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MGRVTARRRAHHVTLDRSEARPETLVVEEPLEIRVNGTPITVTMRTPGSDIELAQGFLLTEGVIRRRDDL LAVRYCRGATEDGVNTYNVLDVTLAPDVPAPDVDVTRNFYTTSSCGVCGKASLEAVRLISKHCPGDDPAT ITAETLASMPTQLRRAQKVFNSTGGLHGAALFDADGNMLVVREDIGRHNAVDKVIGWAVEQERVPLSGTV LLVSGRASFELTQKAVMAGIPVLAAVSAPSSLAVDLASQSGLTLVAFLRGESMNVYTRPDRVMN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4669 | fdhD | - | 100% (274) | formate dehydrogenase accessory protein |
| M. smegmatis MC2 155 | MSMEG_0165 | fdhD | e-102 | 66.54% (272) | formate dehydrogenase accessory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2923c | fdhD | 1e-110 | 72.36% (275) | formate dehydrogenase accessory protein |
| M. gilvum PYR-GCK | Mflv_2593 | - | 1e-129 | 82.97% (276) | formate dehydrogenase accessory protein |
| M. tuberculosis H37Rv | Rv2899c | fdhD | 1e-110 | 72.36% (275) | formate dehydrogenase accessory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1592c | - | 1e-110 | 73.53% (272) | formate dehydrogenase accessory protein |
| M. marinum M | MMAR_1811 | fdhD | 1e-117 | 76.92% (273) | formate dehydrogenase family accessory protein, FdhD |
| M. avium 104 | MAV_3753 | fdhD | 1e-112 | 73.70% (270) | formate dehydrogenase accessory protein |
| M. thermoresistible (build 8) | TH_1165 | fdhD | 1e-116 | 75.55% (274) | POSSIBLE FDHD PROTEIN HOMOLOG |
| M. ulcerans Agy99 | MUL_2059 | fdhD | 1e-115 | 75.82% (273) | formate dehydrogenase accessory protein |
| M. vanbaalenii PYR-1 | Mvan_4033 | - | 1e-125 | 78.75% (287) | formate dehydrogenase accessory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2593|M.gilvum_PYR-GCK MGRVTARRRVRRVTADDTVARPETLVVEEPLEIRVNGTPITVTMRTPGSD
Mvan_4033|M.vanbaalenii_PYR-1 MGRVTARRRVHHVTTGDAVARPDTLVVEEPLEIRVNGAPITVTMRTPGSD
MSMEG_4669|M.smegmatis_MC2_155 MGRVTARRRAHHVTLDRSEARPETLVVEEPLEIRVNGTPITVTMRTPGSD
