGNMYEFINLTCFSELVAGA-----IVLRRRQYR
:* :::* : : * . : .: . :* :
Mb1648c|M.bovis_AF2122/97 ILVRGLPVDANGHVALS-IPDVLNAYTLLGGLATAGLFSLYGAVFIALKT
Rv1622c|M.tuberculosis_H37Rv ILVRGLPVDANGHVALS-IPDVLNAYTLLGGLATAGLFSLYGAVFIALKT
MMAR_2425|M.marinum_M ILVRGLPVDADGHVALS-IGDVLNAYTLLGGLATAGLFLFYGAVFVALKT
MUL_1603|M.ulcerans_Agy99 ILVRGLPVDANGRLALS-IGDVLNAYTLLGGLATAGLFLFYGAVFVALKT
MAV_3165|M.avium_104 VLVRGLPVDADGHIHLS-VTDVLNPYTLLGGLATAGLFLLYGAVFVALKT
Mflv_3586|M.gilvum_PYR-GCK ILLRGLPIDAEGRTDIA-FGDVLSPYTLLGGLATGSLFLFYGSVYLALKT
Mvan_2829|M.vanbaalenii_PYR-1 ILLRGLPIDADGRAHPG-IGDILSAYTLLGGLATASLFLFYGSVYLALRT
TH_1291|M.thermoresistible__bu ILLRGLPIDADGRAHPG-LTDVLNGYTLLGGLATASLFAFYGAVFVALKT
MSMEG_3232|M.smegmatis_MC2_155 SLVRGLPVDADKQIHLSFFGDLLNAYTLLGGLATCALFAFHGAVFVSLKT
MAB_2631|M.abscessus_ATCC_1997 SLLAGLPVDGAKQLTLT-VGDVLRPYVLLGGVVFVGLFALHGALFICLKT
MLBr_02409|M.leprae_Br4923 PLWVFLLVSVLILLTIS--GRWLYANAAPVIPALQSYWLPIHVSVVSLGS
* * :. * . . . : :.* :
Mb1648c|M.bovis_AF2122/97 SGPIRDDAYRFAVWLSLPVAGLVAGFGLWTQLAYGKDWTWLVLAVAGCAQ
Rv1622c|M.tuberculosis_H37Rv SGPIRDDAYRFAVWLSLPVAGLVAGFGLWTQLAYGKDWTWLVLAVAGCAQ
MMAR_2425|M.marinum_M AGPIRDDAYRFAVVLSLPVTVLVAGFGVWTQLAYGKQWTWALLGVAVVAQ
MUL_1603|M.ulcerans_Agy99 AGPIRDDAYRFAVVLSLPVTVLVAGFGVWTQLAYGKQWTWALLGVAVVAQ
MAV_3165|M.avium_104 SGAIRDDAYRFAVWLSLPVTGLVAGFGLWTQLGYGKDWTWLVLAVAVVAQ
Mflv_3586|M.gilvum_PYR-GCK SGVLREDAFRVGKALSVPVIVLAGGFGLWTQLAYGRPWTWIALAAAVVAL
Mvan_2829|M.vanbaalenii_PYR-1 AGALHDDSFRVARVLSLPVIVLAGGFGLWTQLAYGKPWTWLALAVAVVAL
TH_1291|M.thermoresistible__bu AGSVRADAFRFAKWLSAPVIVLAGGFGLWTQLAHGTDWTWVALGVAVVAL
MSMEG_3232|M.smegmatis_MC2_155 SGEIRTDAFGFARLLALPATALVAAFGVWTQVAHGTGWTWIVLAAAVIAQ
MAB_2631|M.abscessus_ATCC_1997 SGVVRDDAVAWARKLAAPVIVGAGGYGLWTQLAYGASWTWIALGTAALS-
MLBr_02409|M.leprae_Br4923 GIFLVAGIASILFLLSTSRLVASDPEGAKALARLVRRFP----DAQTLDR
. : . *: . * : :. .
