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MTDDPIEPTDGAPKSEGVEPDSTAVSRRRALGGAVLAGLSGAAIGAVGGGFAGHAVAAGQRGDDHDTVDL RRSYPFYGQPHQGGIDTPPQRYAMFMSFSLASGAGRTELQTLLARWSAAAAILQQGKPVGTVQPQVDVQP PADTGEADGLSPASLTVTIGLGPSLFGDRFGLAARRPAVFTDLPPLNGDNLDPRLHGGDLSVQACADDPQ VCYHAVRNLARLGRNIVSPFWAVLGFGRASAGPGQHTPRNLLGFKDGTRNIASQAEYDRFVWVDDSDQPW MNGGTYQVVRKIRMLLETWDVDRIGNQQRIFGRTKEEGAPLSGRHEFDTPDFTAKGADGNPLIDPMSHVG LAARENNDGIMIRRRSYNYTDGLDANGQLNAGLLFISYQKDPQDFIRLQNRLGAHDLLNEYIRHIGSAIF AVPPAPAEGHYIAQSLFR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2485 | - | - | 100% (438) | Tat-translocated enzyme |
| M. avium 104 | MAV_0741 | - | 2e-05 | 24.77% (218) | Dyp-type peroxidase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0822c | - | 1e-06 | 25.21% (238) | hypothetical protein Mb0822c |
| M. gilvum PYR-GCK | Mflv_1950 | - | 3e-90 | 44.42% (439) | Dyp-type peroxidase family protein |
| M. tuberculosis H37Rv | Rv0799c | - | 1e-06 | 25.21% (238) | hypothetical protein Rv0799c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1161c | - | 3e-95 | 46.96% (428) | hypothetical protein MAB_1161c |
| M. marinum M | MMAR_4892 | - | 3e-08 | 26.05% (238) | hypothetical protein MMAR_4892 |
| M. smegmatis MC2 155 | MSMEG_5420 | - | 8e-81 | 42.86% (420) | Tat-translocated enzyme |
| M. thermoresistible (build 8) | TH_1583 | - | 8e-71 | 41.49% (417) | iron-dependent peroxidase |
| M. ulcerans Agy99 | MUL_0406 | - | 2e-08 | 26.05% (238) | hypothetical protein MUL_0406 |
| M. vanbaalenii PYR-1 | Mvan_4775 | - | 8e-89 | 44.39% (428) | Dyp-type peroxidase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1950|M.gilvum_PYR-GCK MSSRHSERSSQSGHSDPMTPAQGRTGAGPERSGLSRRKLFG---AAGVTA
Mvan_4775|M.vanbaalenii_PYR-1 MSSHP--------NNENAEPAQ------PERSGLSRRKLFG---AAGVTA
MSMEG_5420|M.smegmatis_MC2_155 -----------------MTPAQ--------PSGISRRKLFG---AAGVTA
MAB_1161c|M.abscessus_ATCC_199 -----------------------------MSTGLNRRKLLG---AAGVTA
MAV_2485|M.avium_104 MTDDPIEPTDGAPKSEGVEPDS---------TAVSRRRALGGAVLAGLSG
TH_1583|M.thermoresistible__bu MGDRADTAR---------------------DITISRRRLLAG------GA
Mb0822c|M.bovis_AF2122/97 --------------------------------------------------
Rv0799c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4892|M.marinum_M --------------------------------------------------
MUL_0406|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1950|M.gilvum_PYR-GCK AVVGAAGAGAFAGRATAAQA----PDH--LLTAVPFRGT-HQAGIVTEAQ