MAB_1592c|M.abscessus_ATCC_199 MGRVTDRRKVRRIEGVGRGDRSETLVVEEPLEIRVNGQAVAVTMRTPGSD
TH_1165|M.thermoresistible__bu MGRVTTRRRVHHLRAGTLTTRPETLVVEEPLEIRLNGAPLTVTMRTPGAD
Mb2923c|M.bovis_AF2122/97 MGYATAHRRVRHLSADQVITRPETLAVEEPLEIRVNGTPVTVTMRTPGSD
Rv2899c|M.tuberculosis_H37Rv MGYATAHRRVRHLSADQVITRPETLAVEEPLEIRVNGTPVTVTMRTPGSD
MMAR_1811|M.marinum_M MGHVTARRRVKHLAAGDAITRPETLAVEEPLEIRVNGVPISVTMRTPGSD
MUL_2059|M.ulcerans_Agy99 MGHVTARRRVKHLAAGDAITRPETLAVEEPLEIRVNGVPISVTMRTPGSD
MAV_3753|M.avium_104 -MQVTSRRRVTHLTAGQATTRPETLVVEEPLEIRVGGAAVTVTMRTPGSD
.* :*:. :: *.:**.********:.* .::*******:*
Mflv_2593|M.gilvum_PYR-GCK VELAQGFLLTEGIVRRREDILSVRYCRGATE------DSS---GYSQNTY
Mvan_4033|M.vanbaalenii_PYR-1 VELAQGFLLTEGIISSREDIVSVRYCRGAPVPVPESLRSSPPEEQAANTY
MSMEG_4669|M.smegmatis_MC2_155 IELAQGFLLTEGVIRRRDDLLAVRYCRGATE-------------DGVNTY
MAB_1592c|M.abscessus_ATCC_199 VELTQGFLLTEGVIASRDDLLTVRYCQGEGP-------------DGLNTY
TH_1165|M.thermoresistible__bu FELARGFLVGEGVITRRDDVATVRYCPGGTT-------------DGRNTY
Mb2923c|M.bovis_AF2122/97 FELVQGFLLAEGVVAHREDVLTVSYCGRRVEG----------NATGASTY
Rv2899c|M.tuberculosis_H37Rv FELVQGFLLAEGVVAHREDVLTVSYCGRRVEG----------NATGASTY
MMAR_1811|M.marinum_M FELARGFLLTEGVIAHRDDVLTVRYCGGR-------------GADGVNTY
MUL_2059|M.ulcerans_Agy99 FEPARGFLLTEGVIAHRDDVLTVRYCGGR-------------GADGANTY
MAV_3753|M.avium_104 FELAQGFLLTEGIIGAREDVHSIRYCAGR-------------GEDGANSY
.* .:***: **:: *:*: :: ** . .:*
Mflv_2593|M.gilvum_PYR-GCK NVLDVTLAPDVPAPDVD-PTRNFYTTSSCGVCGKASLDAVRLSSKHAPGD
Mvan_4033|M.vanbaalenii_PYR-1 NVLDVTLAHGVPTPDVD-PTRNFYTTSSCGVCGKASLDAVRLISKHAPGD
MSMEG_4669|M.smegmatis_MC2_155 NVLDVTLAPDVPAPDVD-VTRNFYTTSSCGVCGKASLEAVRLISKHCPGD
MAB_1592c|M.abscessus_ATCC_199 NVLDVALAPGVAAPDPT-VTRNFYTTSSCGVCGKGSLDAVRTISRFSPGD
TH_1165|M.thermoresistible__bu NVLDVTLTPGVAPPAPELVTRNFYTTSSCGVCGKASLDAVELVSRHSPGD
