For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MLAVEQPTERMLELYANHVDPLRRYAFRLTSNQTRSEDIVQETFLRAWRHLQNNDGDLPLRSWLFTVARN IVIDGSRSARVRYEVSSPDTPEVPDRMGADEVNAALDRILVAEAMAQLPESHRAVLSRSFYLGWTTGRIA EDLGIAEGTVKSRLHYSLKRLRLILAEMGCHARS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5214 | - | - | 100% (174) | RNA polymerase sigma-70 factor |
| M. smegmatis MC2 155 | MSMEG_1486 | - | 3e-42 | 50.85% (177) | RNA polymerase sigma factor SigL |
| M. smegmatis MC2 155 | MSMEG_5072 | - | 2e-15 | 33.93% (168) | RNA polymerase sigma factor SigE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0756 | sigL | 9e-47 | 57.50% (160) | RNA polymerase sigma factor SigL |
| M. gilvum PYR-GCK | Mflv_5019 | - | 1e-44 | 56.25% (160) | RNA polymerase sigma factor SigL |
| M. tuberculosis H37Rv | Rv0735 | sigL | 9e-47 | 57.50% (160) | RNA polymerase sigma factor SigL |
| M. leprae Br4923 | MLBr_01076 | sigE | 4e-13 | 33.54% (158) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_2163 | - | 2e-35 | 48.12% (160) | ECF subfamily RNA polymerase sigma factor |
| M. marinum M | MMAR_1073 | sigL | 4e-46 | 58.13% (160) | alternative RNA polymerase sigma factor (RpoE), SigL |
| M. avium 104 | MAV_4431 | - | 3e-48 | 59.38% (160) | RNA polymerase sigma factor SigL |
| M. thermoresistible (build 8) | TH_0545 | sigE | 9e-15 | 35.44% (158) | ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGE |
| M. ulcerans Agy99 | MUL_0831 | sigL | 5e-45 | 56.88% (160) | RNA polymerase sigma factor SigL |
| M. vanbaalenii PYR-1 | Mvan_1350 | - | 8e-46 | 54.17% (168) | RNA polymerase sigma factor SigL |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0756|M.bovis_AF2122/97 --------------------------------------------------
Rv0735|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4431|M.avium_104 --------------------------------------------------
MMAR_1073|M.marinum_M --------------------------------------------------
MUL_0831|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5019|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1350|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2163|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5214|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01076|M.leprae_Br4923 MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSPT
TH_0545|M.thermoresistible__bu ---------------------------------------------MSVPA
Mb0756|M.bovis_AF2122/97 ----------------------MARVSGAA-AAEAALMRALYDEHAAVLW
Rv0735|M.tuberculosis_H37Rv ----------------------MARVSGAA-AAEAALMRALYDEHAAVLW
MAV_4431|M.avium_104 ----------------------MVGISRASGTAEAALMKALYDEHAAVLW
MMAR_1073|M.marinum_M ----------------------MARVAGGG-AAEAALMQALYDEHAAVLW
MUL_0831|M.ulcerans_Agy99 ----------------------MARVAGGG-AAEAALMQALYDEHAAVLW
Mflv_5019|M.gilvum_PYR-GCK ----------------------ME-------DADAAMMRVLYDEHAAALW
Mvan_1350|M.vanbaalenii_PYR-1 ----------------------MD-------DPEAAMMRVLYDEHAAALW
MAB_2163|M.abscessus_ATCC_1997 -------------------------------------MRAFYDEYAGPLH
MSMEG_5214|M.smegmatis_MC2_155 ---------------------------MLAVEQPTERMLELYANHVDPLR
MLBr_01076|M.leprae_Br4923 IMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARVY
TH_0545|M.thermoresistible__bu SMTHFAPPQATEWAEPVEEPTGTAVFDATGDKSTMPSWDELVRQHADRVY
: ::. :
Mb0756|M.bovis_AF2122/97 RYALRLTGDAAQAEDVVQETLLRAWQHPEVIGDTARPARAWLFTVARNMI
Rv0735|M.tuberculosis_H37Rv RYALRLTGDAAQAEDVVQETLLRAWQHPEVIGDTARPARAWLFTVARNMI
MAV_4431|M.avium_104 RYALRLTGDASQSEDVVQETLLRAWQHPEVIGDTERSARAWLFTVARNMI
MMAR_1073|M.marinum_M RYAMRLTSDASYADDIVQETLLRAWQHPEVIDERGRSARAWLFTVARNMI
MUL_0831|M.ulcerans_Agy99 RYTMRLTSDASYADDIVQETLLRAWQHPEVIDERGRSARAWLFTVARNMI
Mflv_5019|M.gilvum_PYR-GCK RYALRLTGDRARSEDVVQETLLRAWRHPGVIADVDRPARAWLFTVARNMI
Mvan_1350|M.vanbaalenii_PYR-1 RYALRLTGDRARAEDVVQETLLRAWRHPEVTADVDRSARAWLFTVARNMI
MAB_2163|M.abscessus_ATCC_1997 RYVMHLTHDSALAEDIVQEVLLRAWRHPTLVNQTEGSARAWLFTVAHNLV
MSMEG_5214|M.smegmatis_MC2_155 RYAFRLTSNQTRSEDIVQETFLRAWRHLQ-NNDGDLPLRSWLFTVARNIV
MLBr_01076|M.leprae_Br4923 WLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPG--TFEGWLHRITTNLF
TH_0545|M.thermoresistible__bu RLAYRLSGNQHDAEDLTQETFIRVFRSLQNYQPG--TFEGWLHRITTNLF
. :*: : ::*:.**.::*.:: . ..**. :: *:.