Mvan_4775|M.vanbaalenii_PYR-1 AVVGAAGVGALAGRASAAQP----PNH--LDTAVPFRGQ-HQAGIVTEAQ
MSMEG_5420|M.smegmatis_MC2_155 AVVGAASAGALAGRASAAAN----APHGALSGPVPFRGE-RQAGIITEAQ
MAB_1161c|M.abscessus_ATCC_199 AVAGAAGAGVLGGRASAAST----GPVN---VKVPFRGD-HQAGIVTPAQ
MAV_2485|M.avium_104 AAIGAVGGG-FAGHAVAAGQRGDDHDTVDLRRSYPFYGQPHQGGIDTPPQ
TH_1583|M.thermoresistible__bu AAIGAAGAAWSVGRAGAGTVA---PDTTFGAEVVPFHGV-HQAGIQTPPQ
Mb0822c|M.bovis_AF2122/97 -------------------------------MAVPAVSP---QPILAPLT
Rv0799c|M.tuberculosis_H37Rv -------------------------------MAVPAVSP---QPILAPLT
MMAR_4892|M.marinum_M ---------------------------------MPSVQP---QPILAPLT
MUL_0406|M.ulcerans_Agy99 ---------------------------------MPSVQP---QPILAPLT
* * :
Mflv_1950|M.gilvum_PYR-GCK DRMHFATFDVTTKS----RQDVIKMLADWTEMAERMTQGKEAFPNGSTG-
Mvan_4775|M.vanbaalenii_PYR-1 DRMHFATFDVTTKS----RDDVIKMLADWTEMAERMTQGEEAFPNGSIG-
MSMEG_5420|M.smegmatis_MC2_155 DRMHFCAFDVTTDS----REDVIALLKQWTQMAERMTKGEETEPDGAVG-
MAB_1161c|M.abscessus_ATCC_199 DRMHFCAFDVMPNAT---RGEVQAMLRQWTEMADRMTRGEETTSGGAVD-
MAV_2485|M.avium_104 RYAMFMSFSLASGAG---RTELQTLLARWSAAAAILQQGK---PVGTVQP
TH_1583|M.thermoresistible__bu AHALFTALDLRADSGRSPRQALTAVLRLWTADAERLTQGR----------
Mb0822c|M.bovis_AF2122/97 PAAIFLVATIGADG----EATVHDALSKISGLVRAIGFRD----------
Rv0799c|M.tuberculosis_H37Rv PAAIFLVATIGADG----EATVHDALSKISGLVRAIGFRD----------
MMAR_4892|M.marinum_M PAAIFLVATIDAGG----EQTVHDALTEISGLVRAIGFRD----------
MUL_0406|M.ulcerans_Agy99 PAAIFLVATIDAGG----EQTVHDALTEISGLVRAIGFRD----------
* : . . . : * : . :
Mflv_1950|M.gilvum_PYR-GCK QNPYSPPSDTGEALGLPPSQLTLTIGFGPSFFLKDGVDRFGIADKKPAEL
Mvan_4775|M.vanbaalenii_PYR-1 QNPYSPPSDTGEALGLPPSQLTLTIGFGPSFFVKDGVDRFGIADKKPAEL
MSMEG_5420|M.smegmatis_MC2_155 GNPYSPPTDTGEALGLPASQLTLTIGFGPGFFSKDGKDRFGIADQQPAEL
MAB_1161c|M.abscessus_ATCC_199 GNPYSPPTDTGEALDLAASALTLTIGFGPSFFRKDGVDRFGIADKLPPPL
MAV_2485|M.avium_104 QVDVQPPADTGEADGLSPASLTVTIGLGPSLFG----DRFGLAARRPAVF
TH_1583|M.thermoresistible__bu ----PALADTEPELAHRPARLTVTVGLGPELFD-----KIGMSHARPPSA
Mb0822c|M.bovis_AF2122/97 ----------------PTKHLSVVVSIGSDAWDR------LFAGPRPTEL
Rv0799c|M.tuberculosis_H37Rv ----------------PTKHLSVVVSIGSDAWDR------LFAGPRPTEL
MMAR_4892|M.marinum_M ----------------PTKHLSVVASIGSDAWDR------LFSGPKPAEL
MUL_0406|M.ulcerans_Agy99 ----------------PTKHLSVVASIGADAWDR------LFSGPKPAEL
. *::. .:*. : :: *.
