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M. smegmatis MC2 155 MSMEG_0666 (-)

annotation: acetyl-CoA synthetase, putative
coordinates: 747619 - 749646
length: 675

VATMLGARSMAVIGASARAGSFGERMVIEARRGSARTHLVNPRYRRIGDLPCHASLDDLDEVPDLVLLGV
PDDALIDQLQAAAAAGVRSAVLFGSAHGAGMRRAITDIATRAGMALCGAGCMGFVNTVTGVRALGYLEPD
PLPAGGVSLVTHSGSAFSTLLRARRGFGFRLAVSSGQELVTDTADYVEYALDDPGTQVIGLLLETPRAAP
RLRNVLRQAAERDVPVVILTVGGSPRGRAMVAAHSGALAGDAAGWAAFCASTGAVRTTDLTEFTDTLELF
ACEARAGRLQRRGGGRGIATVHDSGAERALCADVAHEMGVEFAELSPRTLGVIGDLLDDGLTPSNPLDMW
GTGADTRTVFGGCLRAMVEDPAVAVTALAVDLVTEYDGDTAYTDAVLDVEGQAPLAVLASVPSAIDPVMA
QRLRDRGVAVLEGMRSGLAAMGHLAAWPLPVDTEPVVVDQVRRDRWSRATGPAFDLLADYGVAVPDSRPA
HSRAEAVAAAAAIGYPVAVKTAGAAHKSDVGGVVLGVSGPDEVVAVYDDMAARLGPAVSVDAMVPAGVEV
SVGFVRDAAFGPLVVVAAGGVAVELHGDRVVVCPPVSRTTARRIVDQLRIAPLLTGWRGGPVADIDALVD
VIVAFSAMAVELGDMLDAVEANPVIVSATGAVAVDALVVPNSVPG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0666--100% (675)acetyl-CoA synthetase, putative
M. smegmatis MC2 155MSMEG_4075-7e-6429.06% (702) CoA-binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1419carB9e-0627.66% (235) carbamoyl phosphate synthase large subunit
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv1384carB3e-0527.66% (235) carbamoyl phosphate synthase large subunit
M. leprae Br4923MLBr_00156sucD4e-0528.00% (150) succinyl-CoA synthetase subunit alpha
M. abscessus ATCC 19977MAB_2827ccarB2e-0528.39% (236) carbamoyl phosphate synthase large subunit
M. marinum MMMAR_2406-1e-0535.37% (82) Mur family ligase
M. avium 104MAV_3389carB9e-0525.55% (274) carbamoyl phosphate synthase large subunit
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2920fadD312e-0625.72% (311) acyl-CoA synthetase
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb1419|M.bovis_AF2122/97            MPRRTDLHHVLVIGSGPIVIGQACEFDYSGTQACRVLRAEGLQVSLVNSN
Rv1384|M.tuberculosis_H37Rv         MPRRTDLHHVLVIGSGPIVIGQACEFDYSGTQACRVLRAEGLQVSLVNSN
MAV_3389|M.avium_104                MPRRTDLNHVLVIGSGPIVIGQACEFDYSGTQACRVLKAEGLQVSLVNSN
MAB_2827c|M.abscessus_ATCC_199      MPRRTDLNHILVIGSGPIVIGQACEFDYSGTQACRVLRSEGLQVSLVNSN
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      -------MATMLGARSMAVIGASARAGSFGERMVIEARRGSARTHLVNPR
MUL_2920|M.ulcerans_Agy99           -------MNDGSRQDSAAPKGLLEIEDCLDAGGNIELPPGTTLISLIERN
MMAR_2406|M.marinum_M               -----MNIDSISVYVGPNVHALEAVIRLQVDVKPSYAETLRGLGAGVIDR
                                                                                      

