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SIFLNKDSKVIVQGITGGEGTKHTALMLKAGTQIVGGVNARKAGTTVSHKDKDGNDIELPVFGSVAEAIK ETGADVSIAFVPPAFSKDAIIEAIDAEIPLLVVITEGIPVQDTAYAWAYNVDKGQKTRIIGPNCPGIITP GEALVGITPNNITGKGPIGLVSKSGTLTYQMMYELRDFGFSTAIGIGGDPVIGTTHIDAIEAFEKDPETK VIVMIGEIGGDAEERAADYIKANVTKPVVGYVAGFTAPEGKTMGHAGAIVSGSSGTAAAKKEALEAAGVK VGKTPSETAKLAREILQSL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5524 | sucD | - | 100% (300) | succinyl-CoA synthetase subunit alpha |
| M. smegmatis MC2 155 | MSMEG_4075 | - | 2e-07 | 28.17% (252) | CoA-binding protein |
| M. smegmatis MC2 155 | MSMEG_0666 | - | 4e-05 | 28.67% (150) | acetyl-CoA synthetase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0977 | sucD | 1e-147 | 86.33% (300) | succinyl-CoA synthetase subunit alpha |
| M. gilvum PYR-GCK | Mflv_1866 | - | 1e-157 | 92.00% (300) | succinyl-CoA synthetase subunit alpha |
| M. tuberculosis H37Rv | Rv0952 | sucD | 1e-146 | 86.00% (300) | succinyl-CoA synthetase subunit alpha |
| M. leprae Br4923 | MLBr_00156 | sucD | 1e-144 | 84.00% (300) | succinyl-CoA synthetase subunit alpha |
| M. abscessus ATCC 19977 | MAB_1057 | - | 1e-162 | 95.00% (300) | succinyl-CoA synthetase subunit alpha |
| M. marinum M | MMAR_4549 | sucD | 1e-150 | 88.00% (300) | succinyl-CoA synthetase (alpha chain) SucD |
| M. avium 104 | MAV_1075 | - | 1e-157 | 91.00% (300) | succinyl-CoA synthetase subunit alpha |
| M. thermoresistible (build 8) | TH_1772 | sucD | 1e-156 | 91.33% (300) | PROBABLE SUCCINYL-CoA SYNTHETASE (ALPHA CHAIN) SUCD |
| M. ulcerans Agy99 | MUL_4719 | sucD | 1e-149 | 87.67% (300) | succinyl-CoA synthetase subunit alpha |
| M. vanbaalenii PYR-1 | Mvan_4869 | - | 1e-163 | 95.67% (300) | succinyl-CoA synthetase subunit alpha |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0977|M.bovis_AF2122/97 MTHMSIFLSRDNKVIVQGITGSEATVHTARMLRAGTQIVGGVNARKAGTT
Rv0952|M.tuberculosis_H37Rv MTHMSIFLSRDNKVIVQGITGSEATVHTARMLRAGTQIVGGVNARKAGTT
MMAR_4549|M.marinum_M ---MSIFLNKDNKVIVQGITGSEATVHTARMLKAGTQIVGGVNARKAGTT
MUL_4719|M.ulcerans_Agy99 ---MSIFLNKDNKVIVQGITGSEATVHTARMLKAGTQIVGGVNARKAGTT
Mflv_1866|M.gilvum_PYR-GCK ---MSIFLNADSKVIVQGITGGEGTKHTKLMLKAGTQIVGGVNARKAGTE
Mvan_4869|M.vanbaalenii_PYR-1 ---MSIFLNKDSKVIVQGITGGEGTKHTKLMLKAGTQIVGGVNARKAGTT
MSMEG_5524|M.smegmatis_MC2_155 ---MSIFLNKDSKVIVQGITGGEGTKHTALMLKAGTQIVGGVNARKAGTT
MAB_1057|M.abscessus_ATCC_1997 ---MSIFLNKDSKVIVQGITGGEGTKHTALMLKAGTQVVGGVNARKAGTT
MAV_1075|M.avium_104 ---MSIFLNKDSKVIVQGITGGEGTKHTALMLKAGTQVVGGVNARKAGTT
