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SIDDLIAAARNGSQRAAGRLLSLIEGDRRDEVLAGIEDWSQRPARVIGITGPPGAGKSTTITGLVGAYRE RGTRVAVLAVDPSSPFSGGALLGDRIRMTAHVNDSEVLIRSVASRGHLGGLAASVPAAIRLLGALRYDVV LLKTVGVGQSEIEVVAVADPTVVVLNPGTGDAVQAAKAGLLEVADIVAVNKADRVGAEQTVRDLRAETNA PILSLVAVKSEGIGELLALIDAHQRGDSRDRRLARARAQILSLAQTRLRGRTDLDRLAEAVVDGLEDPYA AADRLLAPPPP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0356 | - | - | 100% (292) | transport system kinase |
| M. ulcerans Agy99 | MUL_1507 | - | 3e-39 | 39.76% (254) | arginine/ornithine transport system ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1533 | - | 4e-38 | 38.82% (255) | arginine/ornithine transport system ATPase |
| M. gilvum PYR-GCK | Mflv_2397 | - | 1e-110 | 71.48% (291) | LAO/AO transport system ATPase |
| M. tuberculosis H37Rv | Rv1496 | - | 4e-38 | 38.82% (255) | arginine/ornithine transport system ATPase |
| M. leprae Br4923 | MLBr_01798 | - | 3e-38 | 37.17% (269) | arginine/ornithine transport system ATPase |
| M. abscessus ATCC 19977 | MAB_2710c | - | 2e-37 | 34.18% (316) | putative kinase ArgK |
| M. marinum M | MMAR_4787 | - | 1e-158 | 99.32% (292) | transport system kinase |
| M. avium 104 | MAV_0871 | - | 1e-121 | 78.20% (289) | LAO/AO transport system ATPase |
| M. smegmatis MC2 155 | MSMEG_4869 | - | 1e-110 | 69.79% (288) | LAO/AO transport system ATPase |
| M. thermoresistible (build 8) | TH_0131 | - | 1e-113 | 72.26% (292) | LAO/AO transport system ATPase |
| M. vanbaalenii PYR-1 | Mvan_4250 | - | 1e-111 | 71.63% (289) | LAO/AO transport system ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0356|M.ulcerans_Agy99 -------------------------------MSIDDLIAAARNGSQRAAG
MMAR_4787|M.marinum_M -------------------------------MSIDDLIAAARNGSQRAAG
MAV_0871|M.avium_104 -------------------------------MTIGELIDRARNGSPRAAG
Mflv_2397|M.gilvum_PYR-GCK -------------------------------MTVEELIAAARGGSARATG
Mvan_4250|M.vanbaalenii_PYR-1 MKRSLSSKENIILDNGRVLRRGGARLRTLCEVTIEELIAAARGGSQRATG
MSMEG_4869|M.smegmatis_MC2_155 --------------------------MPHGVVDVPELITVARGGSMRAVG
TH_0131|M.thermoresistible__bu -------------------------------MNIHELVTAARSGSIRAAG
Mb1533|M.bovis_AF2122/97 -----------------------MMAASHDDDTVDGLATAVRGGDRAALP
Rv1496|M.tuberculosis_H37Rv -----------------------MMAASHDDDTVDGLATAVRGGDRAALP
MLBr_01798|M.leprae_Br4923 ------------------------MAG---DSTVDRLVAAVRSGDRVALP
MAB_2710c|M.abscessus_ATCC_199 ------------------------MSAP------DNLAALIRSGDRSGLA
* *.*. .
MUL_0356|M.ulcerans_Agy99 RLLSLIEGDRRDE------VLAGIEDWSQRPARVIGITGPPGAGKSTTIT
MMAR_4787|M.marinum_M RLLSLIEGDRRDE------VLAGIEDWSQRPARVIGITGPPGAGKSTTIT
MAV_0871|M.avium_104 RLLSLVEGEQRDE------VLTAIGPAPRDTGPVIGITGPPGAGKSTTVA
Mflv_2397|M.gilvum_PYR-GCK RLLSYVESPRREA------VLAALG--SVAPARVVGITGPPGAGKSTTVG