Mb1419|M.bovis_AF2122/97            PATIMTDPEFADHTYVEPITPAFVERVIAQQAERGNKIDALLATLGGQTA
Rv1384|M.tuberculosis_H37Rv         PATIMTDPEFADHTYVEPITPAFVERVIAQQAERGNKIDALLATLGGQTA
MAV_3389|M.avium_104                PATIMTDPEYADHTYVEPITPAFVERVIAQQAERGNKIDALLATLGGQTA
MAB_2827c|M.abscessus_ATCC_199      PATIMTDPEYADNTYVEPITAEFVEKVIAAQAEKGNKIDALLPTLGGQTA
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      YRRIGDLPCHASLDDLDEVP------------------------------
MUL_2920|M.ulcerans_Agy99           IANVGDSVAYRYLDHNRTAQG-----------------------------
MMAR_2406|M.marinum_M               LAAVLPGLALEHAEWVAALHAG----------------------------
                                                                                      

Mb1419|M.bovis_AF2122/97            LNTAVALYESGVLEKYGVELIGADFDAIQRGEDRQRFKDIVAKAGGESAR
Rv1384|M.tuberculosis_H37Rv         LNTAVALYESGVLEKYGVELIGADFDAIQRGEDRQRFKDIVAKAGGESAR
MAV_3389|M.avium_104                LNTAVALYENGALDRYGVELIGADFDAIQRGEDRQRFKDIVAKVGGESAR
MAB_2827c|M.abscessus_ATCC_199      LNTAVALYENGALDRYGVELIGANFEAIQRGEDRQRFKDIVAKVGGESAK
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      -------------------------DLVLLGVPDDALIDQLQAAAAAGVR
MUL_2920|M.ulcerans_Agy99           --------------------HALEVTWSEFGVRLQAIGAHVQKFAGDGDR
MMAR_2406|M.marinum_M               -------------------------AGLSIGDLVARLALALEHAAGIDGT
                                                                                      

Mb1419|M.bovis_AF2122/97            SRVCFTMAEVRETVAELGLPVVVRPSFTMGGLGSGIAYSTDEVDRMAGAG
Rv1384|M.tuberculosis_H37Rv         SRVCFTMAEVRETVAELGLPVVVRPSFTMGGLGSGIAYSTDEVDRMAGAG
MAV_3389|M.avium_104                SRVCFTMDEVRETVAELGLPVVVRPSFTMGGLGSGMARSVEEVDRMAGAG
MAB_2827c|M.abscessus_ATCC_199      SRVCFTMEEVRETVADLGLPVVVRPSFTMGGLGSGMAYTADDVERMAGEG
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      SAVLFGSAHG-----------------------AGMRRAITDIATRAGMA
MUL_2920|M.ulcerans_Agy99           VAILAP-------------------------------QGIDYVAGFYAAI
MMAR_2406|M.marinum_M               LAWSRSTDDPD----------IVEVFYSYGNEDIGIEAGEVACDMLAAIA
                                                                                      

Mb1419|M.bovis_AF2122/97            LAASPSANVLIEESIYGWKEFELELMRDGHDNVVVVCSIENVDPMGVHTG
Rv1384|M.tuberculosis_H37Rv         LAASPSANVLIEESIYGWKEFELELMRDGHDNVVVVCSIENVDPMGVHTG
MAV_3389|M.avium_104                LAESPSANVLIEESIYGWKEFELELMRDGNDNVVVVCSIENVDPMGVHTG
MAB_2827c|M.abscessus_ATCC_199      LSASPSANVLIEESIYGWKEFELELMRDGRDNVVVVCSIENVDPMGVHTG
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      LCGAG--------------------------CMGFVNTVTGVRALGYLEP
MUL_2920|M.ulcerans_Agy99           KAG------------------------------TIAVPLFAPELPGHAER
MMAR_2406|M.marinum_M               RADSDDQEAPDLDKNVEDFLTYADRRSLGPSAMELVRTAQARDIPVYRLN
                                                                                      

