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VTPAQPSGISRRKLFGAAGVTAAVVGAASAGALAGRASAAANAPHGALSGPVPFRGERQAGIITEAQDRM HFCAFDVTTDSREDVIALLKQWTQMAERMTKGEETEPDGAVGGNPYSPPTDTGEALGLPASQLTLTIGFG PGFFSKDGKDRFGIADQQPAELKPLPKFPNETMDPARSGGDICIQACANDPQVAVHAIRNLARVGFGTVA VRYSQLGFGRTSSTTRDQATPRNLFGFKDGTSNIKADETDSLNEHVWVGDGDGPAWLTGGTYLLTRRIRM RIENWDRTTLLEQERVIGRQKGSGAPNGLQDEFEELDFDMTDAKGKPMIDVDAHVRLVSPQNLGGIEILR RGYNFTDGTDGFGHLDAGLFFIAFVRSPEKQFIPMLSEMSRKDALNEYITHTGTAIFACPPGIPEGDASA YWGSTLFS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5420 | - | - | 100% (428) | Tat-translocated enzyme |
| M. smegmatis MC2 155 | MSMEG_6567 | - | 1e-50 | 33.65% (416) | iron-dependent peroxidase |
| M. smegmatis MC2 155 | MSMEG_5829 | - | 1e-07 | 25.60% (250) | Dyp-type peroxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0822c | - | 2e-05 | 24.40% (250) | hypothetical protein Mb0822c |
| M. gilvum PYR-GCK | Mflv_1950 | - | 0.0 | 75.86% (435) | Dyp-type peroxidase family protein |
| M. tuberculosis H37Rv | Rv0799c | - | 2e-05 | 24.40% (250) | hypothetical protein Rv0799c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1161c | - | 1e-173 | 70.62% (422) | hypothetical protein MAB_1161c |
| M. marinum M | MMAR_4892 | - | 2e-06 | 24.40% (250) | hypothetical protein MMAR_4892 |
| M. avium 104 | MAV_2485 | - | 6e-81 | 42.86% (420) | Tat-translocated enzyme |
| M. thermoresistible (build 8) | TH_2943 | - | 2e-60 | 36.07% (427) | PUTATIVE Dyp-type peroxidase family |
| M. ulcerans Agy99 | MUL_0406 | - | 1e-06 | 24.40% (250) | hypothetical protein MUL_0406 |
| M. vanbaalenii PYR-1 | Mvan_4775 | - | 0.0 | 77.75% (427) | Dyp-type peroxidase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1950|M.gilvum_PYR-GCK MSSRHSERSSQSGHSDPMTPAQGRTGAGPERSGLSRRKLFG---AAGVTA
Mvan_4775|M.vanbaalenii_PYR-1 MSSHP--------NNENAEPAQ------PERSGLSRRKLFG---AAGVTA
MSMEG_5420|M.smegmatis_MC2_155 -----------------MTPAQ--------PSGISRRKLFG---AAGVTA
MAB_1161c|M.abscessus_ATCC_199 -----------------------------MSTGLNRRKLLG---AAGVTA
MAV_2485|M.avium_104 MTDDPIEPTDGAPKSEGVEPDS---------TAVSRRRALGGAVLAGLSG
TH_2943|M.thermoresistible__bu VTGPDG------------------------RRGISRRRFVAG--TLGAGA
Mb0822c|M.bovis_AF2122/97 --------------------------------------------------
Rv0799c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4892|M.marinum_M --------------------------------------------------
