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PNQTPVQIAWVTRDLDRTEQALTTLLGARRWIRMPAVRFGPDTCTHRGRPADFTADVALSYAGDIQLEVI APVDGESVYTEFLDRCGPGLHHVCLEMPDTEAFDERLRAAARDGTPAVCHGELAGGMRFAYLSAADAGVP YQEIAYFPPEIRAFFDYVKQEQQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3658 | - | - | 100% (164) | hypothetical protein MSMEG_3658 |
| M. smegmatis MC2 155 | MSMEG_4776 | - | 4e-10 | 31.87% (160) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. smegmatis MC2 155 | MSMEG_4921 | mce | 2e-06 | 31.11% (90) | methylmalonyl-CoA epimerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1357c | - | 5e-05 | 38.64% (44) | hypothetical protein Mb1357c |
| M. gilvum PYR-GCK | Mflv_3412 | - | 3e-61 | 63.58% (162) | hypothetical protein Mflv_3412 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_01157 | - | 6e-05 | 34.04% (47) | hypothetical protein MLBr_01157 |
| M. abscessus ATCC 19977 | MAB_2388 | - | 7e-50 | 58.33% (156) | hypothetical protein MAB_2388 |
| M. marinum M | MMAR_2693 | - | 9e-55 | 57.14% (161) | hypothetical protein MMAR_2693 |
| M. avium 104 | MAV_2898 | - | 2e-52 | 55.90% (161) | hypothetical protein MAV_2898 |
| M. thermoresistible (build 8) | TH_1535 | - | 5e-05 | 39.13% (46) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3063 | - | 8e-53 | 56.33% (158) | flavoprotein |
| M. vanbaalenii PYR-1 | Mvan_3166 | - | 1e-62 | 70.37% (162) | hypothetical protein Mvan_3166 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3412|M.gilvum_PYR-GCK --MHDQTP--------VQIAWVTQDLTATETALTALMGAKKWVR-MPGVH
Mvan_3166|M.vanbaalenii_PYR-1 --MLDQTP--------VQIAWVTRDLDATETALTSLLGARRWVR-MPGVH
MSMEG_3658|M.smegmatis_MC2_155 --MPNQTP--------VQIAWVTRDLDRTEQALTTLLGARRWIR-MPAVR
MMAR_2693|M.marinum_M MNLSVRSP--------TQIAWVTPDLDATEAALTGLLGARKWVR-IPDVH
MUL_3063|M.ulcerans_Agy99 MNLSVRSP--------TQIAWVTPDLDATEAAFTGLLGARKWVR-IPDVH
MAV_2898|M.avium_104 ----MQSP--------TQIAWVTGDLDATETALTGLLGVRKWVR-IPDVH
MAB_2388|M.abscessus_ATCC_1997 MTTSAMPPDVSGFGRVTQIAWVTDDLDATEAMLSAVFGVKKWTR-IPDVH
Mb1357c|M.bovis_AF2122/97 MMTTDQVH-----ARHMLATSLVTGLDHVGIAVADLDVAIEWYHDHLGMI
MLBr_01157|M.leprae_Br4923 MMTTDQIN-----TCQLLATTLVITIDHVGIAVADLNAAISWYHDHLGMI
TH_1535|M.thermoresistible__bu -MTTDQVD-----ARPLLPTALVTAVDHVGIAVADLDAAIKWYHDNLGMI
: :. : . .: : . * : :
Mflv_3412|M.gilvum_PYR-GCK FGPETCTYRGEPADFVADISLSYAGDTQLELIAPVSGTSIYTEFLGRSGP
Mvan_3166|M.vanbaalenii_PYR-1 FGPDTCTYRGGPADFVADISLSYAGDTQLELIAPVSGDSIYREFLDRCGP
MSMEG_3658|M.smegmatis_MC2_155 FGPDTCTHRGRPADFTADVALSYAGDIQLEVIAPVDGESVYTEFLDRCGP
MMAR_2693|M.marinum_M FAPDSCSYRGKPADFVASISLSYLGDMQLELISPVRGENIYSDFLRDCGP
MUL_3063|M.ulcerans_Agy99 FAPDSCSYRGKPADFVASISLSYLGDMQLELISPVRGENIYSDFPRDCGP
MAV_2898|M.avium_104 FAADACSYRGKPADFVASISLSYLGDMQLELIQPVRGENIYSDFLSDGGP
MAB_2388|M.abscessus_ATCC_1997 FGPETCTYRGAPADFTATIALSYLDDMQLELILPVSGTSIYTEFLERNSA
Mb1357c|M.bovis_AF2122/97 LVHEEINDDQGIREALLAVPGS---AAQIQLMAPLDESSVIAKFLDKRGP
MLBr_01157|M.leprae_Br4923 LVHEEVNDDQGIREAMLSAHGAPIGTTQIQLMAPINESSPIAKFLDKHGP
TH_1535|M.thermoresistible__bu VLHEEVNEEQGVREAMLSVRGAPVGSTQIQLMAPLGPDSTIAKFLDKRGP
. : . : : *:::: *: . .* ..