TH_1772|M.thermoresistible__bu ---MSIFLNKNSKVIVQGITGGEGTKHTALMLKAGTQIVGGVNARKAGTT
MLBr_00156|M.leprae_Br4923 ---MAIFLTKDNTVIVQGITGSEAAVHTARMLKAGTQIVGGVNARKAGTN
*:***. :..********.*.: ** **:****:***********
Mb0977|M.bovis_AF2122/97 VTHEDKGGRLIKLPVFGSVAEAMEKTGADVSIIFVPPTFAKDAIIEAIDA
Rv0952|M.tuberculosis_H37Rv VTHEDKGGRLIKLPVFGSVAEAMEKTGADVSIIFVPPTFAKDAIIEAIDA
MMAR_4549|M.marinum_M VTHEDKGGRVIKLPVFGGVAEAMEKTGADVSIIFVPPKFAKDAIIEAIDA
MUL_4719|M.ulcerans_Agy99 VTHEDKGGRVIKLPVFGGVAEAMEKTGADVSIIFVPPKFAKDAIIEAIDA
Mflv_1866|M.gilvum_PYR-GCK VTHQDKDGKDVNLPVFGSVAEAMKETGADVSIAFVPPAFSKDAIIEAIDA
Mvan_4869|M.vanbaalenii_PYR-1 VKHEDKDGNEVELPVFASVAEAMKETGADVSIAFVPPAFSKDAIIEAIDA
MSMEG_5524|M.smegmatis_MC2_155 VSHKDKDGNDIELPVFGSVAEAIKETGADVSIAFVPPAFSKDAIIEAIDA
MAB_1057|M.abscessus_ATCC_1997 VSHVDKSGQSVDLPVFGSVAEAIKETGADVSIAFVPPAFSKDAIIEAIDA
MAV_1075|M.avium_104 VSHVDPVGKDVELPVFGTVSEAMKETGANVSVVFVPPKFAKDAIIEAIDA
TH_1772|M.thermoresistible__bu VSHTDKDGKDVELPVFGTVEEAMKETGADVSVVFVPPKFAKDAIIEAIDA
MLBr_00156|M.leprae_Br4923 VTHEDKHGRIITLPVFGTVAEAIENTGADVSIIFVPPRFAKEAIIEAVEA
*.* * *. : ****. * **:::***:**: **** *:*:*****::*
Mb0977|M.bovis_AF2122/97 EIPLLVVITEGIPVQDTAYAWAYNLEAGHKTRIIGPNCPGIISPGQSLAG
Rv0952|M.tuberculosis_H37Rv EIPLLVVITEGIPVQDTAYAWAYNLEAGHKTRIIGPNCPGIISPGQSLAG
MMAR_4549|M.marinum_M EIPLLVVITEGIPVQDTAYAWAYNLGKGGKTRIIGPNCPGIITPGQALVG
MUL_4719|M.ulcerans_Agy99 EIPLLVVITEVIPVQDTAYAWAYNLGKGGKTRIIGPNCPGIITPGQALVG
Mflv_1866|M.gilvum_PYR-GCK EIPLLVVITEGIPVQDTAYAWAYNVEKGEKTRIIGPNCPGIITPGESLVG
Mvan_4869|M.vanbaalenii_PYR-1 EIPLLVVITEGIPVQDTAYAWAYNVDKGQKTRIIGPNCPGIITPGESLVG
MSMEG_5524|M.smegmatis_MC2_155 EIPLLVVITEGIPVQDTAYAWAYNVDKGQKTRIIGPNCPGIITPGEALVG
MAB_1057|M.abscessus_ATCC_1997 EIPLLVVITEGIPVQDSAYAWAYNVEKGNKTRIIGPNCPGIITPGEALVG
MAV_1075|M.avium_104 EIPLLVVITEGIPVQDSAYAWAYNVDKGQKTRIIGPNCPGIITPGEALAG
TH_1772|M.thermoresistible__bu EIALLVVITEGIPVQDTAYAWAYNVKRGQKTRIIGPNCPGIITPGEALAG
MLBr_00156|M.leprae_Br4923 EIPLLVIITEGIPVQDSVYAWAYNLNKGTKTRIIGPNCPGIITPGQSLVG
**.***:*** *****:.******: * *************:**::*.*
Mb0977|M.bovis_AF2122/97 ITPANITGPGPIGLVSKSGTLTYQMMFELRDLGFSTAIGIGGDPVIGTTH
Rv0952|M.tuberculosis_H37Rv ITPANITGPGPIGLVSKSGTLTYQMMFELRDLGFSTAIGIGGDPVIGTTH
MMAR_4549|M.marinum_M ITPANITGAGPVGLVSKSGTLTYQMMFELRDFGFTTSIGIGGDPVIGTTH
MUL_4719|M.ulcerans_Agy99 ITPANITGAGPVGLVSKSGTLTYQMMFELRDFGFTTSIGIGGDPVIGTTH
Mflv_1866|M.gilvum_PYR-GCK ITPNNITGKGPIGLVSKSGTLTYQMMYELRDLGFSTAIGIGGDPVIGTTH
Mvan_4869|M.vanbaalenii_PYR-1 ITPNNITGKGPIGLVSKSGTLTYQMMYELRDLGFSTAIGIGGDPVIGTTH
MSMEG_5524|M.smegmatis_MC2_155 ITPNNITGKGPIGLVSKSGTLTYQMMYELRDFGFSTAIGIGGDPVIGTTH