MUL_0406|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1950|M.gilvum_PYR-GCK AVVGAAGAGAFAGRATAAQA----PDH--LLTAVPFRGT-HQAGIVTEAQ
Mvan_4775|M.vanbaalenii_PYR-1 AVVGAAGVGALAGRASAAQP----PNH--LDTAVPFRGQ-HQAGIVTEAQ
MSMEG_5420|M.smegmatis_MC2_155 AVVGAASAGALAGRASAAAN----APHGALSGPVPFRGE-RQAGIITEAQ
MAB_1161c|M.abscessus_ATCC_199 AVAGAAGAGVLGGRASAAST----GPVN---VKVPFRGD-HQAGIVTPAQ
MAV_2485|M.avium_104 AAIGAVGGG-FAGHAVAAGQRGDDHDTVDLRRSYPFYGQPHQGGIDTPPQ
TH_2943|M.thermoresistible__bu AVGAAAMVPGCAGRQDDSLP--------DSPRFVPFEGP-HQTGITALPV
Mb0822c|M.bovis_AF2122/97 -------------------------------MAVPAVSP---QPILAPLT
Rv0799c|M.tuberculosis_H37Rv -------------------------------MAVPAVSP---QPILAPLT
MMAR_4892|M.marinum_M ---------------------------------MPSVQP---QPILAPLT
MUL_0406|M.ulcerans_Agy99 ---------------------------------MPSVQP---QPILAPLT
* * :
Mflv_1950|M.gilvum_PYR-GCK DRMHFATFDVTTKS-RQDVIKMLADWTEMAERMTQGKEAFPNGSTG-QNP
Mvan_4775|M.vanbaalenii_PYR-1 DRMHFATFDVTTKS-RDDVIKMLADWTEMAERMTQGEEAFPNGSIG-QNP
MSMEG_5420|M.smegmatis_MC2_155 DRMHFCAFDVTTDS-REDVIALLKQWTQMAERMTKGEETEPDGAVG-GNP
MAB_1161c|M.abscessus_ATCC_199 DRMHFCAFDVMPNATRGEVQAMLRQWTEMADRMTRGEETTSGGAVD-GNP
MAV_2485|M.avium_104 RYAMFMSFSLASGAGRTELQTLLARWSAAAAILQQGK---PVGTVQPQVD
TH_2943|M.thermoresistible__bu PRLGLLASFKVVSDDRSRLALVLRELTDEIRGLMAGR------PPEVRDP
Mb0822c|M.bovis_AF2122/97 PAAIFLVATIGADG-EATVHDALSKISGLVRAIGFRD-------------
Rv0799c|M.tuberculosis_H37Rv PAAIFLVATIGADG-EATVHDALSKISGLVRAIGFRD-------------
MMAR_4892|M.marinum_M PAAIFLVATIDAGG-EQTVHDALTEISGLVRAIGFRD-------------
MUL_0406|M.ulcerans_Agy99 PAAIFLVATIDAGG-EQTVHDALTEISGLVRAIGFRD-------------
: . : * : :
Mflv_1950|M.gilvum_PYR-GCK YSPPSDTGEALGLPPSQ-LTLTIGFGPSFFLKDGVDRFGIADKKPAELVD
Mvan_4775|M.vanbaalenii_PYR-1 YSPPSDTGEALGLPPSQ-LTLTIGFGPSFFVKDGVDRFGIADKKPAELVD
MSMEG_5420|M.smegmatis_MC2_155 YSPPTDTGEALGLPASQ-LTLTIGFGPGFFSKDGKDRFGIADQQPAELKP
MAB_1161c|M.abscessus_ATCC_199 YSPPTDTGEALDLAASA-LTLTIGFGPSFFRKDGVDRFGIADKLPPPLQE
MAV_2485|M.avium_104 VQPPADTGEADGLSPAS-LTVTIGLGPSLFG----DRFGLAARRPAVFTD
TH_2943|M.thermoresistible__bu AYPPVDSGILGAQPPPDDLSVVVGVGASVFD----DRFGLADRRPNELVT
Mb0822c|M.bovis_AF2122/97 --------------PTKHLSVVVSIGSDAWDR------LFAGPRPTELHP
Rv0799c|M.tuberculosis_H37Rv --------------PTKHLSVVVSIGSDAWDR------LFAGPRPTELHP
MMAR_4892|M.marinum_M --------------PTKHLSVVASIGSDAWDR------LFSGPKPAELHP
