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NLLKLGSYGTAVPPRPDPNALTVGQVHLGLGAFHRAHQAIYTEDAMRHTGETHWAIAAFTQRSGAAATRL RPQDGLYTVTERGAAASPPRVVGALREVGDGSADPTAMVERICDPAVHVVTLTVTEKGYCLDPATGGLDF DHPRIADDLHSGAPRTVPGVLAHAIARRARSGAGPLTVISCDNLPHNGRLLQQIVHEFSDAAGLSVDDGA TVTYPSTVVDRIVPATTDEDIAALSRSIGVRDQAPVMCEPFRQWVIESRFAGPVPAWSAVGTQLVDDVAP WEQLKLRVLNAAHSTLAYLGLRLGYRSIAEAVHDSVLADICRRLFADDVRPSLDAPAGLEVGDYGESVLA RFANTALPHTTLQVASDGSQKIGPRLLRTVSARAGQGTPARWAALGIAGWALHVVDPVDADGQPTALADP RADELTAMTAGLPVGAAVRRLVTEPSIVGADVAQRRDFADYVVGVAEDLHRHGADALRAQVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2907 | - | - | 100% (483) | oxidoreductase YeiQ |
| M. smegmatis MC2 155 | MSMEG_5576 | - | 2e-65 | 31.66% (477) | D-mannonate oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0571 | - | 2e-62 | 31.98% (469) | mannitol dehydrogenase |
| M. avium 104 | MAV_1054 | - | 5e-70 | 37.44% (406) | D-mannonate oxidoreductase |
| M. thermoresistible (build 8) | TH_0045 | - | 1e-69 | 33.89% (475) | D-mannonate oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0571|M.marinum_M MKLTAANASALDIPVPNYDRSQISIGIAHFGVGGFHRAHQAMYLDRLLNA
TH_0045|M.thermoresistible__bu MKLNAANLSALSIPTPGYDRGQVRVGIVHFGVGGFHRAHQAMYLDRLLND
MAV_1054|M.avium_104 --------------------------MVHIGAGNFHRAHQAVYFDDLACS
MSMEG_2907|M.smegmatis_MC2_155 MNLLKLGSYGTAVP-PRPDPNALTVGQVHLGLGAFHRAHQAIYTEDAMRH
.*:* * *******:* :
MMAR_0571|M.marinum_M GLARDWGICGIGVLPGDERMRDALRSQDHLYTLILEHPDGTREPRVIGSI
TH_0045|M.thermoresistible__bu GLAGEWGICGVGVLPNDRRMQEALSRQDHLYTLMLAHPDGTREPRVIGSI
MAV_1054|M.avium_104 GISDQWGVSAISLRSHD--VKDLLSAQDGLYTVVQRGHD-HQTARVVGSI
MSMEG_2907|M.smegmatis_MC2_155 TGETHWAIAAFTQRSGA--AATRLRPQDGLYTVTERGAA-ASPPRVVGAL
.*.:... . * ** ***: .**:*::
MMAR_0571|M.marinum_M VDYRYAPDEPESVIELLADPAIRIISLTITEGGY----------------
TH_0045|M.thermoresistible__bu VDFRYAPDDPEGVIELLADPAVRIISLTITEGGYNLRDSDAGFDIDNPAV
MAV_1054|M.avium_104 GSVHYAPNDGAAVRAALTDPRTRIVSLTITPNGYFLDPVTREFDADHPDV
MSMEG_2907|M.smegmatis_MC2_155 REVGDGSADPTAMVERICDPAVHVVTLTVTEKGYCLDPATGGLDFDHPRI
. .. : .: : ** ::::**:* **
MMAR_0571|M.marinum_M ------TAPRSAAFELVTEALNRRRQRGHGSPAIVSCDNIVENGKVAERA
TH_0045|M.thermoresistible__bu QRDLTGDGPPATVFGLVAAGLARRRERGLPSPTIVSCDNIVENGDVARRV
MAV_1054|M.avium_104 RADLVASGCYGTAWGYLTEALEQRRRAGIAPFTVLCCDNIPDNTQAARTA
MSMEG_2907|M.smegmatis_MC2_155 ADDLH-SGAPRTVPGVLAHAIARRARSGAGPLTVISCDNLPHNGRLLQQI
. :. :: .: :* . * . :::.***: .* .
