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M. smegmatis MC2 155 MSMEG_5381 (-)

annotation: hypothetical protein MSMEG_5381
coordinates: 5461316 - 5462167
length: 283

PPLPPAPGLDAPLPPLPPEPAMASPRPWWVALPPSPPAPAYDANPPLPPAPAVAFAVEATLVMIASPPAP
PLPGFELPFPPFPPAPPVTVPRPADWAEPPLPPRPTLSWPKLELPPAPPVAAAAATAGAAGGGGRRRGVG
DGGVAPVSAVAAVAVASAAVGDATDAAGDAAQPGGGGVTARAAVPSAAGRVKASAAPGAALAAGHIRCRF
GVVDGRVTAVAADATGAAFSGAPISSGATDRRRGRARRAGDGGVAAGTTVTGAGRVGVTVAVTAVAAGAA
QC*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5381--100% (283)hypothetical protein MSMEG_5381
M. smegmatis MC2 155MSMEG_5700-7e-1534.60% (211) secreted protein
M. smegmatis MC2 155MSMEG_5583-2e-1132.35% (170) HNH endonuclease

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3906-7e-1136.15% (130) hypothetical protein Mb3906
M. gilvum PYR-GCKMflv_3843-5e-2237.66% (231) hypothetical protein Mflv_3843
M. tuberculosis H37RvRv3879c-4e-1128.09% (267) hypothetical protein Rv3879c
M. leprae Br4923MLBr_00048-2e-0729.33% (208) hypothetical protein MLBr_00048
M. abscessus ATCC 19977MAB_3131c-8e-1230.74% (231) translation initiation factor IF-2 (InfB)
M. marinum MMMAR_5451-6e-1540.28% (144) hypothetical protein MMAR_5451
M. avium 104MAV_4827-5e-1327.52% (298) hypothetical protein MAV_4827
M. thermoresistible (build 8)TH_4426-6e-0827.36% (201) PUTATIVE AAA ATPase
M. ulcerans Agy99MUL_2122infB6e-1132.59% (224) translation initiation factor IF-2
M. vanbaalenii PYR-1Mvan_2552-4e-2234.56% (217) hypothetical protein Mvan_2552

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3843|M.gilvum_PYR-GCK          MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQIVTR
Mvan_2552|M.vanbaalenii_PYR-1       MSRTKKSIVVVMMGSAGLFLSAPLLGPSANATPTRGGVPCVGILQQVISR
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            ----------MAADYDKLFRPHEGMEAPDDMAAQP------------FFD
MLBr_00048|M.leprae_Br4923          ----------MAADYDKLFRLDDGAYASPDQAAEQ------------LFD
MMAR_5451|M.marinum_M               ----------MPADYDELFQPAEGSGPPDDETGQT------------FFD
MAB_3131c|M.abscessus_ATCC_199      -----------MAGKARVHELAKELGVTSKEVLAR------------LSD
MUL_2122|M.ulcerans_Agy99           -----------MAGKARVHELAKELGVTSKEVLAR------------LSE
MAV_4827|M.avium_104                --------MNIVLGVSMAPSSIQMVVLEGEYADG----------------
Rv3879c|M.tuberculosis_H37Rv        ----------MSITRPTGSYARQMLDPGG---------------------
TH_4426|M.thermoresistible__bu      ----------VVRPAHPLYCAAVRAELTEPEVRGVR--------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          PGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVPGRPPASVV
Mvan_2552|M.vanbaalenii_PYR-1       PGDIPQALTETARSFTNPGQPAPPVVRPPASSSSSVGTPPVPPTPPGSVV
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            PSASFPP------------------------------------------A
MLBr_00048|M.leprae_Br4923          DAPLYPP------------------------------------------P
MMAR_5451|M.marinum_M               PGTAYPPPVKPNGDGHSAPKDWSRAFPPAEDESPSDSAEPAAGPAKSPLP
MAB_3131c|M.abscessus_ATCC_199      QGEFVKSASSTVEAPVARRLRESFGGG-DKPAPAASNG----AAAEAAAP
MUL_2122|M.ulcerans_Agy99           QGEFVKSASSTVEAPVARRLRESFGGGKSAPAKGSDTG----AAKGVAKA
MAV_4827|M.avium_104                -----------------------------------------------ATV