Mflv_1950|M.gilvum_PYR-GCK VDLPKFPNEKIDPARSGGDIVVQACSNDPQVAVHAIRNLARIGFGTVAVR
Mvan_4775|M.vanbaalenii_PYR-1 VDLPKFPNEKIDPARSGGDIVVQACANDPQVAVHAIRNLARIGFGTVAVR
MSMEG_5420|M.smegmatis_MC2_155 KPLPKFPNETMDPARSGGDICIQACANDPQVAVHAIRNLARVGFGTVAVR
MAB_1161c|M.abscessus_ATCC_199 QELPKFRNEKLDPARCGGDICIQACADDPQVAVHAIRNLARVGFGTVAVK
MAV_2485|M.avium_104 TDLPPLNGDNLDPRLHGGDLSVQACADDPQVCYHAVRNLARLGRNIVSPF
TH_1583|M.thermoresistible__bu RQLPAFTIDRLDPRWCGGDLFLQICADDPMVVAHTARVLLKNVRTLARPR
Mb0822c|M.bovis_AF2122/97 HPFVELTGPRHTAPATPGDLLFHIRAETMDVCFELAGRILKSMGDAVTVV
Rv0799c|M.tuberculosis_H37Rv HPFVELTGPRHTAPATPGDLLFHIRAETMDVCFELAGRILKSMGDAVTVV
MMAR_4892|M.marinum_M HPFVPLTGPRHNAPATPGDLLLHIRAETMDVCFELAGRILKAMAPAVTVV
MUL_0406|M.ulcerans_Agy99 HPFVPLTGPRHNAPATPGDLLLHIRAETMDVCFELAGRILKAMAPAVTVV
: : . **: .: :: * . : : .
Mflv_1950|M.gilvum_PYR-GCK YSQLGFGRTSSTTRDQSTPRNLFGFKDGTANLRSDETEKLNKFVWVADGD
Mvan_4775|M.vanbaalenii_PYR-1 YSQLGFGRTSSTTRDQTTPRNLFGFKDGTANMRSDETDRLNKSVWVADGD
MSMEG_5420|M.smegmatis_MC2_155 YSQLGFGRTSSTTRDQATPRNLFGFKDGTSNIKADETDSLNEHVWVGDGD
MAB_1161c|M.abscessus_ATCC_199 WSQLGFGRTSSTSRSQVTPRNLFGFKDGTRNIKAEDTAKVDSSVWVAKGD
MAV_2485|M.avium_104 WAVLGFGRASAGP-GQHTPRNLLGFKDGTRNIAS--QAEYDRFVWVDDSD
TH_1583|M.thermoresistible__bu WRQVGFRTARGADAPDVTMRNLFGQVDGTVNPDE---ADFAELVWMDGRQ
Mb0822c|M.bovis_AF2122/97 DEVHGFR--------FFDNRDLLGFVDGTENPSG---PIAIKATTIGDED
Rv0799c|M.tuberculosis_H37Rv DEVHGFR--------FFDNRDLLGFVDGTENPSG---PIAIKATTIGDED
MMAR_4892|M.marinum_M DEVHGFR--------FFDNRDLLGFVDGTENPGG---AIAIGATTVGDED
MUL_0406|M.ulcerans_Agy99 DEVHGFR--------FFDNRDLLGFVDGTENPGG---AIAIGATTVGDED
** *:*:* *** * . : :
Mflv_1950|M.gilvum_PYR-GCK GPSWMTGGSYLVARRIRMRIEQWDRTTLLEQERVIGRQKGSGAPMGLTDE
Mvan_4775|M.vanbaalenii_PYR-1 GPAWLTGGTYLVARRIRMLIEQWDRTTLLEQERVIGRQKGSGAPMGLDDE
MSMEG_5420|M.smegmatis_MC2_155 GPAWLTGGTYLLTRRIRMRIENWDRTTLLEQERVIGRQKGSGAPNGLQDE
MAB_1161c|M.abscessus_ATCC_199 DPAWMAGGTYLVARRIRMLIESWDRTVLTEQERVIGRAKGSGAPIGQADE
MAV_2485|M.avium_104 QP-WMNGGTYQVVRKIRMLLETWDVDRIGNQQRIFGRTKEEGAPLSGRHE
TH_1583|M.thermoresistible__bu QP-WSAGGSLAVVRRIAMNLDTWDELGRDARELTVGRRLDNGAPLTGRHE
Mb0822c|M.bovis_AF2122/97 RN--FAGSCYVHVQKYVHDMASWESLSVTEQERVIGRTKLDDIELDDNAK
Rv0799c|M.tuberculosis_H37Rv RN--FAGSCYVHVQKYVHDMASWESLSVTEQERVIGRTKLDDIELDDNAK
MMAR_4892|M.marinum_M PD--FAGSCYVHVQKYVHDMGSWDSLSVTEQERVIGRTKLEDIELDESTK