Mb1419|M.bovis_AF2122/97            DSVTVAPAMTLTDREYQRMRDLGIAILREVGVDTGGCNIQFAVNPRDGRL
Rv1384|M.tuberculosis_H37Rv         DSVTVAPAMTLTDREYQRMRDLGIAILREVGVDTGGCNIQFAVNPRDGRL
MAV_3389|M.avium_104                DSVTVAPAMTLTDREYQRMRDLGIAILREVGVDTGGCNIQFAVNPKDGRL
MAB_2827c|M.abscessus_ATCC_199      DSVTVAPAMTLTDREYQKMRDLGIAILREVGVDTGGCNIQFAINPRDGRL
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      DPLPAG------------------------------------------GV
MUL_2920|M.ulcerans_Agy99           -----------------------------------------------LDT
MMAR_2406|M.marinum_M               DASLIQIGQG---------------------------------KYQQRIE
                                                                                      

Mb1419|M.bovis_AF2122/97            IVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEIVNDITGETPA
Rv1384|M.tuberculosis_H37Rv         IVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEIVNDITGETPA
MAV_3389|M.avium_104                IVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEIVNDITKETPA
MAB_2827c|M.abscessus_ATCC_199      IVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEIVNDITKETPA
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      SLVTHSGSAFSTLLRARRGFGFRLAVSSGQELVTDTADYVEYALDDPGTQ
MUL_2920|M.ulcerans_Agy99           ALRDSEPTVVLTTGAAKPAIEEFLANLSHLRRPHIITIDDVPDSAGESFV
MMAR_2406|M.marinum_M               AALTSKTSHIAVEIASDKNLANNLLADLGLPAPRQKLVYSVDEAVGAAER
                                                                                      

Mb1419|M.bovis_AF2122/97            CFEPTLDYVVVKAPRFAFEKFPGADPTLTTTMKSVGEAMSLGRNFVEALG
Rv1384|M.tuberculosis_H37Rv         CFEPTLDYVVVKAPRFAFEKFPGADPTLTTTMKSVGEAMSLGRNFVEALG
MAV_3389|M.avium_104                CFEPTLDYVVVKAPRFAFEKFPGADPTLTTTMKSVGEAMSLGRNFIEALG
MAB_2827c|M.abscessus_ATCC_199      CFEPTLDYVVVKAPRFAFEKFPGADATLTTTMKSVGEAMSLGRNFAEALG
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      VIG-------------LLLETPRAAPRLRNVLRQAAERDVPVVILTVGGS
MUL_2920|M.ulcerans_Agy99           PVELDIDAVSHLQYTSGSTRPPVGVEITHRAVGTNLVQMILSIDLLNRNT
MMAR_2406|M.marinum_M               IGYPVVIKPLDGNHGRGVTVNITSEDGIAEAFETADAEGSAVLVETMLRG
                                                                                      

Mb1419|M.bovis_AF2122/97            KVMRSLETTRAGFWT-APDPDGGIEEALTRLRTPAEGRLYDIELALRLGA
Rv1384|M.tuberculosis_H37Rv         KVMRSLETTRAGFWT-APDPDGGIEEALTRLRTPAEGRLYDIELALRLGA
MAV_3389|M.avium_104                KVMRSLETSRAGFWT-KPDPDGGLDDVLARLQTPTEGRLYDLELALRLGA
MAB_2827c|M.abscessus_ATCC_199      KVMRSLETSAAGFWTDKAEPIEDLDAFLKELRVPRDGRLYGIERALAAGV
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      PRGRAMVAAHSGALAGDAAGWAAFCASTGAVRTTDLTEFTDTLELFACEA
MUL_2920|M.ulcerans_Agy99           HGVSWLPLYHDMGLSMIGFPAVYGGHSTLMSPTAFVRRPQRWIHALSAGS
MMAR_2406|M.marinum_M               DDHRLLVVNGQLAAAARRVPGHVKGDGRHTIAELVNIVNQDPRRGVGHEN
                                                                                      

