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TLPGPIRQIGYVVTDLDRALDSWVALGVGPWYVIREMPQRVTYRGEPCAVTLSLALANSGDLQVELIHQH DDTPSIFTEFLDSGRPGFHQLAYWTDDFEGTMGSVAEAGWPVVWNGASGPGGAVTRFAYVEPPDSPAAVI EIMELSPATEGMATFLREAAAAWDGRDPVRELSV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4137 | - | - | 100% (175) | hypothetical protein Mvan_4137 |
| M. vanbaalenii PYR-1 | Mvan_3166 | - | 8e-09 | 32.88% (146) | hypothetical protein Mvan_3166 |
| M. vanbaalenii PYR-1 | Mvan_4306 | - | 7e-08 | 28.78% (139) | glyoxalase/bleomycin resistance protein/dioxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1357c | - | 3e-06 | 28.78% (139) | hypothetical protein Mb1357c |
| M. gilvum PYR-GCK | Mflv_2521 | - | 2e-74 | 74.71% (174) | hypothetical protein Mflv_2521 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2388 | - | 7e-14 | 31.48% (162) | hypothetical protein MAB_2388 |
| M. marinum M | MMAR_2693 | - | 9e-11 | 30.57% (157) | hypothetical protein MMAR_2693 |
| M. avium 104 | MAV_2898 | - | 8e-13 | 31.65% (158) | hypothetical protein MAV_2898 |
| M. smegmatis MC2 155 | MSMEG_4776 | - | 1e-59 | 63.74% (171) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. thermoresistible (build 8) | TH_1535 | - | 7e-07 | 27.46% (142) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3063 | - | 1e-11 | 30.63% (160) | flavoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4137|M.vanbaalenii_PYR-1 -MT--LPGPIR-------QIGYVVTDLDRALDSWVALG-VGPWYV-IREM
Mflv_2521|M.gilvum_PYR-GCK -MT--LPGPIR-------QIGYVVTDLDSALEEWMALG-VGPWFV-IRGI
MSMEG_4776|M.smegmatis_MC2_155 -MNPVLPGSIC-------QIGYVVADLDDAISRWLQMG-VGPWFV-IRGM
MMAR_2693|M.marinum_M -MNLSVRSP--------TQIAWVTPDLDATEAALTGLLGARKWVR-IPDV
MUL_3063|M.ulcerans_Agy99 -MNLSVRSP--------TQIAWVTPDLDATEAAFTGLLGARKWVR-IPDV
MAV_2898|M.avium_104 -----MQSP--------TQIAWVTGDLDATETALTGLLGVRKWVR-IPDV
MAB_2388|M.abscessus_ATCC_1997 -MTTSAMPPDVSGFGRVTQIAWVTDDLDATEAMLSAVFGVKKWTR-IPDV
Mb1357c|M.bovis_AF2122/97 MMTTDQVHARH------MLATSLVTGLDHVGIAVADLDVAIEWYHDHLGM
TH_1535|M.thermoresistible__bu -MTTDQVDARP------LLPTALVTAVDHVGIAVADLDAAIKWYHDNLGM
. :. :* . : . * :
Mvan_4137|M.vanbaalenii_PYR-1 PQR---VTYRGEPCAVTLSLALANSGDLQVELIHQHDDTPSIFTEFLDSG
Mflv_2521|M.gilvum_PYR-GCK PQR---VTYRGHPCEITLSLALANSGDLQVELIHQDDDTPSIFTEFLTAH
MSMEG_4776|M.smegmatis_MC2_155 TQR---VRFRGEPCEVTLSLALSNSGDLQIELIQQHGDTHSVFTEFLAAT
MMAR_2693|M.marinum_M HFAPDSCSYRGKPADFVASISLSYLGDMQLELISPVRGE-NIYSDFLRDC
MUL_3063|M.ulcerans_Agy99 HFAPDSCSYRGKPADFVASISLSYLGDMQLELISPVRGE-NIYSDFPRDC
MAV_2898|M.avium_104 HFAADACSYRGKPADFVASISLSYLGDMQLELIQPVRGE-NIYSDFLSDG
MAB_2388|M.abscessus_ATCC_1997 HFGPETCTYRGAPADFTATIALSYLDDMQLELILPVSGT-SIYTEFLERN
Mb1357c|M.bovis_AF2122/97 ILVHEEINDDQGIREALLAVPGS---AAQIQLMAPLDES-SVIAKFLDKR
TH_1535|M.thermoresistible__bu IVLHEEVNEEQGVREAMLSVRGAPVGSTQIQLMAPLGPD-STIAKFLDKR
:: : *::*: . :.*
Mvan_4137|M.vanbaalenii_PYR-1 RPGFHQLAYWT---DDFEGTMGSVAEAGWPVVWNGASGPGGAVTRFAYVE
Mflv_2521|M.gilvum_PYR-GCK GPGFHQFAYWS---ADFDRAMRAVAEAGWPVVWSGGEDLG---TRFAYVE
