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NPVLPGSICQIGYVVADLDDAISRWLQMGVGPWFVIRGMTQRVRFRGEPCEVTLSLALSNSGDLQIELIQ QHGDTHSVFTEFLAATGGGFHQLAYWARDFDAAVADLEDAGWPEVWSGGEAEGVRFAYYEPPAGATVIEI MELTDASAGMATFVRQAVRAWDGSDPVRELGGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4776 | - | - | 100% (174) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. smegmatis MC2 155 | MSMEG_3658 | - | 5e-10 | 31.87% (160) | hypothetical protein MSMEG_3658 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2521 | - | 2e-65 | 67.06% (170) | hypothetical protein Mflv_2521 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2388 | - | 4e-12 | 34.97% (143) | hypothetical protein MAB_2388 |
| M. marinum M | MMAR_2693 | - | 1e-08 | 31.21% (141) | hypothetical protein MMAR_2693 |
| M. avium 104 | MAV_2898 | - | 4e-10 | 28.93% (159) | hypothetical protein MAV_2898 |
| M. thermoresistible (build 8) | TH_1535 | - | 1e-06 | 28.57% (168) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3063 | - | 1e-08 | 26.75% (157) | flavoprotein |
| M. vanbaalenii PYR-1 | Mvan_4137 | - | 1e-59 | 63.74% (171) | hypothetical protein Mvan_4137 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2693|M.marinum_M MNLSVRSP--------TQIAWVTPDLDATEAALTGLLGARKWVR-IPDVH
MUL_3063|M.ulcerans_Agy99 MNLSVRSP--------TQIAWVTPDLDATEAAFTGLLGARKWVR-IPDVH
MAV_2898|M.avium_104 ----MQSP--------TQIAWVTGDLDATETALTGLLGVRKWVR-IPDVH
MAB_2388|M.abscessus_ATCC_1997 MTTSAMPPDVSGFGRVTQIAWVTDDLDATEAMLSAVFGVKKWTR-IPDVH
Mflv_2521|M.gilvum_PYR-GCK MT--LPGPIR-------QIGYVVTDLDSALEEWMALG-VGPWFV-IRGIP
Mvan_4137|M.vanbaalenii_PYR-1 MT--LPGPIR-------QIGYVVTDLDRALDSWVALG-VGPWYV-IREMP
MSMEG_4776|M.smegmatis_MC2_155 MNPVLPGSIC-------QIGYVVADLDDAISRWLQMG-VGPWFV-IRGMT
TH_1535|M.thermoresistible__bu MTTDQVDARP------LLPTALVTAVDHVGIAVADLDAAIKWYHDNLGMI
. :. :* . : . * :
MMAR_2693|M.marinum_M FAPDSCSYRGKPADFVASISLSYLGDMQLELISPVRGE-NIYSDFLRDCG
MUL_3063|M.ulcerans_Agy99 FAPDSCSYRGKPADFVASISLSYLGDMQLELISPVRGE-NIYSDFPRDCG
MAV_2898|M.avium_104 FAADACSYRGKPADFVASISLSYLGDMQLELIQPVRGE-NIYSDFLSDGG
MAB_2388|M.abscessus_ATCC_1997 FGPETCTYRGAPADFTATIALSYLDDMQLELILPVSGT-SIYTEFLERNS
Mflv_2521|M.gilvum_PYR-GCK QR---VTYRGHPCEITLSLALANSGDLQVELIHQDDDTPSIFTEFLTAHG
Mvan_4137|M.vanbaalenii_PYR-1 QR---VTYRGEPCAVTLSLALANSGDLQVELIHQHDDTPSIFTEFLDSGR
MSMEG_4776|M.smegmatis_MC2_155 QR---VRFRGEPCEVTLSLALSNSGDLQIELIQQHGDTHSVFTEFLAATG
TH_1535|M.thermoresistible__bu VLHEEVNEEQGVREAMLSVRGAPVGSTQIQLMAPLGPD-STIAKFLDKRG
. :: : .. *::*: . :.*
MMAR_2693|M.marinum_M PGLHHICLEVEGPEQLEIALAEAADHGASVVQRGSMPGG---IQFAYVAA