MAB_1057|M.abscessus_ATCC_1997 ITPNNITGTGPVGLVSKSGTLTYQMMYELRDFGFSTAIGIGGDPVIGTTH
MAV_1075|M.avium_104 ITPANISGPGPVGLVSKSGTLTYQMMYELRDFGFSTSIGIGGDPIIGTTH
TH_1772|M.thermoresistible__bu ITPANITGPGPIGLVSKSGTLTYQMMFELSDFGFSTAIGIGGDPIIGTTH
MLBr_00156|M.leprae_Br4923 ITPATITGAGPIGLVSKSGTLTYQMMFELSDFGFSTAIGIGGDPVIGTTH
*** .*:* **:**************:** *:**:*:*******:*****
Mb0977|M.bovis_AF2122/97 IDAIEAFEKDPDTKLIVMIGEIGGDAEERAADFIKTNVSKPVVGYVAGFT
Rv0952|M.tuberculosis_H37Rv IDAIEAFERDPDTKLIVMIGEIGGDAEERAADFIKTNVSKPVVGYVAGFT
MMAR_4549|M.marinum_M IDAIEAFEKDPDTKLIVMIGEIGGDAEERAADFIKANVSKPVVGYVAGFT
MUL_4719|M.ulcerans_Agy99 IDAIEAFEKDPDTKLIVMIGEIGGDAEERAADFIKANVSKPVVGYVAGFT
Mflv_1866|M.gilvum_PYR-GCK IDAIEAFEKDPETKLIVMIGEIGGDAEEKAADYIKANVTKPVVGYVAGFT
Mvan_4869|M.vanbaalenii_PYR-1 IDAIEAFEKDPETKIIVMIGEIGGDAEERAADYIKANVSKPVVGYVAGFT
MSMEG_5524|M.smegmatis_MC2_155 IDAIEAFEKDPETKVIVMIGEIGGDAEERAADYIKANVTKPVVGYVAGFT
MAB_1057|M.abscessus_ATCC_1997 IDAIEAFEKDPETKIIVMIGEIGGDAEERAADYIKANVSKPVVGYVAGFT
MAV_1075|M.avium_104 IDAIEAFEKDPDTKIIVMIGEIGGDAEERAADYIKAHVSKPVVGYVAGFT
TH_1772|M.thermoresistible__bu IDAIEAFEKDPDTKLIVMIGEIGGDAEERAAEYIKANVSKPVVGYVAGFT
MLBr_00156|M.leprae_Br4923 IDAIEAFEQDPDTKIIVMIGEIGGDAEERAADYIKANVSKPVVGYVAGFT
********:**:**:*************:**::**::*:***********
Mb0977|M.bovis_AF2122/97 APEGKTMGHAGAIVSGSSGTAAAKQEALEAAGVKVGKTPSATAALAREIL
Rv0952|M.tuberculosis_H37Rv APEGKTMGHAGAIVSGSSGTAAAKQEALEAAGVKVGKTPSATAALAREIL
MMAR_4549|M.marinum_M APEGKTMGHAGAIVSGSSGTAAAKKEALEAAGVQVGKTPSETAMLAREIL
MUL_4719|M.ulcerans_Agy99 APEGKTMGHAGAIVSGSSGTAAAKKEALEAAGVQVGKTPSETAVLAREIL
Mflv_1866|M.gilvum_PYR-GCK APEGKTMGHAGAIVSDGAGTAAGKQEALEAAGVKVGKTPSETAAKARELL
Mvan_4869|M.vanbaalenii_PYR-1 APEGKTMGHAGAIVSGSSGTAAAKKEALEAAGVKVGKTPSETAKLAREIL
MSMEG_5524|M.smegmatis_MC2_155 APEGKTMGHAGAIVSGSSGTAAAKKEALEAAGVKVGKTPSETAKLAREIL
MAB_1057|M.abscessus_ATCC_1997 APEGKTMGHAGAIVSGSSGTAQAKKEALEAAGVKVGKTPSETAKLAREIL
MAV_1075|M.avium_104 APEGKTMGHAGAIVSGSSGTAAAKKEALEAAGVKVGKTPSETAALAREIL
TH_1772|M.thermoresistible__bu APEGKTMGHAGAIVSGSSGTAQAKKEALEAAGVKVGKTPSETARLAREIL
MLBr_00156|M.leprae_Br4923 APEGKTMGHAGAIVSGSSGTAAVKKDALEAAGVKVGKTPSETAVLVREIL
***************..:*** *::*******:****** ** .**:*
Mb0977|M.bovis_AF2122/97 LSL
Rv0952|M.tuberculosis_H37Rv LSL
MMAR_4549|M.marinum_M KGL
MUL_4719|M.ulcerans_Agy99 KGL
Mflv_1866|M.gilvum_PYR-GCK QNL
Mvan_4869|M.vanbaalenii_PYR-1 AGL
MSMEG_5524|M.smegmatis_MC2_155 QSL
MAB_1057|M.abscessus_ATCC_1997 QSL
MAV_1075|M.avium_104 QSL
TH_1772|M.thermoresistible__bu QSL
MLBr_00156|M.leprae_Br4923 CTL
*