MUL_0406|M.ulcerans_Agy99 PD--FAGSCYVHVQKYVHDMGSWDSLSVTEQERVIGRTKLEDIELDESTK
*. .:: : *: :: .** .. :
Mflv_1950|M.gilvum_PYR-GCK FEELDFDLTNDKDEPLIDTLAHVRLASPENLGGIEILRRGYNFTDGSDGF
Mvan_4775|M.vanbaalenii_PYR-1 FQELNFDLTNDKDEPLIDPVAHVRLASSKNLGGIEILRRGYNFTDGSDGF
MSMEG_5420|M.smegmatis_MC2_155 FEELDFDMTDAKGKPMIDVDAHVRLVSPQNLGGIEILRRGYNFTDGTDGF
MAB_1161c|M.abscessus_ATCC_199 FAALDFTGKKPDGEPLLDVDSHVRLASAEELGGIEILRRGYNFTDGSDGF
MAV_2485|M.avium_104 FDTPDFTAKGADGNPLIDPMSHVGLAARENNDGIMIRRRSYNYTDGLDAN
TH_1583|M.thermoresistible__bu TDEPDLTMLR-NGIPVIPPNSHVARARHRTPE-ERFLRRSYNYDDPPADD
Mb0822c|M.bovis_AF2122/97 PANSHVALNVITDDDGTERKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVT
Rv0799c|M.tuberculosis_H37Rv PANSHVALNVITDDDGTERKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVT
MMAR_4892|M.marinum_M PANSHIALNVITDEDGVELKIVRHNMPFGEVGKGEYGTYFIGYSRTPVVT
MUL_0406|M.ulcerans_Agy99 PANSHIALNVITDEDGVELKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVT
.. . .:
Mflv_1950|M.gilvum_PYR-GCK GHLDAGLFFIAFVRNPVTQFVPMQNAISRDDAMNEYVTPTS--SAVFACP
Mvan_4775|M.vanbaalenii_PYR-1 GHLDAGLFFIAFVRNPVTQFVPMQNAISRNDAMNEYVRPTS--SAVFACP
MSMEG_5420|M.smegmatis_MC2_155 GHLDAGLFFIAFVRSPEKQFIPMLSEMSRKDALNEYITHTG--TAIFACP
MAB_1161c|M.abscessus_ATCC_199 GHLDAGLFFIAFVRNPQTQFIPMQRKLATEDALNEYILHTG--SAIFACP
MAV_2485|M.avium_104 GQLNAGLLFISYQKDPQ-DFIRLQNRLGAHDLLNEYIRHIG--SAIFAVP
TH_1583|M.thermoresistible__bu RTSDAGLIFVSYQRDIDRQFLPVQQRLADADALNEWTTPIG--SAVFVIL
Mb0822c|M.bovis_AF2122/97 EQMLR-NMFLGDPAGNTDRVLDFSTAVTGGLFFSPTIDFLDHPPPLP--Q
Rv0799c|M.tuberculosis_H37Rv EQMLR-NMFLGDPAGNTDRVLDFSTAVTGGLFFSPTIDFLDHPPPLP--Q
MMAR_4892|M.marinum_M ERLLR-NMFLGDPPGNTDRVLDFSTATTGGLFFSPTIDFLDDPPPLPPAP
MUL_0406|M.ulcerans_Agy99 ERLLR-NMFLGDSPGNTDRVLDFSTATTGGLFFSPTIDFLDDPPPLPLAP
:*:. . .: . :. . ..:
Mflv_1950|M.gilvum_PYR-GCK PGIPEGDTSSFWGSTLFD---
Mvan_4775|M.vanbaalenii_PYR-1 PGIPEGDKSTFWGSTLFD---
MSMEG_5420|M.smegmatis_MC2_155 PGIPEGDASAYWGSTLFS---
MAB_1161c|M.abscessus_ATCC_199 PGLGPKE---YWGQALFG---
MAV_2485|M.avium_104 PAPAEGH---YIAQSLFR---
TH_1583|M.thermoresistible__bu PGVAPGG---YLGESLLSG--
Mb0822c|M.bovis_AF2122/97 AATPTLAAGSLSIGSLKGSPR
Rv0799c|M.tuberculosis_H37Rv AATPTLAAGSLSIGSLKGSPR
MMAR_4892|M.marinum_M AAVPTTDDGSLSIGSLKGISE
MUL_0406|M.ulcerans_Agy99 AAVPTADDGSLSIGSLKGTSE
.. :*