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PHGVVDVPELITVARGGSMRAVGRLLTLVESDRRGEVLAALGPATPRVIGVTGPPGAGKSTTVGAMVGAY RERGLRVAVLAVDPSSPYSGGALLGDRIRMAAHINDPDVLIRSMAARGHLGGLAAAVPAAIRLLAALSYD LIVLETVGVGQSEIEIAAIADPTVVILNPGAGDAVQAAKAGVLEVADLVVVNKADRDGADQTVRDLRAET DVPVLKLVAAQGDGLHELIEAIEAHQRADTPERRRARARSQILSLAQTLLRNHADLDRLSAAVADGSSDA YTAAERLFAGSVD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_4869 | - | - | 100% (294) | LAO/AO transport system ATPase |
M. smegmatis MC2 155 | MSMEG_3160 | - | 5e-43 | 40.42% (287) | arginine/ornithine transport system ATPase |
M. smegmatis MC2 155 | MSMEG_2430 | ffh | 3e-06 | 27.23% (202) | signal recognition particle protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1533 | - | 1e-42 | 41.05% (285) | arginine/ornithine transport system ATPase |
M. gilvum PYR-GCK | Mflv_2397 | - | 1e-128 | 82.81% (285) | LAO/AO transport system ATPase |
M. tuberculosis H37Rv | Rv1496 | - | 1e-42 | 41.05% (285) | arginine/ornithine transport system ATPase |
M. leprae Br4923 | MLBr_01798 | - | 4e-42 | 39.65% (285) | arginine/ornithine transport system ATPase |
M. abscessus ATCC 19977 | MAB_2710c | - | 1e-39 | 37.59% (282) | putative kinase ArgK |
M. marinum M | MMAR_4787 | - | 1e-111 | 70.49% (288) | transport system kinase |
M. avium 104 | MAV_0871 | - | 1e-115 | 74.65% (288) | LAO/AO transport system ATPase |
M. thermoresistible (build 8) | TH_0131 | - | 1e-124 | 81.18% (287) | LAO/AO transport system ATPase |
M. ulcerans Agy99 | MUL_0356 | - | 1e-111 | 69.79% (288) | transport system kinase |
M. vanbaalenii PYR-1 | Mvan_4250 | - | 1e-123 | 80.28% (284) | LAO/AO transport system ATPase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2397|M.gilvum_PYR-GCK -------------------------------MTVEELIAAARGGSARATG Mvan_4250|M.vanbaalenii_PYR-1 MKRSLSSKENIILDNGRVLRRGGARLRTLCEVTIEELIAAARGGSQRATG MSMEG_4869|M.smegmatis_MC2_155 --------------------------MPHGVVDVPELITVARGGSMRAVG TH_0131|M.thermoresistible__bu -------------------------------MNIHELVTAARSGSIRAAG MMAR_4787|M.marinum_M -------------------------------MSIDDLIAAARNGSQRAAG MUL_0356|M.ulcerans_Agy99 -------------------------------MSIDDLIAAARNGSQRAAG MAV_0871|M.avium_104 -------------------------------MTIGELIDRARNGSPRAAG Mb1533|M.bovis_AF2122/97 -----------------------MMAASHDDDTVDGLATAVRGGDRAALP Rv1496|M.tuberculosis_H37Rv -----------------------MMAASHDDDTVDGLATAVRGGDRAALP MLBr_01798|M.leprae_Br4923 ------------------------MAG---DSTVDRLVAAVRSGDRVALP MAB_2710c|M.abscessus_ATCC_199 ------------------------MSAP------DNLAALIRSGDRSGLA * *.