Mb1419|M.bovis_AF2122/97            TVERVAEASGVDPWFIAQINELVNLRNELVAAPVLNAELLRRAKHSGLSD
Rv1384|M.tuberculosis_H37Rv         TVERVAEASGVDPWFIAQINELVNLRNELVAAPVLNAELLRRAKHSGLSD
MAV_3389|M.avium_104                PVERVAQASGVDPWFIAQIGELVALRGELIGAPVLDADLLRRAKHHGLSD
MAB_2827c|M.abscessus_ATCC_199      PVEQVAEVTGVDPWFVEEIAQINQLGTELREAPILDEELLRRAKHYGLSD
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      RAGRLQRRG-----------------------------------------
MUL_2920|M.ulcerans_Agy99           RTG-----------------------------------------------
MMAR_2406|M.marinum_M               VLTRLELDDQATRLLEEKGYTAETVPAEGEEVYLRKTANISTGGTAVDVT
                                                                                      

Mb1419|M.bovis_AF2122/97            HQIASLRPELAGEAGVRSLRVRLGIHPVYKTVDTCAAEFEAQTPYHYSSY
Rv1384|M.tuberculosis_H37Rv         HQIASLRPELAGEAGVRSLRVRLGIHPVYKTVDTCAAEFEAQTPYHYSSY
MAV_3389|M.avium_104                RQIAALRPELAGENGVRSLRERLGVHPVYKTVDTCAAEFEAKTPYHYSSY
MAB_2827c|M.abscessus_ATCC_199      RQIAALRPELAGENGVRSLRHRMGIRPVYKTVDTCAAEFEAKTPYHYSSY
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      -----------GGRGIATVHDSG---------------------------
MUL_2920|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2406|M.marinum_M               DTIHPDNKLMAERAIRAIGLDVG-------------------------AV
                                                                                      

Mb1419|M.bovis_AF2122/97            ELDPAAETEVAPQTERPKVLILGSGPNRIGQGIEFDYSCVHAATTLSQAG
Rv1384|M.tuberculosis_H37Rv         ELDPAAETEVAPQTERPKVLILGSGPNRIGQGIEFDYSCVHAATTLSQAG
MAV_3389|M.avium_104                ELDPAAETEVAPQPQRPKVLILGSGPNRIGQGIEFDYSCVHAATTLSQAG
MAB_2827c|M.abscessus_ATCC_199      ELDPAAESEVAPQTERPKVLILGSGPNRIGQGIEFDYSCVHAATTLSQAG
MLBr_00156|M.leprae_Br4923          -----------------MAIFLTKDNTVIVQGITGSEAAVHTARMLKAGT
MSMEG_0666|M.smegmatis_MC2_155      -AERALCADVAHEMGVEFAELSPRTLGVIGDLLDDGLTPSNPLDMWGTGA
MUL_2920|M.ulcerans_Agy99           -RVVTAAPNFAYEWAAQRGLLTPGDDVDLSNVVLIIGSEPVSIDAVTTFN
MMAR_2406|M.marinum_M               DFLTTDITKSYRETGGGICEINAGPGLRMHIAPSEGTPRDVGGAIMDMLF
                                                        :       :        .            

Mb1419|M.bovis_AF2122/97            FETVMVNCNPETVSTDYDTADRLYFEPLTFEDVLEVYHAEMESGSGGPGV
Rv1384|M.tuberculosis_H37Rv         FETVMVNCNPETVSTDYDTADRLYFEPLTFEDVLEVYHAEMESGSGGPGV
MAV_3389|M.avium_104                FETVMVNCNPETVSTDYDTADRLYFEPLTFEDVLEVFRAEQQSGAGGPGV
MAB_2827c|M.abscessus_ATCC_199      FETIMVNCNPETVSTDYDTADRLYFEPLTFEDVLEVYHAESESGRGGPGV
MLBr_00156|M.leprae_Br4923          QIVGGVNARKAGTNVTHEDKHGRIITLPVFGTVAEAIEN--------TGA
MSMEG_0666|M.smegmatis_MC2_155      DTRTVFGGCLRAMVEDPAVAVTALAVDLVTEYDGDTAYTDAVLDVEGQAP
MUL_2920|M.ulcerans_Agy99           KVFAPYGLPRAAFKPSYGIAEATLLVATIDHAAEPTVVYLDREQLGAGHA
MMAR_2406|M.marinum_M               PPGTQARVPIAALTGTNGKTTCSRMLAHILKMAGHVVGQTSTDAVLIDGN
                                                                       .              