Mb0756|M.bovis_AF2122/97 IDERRS-ARFRNVVGSTDQSGTPEQSTPDE--VNAALDRLLIADALAQLS
Rv0735|M.tuberculosis_H37Rv IDERRS-ARFRNVVGSTDQSGTPEQSTPDE--VNAALDRLLIADALAQLS
MAV_4431|M.avium_104 IDDRRS-ARFRNVVGSTDTAGAPEQSTPDE--VNAALDRLLIADAMAQLS
MMAR_1073|M.marinum_M IDDRRS-ARYRYVVSSTDADGAPEQSTPDE--VGAALDRLLIADALAQLS
MUL_0831|M.ulcerans_Agy99 IDDRRS-ARYRYVVSSTDADGAPEQSTPDE--VGAALGRLLIADALAQLS
Mflv_5019|M.gilvum_PYR-GCK IDERRS-ARFRHETGVPDPEHVAEPASPDE--ADPTLDRILLGTALRQLS
Mvan_1350|M.vanbaalenii_PYR-1 IDERRS-ARFKHESGVADTEYVPDSASPDE--ADTALDRILLSTALSQLS
MAB_2163|M.abscessus_ATCC_1997 RDNARS-SRFRSEIATAET---PEFASPDQ--VDATLDAWLVAEALRTLS
MSMEG_5214|M.smegmatis_MC2_155 IDGSRS-ARVRYEVSSPDTPEVPDRMGADE--VNAALDRILVAEAMAQLP
MLBr_01076|M.leprae_Br4923 LDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPDLQAALDSLP
TH_0545|M.thermoresistible__bu LDMVRRRGRIRMESLPEDYDRVPGNSPNPEQIYHDARLGPDLQAALDSLP
* * .* : : . : : : *: *.
Mb0756|M.bovis_AF2122/97 AEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRALRLTLQELG
Rv0735|M.tuberculosis_H37Rv AEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRALRLTLQELG
MAV_4431|M.avium_104 AEHRAVIERSYYRGWTTAQIATDLGIAEGTVKSRLHYAVRALRLTLQELG
MMAR_1073|M.marinum_M GEHRAVIERSYYRGWTTAQIAKDLEIAEGTVKSRLHYAVRALRLTLQELG
MUL_0831|M.ulcerans_Agy99 GEHRAVIERSYYRGWTTAQIAKDLEIAEGTVKSRLHYAVRALRLTLQELG
Mflv_5019|M.gilvum_PYR-GCK DEHRAVVRRAYYQGWTTGQIAADLQIPEGTVKSRLHYAVRALKLGLQEMG
Mvan_1350|M.vanbaalenii_PYR-1 DEHRAVVRRAYYQGWTTGQIAADLNIPEGTVKSRLHYAVRALKLGLQEMG
MAB_2163|M.abscessus_ATCC_1997 TDHRAVILRAYYRGSSVADISAELGVPEGTVKSRLHYGVRALRLSLQEMG
MSMEG_5214|M.smegmatis_MC2_155 ESHRAVLSRSFYLGWTTGRIAEDLGIAEGTVKSRLHYSLKRLRLILAEMG
MLBr_01076|M.leprae_Br4923 PEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLLTAH
TH_0545|M.thermoresistible__bu PDFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLARHS
..**.: . * : *. * : ***:**:* . : *: *
Mb0756|M.bovis_AF2122/97 VTR------------
Rv0735|M.tuberculosis_H37Rv VTR------------
MAV_4431|M.avium_104 VTR------------
MMAR_1073|M.marinum_M VTR------------
MUL_0831|M.ulcerans_Agy99 VTR------------
Mflv_5019|M.gilvum_PYR-GCK VTR------------
Mvan_1350|M.vanbaalenii_PYR-1 VTR------------
MAB_2163|M.abscessus_ATCC_1997 VTR------------
MSMEG_5214|M.smegmatis_MC2_155 CHARS----------
MLBr_01076|M.leprae_Br4923 PRDGATTDATHVKSA
TH_0545|M.thermoresistible__bu QNSGQSATTS-----