MUL_0406|M.ulcerans_Agy99 --------------PTKHLSVVASIGADAWDR------LFSGPKPAELHP
.. *::. ..*.. : :: * :
Mflv_1950|M.gilvum_PYR-GCK LPKFPNEKIDPARSGGDIVVQACSNDPQVAVHAIRNLARIGFGTVAVRYS
Mvan_4775|M.vanbaalenii_PYR-1 LPKFPNEKIDPARSGGDIVVQACANDPQVAVHAIRNLARIGFGTVAVRYS
MSMEG_5420|M.smegmatis_MC2_155 LPKFPNETMDPARSGGDICIQACANDPQVAVHAIRNLARVGFGTVAVRYS
MAB_1161c|M.abscessus_ATCC_199 LPKFRNEKLDPARCGGDICIQACADDPQVAVHAIRNLARVGFGTVAVKWS
MAV_2485|M.avium_104 LPPLNGDNLDPRLHGGDLSVQACADDPQVCYHAVRNLARLGRNIVSPFWA
TH_2943|M.thermoresistible__bu MPFLANDRLDPKLSHGDLLLSLEAGHTDTLQFALRQLMRRTRRDLVLHWM
Mb0822c|M.bovis_AF2122/97 FVELTGPRHTAPATPGDLLFHIRAETMDVCFELAGRILKSMGDAVTVVDE
Rv0799c|M.tuberculosis_H37Rv FVELTGPRHTAPATPGDLLFHIRAETMDVCFELAGRILKSMGDAVTVVDE
MMAR_4892|M.marinum_M FVPLTGPRHNAPATPGDLLLHIRAETMDVCFELAGRILKAMAPAVTVVDE
MUL_0406|M.ulcerans_Agy99 FVPLTGPRHNAPATPGDLLLHIRAETMDVCFELAGRILKAMAPAVTVVDE
: : . . **: . : :. .: : :
Mflv_1950|M.gilvum_PYR-GCK QLGFGRTSSTTRDQSTPRNLFGFKDGTANLRSDETEKLNKFVWVA-DGDG
Mvan_4775|M.vanbaalenii_PYR-1 QLGFGRTSSTTRDQTTPRNLFGFKDGTANMRSDETDRLNKSVWVA-DGDG
MSMEG_5420|M.smegmatis_MC2_155 QLGFGRTSSTTRDQATPRNLFGFKDGTSNIKADETDSLNEHVWVG-DGDG
MAB_1161c|M.abscessus_ATCC_199 QLGFGRTSSTSRSQVTPRNLFGFKDGTRNIKAEDTAKVDSSVWVA-KGDD
MAV_2485|M.avium_104 VLGFGRASAGP-GQHTPRNLLGFKDGTRNIAS--QAEYDRFVWVD-DSDQ
TH_2943|M.thermoresistible__bu IDGYARGAGSGVPTETPRNLLGFKDGTANLDSGDAALMDRYVWVGSDDGE
Mb0822c|M.bovis_AF2122/97 VHGFR--------FFDNRDLLGFVDGTENPSG------PIAIKATTIGDE
Rv0799c|M.tuberculosis_H37Rv VHGFR--------FFDNRDLLGFVDGTENPSG------PIAIKATTIGDE
MMAR_4892|M.marinum_M VHGFR--------FFDNRDLLGFVDGTENPGG------AIAIGATTVGDE
MUL_0406|M.ulcerans_Agy99 VHGFR--------FFDNRDLLGFVDGTENPGG------AIAIGATTVGDE
*: *:*:** *** * . : . ..
Mflv_1950|M.gilvum_PYR-GCK PSWMTGGSYLVARRIRMRIEQWDRTTLLEQERVIGRQKGSGAPMGLTDEF
Mvan_4775|M.vanbaalenii_PYR-1 PAWLTGGTYLVARRIRMLIEQWDRTTLLEQERVIGRQKGSGAPMGLDDEF
MSMEG_5420|M.smegmatis_MC2_155 PAWLTGGTYLLTRRIRMRIENWDRTTLLEQERVIGRQKGSGAPNGLQDEF
MAB_1161c|M.abscessus_ATCC_199 PAWMAGGTYLVARRIRMLIESWDRTVLTEQERVIGRAKGSGAPIGQADEF
MAV_2485|M.avium_104 P-WMNGGTYQVVRKIRMLLETWDVDRIGNQQRIFGRTKEEGAPLSGRHEF
TH_2943|M.thermoresistible__bu PDWAVGGSYQVVRLIRMFVEFWDRTRLAEQEAIFGRHKVSGAPLGMSDEF
Mb0822c|M.bovis_AF2122/97 DRNFAGSCYVHVQKYVHDMASWESLSVTEQERVIGRTKLDDIELDDNAKP
Rv0799c|M.tuberculosis_H37Rv DRNFAGSCYVHVQKYVHDMASWESLSVTEQERVIGRTKLDDIELDDNAKP
