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M. smegmatis MC2 155 MSMEG_4687 (-)

annotation: cytosine deaminase
coordinates: 4772916 - 4773356
length: 146

TPEQMLDVAVEEARKGLSEGGIPIGAALFSADGELLGSGHNRRVQDGDPSIHAETDAFRAAGRQRGYRKT
IMVTTLSPCWYCSGLVRQFNIGALVIGEARTFSGGHEWLADNGVSVTLLDDERCVTMMQDFITANPDLWA
EDIGE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4687--100% (146)cytosine deaminase
M. smegmatis MC2 155MSMEG_6327-7e-1134.78% (115) cytidine and deoxycytidylate deaminase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3778c-5e-0834.41% (93) cytidine/deoxycytidylate deaminase
M. gilvum PYR-GCKMflv_2579-1e-6981.51% (146) CMP/dCMP deaminase, zinc-binding
M. tuberculosis H37RvRv3752c-5e-0834.41% (93) cytidine/deoxycytidylate deaminase
M. leprae Br4923MLBr_02474-2e-0934.21% (114) putative cytidine/deoxycytidylate deaminase
M. abscessus ATCC 19977MAB_0268-4e-1133.93% (112) cytidine/deoxycytidylate deaminase family protein
M. marinum MMMAR_5295-1e-0937.63% (93) cytidine/deoxycytidylate deaminase
M. avium 104MAV_0324-2e-0836.56% (93) cytidine and deoxycytidylate deaminase family protein
M. thermoresistible (build 8)TH_1653-9e-1235.65% (115) POSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE
M. ulcerans Agy99MUL_4370-5e-1037.63% (93) cytidine/deoxycytidylate deaminase
M. vanbaalenii PYR-1Mvan_4055-5e-7486.90% (145) CMP/dCMP deaminase, zinc-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mb3778c|M.bovis_AF2122/97           -----------------MTTDEDLIRAALAVAATAGPRD-VPVGAVVVGA
Rv3752c|M.tuberculosis_H37Rv        -----------------MTTDEDLIRAALAVAATAGPRD-VPVGAVVVGA
MLBr_02474|M.leprae_Br4923          ----MPSAAGRRHQTRSVTTDEDLIRAALTVATTAGSRD-VPIGAVVLGA
MAV_0324|M.avium_104                -----------------MISDEDLIRSALAVAATAGPRD-VPIGAVVVGA
MMAR_5295|M.marinum_M               -----------------MIADEDLVRAALAAAATAGPRD-VPIGAVVISA
MUL_4370|M.ulcerans_Agy99           -----------------MIADEDLVRAALAAAATAGPRD-VPIGAVMISA
TH_1653|M.thermoresistible__bu      --------------MIGSVTDEDMIRAALTAAREAGPRD-VPIGAVVFGP
MAB_0268|M.abscessus_ATCC_1997      ---------------MTFPDDEALIRAALVAAREAGSQD-VPIGAVIYAA
Mflv_2579|M.gilvum_PYR-GCK          ------------------MTASQMLDVAVEEARKGLAEGGIPIGAALFAA
Mvan_4055|M.vanbaalenii_PYR-1       MIRILGGVSLQDHRREGVATPQEMLEVAVEEARKGLAEGGIPIGAALFST
MSMEG_4687|M.smegmatis_MC2_155      ------------------MTPEQMLDVAVEEARKGLSEGGIPIGAALFSA
                                                         . ::  *:  *  . ... :*:**.: ..