Mvan_4250|M.vanbaalenii_PYR-1 RLLSFVESPRRDE------VLDALG--DLLPAQVVGITGPPGAGKSTTVG
MSMEG_4869|M.smegmatis_MC2_155 RLLTLVESDRRGE------VLAALG--PATP-RVIGVTGPPGAGKSTTVG
TH_0131|M.thermoresistible__bu RLLSLVEGPRRDE------VLAALG--ETAPPRVIGITGPPGAGKSTTVG
Mb1533|M.bovis_AF2122/97 RAITLVESTRPDHREQAQQLLLRLLP-DSGNAHRVGITGVPGVGKSTAIE
Rv1496|M.tuberculosis_H37Rv RAITLVESTRPDHREQAQQLLLRLLP-DSGNAHRVGITGVPGVGKSTAIE
MLBr_01798|M.leprae_Br4923 RAITLVESTRSDHREQAQQLLLALQP-DAGNAHRVGITGVPGVGKSTAIE
MAB_2710c|M.abscessus_ATCC_199 RAITLVESTRQDHRSQAQQLLLELSP-EGGNALRVGITGVPGVGKSTTIE
* :: :*. : :* : :*:** **.****::
MUL_0356|M.ulcerans_Agy99 GLVGAYRERGTRVAVLAVDPSSPFSGGALLGDRIRMTAHVNDSEVLIRSV
MMAR_4787|M.marinum_M GLVGAYRERGTRVAVLAVDPSSPFSGGALLGDRIRMTAHVNDSEVLIRSV
MAV_0871|M.avium_104 ALVGAYRRRGCRVAVLAVDPSSPFSGGALLGDRIRMAAHINDSDVLIRSV
Mflv_2397|M.gilvum_PYR-GCK ALVGSYRSVGMRVAVLAVDPSSPYSGGALLGDRIRMAAHINDPDVLIRSV
Mvan_4250|M.vanbaalenii_PYR-1 ALVGAYRLAGKRVAVLAVDPSSPYNGGALLGDRIRMAAHINDPDVLIRSV
MSMEG_4869|M.smegmatis_MC2_155 AMVGAYRERGLRVAVLAVDPSSPYSGGALLGDRIRMAAHINDPDVLIRSM
TH_0131|M.thermoresistible__bu ALVGAYRERGRRVAVLAVDPSSPYSGGALLGDRIRMAAHINDPDVLIRSV
Mb1533|M.bovis_AF2122/97 ALGMHLIERGHRVAVLAVDPSSTRTGGSILGDKTRMARLAVHPNAYIRPS
Rv1496|M.tuberculosis_H37Rv ALGMHLIERGHRVAVLAVDPSSTRTGGSILGDKTRMARLAVHPNAYIRPS
MLBr_01798|M.leprae_Br4923 ALGMHLIERGHRVAVLAVDPSSVRTGGSILGDKTRMARLAVHPDAYIRPS
MAB_2710c|M.abscessus_ATCC_199 ALGMYLIEQGHRVAVLAVDPSSTRTGGSILGDKTRMGRLSVHPDAYIRPS
.: * *********** .**::***: ** ..:. **.
MUL_0356|M.ulcerans_Agy99 ASRGHLGGLAASVPAAIRLLGALRYDVVLLKTVGVGQSEIEVVAVADPTV
MMAR_4787|M.marinum_M ASRGHLGGLAASVPAAIRLLGALRYDVVLLETVGVGQSEIEVAAVADPTV
MAV_0871|M.avium_104 ATRGHLGGLAAAVPAAIRLLAAIGYDVVLLETVGVGQSEIEIAAVADPTV
Mflv_2397|M.gilvum_PYR-GCK AARGHLGGLAAAVPAAITLLSALGYDLVILETVGVGQSEIEIAAVADPTV
Mvan_4250|M.vanbaalenii_PYR-1 ATRGHLGGLAAAVPAAIRLLSALGYDLVILETVGVGQSEIEIAAVADPTV
MSMEG_4869|M.smegmatis_MC2_155 AARGHLGGLAAAVPAAIRLLAALSYDLIVLETVGVGQSEIEIAAIADPTV
TH_0131|M.thermoresistible__bu ATRGHLGGLAAAVPAAIRLLAALDFDLVVLESVGVGQSEIEIAAIADPTV
Mb1533|M.bovis_AF2122/97 PTSGTLGGVTRATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFV
Rv1496|M.tuberculosis_H37Rv PTSGTLGGVTRATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFV
MLBr_01798|M.leprae_Br4923 PTSGTLGGVTKATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFV
MAB_2710c|M.abscessus_ATCC_199 PTSGTLGGVAKATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFV
.: * ***:: :. :: ** * :*::::::*******: :. :.*. *
MUL_0356|M.ulcerans_Agy99 VVLNPGTGDAVQAAKAGLLEVADIVAVNKADRV---GAEQTVRDLRAET-
MMAR_4787|M.marinum_M VVLNPGTGDAVQAAKAGLLEVADIVAVNKADRV---GAEQTVRDLRAET-
MAV_0871|M.avium_104 VILNPGAGDAVQAAKAGVLEVADIVAVNKADRD---GAEQTVRDLRAET-
Mflv_2397|M.gilvum_PYR-GCK VILNPGAGDAVQAAKAGLLEVADIVVVNKADRD---GADQTVRDLRAET-
Mvan_4250|M.vanbaalenii_PYR-1 VILNPGAGDAVQAAKAGLLEVADVVAVNKADRD---GADQTVRDLRAET-