Mb1419|M.bovis_AF2122/97            AGVIVQLGGQTPLGLAHRLADAGVPIVGTPPEAIDLAEDRGAFGDLLSAA
Rv1384|M.tuberculosis_H37Rv         AGVIVQLGGQTPLGLAHRLADAGVPIVGTPPEAIDLAEDRGAFGDLLSAA
MAV_3389|M.avium_104                VGVIVQLGGQTPLGLAQRLADAGVPIVGTPPEAIDLAEDRGSFGDVLTAA
MAB_2827c|M.abscessus_ATCC_199      VGVIVQLGGQTPLGLAKRLADAGVPVVGTSPAAIDRAEDRGVFGDLLVSA
MLBr_00156|M.leprae_Br4923          DVSIIFVPPRFAKEAIIEAVEAEIPLLVIITEGIPVQDSVYAWAYNLNKG
MSMEG_0666|M.smegmatis_MC2_155      LAVLASVPSAIDPVMAQRLRDRGVAVLEGMRSGLAAMGHLAAWPLPVDTE
MUL_2920|M.ulcerans_Agy99           VRVAAEAPNAVLQVSCGRVAHSLWAVIVDPDTGTELRDGEVGEIWLQGNN
MMAR_2406|M.marinum_M               VTVKGDMTGPVSAKMVLRDPSVDIAVLETARGGIVRSGLGYNFCDVGAVL
                                                     .      .::     .                 

Mb1419|M.bovis_AF2122/97            GLPAPKYGTATTFAQARRIAEEIGYPVLVRPSYVLGGRGMEIVYDEETLQ
Rv1384|M.tuberculosis_H37Rv         GLPAPKYGTATTFAQARRIAEEIGYPVLVRPSYVLGGRGMEIVYDEETLQ
MAV_3389|M.avium_104                GLPAPKYGTATTFAQARRIAVDIGYPVLVRPSYVLGGRGMEIVYDEETLR
MAB_2827c|M.abscessus_ATCC_199      GLPAPRFGTATTFEQAKQIAADIGYPVLVRPSYVLGGRGMEIVYDEETLH
MLBr_00156|M.leprae_Br4923          --------------------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      PVVVDQVRRD----------------------------------------
MUL_2920|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2406|M.marinum_M               NVASDHLGLGGVDTLDDLARVKRVVAEVTRGTVVLNADDEQTLKMAAFSP
                                                                                      

Mb1419|M.bovis_AF2122/97            GYITRATQLSPEHPVLVDRFLEDAVEIDVDALCDGAEVYIGG------IM
Rv1384|M.tuberculosis_H37Rv         GYITRATQLSPEHPVLVDRFLEDAVEIDVDALCDGAEVYIGG------IM
MAV_3389|M.avium_104                DYITRATELSPEHPVLVDRFLEDAVEIDVDALCDGTEVYIGG------IM
MAB_2827c|M.abscessus_ATCC_199      GYIARATQLSPEHPVLVDRFLEDAIEIDVDALCDGTEVYLGG------VM
MLBr_00156|M.leprae_Br4923          ---TKTRIIGPNCPGIIT--------------------------------
MSMEG_0666|M.smegmatis_MC2_155      ---RWSRATGPAFDLLADYG------------------------------
MUL_2920|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2406|M.marinum_M               ARQVMYVTRNPEHELVREHIRLGKLAVVLEQGVNGDQIVIYDNGTQMPLM
                                                                                      