*. . Mflv_2397|M.gilvum_PYR-GCK RLLSYVESPRREA------VLAALG--SVAPARVVGITGPPGAGKSTTVG Mvan_4250|M.vanbaalenii_PYR-1 RLLSFVESPRRDE------VLDALG--DLLPAQVVGITGPPGAGKSTTVG MSMEG_4869|M.smegmatis_MC2_155 RLLTLVESDRRGE------VLAALG--PATP-RVIGVTGPPGAGKSTTVG TH_0131|M.thermoresistible__bu RLLSLVEGPRRDE------VLAALG--ETAPPRVIGITGPPGAGKSTTVG MMAR_4787|M.marinum_M RLLSLIEGDRRDE------VLAGIEDWSQRPARVIGITGPPGAGKSTTIT MUL_0356|M.ulcerans_Agy99 RLLSLIEGDRRDE------VLAGIEDWSQRPARVIGITGPPGAGKSTTIT MAV_0871|M.avium_104 RLLSLVEGEQRDE------VLTAIGPAPRDTGPVIGITGPPGAGKSTTVA Mb1533|M.bovis_AF2122/97 RAITLVESTRPDHREQAQQLLLRLLP-DSGNAHRVGITGVPGVGKSTAIE Rv1496|M.tuberculosis_H37Rv RAITLVESTRPDHREQAQQLLLRLLP-DSGNAHRVGITGVPGVGKSTAIE MLBr_01798|M.leprae_Br4923 RAITLVESTRSDHREQAQQLLLALQP-DAGNAHRVGITGVPGVGKSTAIE MAB_2710c|M.abscessus_ATCC_199 RAITLVESTRQDHRSQAQQLLLELSP-EGGNALRVGITGVPGVGKSTTIE * :: :*. : :* : :*:** **.****:: Mflv_2397|M.gilvum_PYR-GCK ALVGSYRSVGMRVAVLAVDPSSPYSGGALLGDRIRMAAHINDPDVLIRSV Mvan_4250|M.vanbaalenii_PYR-1 ALVGAYRLAGKRVAVLAVDPSSPYNGGALLGDRIRMAAHINDPDVLIRSV MSMEG_4869|M.smegmatis_MC2_155 AMVGAYRERGLRVAVLAVDPSSPYSGGALLGDRIRMAAHINDPDVLIRSM TH_0131|M.thermoresistible__bu ALVGAYRERGRRVAVLAVDPSSPYSGGALLGDRIRMAAHINDPDVLIRSV MMAR_4787|M.marinum_M GLVGAYRERGTRVAVLAVDPSSPFSGGALLGDRIRMTAHVNDSEVLIRSV MUL_0356|M.ulcerans_Agy99 GLVGAYRERGTRVAVLAVDPSSPFSGGALLGDRIRMTAHVNDSEVLIRSV MAV_0871|M.avium_104 ALVGAYRRRGCRVAVLAVDPSSPFSGGALLGDRIRMAAHINDSDVLIRSV Mb1533|M.bovis_AF2122/97 ALGMHLIERGHRVAVLAVDPSSTRTGGSILGDKTRMARLAVHPNAYIRPS Rv1496|M.tuberculosis_H37Rv ALGMHLIERGHRVAVLAVDPSSTRTGGSILGDKTRMARLAVHPNAYIRPS MLBr_01798|M.leprae_Br4923 ALGMHLIERGHRVAVLAVDPSSVRTGGSILGDKTRMARLAVHPDAYIRPS MAB_2710c|M.abscessus_ATCC_199 ALGMYLIEQGHRVAVLAVDPSSTRTGGSILGDKTRMGRLSVHPDAYIRPS .: * *********** .**::***: ** ..:. **. Mflv_2397|M.gilvum_PYR-GCK AARGHLGGLAAAVPAAITLLSALGYDLVILETVGVGQSEIEIAAVADPTV Mvan_4250|M.vanbaalenii_PYR-1 ATRGHLGGLAAAVPAAIRLLSALGYDLVILETVGVGQSEIEIAAVADPTV MSMEG_4869|M.smegmatis_MC2_155 AARGHLGGLAAAVPAAIRLLAALSYDLIVLETVGVGQSEIEIAAIADPTV TH_0131|M.thermoresistible__bu ATRGHLGGLAAAVPAAIRLLAALDFDLVVLESVGVGQSEIEIAAIADPTV MMAR_4787|M.marinum_M ASRGHLGGLAASVPAAIRLLGALRYDVVLLETVGVGQSEIEVAAVADPTV MUL_0356|M.ulcerans_Agy99 ASRGHLGGLAASVPAAIRLLGALRYDVVLLKTVGVGQSEIEVVAVADPTV MAV_0871|M.avium_104 ATRGHLGGLAAAVPAAIRLLAAIGYDVVLLETVGVGQSEIEIAAVADPTV Mb1533|M.bovis_AF2122/97 PTSGTLGGVTRATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFV Rv1496|M.tuberculosis_H37Rv PTSGTLGGVTRATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFV MLBr_01798|M.leprae_Br4923 PTSGTLGGVTKATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFV MAB_2710c|M.abscessus_ATCC_199 PTSGTLGGVAKATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFV .: * ***:: :. :: ** * :*::::::*******: :. :.