MMAR_4892|M.marinum_M DPDFAGSCYVHVQKYVHDMGSWDSLSVTEQERVIGRTKLEDIELDESTKP
MUL_0406|M.ulcerans_Agy99 DPDFAGSCYVHVQKYVHDMGSWDSLSVTEQERVIGRTKLEDIELDESTKP
*. * .: : *: : :*: ::** * .. . :
Mflv_1950|M.gilvum_PYR-GCK EELDFDLTNDKDEPLIDTLAHVRLASPENLGGIEILRRGYNFTDGSDGFG
Mvan_4775|M.vanbaalenii_PYR-1 QELNFDLTNDKDEPLIDPVAHVRLASSKNLGGIEILRRGYNFTDGSDGFG
MSMEG_5420|M.smegmatis_MC2_155 EELDFDMTDAKGKPMIDVDAHVRLVSPQNLGGIEILRRGYNFTDGTDGFG
MAB_1161c|M.abscessus_ATCC_199 AALDFTGKKPDGEPLLDVDSHVRLASAEELGGIEILRRGYNFTDGSDGFG
MAV_2485|M.avium_104 DTPDFTAKGADGNPLIDPMSHVGLAARENNDGIMIRRRSYNYTDGLDANG
TH_2943|M.thermoresistible__bu DDPDYASDPDGERIPLNAHIRLANPRTPETEDNLLLRRGFSYARGFDGAG
Mb0822c|M.bovis_AF2122/97 ANSHVALNVITDDDGTERKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVTE
Rv0799c|M.tuberculosis_H37Rv ANSHVALNVITDDDGTERKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVTE
MMAR_4892|M.marinum_M ANSHIALNVITDEDGVELKIVRHNMPFGEVGKGEYGTYFIGYSRTPVVTE
MUL_0406|M.ulcerans_Agy99 ANSHIALNVITDEDGVELKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVTE
. : : .::
Mflv_1950|M.gilvum_PYR-GCK HLDAGLFFIAFVRNPVTQFVPMQNAISRDDAMNEYVTPTS--SAVFACPP
Mvan_4775|M.vanbaalenii_PYR-1 HLDAGLFFIAFVRNPVTQFVPMQNAISRNDAMNEYVRPTS--SAVFACPP
MSMEG_5420|M.smegmatis_MC2_155 HLDAGLFFIAFVRSPEKQFIPMLSEMSRKDALNEYITHTG--TAIFACPP
MAB_1161c|M.abscessus_ATCC_199 HLDAGLFFIAFVRNPQTQFIPMQRKLATEDALNEYILHTG--SAIFACPP
MAV_2485|M.avium_104 QLNAGLLFISYQKDPQ-DFIRLQNRLGAHDLLNEYIRHIG--SAIFAVPP
TH_2943|M.thermoresistible__bu RLDQGLAFVCYQRSLRRGFLAVQERLKG-EPLEEYILPVG--GGFFFALP
Mb0822c|M.bovis_AF2122/97 QMLR-NMFLGDPAGNTDRVLDFSTAVTGGLFFSPTIDFLDHPPPLP--QA
Rv0799c|M.tuberculosis_H37Rv QMLR-NMFLGDPAGNTDRVLDFSTAVTGGLFFSPTIDFLDHPPPLP--QA
MMAR_4892|M.marinum_M RLLR-NMFLGDPPGNTDRVLDFSTATTGGLFFSPTIDFLDDPPPLPPAPA
MUL_0406|M.ulcerans_Agy99 RLLR-NMFLGDSPGNTDRVLDFSTATTGGLFFSPTIDFLDDPPPLPLAPA
:: *: . .: . :. : . . .
Mflv_1950|M.gilvum_PYR-GCK GIPEGDTSSFWGSTLFD---
Mvan_4775|M.vanbaalenii_PYR-1 GIPEGDKSTFWGSTLFD---
MSMEG_5420|M.smegmatis_MC2_155 GIPEGDASAYWGSTLFS---
MAB_1161c|M.abscessus_ATCC_199 GLGPKE---YWGQALFG---
MAV_2485|M.avium_104 APAEGH---YIAQSLFR---
TH_2943|M.thermoresistible__bu GVSEPDR--YLGDALVD---
Mb0822c|M.bovis_AF2122/97 ATPTLAAGSLSIGSLKGSPR
Rv0799c|M.tuberculosis_H37Rv ATPTLAAGSLSIGSLKGSPR
MMAR_4892|M.marinum_M AVPTTDDGSLSIGSLKGISE
MUL_0406|M.ulcerans_Agy99 AVPTADDGSLSIGSLKGTSE
. :*