Mb1419|M.bovis_AF2122/97            EHIEEAGIHSGDSACALPPVTLGRSDIEKVRKATEAIAHGIGVVGLLNVQ
Rv1384|M.tuberculosis_H37Rv         EHIEEAGIHSGDSACALPPVTLGRSDIAKVRKATEAIAHGIGVVGLLNVQ
MAV_3389|M.avium_104                EHIEEAGIHSGDSACALPPVTLGRSDIEKVRRATEAIAHGIGVVGLLNVQ
MAB_2827c|M.abscessus_ATCC_199      EHIEEAGIHSGDSACALPPVTLGRSDIEKVRKATEAIAHGIGVVGLLNVQ
MLBr_00156|M.leprae_Br4923          ---------PGQSLVGITPATIT----------------GAGPIGLVSKS
MSMEG_0666|M.smegmatis_MC2_155      -----VAVPDSRPAHSRAEAVAAAAAIGYPVAVKTAGAAHKSDVGGVVLG
MUL_2920|M.ulcerans_Agy99           ---------VGRGYWGWPEDTERVFGAKLHSQLDEASHAAGAAVDGAWLR
MMAR_2406|M.marinum_M               WTQLIPATLEGKALHNVENAMFATGMAYALGKTLDQISAGLRTFDNSFFQ
                                              .                                ..     

Mb1419|M.bovis_AF2122/97            YALKDDVLYVLEANPRASRTVPFVSKATAVPLAKACARIMLGATIAQLRA
Rv1384|M.tuberculosis_H37Rv         YALKDDVLYVLEANPRASRTVPFVSKATAVPLAKACARIMLGATIAQLRA
MAV_3389|M.avium_104                YALKDDVLYVLEANPRASRTVPFVSKATAIPLAKACARIMLGATISQLRA
MAB_2827c|M.abscessus_ATCC_199      YALKDDVLYVLEANPRASRTVPFVSKATAVPLAKACARIMLGATIAGLRE
MLBr_00156|M.leprae_Br4923          GTLTYQMMFELSD-------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      VSGPDEVVAVYDD-------------------------------------
MUL_2920|M.ulcerans_Agy99           TG---DLGVYLDG-------------------------------------
MMAR_2406|M.marinum_M               SPGRMNVFDEHGFRVILDYG------------------------------
                                         ::                                           

Mb1419|M.bovis_AF2122/97            EGLLAVTGDGAHAARNAPIAVKEAVLPFHRFRRADGAAIDSLLGPEMKST
Rv1384|M.tuberculosis_H37Rv         EGLLAVTGDGAHAARNAPIAVKEAVLPFHRFRRADGAAIDSLLGPEMKST
MAV_3389|M.avium_104                EEMLAASGDGAHAALNAPIAVKEAVLPFHRFRTVEGAGIDSLLGPEMKST
MAB_2827c|M.abscessus_ATCC_199      EGLLPAEGDGATSLPGAPVAVKEAVLPFHRFRKADGSGVDSLLGPEMKST
MLBr_00156|M.leprae_Br4923          ----------------------------FGFSTAIGIGGDPVIGTTHIDA
MSMEG_0666|M.smegmatis_MC2_155      ----------------------------MAARLGPAVSVDAMV-PAGVEV
MUL_2920|M.ulcerans_Agy99           ------------------------------ELYVTGRIADLIVIDGHNHY
MMAR_2406|M.marinum_M               ----------------HNEAAVGAMVDLVDRLKPRGRRIVGLTCPGDRRD
                                                                       .     :        

Mb1419|M.bovis_AF2122/97            GEVMGIDRDFGSAFAKSQTAAYGSLPAQGTVFVSVANRDKRSLVFPVKRL
Rv1384|M.tuberculosis_H37Rv         GEVMGIDRDFGSAFAKSQTAAYGSLPAQGTVFVSVANRDKRSLVFPVKRL
MAV_3389|M.avium_104                GEVMGIDRDFGSAFAKSQTAAYGSLPAQGTVFVSVANRDKRSLVFPVKRL
MAB_2827c|M.abscessus_ATCC_199      GEVMGIDADFGSAFAKSQTAAYGSLPKEGTIFVSVANRDKRSLVFPVKRL
MLBr_00156|M.leprae_Br4923          IEAFEQDPDT----------------------------------------
MSMEG_0666|M.smegmatis_MC2_155      SVGFVRDAAFG---------------------------------------
MUL_2920|M.ulcerans_Agy99           PQDIEATVAEAS--------------------------------------
MMAR_2406|M.marinum_M               EDATAIAAKVAG--------------------------------------
                                                                                      