Mb1648c|M.bovis_AF2122/97 AAATVLVWRRVSDGWAFMCTLIVVAAVVVLLFGALYPNLVPSTLNPQWSL
Rv1622c|M.tuberculosis_H37Rv AAATVLVWRRVSDGWAFMCTLIVVAAVVVLLFGALYPNLVPSTLNPQWSL
MMAR_2425|M.marinum_M LAAVLLVWRRVSDGWAFLCIAVVVAAVVLLLFGALYPNLVPSTLNERWNV
MUL_1603|M.ulcerans_Agy99 MAAVLLVWRRVSDGWAFLCIAVVVAAVVLLLFGALYPNLVPSTLNERWNV
MAV_3165|M.avium_104 VAAVLLVWRRASDGWAFTCLALVVAAVVILLFGALYPNLVPSTLDSRWSL
Mflv_3586|M.gilvum_PYR-GCK LAAVALMWGQTREGIAFVSMVVVIAAVAVLIFGSMYPNLLPSTLNPEWSV
Mvan_2829|M.vanbaalenii_PYR-1 LISVALVWKGFREGVAFVSMVVVIAAVAVLIFGSMYPNLLPSTLNPEWSV
TH_1291|M.thermoresistible__bu LVAVGLMWAGRREGWAFFNTVVVITAVTVLIFGAMYPNLLPSTLNPEWSV
MSMEG_3232|M.smegmatis_MC2_155 LVAVAQVFRGSGEGWAFGATSVVVAAVVVLLFGSLFPDLIPSTLNPDWSL
MAB_2631|M.abscessus_ATCC_1997 LVAAALASRISRDGWAFACTCLTVVAVVALLFGSLYPNLIVSNLDPAYNL
MLBr_02409|M.leprae_Br4923 IAYRTTIFAFPVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAA
* .. : . :* : : :
Mb1648c|M.bovis_AF2122/97 TIHNASSTPYTLKIMTWVTAFFAPLTVAYQTWTYWVFRQRISAERIPPPT
Rv1622c|M.tuberculosis_H37Rv TIHNASSTPYTLKIMTWVTAFFAPLTVAYQTWTYWVFRQRISAERIPPPT
MMAR_2425|M.marinum_M TIYNASSTPYTLKIMTWVTALFAPLTVVYQAWTYWVFRQRISAERIPPSI
MUL_1603|M.ulcerans_Agy99 TVYNASSTPYTLKIMTWVTALFAPLTVVYQAWTYWVFRQRISAERIPPSI
MAV_3165|M.avium_104 TIYNASSTHYTLKVMTWVTAIMAPVTVVYQAWTYWVFRQRLSADRIPAPV
Mflv_3586|M.gilvum_PYR-GCK TIYNGSSTPYTLRIMTWASLALLPLVLGYQAWSYWVFRKRVTAESIPESI
Mvan_2829|M.vanbaalenii_PYR-1 TIYNGSSTPYTLRIMTWASLTLLPLVLAYQAWSYWVFRKRITAESIPASI
TH_1291|M.thermoresistible__bu TIYNGSSTPYTLQIMSWAALTLLPLVLGYQAWTYWVFRKRISTDAIPPPI
MSMEG_3232|M.smegmatis_MC2_155 TIYNGSSSPYTLKIMTWAALVFAPLVVVYQGWTYWVFSKRISADRIPAPI
MAB_2631|M.abscessus_ATCC_1997 TIVNASSSPYTLKVMSWAAAITAPVVLVYQGWTYWVFRQRISAEQIPDPV
MLBr_02409|M.leprae_Br4923 YLHARSTAGWRDRRAAWIN------VVGCVAMVFNLFFVNLVTVGLHSYA
: *:: : : :* .: : :* .: : :
Mb1648c|M.bovis_AF2122/97 GLARRAP-------------------------------------------
Rv1622c|M.tuberculosis_H37Rv GLARRAP-------------------------------------------
MMAR_2425|M.marinum_M GLARRPS-------------------------------------------
MUL_1603|M.ulcerans_Agy99 GLWLGAPPDRKGLDHPRAAGPAAVAGVGRVAVLSDRLGDLRSGHLGLCHC
MAV_3165|M.avium_104 GLTRRPS-------------------------------------------
Mflv_3586|M.gilvum_PYR-GCK GLTRRVS-------------------------------------------
Mvan_2829|M.vanbaalenii_PYR-1 GLSRRPS-------------------------------------------
TH_1291|M.thermoresistible__bu GLPR----------------------------------------------
MSMEG_3232|M.smegmatis_MC2_155 GLSRRSS-------------------------------------------
MAB_2631|M.abscessus_ATCC_1997 GLTVR---------------------------------------------
MLBr_02409|M.leprae_Br4923 GVD-----------------------------------------------
*:
Mb1648c|M.bovis_AF2122/97 --------------------------------------------------
Rv1622c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2425|M.marinum_M --------------------------------------------------
MUL_1603|M.ulcerans_Agy99 VGDRAGEHGRARRQRPLGTVSTLLAGLAVDVVGAVGVACGDALAAGAPGP
MAV_3165|M.avium_104 --------------------------------------------------
Mflv_3586|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2829|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1291|M.thermoresistible__bu --------------------------------------------------
MSMEG_3232|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2631|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02409|M.leprae_Br4923 --------------------------------------------------
Mb1648c|M.bovis_AF2122/97 --------------------------------------------------
Rv1622c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2425|M.marinum_M --------------------------------------------------
MUL_1603|M.ulcerans_Agy99 ARGQRGDRRAQWAGAGVGDGPPAQRIGGTTRCRRGGGNPRTGRLATLFHR
MAV_3165|M.avium_104 --------------------------------------------------
Mflv_3586|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2829|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1291|M.thermoresistible__bu --------------------------------------------------
MSMEG_3232|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2631|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02409|M.leprae_Br4923 --------------------------------------------------
Mb1648c|M.bovis_AF2122/97 -------------------------------------------------
Rv1622c|M.tuberculosis_H37Rv -------------------------------------------------
MMAR_2425|M.marinum_M -------------------------------------------------
MUL_1603|M.ulcerans_Agy99 LPAHAVSCGDPDPGHRGDDRGLRREVGADRGDHPSTDPGLHGLDRVGYR
MAV_3165|M.avium_104 -------------------------------------------------
Mflv_3586|M.gilvum_PYR-GCK -------------------------------------------------
Mvan_2829|M.vanbaalenii_PYR-1 -------------------------------------------------
TH_1291|M.thermoresistible__bu -------------------------------------------------
MSMEG_3232|M.smegmatis_MC2_155 -------------------------------------------------
MAB_2631|M.abscessus_ATCC_1997 -------------------------------------------------
MLBr_02409|M.leprae_Br4923 -------------------------------------------------