Mb3778c|M.bovis_AF2122/97           DGTELARAVNAREALGDPTAHAEILAMRLAAGVLGDGWRLEGTTLAVTVE
Rv3752c|M.tuberculosis_H37Rv        DGTELARAVNAREALGDPTAHAEILAMRLAAGVLGDGWRLEGTTLAVTVE
MLBr_02474|M.leprae_Br4923          DGNELARAVNAREAIGDPTAHAEILAMRAAAGTLGNGWRLEGTTLAVTVE
MAV_0324|M.avium_104                DGTELARAVNAREALGDPTAHAEILALRAAAAALGDGWRLEGATLAVTVE
MMAR_5295|M.marinum_M               DGTELARAVNAREELGDPTAHAEILALRAAARVLGDGWRLEGATLAVTVE
MUL_4370|M.ulcerans_Agy99           DGTELARAVNAREELGDPTAHAEILALRAAARVLGDGWRLEGATLAVTVE
TH_1653|M.thermoresistible__bu      DGGELARAANAREQLGDPTAHAEVLALRAAARRLGDGWRLEGATLAVTVE
MAB_0268|M.abscessus_ATCC_1997      DGTELARAANARERLGDPTAHAEVLALRAAAAKHGDGWRLEGATLAVTVE
Mflv_2579|M.gilvum_PYR-GCK          DGTLLGSGHNRRVQLDDPSLHAETDAFRNAGRQRG----YRSTTMVTTLS
Mvan_4055|M.vanbaalenii_PYR-1       DGALLGSGHNRRVQLGDPSVHAETDAFRNAGRQRG----YRSTIMVTTLS
MSMEG_4687|M.smegmatis_MC2_155      DGELLGSGHNRRVQDGDPSIHAETDAFRAAGRQRG----YRKTIMVTTLS
                                    **  *. . * *   .**: ***  *:* *.   *     . : :..*:.

Mb3778c|M.bovis_AF2122/97           PCTMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGG
Rv3752c|M.tuberculosis_H37Rv        PCTMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGG
MLBr_02474|M.leprae_Br4923          PCTMCAGALVLARIERLVFGAWQPKTGAVGSLWDVVRDHRLNHRPAVRGG
MAV_0324|M.avium_104                PCTMCAGALVLARIARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGG
MMAR_5295|M.marinum_M               PCTMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPQVRGG
MUL_4370|M.ulcerans_Agy99           PCTMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPQVRGG
TH_1653|M.thermoresistible__bu      PCTMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGG
MAB_0268|M.abscessus_ATCC_1997      PCTMCAGALVLARVGRVVFGAWEPKTGAVGSLWDVVRDRRQAHRPEVRGG
Mflv_2579|M.gilvum_PYR-GCK          PCWYCSGLVRQFNIGTVVIGESRTFTG--GHDWLAEHGVKVTVVDDERCV
Mvan_4055|M.vanbaalenii_PYR-1       PCWYCSGLVRQFNIGAVVIGESRTFTG--GHDWLADNGVDVTIVDDERCV
MSMEG_4687|M.smegmatis_MC2_155      PCWYCSGLVRQFNIGALVIGEARTFSG--GHEWLADNGVSVTLLDDERCV
                                    **  *:* :   .:  :*:*  .. :*  *  * . ..         *  

Mb3778c|M.bovis_AF2122/97           VLARECAAPLEAFFARQRLG-------
Rv3752c|M.tuberculosis_H37Rv        VLARECAAPLEAFFARQRLG-------
MLBr_02474|M.leprae_Br4923          VLAQECTAPLEAFFAHQRLSKGPPVR-
MAV_0324|M.avium_104                VLERECAALLEGFFARQRLG-------
MMAR_5295|M.marinum_M               VLAQECAAPLEEFFGRQRLG-------
MUL_4370|M.ulcerans_Agy99           VLAQECAAPLEEFFGRQRLG-------
TH_1653|M.thermoresistible__bu      VLAAECAAPLEEFFARQRDPDSPRGLG
MAB_0268|M.abscessus_ATCC_1997      VLEHECAALLERFFAAKR---------
Mflv_2579|M.gilvum_PYR-GCK          TLMRDFIAGNPELWAEDIGE-------
Mvan_4055|M.vanbaalenii_PYR-1       TMMRDFIAANPDLWAEDIGE-------
MSMEG_4687|M.smegmatis_MC2_155      TMMQDFITANPDLWAEDIGE-------
                                    .:  :  :    ::. .