*. * Mflv_2397|M.gilvum_PYR-GCK VILNPGAGDAVQAAKAGLLEVADIVVVNKADRD---GADQTVRDLRAET- Mvan_4250|M.vanbaalenii_PYR-1 VILNPGAGDAVQAAKAGLLEVADVVAVNKADRD---GADQTVRDLRAET- MSMEG_4869|M.smegmatis_MC2_155 VILNPGAGDAVQAAKAGVLEVADLVVVNKADRD---GADQTVRDLRAET- TH_0131|M.thermoresistible__bu VIVNPGAGDAVQAAKAGLLEVADLVVVNKADRD---GADQTARDLRMET- MMAR_4787|M.marinum_M VVLNPGTGDAVQAAKAGLLEVADIVAVNKADRV---GAEQTVRDLRAET- MUL_0356|M.ulcerans_Agy99 VVLNPGTGDAVQAAKAGLLEVADIVAVNKADRV---GAEQTVRDLRAET- MAV_0871|M.avium_104 VILNPGAGDAVQAAKAGVLEVADIVAVNKADRD---GAEQTVRDLRAET- Mb1533|M.bovis_AF2122/97 LLTLARTGDQLQGIKKGVLELADIVVVNKADGEHHKEARLAARELSAAIR Rv1496|M.tuberculosis_H37Rv LLTLARTGDQLQGIKKGVLELADIVVVNKADGEHHKEARLAARELSAAIR MLBr_01798|M.leprae_Br4923 LLALARTGDQLQGIKKGVLELADIVVVNKADGEHLRDARLAARDLSSALR MAB_2710c|M.abscessus_ATCC_199 FLTLARTGDQLQGIKKGVLELADIVVVNKADGEHAIEAKKAARELSGALR .: . :** :*. * *:**:**:*.***** * :.*:* Mflv_2397|M.gilvum_PYR-GCK ---------DVPILKLVAAQGAGLDEVVAAIDAHHRAD--SPERRAAR-- Mvan_4250|M.vanbaalenii_PYR-1 ---------DVPILKLVAAQGDGIAELKEVIEAHHRAD--NPARRAAR-- MSMEG_4869|M.smegmatis_MC2_155 ---------DVPVLKLVAAQGDGLHELIEAIEAHQRAD--TPERRRAR-- TH_0131|M.thermoresistible__bu ---------HLPVLKLVAVQGEGLPELIAAIDGHPRADTDTADRRRAR-- MMAR_4787|M.marinum_M ---------NAPILSLVAVKSEGIGELLALIDAHQRGD--SRDRRLAR-- MUL_0356|M.ulcerans_Agy99 ---------NAPILSLVAVKSEGIGELLALIDAHQRGD--SRDRRLAR-- MAV_0871|M.avium_104 ---------SAPIVSLIAARGEGIEDLMAAIEDHRRTD--SRARRLAR-- Mb1533|M.bovis_AF2122/97 LIYPREALWRPPVLTMSAVEGRGLAELWDTVERHRQVLTGAGEFDARRRD Rv1496|M.tuberculosis_H37Rv LIYPREALWRPPVLTMSAVEGRGLAELWDTVERHRQVLTGAGEFDARRRD MLBr_01798|M.leprae_Br4923 LIYTHEKIWRPKVFTISATEGTGLTQMWEAVECHRQVLTASGEFENRRLA MAB_2710c|M.abscessus_ATCC_199 LIYPHDTLWRPPVLTMSALENNGVSEMWDTVLQHRAVLTEAGEFEAKRRR :..: * .. *: :: : * * Mflv_2397|M.gilvum_PYR-GCK ---------ARSQILSLAQTLLRHHPDLDRLASSVAAGGEDAYTAAERLF Mvan_4250|M.vanbaalenii_PYR-1 ---------ARSQVLSLAQSLLRQHAGLDGLAESVAEGRMDPYTAAARLI MSMEG_4869|M.smegmatis_MC2_155 ---------ARSQILSLAQTLLRNHADLDRLSAAVADGSSDAYTAAERLF TH_0131|M.thermoresistible__bu ---------ARTQILSLAQTQLRNHPDLDRLAEQVADGRRDPYSAAAQLF MMAR_4787|M.marinum_M ---------ARAQILSLAQTRLRGRTDLDRLAEAVVDGLEDPYAAADRLL MUL_0356|M.ulcerans_Agy99 ---------ARAQILSLAQTRLRGRTDLDRLAEAVVDGLEDPYAAADRLL MAV_0871|M.avium_104 ---------ARAQILSLAQTRLRTQPALDRLAEAVVDGTQDPYTAADRLL Mb1533|M.bovis_AF2122/97 QQVDWTWQLVRDAVLDRVWSNPTVRKVRSELERRVRAGELTPALAAQQIL Rv1496|M.tuberculosis_H37Rv QQVDWTWQLVRDAVLDRVWSNPTVRKVRSELERRVRAGELTPALAAQQIL MLBr_01798|M.leprae_Br4923 QQVEWAWQMVRDAVLDRVLSNPAVREIRAELECQVRAGELTPAMAAQQIL MAB_2710c|M.abscessus_ATCC_199 QQVDWMWAMVRDAVLDRVLNAPDVKASRADIEQQVREGTLTPALAAEQLL .* :*. . . : : * * . ** ::: Mflv_2397|M.gilvum_PYR-GCK NVNPDVNPDRPAAGRDEA Mvan_4250|M.vanbaalenii_PYR-1 -VPDSAN----------- MSMEG_4869|M.smegmatis_MC2_155 --AGSVD----------- TH_0131|M.thermoresistible__bu TRPD-------------- MMAR_4787|M.marinum_M APPPP------------- MUL_0356|M.ulcerans_Agy99 APPPP------------- MAV_0871|M.avium_104 SPSRTETD---------- Mb1533|M.bovis_AF2122/97 EIANLTDR---------- Rv1496|M.tuberculosis_H37Rv EIANLTDR---------- MLBr_01798|M.leprae_Br4923 QAASC------------- MAB_2710c|M.abscessus_ATCC_199 NLSS--------------