MSMEG_4776|M.smegmatis_MC2_155 GGGFHQLAYWA---RDFDAAVADLEDAGWPEVWSGGEAEG---VRFAYYE
MMAR_2693|M.marinum_M GPGLHHICLEVEGPEQLEIALAEAADHGASVVQRGSMPGG---IQFAYVA
MUL_3063|M.ulcerans_Agy99 GPGLHHICLEVEGPEQLEIALAEAADHGASVVQRGSMPGG---IQFAYVA
MAV_2898|M.avium_104 GPGLHHICVEADSPEQLAEALARAGERGAPVVQQGVMPGG---IHFAYVS
MAB_2388|M.abscessus_ATCC_1997 SAGLHHVCVE---PPDLDVALDHATSQGMEVVQDGVMPGG---MRFAYLS
Mb1357c|M.bovis_AF2122/97 GPGIQQLACRVS---DLDAMCRRLRSQGVRLVYETARRGTAN-SRINFIH
TH_1535|M.thermoresistible__bu GPGLQQLAYRVR---DIEAISEGLREQGIRLLYDEPRRGTAN-SRINFIH
*:::.. :: . * : :: :
Mvan_4137|M.vanbaalenii_PYR-1 PPDSPAAVIEIMELSPATEGMATFLREAAAAWDGRDPVRELSV-------
Mflv_2521|M.gilvum_PYR-GCK PPGGPAAIIEIMELTDTTQGMATFVRDAAANWDGADAIRELSG-------
MSMEG_4776|M.smegmatis_MC2_155 PPAG-ATVIEIMELTDASAGMATFVRQAVRAWDGSDPVRELGGA------
MMAR_2693|M.marinum_M APQAGVPFVEIAYFSPEIKTFYDYIKREQR--------------------
MUL_3063|M.ulcerans_Agy99 APQAGVPFVEIAYFSPEIKAFYDYIKRAALNTEIPATVSSDTVTSWTDDV
MAV_2898|M.avium_104 APQAGVPFVEFAYIAPEMRAFYDYIKQQQR--------------------
MAB_2388|M.abscessus_ATCC_1997 APAAALPYMELVFVPPEIRAFYDYIKNEQA--------------------
Mb1357c|M.bovis_AF2122/97 PKDAGGVLIELVEPAP----------------------------------
TH_1535|M.thermoresistible__bu PKDAGGVLIELVEPAPNGSDH-----------------------------
. . :*: .
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 DVVVIGFGIAGGCAAVAAAAAGARVLVLERAAAAGGTTSLAGGHFYLGGG
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 TAVQQATGHSDTPDEMYKYLAAVSRQPDHAKIRAYCDGSVEHFNWLEDLG
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 FQFERSYFPGKAVIQPNTEGLMFTGNEKVWPFFEKAVPAPRGHKVPVPGD
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 TGGASMVIDLLLKRGASLGVQIRYETGATELIVAGSGTAARVAGVMWKRF
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 TETGAIKAKSVIIAAGGFVMNPEMVAKYTPKLAEKPFVLGNTYDDGLGIR
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 MGVSAGGATEHMDQIFVTAPPYPPSILLTGVIVNKLGRRFVAEDSYHSRT
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 AGFIMDQPDSAAYLIVDEAHLQHPKMPLVPLIDGWESVAEMEAALGIPDC
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 NLVAALDRYNTYAARGEDPDFHKQPEFLAPQDKGPWGAFDMSLGKAMYAG
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2521|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4776|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2693|M.marinum_M --------------------------------------------------
MUL_3063|M.ulcerans_Agy99 FTLGGLATSVDGEVLRSDGSVVAGLYAAGACASNIAQDGKGYASGTQLGE
MAV_2898|M.avium_104 --------------------------------------------------
MAB_2388|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
Mvan_4137|M.vanbaalenii_PYR-1 ----------------------
Mflv_2521|M.gilvum_PYR-GCK ----------------------
MSMEG_4776|M.smegmatis_MC2_155 ----------------------
MMAR_2693|M.marinum_M ----------------------
MUL_3063|M.ulcerans_Agy99 GSFFGRRAGAHAAAHACARVAP
MAV_2898|M.avium_104 ----------------------
MAB_2388|M.abscessus_ATCC_1997 ----------------------
Mb1357c|M.bovis_AF2122/97 ----------------------
TH_1535|M.thermoresistible__bu ----------------------