Rv3879c|M.tuberculosis_H37Rv        ------------------------------------------------WV
TH_4426|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          TPSSGATPPVPPSPG--------TPASTSTRGGTPPVPPAPPAPAGTPAS
Mvan_2552|M.vanbaalenii_PYR-1       RPSSGATPPVPPTPG--------TPASTTTGVGTPPVPPTPPGSTVRPAA
MSMEG_5381|M.smegmatis_MC2_155      ------MPPLPPAPG--------LDAP------LPPLPPEPAMASPRPWW
Mb3906|M.bovis_AF2122/97            PASANLPKPNGQTP---------PPTSDDLSERFVSAPPPP---------
MLBr_00048|M.leprae_Br4923          IIPTCTTTPNGEVA---------SPMPD-----WSEQLPPN---------
MMAR_5451|M.marinum_M               PMPIGGPAPTPPEP---------PPAPPELPPAPPEPPPARPEAPPQAPT
MAB_3131c|M.abscessus_ATCC_199      PKKAG---PKPGAP---------KPAPKKVAEPVVEAPVAPEPPAAPAAP
MUL_2122|M.ulcerans_Agy99           PQKVSGASPAAKAPDRSLDAALDKAVGNGAPAPVPAPAPAPTPAPAPAQP
MAV_4827|M.avium_104                EEDAIDVTGADDAAT--------ASAPDRVISAILGTREGAADAGLQLSS
Rv3879c|M.tuberculosis_H37Rv        EADEDTFYDRAQEYS---------QVLQRVTDVLDTCRQQKGHVFEGGLW
TH_4426|M.thermoresistible__bu      TELAGAAAPTDVVGR-------LRWTLHALDSDAPPAAQQLTVAAEDALR
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          GATP----------PAPPVPGVPAVTSTGGGTPPVPPVP-----------
Mvan_2552|M.vanbaalenii_PYR-1       GATP----------PAPPVPGVPAGTPIGGGTPPLPPVP-----------
MSMEG_5381|M.smegmatis_MC2_155      VALP----------PSPPAPAYDANPPL----PPAPAVA-----------
Mb3906|M.bovis_AF2122/97            --------------PPPPPPPPPTPMPIAAGEPPSPEP------------
MLBr_00048|M.leprae_Br4923          --------------PPAASKSPLPPMPIGSSVQPPP--------------
MMAR_5451|M.marinum_M               AEAEPPDEAIPVSGPPPGGKSPLPPMPIGGPPPASPEPP-----------
MAB_3131c|M.abscessus_ATCC_199      AAP-----------APKPSPAARPAAAEAAAPAPAPAP------------
MUL_2122|M.ulcerans_Agy99           ADSGV---------APPAATPAAPAASAAPAPPKAPLPGQRPAPTPGKPA
MAV_4827|M.avium_104                IGVT---------WTDQLEAAALRDALAARRIDNVMLVS-----------
Rv3879c|M.tuberculosis_H37Rv        SGGAAN--------AANGALGANINQLMTLQDYLATVITWHR--------
TH_4426|M.thermoresistible__bu      LGDLG----LCERFGRAAVGAAGSGAGLAARLPLAYALAFQG--------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------GAPVGAPVANPGLPTPPV
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------GAPAGTPVANVAPPSPPV
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------FAVEATLVMIASPPAPPL
Mb3906|M.bovis_AF2122/97            --------------------------------------AASKPPTPPMPI
MLBr_00048|M.leprae_Br4923          --------------------------------------ASSESPRAPMPV
MMAR_5451|M.marinum_M               -AAPPEPTAPAEPPQPPEAAAQPPQAVEEQAHATAEPPAAPNPPRPPMPI
MAB_3131c|M.abscessus_ATCC_199      ---APRPGATPGPKPG-----APRVPRVGNNPFSSAQPAERPAPRPQAPR
MUL_2122|M.ulcerans_Agy99           APQAPHPGMAPGARPGPVPKQGVRTPRVGNNPFSSAQPVDRPIPRPQAPR
MAV_4827|M.avium_104                --------------------------------------AFLAAAALAQNV
Rv3879c|M.tuberculosis_H37Rv        ---------------------------------HIAGLIEQAKSDIGNNV
TH_4426|M.thermoresistible__bu      ----------------------------RGREADEVLAAVDSTGLTEHEL
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          PGAPVFGDGGAVLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVA
Mvan_2552|M.vanbaalenii_PYR-1       PGVPVIGDGGAALPPLPPVPGGPAAVPAGVVTPPAPPIPGGPAAMPAGVA
MSMEG_5381|M.smegmatis_MC2_155      PGFELP------FPPFPPAPPVTVPRPADWAEPPLPPRP---TLSWPKLE
Mb3906|M.bovis_AF2122/97            AGPEPA-------------------------PPKPPTPPMPIAGPEPAPP
MLBr_00048|M.leprae_Br4923          SAP----------------------------PRSPAASLMPISEPPQWPP
MMAR_5451|M.marinum_M               GGPPPTPPAAPEPQQDIAEEPAPAAAEAPAAPPKSPLPPMPVSGPPPEPP
MAB_3131c|M.abscessus_ATCC_199      PGAPRP-----GGASPSNMPPRPSPGSMGPRPPRPGGGPRPGGGPRPGG-
MUL_2122|M.ulcerans_Agy99           PGAPRPGAPRPGGASSGNMPPRPGGASGGPRPPRTG-APRPGGG-RPGGP
MAV_4827|M.avium_104                GGAMGYER-----------------------TAVLLVEPDTATLAVVETS
Rv3879c|M.tuberculosis_H37Rv        DGAQREIDILENDPSLDADERHTAINSLVTATHGANVSLVAETAERVLES
TH_4426|M.thermoresistible__bu      MAWALPRAANQFWMLSQPERAVAFLRTVRERVSSPTAATTLDALSATFAM
                                     .                                                

Mflv_3843|M.gilvum_PYR-GCK          LPPAPPGAPGAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIGGPG
Mvan_2552|M.vanbaalenii_PYR-1       APPAP-APPGAPIFGEAGAVPPPGVGGAPLDGASGVAAPGGPGGGAGAPG
MSMEG_5381|M.smegmatis_MC2_155      LPPAP--------------------PVAAAAATAGAAGGGGRRRGVG--D
Mb3906|M.bovis_AF2122/97            KPP----------------------------------------TPPMPIA
MLBr_00048|M.leprae_Br4923          --------------------------------------------------
MMAR_5451|M.marinum_M               ELPPAPPE----PTASAEPPQPPQSVEEQAHATAEPPAAPKPTRPPMPIG
MAB_3131c|M.abscessus_ATCC_199      AGRPGGGGGGNYRGGGTGTGAPAGGPPGAGGGFRGRPGGGGGGGRPGQRG
MUL_2122|M.ulcerans_Agy99           GGGRSDGGGGNYRGGGGGVGAAPGG------GFRGRPGGGGGGGRPGQRG
MAV_4827|M.avium_104                DGSIP-------------------------DVYKQQIRAESYGDAAGQLS
Rv3879c|M.tuberculosis_H37Rv        KNWKP---------------------------------PKNALEDLLQQK
TH_4426|M.thermoresistible__bu      NAGRP--------------------QQALQTATEVLASPTADGTAIGWAG
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          GGGAPVEGTGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAP
Mvan_2552|M.vanbaalenii_PYR-1       APVAAAAGNAGPPAPGAPVGDQAGVVAPPAPPAPGAPVGDQAGLVAPPGP
MSMEG_5381|M.smegmatis_MC2_155      GGVAPVSAVAAVAVASAAVGDATDAAGDAAQPGGGG-----------VTA
Mb3906|M.bovis_AF2122/97            GPAPTPTESQLAP------------------------PRPPTPQTPTGAP
MLBr_00048|M.leprae_Br4923          AEAPEHQFAKAEP------------------------PSVPIPINEP-SP
MMAR_5451|M.marinum_M               GPPPTPEPQQGAPQPHQDIAEEPNPAAAEAPAAPPKSPRPPMPVNGP-AP
MAB_3131c|M.abscessus_ATCC_199      GAAGAFGRPGGAPKRGRKSKRAKRAEYENMQAPVVGGVRLPHGNGEVIRL
MUL_2122|M.ulcerans_Agy99           GAAGAFGRPGGAPRRGRKSKRAKRAEYENMQAPVVGGVRLPHGNGETIRL
MAV_4827|M.avium_104                AMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETAL
Rv3879c|M.tuberculosis_H37Rv        SPPPPDVPTLVVPSPGTPGTPGTPITPGTPITPGTPITPIPGAPVTPITP
TH_4426|M.thermoresistible__bu      AAAALSAARMGRFTEVDALAERAMSAGHPGLLRFTSGFGQTTARQLTGAP
                                    .                                                 

Mflv_3843|M.gilvum_PYR-GCK          PAPAPPAGGLGGAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGG
Mvan_2552|M.vanbaalenii_PYR-1       PAPGVPVVDQAGVVAPPGPPAPGVPVVDEAGVVTPPGPGAPGVPVVGEAG
MSMEG_5381|M.smegmatis_MC2_155      RAAVPSAAGRVKASAAPGAALAAGHIRCRFGVVD----------------
Mb3906|M.bovis_AF2122/97            QQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIG--EPP-PAP---SRPSA
MLBr_00048|M.leprae_Br4923          AKPATPMPMTPIDGSQRTPVTSPEPSLAEFEAQ--PPATPKPSLLPRPMS
MMAR_5451|M.marinum_M               TRPEPPLPPGPPRRRAQPPTAPPNQPGQPKPISGHPPPPPRPAAFAPPAR
MAB_3131c|M.abscessus_ATCC_199      ARGASLSDFAEKIDANPASLVQALFNLGEMVTATQSVGDETLELLGGEMN
MUL_2122|M.ulcerans_Agy99           ARGASLSDFADKINANPAALVQALFNLGEMVTATQSVGDETLELLGSEMN
MAV_4827|M.avium_104                ARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPG
Rv3879c|M.tuberculosis_H37Rv        TPGTPVTPVTPGKPVTPVTPVKPGTPGEPTPITPVTPPVAPATPATPATP
TH_4426|M.thermoresistible__bu      DQALALARRLTEIAQLQQPGRAIGELLIAEVLITRGDLDEAVALLRAAVK
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VV--------------TPPAPGAPGVPVVDEAGVVTPPAPGGPGVPTGGE
Mvan_2552|M.vanbaalenii_PYR-1       VV--------------TPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDE
MSMEG_5381|M.smegmatis_MC2_155      ---------------------GRVTAVAADATGAAFSGAPISSGATDRRR
Mb3906|M.bovis_AF2122/97            ---------------------SPAEPPTRP-----APQHSRRARRGHRYR
MLBr_00048|M.leprae_Br4923          ---------------------SPPEAPRPS-----ANQHSRHARRGHHHR
MMAR_5451|M.marinum_M               GATPNRHESAEPPPPRRVRIGGPPQPPGPPEAESEAPRHSRHARRTHRYR
MAB_3131c|M.abscessus_ATCC_199      ----------------YVVQVVSPEDEDRELLESFDLTYGEDEGGEEDLR
MUL_2122|M.ulcerans_Agy99           ----------------YNVQVVSPEDEDRELLESFDLTYGEDSGDESELQ
MAV_4827|M.avium_104                DD-------------------ELAYSAVGEEDAESPTVVIEKLFLPEDSE
Rv3879c|M.tuberculosis_H37Rv        VT-------------------PAPAPHPQPAPAPAPSPGPQPVTPATPGP
TH_4426|M.thermoresistible__bu      VLTP------------TGYSWAPLAAMLLARALGEQGAAPEAAIALSRAE
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          GGVVTPPAPGAPGAPVVDEAGVVTPPAPGGPGVPA-----VGDTAVVTPP
Mvan_2552|M.vanbaalenii_PYR-1       AGVVTPPGPGAPGVPVVDEAGVVTPPAPGAPGVPV-----DGGAELVTPP
MSMEG_5381|M.smegmatis_MC2_155      GRARRAGDGGVAAGTTVTGAGRVG------------------VTVAVTAV
Mb3906|M.bovis_AF2122/97            TDT-------ERNVGKVATGPSIQARLRAEEASGA-----QLAPGTEPSP
MLBr_00048|M.leprae_Br4923          DET-------QQANPASATEPMIAPRARTAELRQA-----P---------
MMAR_5451|M.marinum_M               PEP-------ETDDLEATAVRPLPTREPMRRNGPA-----ADES-STASF
MAB_3131c|M.abscessus_ATCC_199      TRPPVVTVMGHVDHGKTRLLDTIRKANVREGEAGG-----ITQHIGAYQV
MUL_2122|M.ulcerans_Agy99           TRPPVVTVMGHVDHGKTRLLDTIRKANVREGEAGG-----ITQHIGAYQV
MAV_4827|M.avium_104                PRR-------RPVLLVGSGLAVVGISAVLALEIAL-----AIGIRTTGTV
Rv3879c|M.tuberculosis_H37Rv        SGPATPGTPGGEPAPHVKPAALAEQPGVPGQHAGG-----GTQSGPAHAD
TH_4426|M.thermoresistible__bu      SRHGLKSMLFAPELALARAWTRAARGDRHGAVXXXXACWWWRWWDXXTPP
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          APGAPGTPAVNSVETFSPPAPPAATPPSSGSVETFSPPAPPAPGTGTNST
Mvan_2552|M.vanbaalenii_PYR-1       GPGAPGTPTVSSVETFSPPAPPAPGTPSSGSIETFSPPAPPTPGTPANSS
MSMEG_5381|M.smegmatis_MC2_155      AAGAAQC-------------------------------------------
Mb3906|M.bovis_AF2122/97            APLGQPRSYLAPPTRPAPTEP-PPSPSPQRNSGRRAERRVHPDLAAQHAA
MLBr_00048|M.leprae_Br4923          ---------------HAAAEP-APTQHLTR-----------PDGLVSHRT
MMAR_5451|M.marinum_M               AWLQQSQPTLDRPSGPMPAAPGAPVESAPG----------RADGRRARRR
MAB_3131c|M.abscessus_ATCC_199      AVEHDGTERPITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQT
MUL_2122|M.ulcerans_Agy99           SVDHDGTERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQT
MAV_4827|M.avium_104                ALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVAA
Rv3879c|M.tuberculosis_H37Rv        ESAASVTPAAASGVPGARAAAAAPSGTAVGAGARSSVGTAAASGAGSHAA
TH_4426|M.thermoresistible__bu      GPPAPPAGGGGGGDVETPPGPPAPPAEVEERDDAEIPPGPPSPPAGGGGG
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VEISTPPPPGTPGLPSEGSTTYTTPPTPEITLNPANSGIDIATPPAPGLP
Mvan_2552|M.vanbaalenii_PYR-1       VEIVTPPPPGVPGVPGEGSTTYTTPPTPEITLNPANSSIDVATPPGPGVP
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            AQPDSITAATTGGRRRKRAAPDLDATQKSLRPAAKGPKVKKVKPQK----
MLBr_00048|M.leprae_Br4923          ALHDSTATSAIG-------------VQTGRSTGAK---------------
MMAR_5451|M.marinum_M               AESRTSAASTPSPLVPTRAQPPGPTRAQPPRTAAPAQPATEPLPDAGAPA
MAB_3131c|M.abscessus_ATCC_199      VEAINHAQAADVPIVVAVNKIDKEGADPAKIRAQLTEYNLVAEDFGGDTM
MUL_2122|M.ulcerans_Agy99           VEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTM
MAV_4827|M.avium_104                PLPAAPPPAAPP-----------LPEAPPIPAAPPVVPVPVVVPPVPVPV
Rv3879c|M.tuberculosis_H37Rv        TGRAPVATSDKAAAPSTRAASARTAPPARPPSTDHIDKPDRSESADDGTP
TH_4426|M.thermoresistible__bu      GEIAPPPTPGEPGAVIDQSSQNVTVPAPPTPGSETSTALEVFSPPVP---
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          GAPLEATANITTPGTPGVPGAPVNSSIDVATPGEVGVPAAPIERSMTVTT
Mvan_2552|M.vanbaalenii_PYR-1       GVPVEASANVSTPPVPGVPGAPVNSSVEVATPAEVGVPGTPIERSTTLTT
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            PKATKPPKVVSQRGWRHWVHALTRINLGLSPDEKYELDLHARVR------
MLBr_00048|M.leprae_Br4923          ----KPSKVVAKRGWRHWVHTVTRINLGLSPDERYELDLRTRVR------
MMAR_5451|M.marinum_M               EQSKKPNKPVPQRGWRRWVYAVTRINFGLSPDEKYELDLRTRIG------
MAB_3131c|M.abscessus_ATCC_199      FVDISARQGTNIEQLLEAVLLTADAALDLRANPDMEAQGVAIEA------
MUL_2122|M.ulcerans_Agy99           FVDISAKQGTNIEALEEAVLLTADAALDLRANPDMEAQGVAIEA------
MAV_4827|M.avium_104                PVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGG------
Rv3879c|M.tuberculosis_H37Rv        VSMIPVSAARAARDAATAAASARQRGRGDALRLARRIAAALNAS------
TH_4426|M.thermoresistible__bu      ----PGEVSGGGSNMLELPGFPGGTIGGPEIAHNVEVTGPPAEAS-----
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          PDTPGAPGAPANAAVDVATPPAPGVPGAPVVGEAGVTTPGAPGAPGAPAN
Mvan_2552|M.vanbaalenii_PYR-1       PPTPGVPGTPVNSSVEVATPPAPGAPGVPVVDEAGVVTPPGPGAPGVPVV
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            ----RNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVR---------AD
MLBr_00048|M.leprae_Br4923          ----RPPRGSYQIGILGLKGGAGKTTVTVTLGSMFARVR---------ND
MMAR_5451|M.marinum_M               ----RKPRGSYQIAILGLKGGAGKTTTTVTLGTTLTHVR---------GD
MAB_3131c|M.abscessus_ATCC_199      ----HLDRGRGPVATVLIQRGTLRVGDSIVAGDAYGRVRRMVDEHGEDVE
MUL_2122|M.ulcerans_Agy99           ----HLDRGRGPVATVLVQRGTLRVGDSVVAGDAYGRVRRMVDEHGEDVE
MAV_4827|M.avium_104                ----TVPQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPG----------
Rv3879c|M.tuberculosis_H37Rv        ----DNNAGDYGFFWITAVTTDGSIVVANSYGLAYIPDG-----------
TH_4426|M.thermoresistible__bu      -----VPGVDASVATEAGTPPVPPGPTAPIEHAAETSVPAEVEIPGAEID
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          AAVDVATPPAPGVPGAPVVGEAAVTTPGAPGVPGVPAGGDAGVVTPPAPG
Mvan_2552|M.vanbaalenii_PYR-1       GEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPG
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            RILALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAV
MLBr_00048|M.leprae_Br4923          RILVVDADTSCGNLADRAGRFSEANIADLLADKDVKSYNDIRTHTSVNAV
MMAR_5451|M.marinum_M               RILVLDADPGAGNLAERSGRSSPSSIADLLADPRLSHYNDVRAHTSVNAA
MAB_3131c|M.abscessus_ATCC_199      EALPSRPVQVIGFTSVPGAGDNLLVVDEDRIARQIADRRSARKRNALAAR
MUL_2122|M.ulcerans_Agy99           EALPSRPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAAR
MAV_4827|M.avium_104                --AGGSGGSGGGHVPTPGAGGSGGSGGGHVPTPGTGGPGGTGGSGGGHVP
Rv3879c|M.tuberculosis_H37Rv        MELPNKVYLASADHAIPVDEIARCATYPVLAVQAWAAFHDMTLRAVIGTA
TH_4426|M.thermoresistible__bu      HRAEVATPPVDGPPVEVENSVEVATPPHXXGPGAVVDXX----XXRRPGA
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VPGAPVVGEAGVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPAATEAGL
Mvan_2552|M.vanbaalenii_PYR-1       APGVPVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGV
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            NLEVLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTR
MLBr_00048|M.leprae_Br4923          NLEVLPAAEYSTAQHALSGEDWNFAAATVSKYYNVMLADCGVGLFDPVTR
MMAR_5451|M.marinum_M               NLEILPTAEYTSAQRGLSGEDLRSAVDTVSKFYNLVLADCGAGLFDPVTL
MAB_3131c|M.abscessus_ATCC_199      SRKRISLDDLDAALKETSQLNLILKGDNAGTVEALEEALLGIAIDDEVQL
MUL_2122|M.ulcerans_Agy99           SRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIEVDDEVAL
MAV_4827|M.avium_104                TPGAGTPGGSGGGHLPFPGAGSTPGGSGGGHLPTPGAGTPGGGLGGFGGG
Rv3879c|M.tuberculosis_H37Rv        EQLASSDPGVAKIVLEPDDIPESGKMTGRSRLEVVDP-SAAAQLADTTDQ
TH_4426|M.thermoresistible__bu      DPRPXPLPVAAQLHPRPVGCDGPRRPHRGGVVTASRQPRRLTGRVDAPHL
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          ATPPGPGAPGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAP-----V
Mvan_2552|M.vanbaalenii_PYR-1       VTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPAPPAAAPG
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            GVLSTVSG-----------------------VVVVASVSIDGAQQASVAL
MLBr_00048|M.leprae_Br4923          GVLSTASG-----------------------VVIVTSTSVDAARQAAIAL
MMAR_5451|M.marinum_M               GVLDTASA-----------------------IVILTNVSIDSARQAAIAL
MAB_3131c|M.abscessus_ATCC_199      RVIDRGVG-----------------------GVTETNVNLASASDAIIIG
MUL_2122|M.ulcerans_Agy99           RVIDRGVG-----------------------GITETNVNLASASDAIIIG
MAV_4827|M.avium_104                HAPAPGGG-------------------------LGGGGGHAPAPGGGLGG
Rv3879c|M.tuberculosis_H37Rv        RLLDLLPP---------------------------APVDVNPPGDERHML
TH_4426|M.thermoresistible__bu      HRHRGQPG--------------------------DAQHQHGHHRRQRERG
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          APVEGAGGAVPPAGPPPAPVFGDAGAPVEAAAGGAPVEAAAGVTGGGSVA
Mvan_2552|M.vanbaalenii_PYR-1       APIDAAAASVAPSGPPAAPVLGEAGVVAPPAP-----------PGGGAPG
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            DWLRNNG-YQDLASRACVVIN-----------------------------
MLBr_00048|M.leprae_Br4923          DWLRHNG-YQDLLSRACVVIN-----------------------------
MMAR_5451|M.marinum_M               DWLRKHG-YQDLASRACVAIN-----------------------------
MAB_3131c|M.abscessus_ATCC_199      FNVRAEGKATELANREGVDIRYYS--------------------------
MUL_2122|M.ulcerans_Agy99           FNVRAEGKATELANREGVEIRYYS--------------------------
MAV_4827|M.avium_104                FGGGHSGGGLGGLGGGHK--------------------------------
Rv3879c|M.tuberculosis_H37Rv        WFELMKPMTSTATGREAAHLRAFR--------------------------
TH_4426|M.thermoresistible__bu      FHGDRATITHTLVFNAR---------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          GAGAGGGAGGAAGGAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGGAPGG
Mvan_2552|M.vanbaalenii_PYR-1       GGAPGAGVG---TGAPIEGAAGAGGVPAAPLAANAGAAT---PPAAATGG
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            --------------------------------------------------
MLBr_00048|M.leprae_Br4923          --------------------------------------------------
MMAR_5451|M.marinum_M               --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_2122|M.ulcerans_Agy99           --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          PVAGGGPVGGPGALPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPP
Mvan_2552|M.vanbaalenii_PYR-1       ----------------AGAPIDAAAGAAAPPAP----------------P
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            --------------------------------------------------
MLBr_00048|M.leprae_Br4923          --------------------------------------------------
MMAR_5451|M.marinum_M               --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_2122|M.ulcerans_Agy99           --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          APGVPGAPVFGEAGVVTPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVP
Mvan_2552|M.vanbaalenii_PYR-1       AP---GAPIFGEAGVAAPPLPPAPGGAGAVPAGVVTPPVPGVPGGAGAVP
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            --------------------HIMPGEPNVAVKDLVRHFEQQVQPGRVVVM
MLBr_00048|M.leprae_Br4923          --------------------HVMPKEPNIASKDLVQQFEQQIQPGRVVVL
MMAR_5451|M.marinum_M               --------------------HVAVGETNVSEQQLVRDFEQQLQPGRVVVL
MAB_3131c|M.abscessus_ATCC_199      ------------------VIYQAIDEIESALKGMLKPVYEEVELGRAEIR
MUL_2122|M.ulcerans_Agy99           ------------------VIYQAIDEIEKALRGMLKPIYEEVELGRAEIR
MAV_4827|M.avium_104                --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv        --------------------AYAAHSQEIALHQAHTATDAAVQR------
TH_4426|M.thermoresistible__bu      ---------------------LMMLVSALTIESPVTTAYRMAPNAAAAIV
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          AGAVTPPAPGVPGAPVFGDAGVATPPVPGVPGGGTTVPAASVTPPAPGVP
Mvan_2552|M.vanbaalenii_PYR-1       AGAVTPPTP----------------PVPGSSSGG----------------
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            PWDRH---------------------------------------------
MLBr_00048|M.leprae_Br4923          PWDKH---------------------------------------------
MMAR_5451|M.marinum_M               PWDRH---------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      AMFRS---------------------------------------------
MUL_2122|M.ulcerans_Agy99           ALFRS---------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_4426|M.thermoresistible__bu      PTAYS---------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          GGASTVPGNAGTPSTPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPG
Mvan_2552|M.vanbaalenii_PYR-1       -------------------------FVNYPAPPVPPTPPNSAGVNTGTPG
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            --------------------------------------------------
MLBr_00048|M.leprae_Br4923          --------------------------------------------------
MMAR_5451|M.marinum_M               --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_2122|M.ulcerans_Agy99           --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          SPAPGTPGSTLTLTDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGS
Mvan_2552|M.vanbaalenii_PYR-1       SPIPGTPGSTLTISDLLTPPGVARTVQNTASSVMSIAPPGTPPVPGGAGS
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            -IAAGTEISLDLLDPIYKR----KVLELAAALSDDFERAGRR--------
MLBr_00048|M.leprae_Br4923          -IAAGTEIRLDRLDPLYRR----RILELAAALSDDFERAGRH--------
MMAR_5451|M.marinum_M               -IAAGTEIHLDQLGPVYRR----RVLELAAALSDDFERAGRR--------
MAB_3131c|M.abscessus_ATCC_199      -SKVGNIAGCLVTSGIIRRNAKARLLRDNIVVAETVTISSLRREKDDVVE
MUL_2122|M.ulcerans_Agy99           -SKVGLIAGCMISSGVVRRNAKARLLRDNIVVVENLSIRSLRREKDDVTE
MAV_4827|M.avium_104                --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv        ----------VAVADWLYWQYVTGLLDRALAAAC----------------
TH_4426|M.thermoresistible__bu      ------------------------TVDIPASSTINIVVLA----------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VSLAVPGTPSPIAPLAATGLSNLVSPPSLTIPSIPGLPVPLPNTVPVPSD
Mvan_2552|M.vanbaalenii_PYR-1       VSVGVPAPPSPLTPLAATGLSNLVSPPSLTIPSIPGLPVPLPNEVPVPSD
MSMEG_5381|M.smegmatis_MC2_155      --------------------------------------------------
Mb3906|M.bovis_AF2122/97            --------------------------------------------------
MLBr_00048|M.leprae_Br4923          --------------------------------------------------
MMAR_5451|M.marinum_M               --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      VRDGYECGLTLTYNDIKEGDVIEAYELREKERV-----------------
MUL_2122|M.ulcerans_Agy99           VREGFECGMTLGYSDLKEGDFIESYELVQKDRS-----------------
MAV_4827|M.avium_104                --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          LLCVGTDWSASQGDSAATPPAAEVPR-VVTGAAPTGDRRDRWGNR
Mvan_2552|M.vanbaalenii_PYR-1       LLCVGTDWSATQGDSATTPVNAEIPRALVTGAAPVGDRRDRWDTR
MSMEG_5381|M.smegmatis_MC2_155      ---------------------------------------------
Mb3906|M.bovis_AF2122/97            ---------------------------------------------
MLBr_00048|M.leprae_Br4923          ---------------------------------------------
MMAR_5451|M.marinum_M               ---------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      ---------------------------------------------
MUL_2122|M.ulcerans_Agy99           ---------------------------------------------
MAV_4827|M.avium_104                ---------------------------------------------
Rv3879c|M.tuberculosis_H37Rv        ---------------------------------------------
TH_4426|M.thermoresistible__bu      ---------------------------------------------