MUL_3063|M.ulcerans_Agy99 PGLHHICLEVEGPEQLEIALAEAADHGASVVQRGSMPGG---IQFAYVAA
MAV_2898|M.avium_104 PGLHHICVEADSPEQLAEALARAGERGAPVVQQGVMPGG---IHFAYVSA
MAB_2388|M.abscessus_ATCC_1997 AGLHHVCVE---PPDLDVALDHATSQGMEVVQDGVMPGG---MRFAYLSA
Mflv_2521|M.gilvum_PYR-GCK PGFHQFAYWS---ADFDRAMRAVAEAGWPVVWSGGEDLG---TRFAYVEP
Mvan_4137|M.vanbaalenii_PYR-1 PGFHQLAYWT---DDFEGTMGSVAEAGWPVVWNGASGPGGAVTRFAYVEP
MSMEG_4776|M.smegmatis_MC2_155 GGFHQLAYWA---RDFDAAVADLEDAGWPEVWSGGEAEG---VRFAYYEP
TH_1535|M.thermoresistible__bu PGLQQLAYRVR---DIEAISEGLREQGIRLLYDEPRRGTAN-SRINFIHP
*:::.. :: . * : :: : .
MMAR_2693|M.marinum_M PQAGVPFVEIAYFSPEIKTFYDYIKREQR---------------------
MUL_3063|M.ulcerans_Agy99 PQAGVPFVEIAYFSPEIKAFYDYIKRAALNTEIPATVSSDTVTSWTDDVD
MAV_2898|M.avium_104 PQAGVPFVEFAYIAPEMRAFYDYIKQQQR---------------------
MAB_2388|M.abscessus_ATCC_1997 PAAALPYMELVFVPPEIRAFYDYIKNEQA---------------------
Mflv_2521|M.gilvum_PYR-GCK PGGPAAIIEIMELTDTTQGMATFVRDAAANWDGADAIRELSG--------
Mvan_4137|M.vanbaalenii_PYR-1 PDSPAAVIEIMELSPATEGMATFLREAAAAWDGRDPVRELSV--------
MSMEG_4776|M.smegmatis_MC2_155 PAG-ATVIEIMELTDASAGMATFVRQAVRAWDGSDPVRELGGA-------
TH_1535|M.thermoresistible__bu KDAGGVLIELVEPAPNGSDH------------------------------
. :*: .
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 VVVIGFGIAGGCAAVAAAAAGARVLVLERAAAAGGTTSLAGGHFYLGGGT
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 AVQQATGHSDTPDEMYKYLAAVSRQPDHAKIRAYCDGSVEHFNWLEDLGF
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 QFERSYFPGKAVIQPNTEGLMFTGNEKVWPFFEKAVPAPRGHKVPVPGDT
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 GGASMVIDLLLKRGASLGVQIRYETGATELIVAGSGTAARVAGVMWKRFT
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 ETGAIKAKSVIIAAGGFVMNPEMVAKYTPKLAEKPFVLGNTYDDGLGIRM
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 GVSAGGATEHMDQIFVTAPPYPPSILLTGVIVNKLGRRFVAEDSYHSRTA
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 GFIMDQPDSAAYLIVDEAHLQHPKMPLVPLIDGWESVAEMEAALGIPDCN
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 LVAALDRYNTYAARGEDPDFHKQPEFLAPQDKGPWGAFDMSLGKAMYAGF
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 TLGGLATSVDGEVLRSDGSVVAGLYAAGACASNIAQDGKGYASGTQLGEG
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MMAR_2693|M.marinum_M ---------------------
MUL_3063|M.ulcerans_Agy99 SFFGRRAGAHAAAHACARVAP
MAV_2898|M.avium_104 ---------------------
MAB_2388|M.abscessus_ATCC_1997 ---------------------
Mflv_2521|M.gilvum_PYR-GCK ---------------------
Mvan_4137|M.vanbaalenii_PYR-1 ---------------------
MSMEG_4776|M.smegmatis_MC2_155 ---------------------
TH_1535|M.thermoresistible__bu ---------------------