Mb1419|M.bovis_AF2122/97            ADLGFRVLATEGTAEMLRRNGIPCDDVRKHFEPAQPGRPTMSAVDAIRAG
Rv1384|M.tuberculosis_H37Rv         ADLGFRVLATEGTAEMLRRNGIPCDDVRKHFEPAQPGRPTMSAVDAIRAG
MAV_3389|M.avium_104                ADLGFRVLATEGTAEMLRRNGIPCDEVRKHFEDPQPGRPEMSAVDAIKAG
MAB_2827c|M.abscessus_ATCC_199      ADLGFTVLATEGTAEMLRRNGIPCEEVRKHYQEPGGTLPALSAVDVIKAG
MLBr_00156|M.leprae_Br4923          -----------KIIVMIGEIGGDAEERAADYIKANVSKPVVGYVAGFTAP
MSMEG_0666|M.smegmatis_MC2_155      -------------PLVVVAAGGVAVELHGDRVVVCPPVSRTTARRIVDQL
MUL_2920|M.ulcerans_Agy99           --------------PMVRRGYVTAFAAPANELP-----TAQDSYSHNTSP
MMAR_2406|M.marinum_M               -----------HFDTYICHRDDNLRDREPDEVPELLRDALIAEGVAPDAI
                                                    :            .        .           

Mb1419|M.bovis_AF2122/97            EVNMVINTPYGNSGPRIDGYEIRSAAVAGNIPCITTVQGASAAVQGIEAG
Rv1384|M.tuberculosis_H37Rv         EVNMVINTPYGNSGPRIDGYEIRSAAVAGNIPCITTVQGASAAVQGIEAG
MAV_3389|M.avium_104                EVDMVINTPYGNSGPRIDGYEIRSAAVSVNIPCVTTVQGASAAVQGIEAG
MAB_2827c|M.abscessus_ATCC_199      DVAMVINTPYGNSGPRVDGYEIRSAAVSMNIPCITTVQGASAAVQGIEAG
MLBr_00156|M.leprae_Br4923          EG-----KTMGHAG-----------AIVSGSSGTAAVKKDALEAAGVKVG
MSMEG_0666|M.smegmatis_MC2_155      RIAPLLTGWRGGPVADID----ALVDVIVAFSAMAVELGDMLDAVEANPV
MUL_2920|M.ulcerans_Agy99           QLVVIAERAAGSSRDDPQPAIQAIRAAVANRHGLAVAEVRFLPAGAIPRT
MMAR_2406|M.marinum_M               SIIGEEEQALDAALEQAQPDDLVLYFCEAITRCWKQIIHFTPKFTAPEPE
                                              . .                                     

Mb1419|M.bovis_AF2122/97            IRGDIGVRSLQELHRVIGGVER----------
Rv1384|M.tuberculosis_H37Rv         IRGDIGVRSLQELHRVIGGVER----------
MAV_3389|M.avium_104                IRGDIGVRSLQELHSQIASDKGPR--------
MAB_2827c|M.abscessus_ATCC_199      IRGDIGVRSLQELHAGLR--------------
MLBr_00156|M.leprae_Br4923          KTPSETAVLVREILCTL---------------
MSMEG_0666|M.smegmatis_MC2_155      IVSATGAVAVDALVVPNSVPG-----------
MUL_2920|M.ulcerans_Agy99           TSGKLARRACRGQYLGGVLGVH----------
MMAR_2406|M.marinum_M               SVAKRLATSIFDVPDGFALTSDDRGVLIVPAK