Mb2923c|M.bovis_AF2122/97 NVLDVALAPGVKPPDVD-VTRTFYTTSSCGVCGKASLQAVSQVSRFAPGG
Rv2899c|M.tuberculosis_H37Rv NVLDVALAPGVKPPDVD-VTRTFYTTSSCGVCGKASLQAVSQVSRFAPGG
MMAR_1811|M.marinum_M NVLDITLAPGVSPPGLD-VTRNFYTTSSCGVCGKASLDAVRLISRFSPGD
MUL_2059|M.ulcerans_Agy99 NVLDITLAPGVSPSGLD-VTRNFYTTSSCGVCGKASLDAVRLISRFSPGD
MAV_3753|M.avium_104 NVLDVTLAAGLGRPELD-ITRNFYTTSSCGVCGKASLEAVRSVSRFSPAA
****::*: .: . **.************.**:** *:..*.
Mflv_2593|M.gilvum_PYR-GCK DPSVVTAEVLSALPDRLRAEQKVFAATGGLHGAALFSTDGDTLVVREDIG
Mvan_4033|M.vanbaalenii_PYR-1 DPATVTAETLSALPDKLRDAQKVFAATGGLHGAALFGTDGTELVVREDIG
MSMEG_4669|M.smegmatis_MC2_155 DPATITAETLASMPTQLRRAQKVFNSTGGLHGAALFDADGNMLVVREDIG
MAB_1592c|M.abscessus_ATCC_199 DPSTIGSNTLAGLPDKLRSRQKVFATTGGLHAAALFTLDGTVLAVREDIG
TH_1165|M.thermoresistible__bu DPATVAAVTVAELPDRLRAAQKVFASTGGLHAAALFSTAGECLVVREDVG
Mb2923c|M.bovis_AF2122/97 DPATVAADTLKAMPDQLRRAQKVFARTGGLHAAALFGVDGAMLAVREDIG
Rv2899c|M.tuberculosis_H37Rv DPATVAADTLKAMPDQLRRAQKVFARTGGLHAAALFGVDGAMLAVREDIG
MMAR_1811|M.marinum_M DPATITAGALEAMPGQLRSGQKVFASTGGLHAAALFSADGTMHVIREDIG
MUL_2059|M.ulcerans_Agy99 DPATITAGALEAMPGQLRSGQKVFASTGGLHAAALFSADGTMHVIREDIG
MAV_3753|M.avium_104 DPATVAAATLQAMPHQLRSAQKVFDSTGGLHAAALFRADGTMLVVREDVG
**:.: : .: :* :** **** *****.**** * .:***:*
Mflv_2593|M.gilvum_PYR-GCK RHNAVDKVVGWALEQHRIPLGGTVLLVSGRASFELTQKAVMAGIPVLAAV
Mvan_4033|M.vanbaalenii_PYR-1 RHNAVDKVVGWALENRRIPLGDTVLLVSGRASFELTQKAVMAGIPVLAAV
MSMEG_4669|M.smegmatis_MC2_155 RHNAVDKVIGWAVEQERVPLSGTVLLVSGRASFELTQKAVMAGIPVLAAV
MAB_1592c|M.abscessus_ATCC_199 RHNAVDKVIGWALENDKVPLTGTVLLVSGRASFELAQKATMAGIPILAAV
TH_1165|M.thermoresistible__bu RHNAVDKVIGWALEQDRLPLAGTVLLVSGRASFELTQKAVMAGVPILAAV
Mb2923c|M.bovis_AF2122/97 RHNAVDKVIGWAFERDRIPLGASVLLVSGRASFELTQKALMAGIPVLAAV
Rv2899c|M.tuberculosis_H37Rv RHNAVDKVIGWAFERDRIPLGASVLLVSGRASFELTQKALMAGIPVLAAV
MMAR_1811|M.marinum_M RHNAADKVIGWAIEHDRVPLAGSVLLVSGRASFELTQKALMAGIPVLAAV
MUL_2059|M.ulcerans_Agy99 RHNAADKVIGWAIEHDRVPLAGSVLLVSGRASFELTQKALMAGIPVLAAV
MAV_3753|M.avium_104 RHNAVDKVIGWALEQQRLPLRATVLLVSGRASFELAQKAVMAGIPVLAAV
****.***:***.*. ::** :************:*** ***:*:****
Mflv_2593|M.gilvum_PYR-GCK SAPSSLAVDLAGQSGLTLVAFLRGESMNVYSRPDRVAH
Mvan_4033|M.vanbaalenii_PYR-1 SAPSSLAVDLASQSGLTLVAFLRGDSMNVYTRPDRVKN
MSMEG_4669|M.smegmatis_MC2_155 SAPSSLAVDLASQSGLTLVAFLRGESMNVYTRPDRVMN
MAB_1592c|M.abscessus_ATCC_199 SAPSSLAVDLAAQSGMTLVAFLREDSMNIYTRADRVS-
TH_1165|M.thermoresistible__bu SAPSSLAVDLAQRSGLTLIAFLRGASMNIYTRRDRVTV
Mb2923c|M.bovis_AF2122/97 SAPSSLAVSLADASGITLVAFLRGDSMNVYTRADRIT-
Rv2899c|M.tuberculosis_H37Rv SAPSSLAVSLADASGITLVAFLRGDSMNVYTRADRIT-
MMAR_1811|M.marinum_M SAPSSLAVSLAEESGMTLVAFLREDSMNVYTRPDRIV-
MUL_2059|M.ulcerans_Agy99 SAPSSLAVSLAEESGMTLVAFLREDSMNVYTRPDRIV-
MAV_3753|M.avium_104 SAPSSLAVSLAEESGVTLVAFLREDSMNIYTRADRIG-
********.** **:**:**** ***:*:* **: