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GTLSYSTTISIDGYVNDADGDFQWSAPSDPVFDTHVERMAAVSTEVLGRKTYELMRYWETDHHDFSPAEE EFARRWRKIQKVVVSSTLTPDHVAAGRDRLVPRLDLDELRKIVADATGTVEIFGPTTAAPAIRAGMVDEF NFFVVPKVVGGGLRALPDDVRLDLGLAEHTIFDDGVVYLRYAPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5219 | - | - | 100% (185) | riboflavin biosynthesis protein RibD domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0308 | - | 3e-06 | 25.16% (159) | dihydrofolate reductase |
| M. smegmatis MC2 155 | MSMEG_3067 | ribD | 3e-05 | 25.61% (164) | riboflavin biosynthesis protein RibD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3231 | - | 2e-25 | 37.10% (186) | deaminase-reductase domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00555 | ribG | 3e-05 | 27.45% (153) | putative bifunctional riboflavin-specific |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3368 | ribD | 1e-06 | 26.25% (160) | riboflavin biosynthesis protein RibD |
| M. thermoresistible (build 8) | TH_2924 | - | 8e-10 | 42.86% (77) | PUTATIVE bifunctional deaminase-reductase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4641 | - | 4e-07 | 27.53% (178) | deaminase-reductase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3231|M.gilvum_PYR-GCK --------------------------------------------------
TH_2924|M.thermoresistible__bu --------------------------------------------------
MSMEG_5219|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00555|M.leprae_Br4923 MNVQTVDSLDAAMRLAVEQSYLVKGATYPNPPVGAVIVDPDGRVVGVGAT
MAV_3368|M.avium_104 MTASLGDRLDAAMRLAIEQSNQVKGNTYPNPPVGAVVLDGRGEVVGVGGT
Mvan_4641|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3231|M.gilvum_PYR-GCK ---------MSAARRGSLKSMGKLIYGFNVSVDGYIADARGSIDWSDPND
TH_2924|M.thermoresistible__bu --------------------------------------------------
MSMEG_5219|M.smegmatis_MC2_155 --------------------MGTLSYSTTISIDGYVNDADGDFQWSAPSD
MLBr_00555|M.leprae_Br4923 EPAGGDHAEVVALRSAGVTAAGAIAVVTLEPCNHYGKTPPCVNALLEAKV
MAV_3368|M.avium_104 EPAGGDHAEILALRRAGDLAAGGTVVVTLEPCNHHGKTPPCVDALLEAGV
Mvan_4641|M.vanbaalenii_PYR-1 --------------------MRKLTAGLFIALDG-VVEAPDQWHFPYFDD
Mflv_3231|M.gilvum_PYR-GCK EVHQYWNDFERDTALAFYGRRLYDLMSDYWPTADEDPDATPLIVDFARIW
TH_2924|M.thermoresistible__bu --------------------------------------------------
MSMEG_5219|M.smegmatis_MC2_155 PVFDTHVERMAAVSTEVLGRKTYELMR---YWETDHHDFSPAEEEFARRW
MLBr_00555|M.leprae_Br4923 DKVAYAIADPNASAGGGAARLTAAGVHVQSGVLADLVTAGPLREWLHKQR
MAV_3368|M.avium_104 STVVYAVADPNPQAAGGAGRLQEAGVTVRSGLLADEVSGGPLREWLHKQR
Mvan_4641|M.vanbaalenii_PYR-1 AMGEAVNAQLGSADTLLLGRVTYDSFAGAWPLREAE---GGEDAEFAKAL
Mflv_3231|M.gilvum_PYR-GCK RDMPKVVFSR-TLESVDWNSRLERGDP---VEVVT----KLKAETDGQLE
TH_2924|M.thermoresistible__bu --MPKVVFSR-TLETVDWNSRLERGDP---VEMVR----KVKAETDGTLE
MSMEG_5219|M.smegmatis_MC2_155 RKIQKVVVSS-TLTPDHVAAGRDRLVPRLDLDELR----KIVADATGTVE
MLBr_00555|M.leprae_Br4923 TGLPHVTWKY-ASSIDGRSAAADGSSRWLSSEASRADLHRRRATADAIVV
MAV_3368|M.avium_104 TGLPHLTWKY-ASSVDGRSAAADGSSRWISSEASRLDLHRRRAAADAIVV
Mvan_4641|M.vanbaalenii_PYR-1 GDARKIVVSRQDLRFSWRNSEQLTGDLVEAVTALK------NGPGDGDIA
::. . : . . :
Mflv_3231|M.gilvum_PYR-GCK VAGATLAA-PIVQAGLVDEYRIVVSPVAVGGGLPFFPNLPSWISLRLLEN
TH_2924|M.thermoresistible__bu VAGATLAA-PIVLAGLVDEFRMVMAPIVVGGGTRFFPTVPSWISLRLSEK
MSMEG_5219|M.smegmatis_MC2_155 IFGPTTAA-PAIRAGMVDEFNFFVVPKVVGGGLRALP-DDVRLDLGLAEH
MLBr_00555|M.leprae_Br4923 GTGTVLADNPTLTARLANGALADRQPLRVVVGMREIPLEANVLNDDSPTM
MAV_3368|M.avium_104 GTGTVLADDPALTARLPDGTLADRQPLRVVVGMREIPSEAKVLNDDSRTM
Mvan_4641|M.vanbaalenii_PYR-1 MSGSPSVVRQLLQAGLVDELHLLVHPIAVRKGARLFDEGTPIPLKLLTSN
*. . : * : : * * * :
Mflv_3231|M.gilvum_PYR-GCK RTFPG--GTVLLRYEARRD-------------------------------
TH_2924|M.thermoresistible__bu PHFSRRHGPAALRGETRLMAGLVRAIRRRPGSNPPGELNVILTQWASDFV
MSMEG_5219|M.smegmatis_MC2_155 TIFDD--GVVYLRYAPG---------------------------------
MLBr_00555|M.leprae_Br4923 VIRTHDPMEVLKALADRTDVLLEGGPTLAGAFLRAGTINRILAYVAPILL
MAV_3368|M.avium_104 VIRTHDPAEVLKAVSDRTDVLLEGGPTLAGAFVRAGLVNRILVYLAPTLL
Mvan_4641|M.vanbaalenii_PYR-1 TFDTGVVHLVYTRDDQTRSGGYEDAKSHL---------------------
.
Mflv_3231|M.gilvum_PYR-GCK ------------------------------------------
TH_2924|M.thermoresistible__bu GAAIEFDHTVAPP-------WRWYRTASAES-----------
MSMEG_5219|M.smegmatis_MC2_155 ------------------------------------------
MLBr_00555|M.leprae_Br4923 GGPVTAVDDVGVPNIARALRWQFDGIDRAGSDLVISLVTR--
MAV_3368|M.avium_104 GGPVTAVDDVGVPTIAKALRWQFDGVDRVGPDLLLSLVPRSG
Mvan_4641|M.vanbaalenii_PYR-1 ------------------------------------------