Mflv_3412|M.gilvum_PYR-GCK GLHHVCTAYPDPDSFEAAVARAGQDGIPVVMEGTMPGGMRFAYVGAEHAG
Mvan_3166|M.vanbaalenii_PYR-1 GLHHVCVALA-ADEFDAAVAQAD-----IVMAGTMAGGMRFAYASAADAG
MSMEG_3658|M.smegmatis_MC2_155 GLHHVCLEMPDTEAFDERLRAAARDGTPAVCHGELAGGMRFAYLSAADAG
MMAR_2693|M.marinum_M GLHHICLEVEGPEQLEIALAEAADHGASVVQRGSMPGGIQFAYVAAPQAG
MUL_3063|M.ulcerans_Agy99 GLHHICLEVEGPEQLEIALAEAADHGASVVQRGSMPGGIQFAYVAAPQAG
MAV_2898|M.avium_104 GLHHICVEADSPEQLAEALARAGERGAPVVQQGVMPGGIHFAYVSAPQAG
MAB_2388|M.abscessus_ATCC_1997 GLHHVCVEPP---DLDVALDHATSQGMEVVQDGVMPGGMRFAYLSAPAAA
Mb1357c|M.bovis_AF2122/97 GIQQLACRVSDLDAMCRRLRSQGVRLVYETARRGTAN-SRINFIHPKDAG
MLBr_01157|M.leprae_Br4923 GIQQLACRVSDLDRLTKRLRAQGVRLVYDTPRQGTSN-ARINFIHPKDAG
TH_1535|M.thermoresistible__bu GLQQLAYRVRDIEAISEGLREQGIRLLYDEPRRGTAN-SRINFIHPKDAG
*::::. : : .. :: : . *.
Mflv_3412|M.gilvum_PYR-GCK VPYLEFAYIPDEIHALFDHIKQEQK-------------------------
Mvan_3166|M.vanbaalenii_PYR-1 VPFIEFAYIPPEIRAFFDHIKQEQK-------------------------
MSMEG_3658|M.smegmatis_MC2_155 VPYQEIAYFPPEIRAFFDYVKQEQQ-------------------------
MMAR_2693|M.marinum_M VPFVEIAYFSPEIKTFYDYIKREQR-------------------------
MUL_3063|M.ulcerans_Agy99 VPFVEIAYFSPEIKAFYDYIKRAALNTEIPATVSSDTVTSWTDDVDVVVI
MAV_2898|M.avium_104 VPFVEFAYIAPEMRAFYDYIKQQQR-------------------------
MAB_2388|M.abscessus_ATCC_1997 LPYMELVFVPPEIRAFYDYIKNEQA-------------------------
Mb1357c|M.bovis_AF2122/97 GVLIELVEPAP---------------------------------------
MLBr_01157|M.leprae_Br4923 GVLIELVEPAS---------------------------------------
TH_1535|M.thermoresistible__bu GVLIELVEPAPNGSDH----------------------------------
*:. .
Mflv_3412|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3166|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3658|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 GFGIAGGCAAVAAAAAGARVLVLERAAAAGGTTSLAGGHFYLGGGTAVQQ
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mflv_3412|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3166|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3658|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 ATGHSDTPDEMYKYLAAVSRQPDHAKIRAYCDGSVEHFNWLEDLGFQFER
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mflv_3412|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3166|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3658|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 SYFPGKAVIQPNTEGLMFTGNEKVWPFFEKAVPAPRGHKVPVPGDTGGAS
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mflv_3412|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3166|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3658|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 MVIDLLLKRGASLGVQIRYETGATELIVAGSGTAARVAGVMWKRFTETGA
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mflv_3412|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3166|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3658|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 IKAKSVIIAAGGFVMNPEMVAKYTPKLAEKPFVLGNTYDDGLGIRMGVSA
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mflv_3412|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3166|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3658|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 GGATEHMDQIFVTAPPYPPSILLTGVIVNKLGRRFVAEDSYHSRTAGFIM
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mflv_3412|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3166|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3658|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 DQPDSAAYLIVDEAHLQHPKMPLVPLIDGWESVAEMEAALGIPDCNLVAA
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mflv_3412|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3166|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3658|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 LDRYNTYAARGEDPDFHKQPEFLAPQDKGPWGAFDMSLGKAMYAGFTLGG
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mflv_3412|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3166|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3658|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 LATSVDGEVLRSDGSVVAGLYAAGACASNIAQDGKGYASGTQLGEGSFFG
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mflv_3412|M.gilvum_PYR-GCK -----------------
Mvan_3166|M.vanbaalenii_PYR-1 -----------------
MSMEG_3658|M.smegmatis_MC2_155 -----------------
MMAR_2693|M.marinum_M -----------------
MUL_3063|M.ulcerans_Agy99 RRAGAHAAAHACARVAP
MAV_2898|M.avium_104 -----------------
MAB_2388|M.abscessus_ATCC_1997 -----------------
Mb1357c|M.bovis_AF2122/97 -----------------
MLBr_01157|M.leprae_Br4923 -----------------
TH_1535|M.thermoresistible__bu -----------------