MMAR_0571|M.marinum_M FTSYADMSNPALAQWMRENTRFPNSMVDRITPVTTPELIERLDSEFGVRD
TH_0045|M.thermoresistible__bu FTSYAELADPGLAQWMREHTRFPNSMVDRITPVTTPEVIDTLATDFDVED
MAV_1054|M.avium_104 LVSFAALKNPGLARWIDRHVAFPSTMVDRITPQTSDSEREFVERTFGVAD
MSMEG_2907|M.smegmatis_MC2_155 VHEFSDAAG--LSVDDGATVTYPSTVVDRIVPATTDEDIAALSRSIGVRD
. .:: . *: . :*.::****.* *: . : :.* *
MMAR_0571|M.marinum_M AWPVAAEPFAMWVLEDDFSHGRPPLEQAGVELVDDVAPYEAMKLRLLNAG
TH_0045|M.thermoresistible__bu SWPVVAEPFCMWVLEDDFADGRPPWERAGVKLVDDVRPYEAMKLRLLNAG
MAV_1054|M.avium_104 NWPVLTEPHSQWIIEDSFSDGRPPLDEVGVQFVTDVSDHKLIKTRLLNGT
MSMEG_2907|M.smegmatis_MC2_155 QAPVMCEPFRQWVIESRFAGPVPAWSAVGTQLVDDVAPWEQLKLRVLNAA
** **. *::*. *: *. . .*.::* ** : :* *:**.
MMAR_0571|M.marinum_M HQGLCYFAYLAGYRLVHEAAQDPLIADFLCRYFDEEAAPTLTAIGGLT--
TH_0045|M.thermoresistible__bu HQSLCYFAYLSGYRLVHEAAQDPLFAEFLSRYMDSEAMPTLQPVPGLH--
MAV_1054|M.avium_104 HIALACLATLAGYRRTDEAMKDPIIFDYVERLMRDEVQPLLPPVPGMNTP
MSMEG_2907|M.smegmatis_MC2_155 HSTLAYLGLRLGYRSIAEAVHDSVLADICRRLFADDVRPSLDAPAGLEVG
* *. :. *** ** :*.:: : * : .:. * * . *:
MMAR_0571|M.marinum_M EFKNGLLPRFANAYVRDTVARLCAESSDRIPKWLLPVVRDNLRSTGPVRL
TH_0045|M.thermoresistible__bu EFKDQLIPRFANAHVRDTIARLCAESSDRIPKWLLPVIRDNLASGGPVRL
MAV_1054|M.avium_104 DYRDTLLTRLGNPRMSDQLSRLARRGSTKIASFLLPSLHEAIAQDRPHTL
MSMEG_2907|M.smegmatis_MC2_155 DYGESVLARFANTALPHTTLQVASDGSQKIGPRLLRTVSARAGQGTPARW
:: : ::.*:.*. : . ::. .* :* ** : . *
MMAR_0571|M.marinum_M SAAIVASWARYAEG-IDEAGQPIEVVDRLADTLGPIAR---SQRHDARAF
TH_0045|M.thermoresistible__bu AAATVASWARYAEG-VDEQGEPIDVVDRLADTLIPIAR---SQRDNPPAF
MAV_1054|M.avium_104 LMLALAGWARYLRG-YDLNGRKIRIDDPEADLLTKLAN---MAGNNPDPL
MSMEG_2907|M.smegmatis_MC2_155 AALGIAGWALHVVDPVDADGQPTALADPRADELTAMTAGLPVGAAVRRLV
:*.** : . * *. : * ** * :: .
MMAR_0571|M.marinum_M LANRAVFGDLIDQPRFVQPYLWALDSLHRVGARATLQALLDKDGS-----
TH_0045|M.thermoresistible__bu IENRAIFGDLVDQPRFVEAYRWALESLHRVGARATLEALLRERS------
MAV_1054|M.avium_104 LR-HEILADLRLVPGFSERLGEMVASIDEHGVIATLRQSLQDDSRELVAR
MSMEG_2907|M.smegmatis_MC2_155 TEPSIVGADVAQRRDFADYVVGVAEDLHRHGADALRAQVR----------
: .*: * : .:.. *. *