MSMEG_4869|M.smegmatis_MC2_155 VILNPGAGDAVQAAKAGVLEVADLVVVNKADRD---GADQTVRDLRAET-
TH_0131|M.thermoresistible__bu VIVNPGAGDAVQAAKAGLLEVADLVVVNKADRD---GADQTARDLRMET-
Mb1533|M.bovis_AF2122/97 LLTLARTGDQLQGIKKGVLELADIVVVNKADGEHHKEARLAARELSAAIR
Rv1496|M.tuberculosis_H37Rv LLTLARTGDQLQGIKKGVLELADIVVVNKADGEHHKEARLAARELSAAIR
MLBr_01798|M.leprae_Br4923 LLALARTGDQLQGIKKGVLELADIVVVNKADGEHLRDARLAARDLSSALR
MAB_2710c|M.abscessus_ATCC_199 FLTLARTGDQLQGIKKGVLELADIVVVNKADGEHAIEAKKAARELSGALR
.: . :** :*. * *:**:**:*.***** * :.*:*
MUL_0356|M.ulcerans_Agy99 ---------NAPILSLVAVKSEGIGELLALIDAHQRGD--SRDRRLAR--
MMAR_4787|M.marinum_M ---------NAPILSLVAVKSEGIGELLALIDAHQRGD--SRDRRLAR--
MAV_0871|M.avium_104 ---------SAPIVSLIAARGEGIEDLMAAIEDHRRTD--SRARRLAR--
Mflv_2397|M.gilvum_PYR-GCK ---------DVPILKLVAAQGAGLDEVVAAIDAHHRAD--SPERRAAR--
Mvan_4250|M.vanbaalenii_PYR-1 ---------DVPILKLVAAQGDGIAELKEVIEAHHRAD--NPARRAAR--
MSMEG_4869|M.smegmatis_MC2_155 ---------DVPVLKLVAAQGDGLHELIEAIEAHQRAD--TPERRRAR--
TH_0131|M.thermoresistible__bu ---------HLPVLKLVAVQGEGLPELIAAIDGHPRADTDTADRRRAR--
Mb1533|M.bovis_AF2122/97 LIYPREALWRPPVLTMSAVEGRGLAELWDTVERHRQVLTGAGEFDARRRD
Rv1496|M.tuberculosis_H37Rv LIYPREALWRPPVLTMSAVEGRGLAELWDTVERHRQVLTGAGEFDARRRD
MLBr_01798|M.leprae_Br4923 LIYTHEKIWRPKVFTISATEGTGLTQMWEAVECHRQVLTASGEFENRRLA
MAB_2710c|M.abscessus_ATCC_199 LIYPHDTLWRPPVLTMSALENNGVSEMWDTVLQHRAVLTEAGEFEAKRRR
:..: * .. *: :: : * *
MUL_0356|M.ulcerans_Agy99 ---------ARAQILSLAQTRLRGRTDLDRLAEAVVDGLEDPYAAADRLL
MMAR_4787|M.marinum_M ---------ARAQILSLAQTRLRGRTDLDRLAEAVVDGLEDPYAAADRLL
MAV_0871|M.avium_104 ---------ARAQILSLAQTRLRTQPALDRLAEAVVDGTQDPYTAADRLL
Mflv_2397|M.gilvum_PYR-GCK ---------ARSQILSLAQTLLRHHPDLDRLASSVAAGGEDAYTAAERLF
Mvan_4250|M.vanbaalenii_PYR-1 ---------ARSQVLSLAQSLLRQHAGLDGLAESVAEGRMDPYTAAARLI
MSMEG_4869|M.smegmatis_MC2_155 ---------ARSQILSLAQTLLRNHADLDRLSAAVADGSSDAYTAAERLF
TH_0131|M.thermoresistible__bu ---------ARTQILSLAQTQLRNHPDLDRLAEQVADGRRDPYSAAAQLF
Mb1533|M.bovis_AF2122/97 QQVDWTWQLVRDAVLDRVWSNPTVRKVRSELERRVRAGELTPALAAQQIL
Rv1496|M.tuberculosis_H37Rv QQVDWTWQLVRDAVLDRVWSNPTVRKVRSELERRVRAGELTPALAAQQIL
MLBr_01798|M.leprae_Br4923 QQVEWAWQMVRDAVLDRVLSNPAVREIRAELECQVRAGELTPAMAAQQIL
MAB_2710c|M.abscessus_ATCC_199 QQVDWMWAMVRDAVLDRVLNAPDVKASRADIEQQVREGTLTPALAAEQLL
.* :*. . . : : * * . ** :::
MUL_0356|M.ulcerans_Agy99 APPPP-------------
MMAR_4787|M.marinum_M APPPP-------------
MAV_0871|M.avium_104 SPSRTETD----------
Mflv_2397|M.gilvum_PYR-GCK NVNPDVNPDRPAAGRDEA
Mvan_4250|M.vanbaalenii_PYR-1 -VPDSAN-----------
MSMEG_4869|M.smegmatis_MC2_155 --AGSVD-----------
TH_0131|M.thermoresistible__bu TRPD--------------
Mb1533|M.bovis_AF2122/97 EIANLTDR----------
Rv1496|M.tuberculosis_H37Rv EIANLTDR----------
MLBr_01798|M.leprae_Br4923 QAASC-------------
MAB_2710c|M.abscessus_ATCC_199 NLSS--------------