For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_3753 (fdhD)

annotation: formate dehydrogenase accessory protein
coordinates: 3879593 - 3880411
length: 272

QVTSRRRVTHLTAGQATTRPETLVVEEPLEIRVGGAAVTVTMRTPGSDFELAQGFLLTEGIIGAREDVHS
IRYCAGRGEDGANSYNVLDVTLAAGLGRPELDITRNFYTTSSCGVCGKASLEAVRSVSRFSPAADPATVA
AATLQAMPHQLRSAQKVFDSTGGLHAAALFRADGTMLVVREDVGRHNAVDKVIGWALEQQRLPLRATVLL
VSGRASFELAQKAVMAGIPVLAAVSAPSSLAVSLAEESGVTLVAFLREDSMNIYTRADRIG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_3753fdhD-100% (272)formate dehydrogenase accessory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2923cfdhD1e-11074.54% (271) formate dehydrogenase accessory protein
M. gilvum PYR-GCKMflv_2593-1e-10570.07% (274) formate dehydrogenase accessory protein
M. tuberculosis H37RvRv2899cfdhD1e-11074.54% (271) formate dehydrogenase accessory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1592c-1e-10871.11% (270) formate dehydrogenase accessory protein
M. marinum MMMAR_1811fdhD1e-11877.70% (269) formate dehydrogenase family accessory protein, FdhD
M. smegmatis MC2 155MSMEG_4669fdhD1e-11273.70% (270) formate dehydrogenase accessory protein
M. thermoresistible (build 8)TH_1165fdhD1e-10873.43% (271) POSSIBLE FDHD PROTEIN HOMOLOG
M. ulcerans Agy99MUL_2059fdhD1e-11777.32% (269) formate dehydrogenase accessory protein
M. vanbaalenii PYR-1Mvan_4033-1e-11071.38% (283) formate dehydrogenase accessory protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2593|M.gilvum_PYR-GCK          MGRVTARRRVRRVTADDTVARPETLVVEEPLEIRVNGTPITVTMRTPGSD
Mvan_4033|M.vanbaalenii_PYR-1       MGRVTARRRVHHVTTGDAVARPDTLVVEEPLEIRVNGAPITVTMRTPGSD
MSMEG_4669|M.smegmatis_MC2_155      MGRVTARRRAHHVTLDRSEARPETLVVEEPLEIRVNGTPITVTMRTPGSD
MAB_1592c|M.abscessus_ATCC_199      MGRVTDRRKVRRIEGVGRGDRSETLVVEEPLEIRVNGQAVAVTMRTPGSD
TH_1165|M.thermoresistible__bu      MGRVTTRRRVHHLRAGTLTTRPETLVVEEPLEIRLNGAPLTVTMRTPGAD
Mb2923c|M.bovis_AF2122/97           MGYATAHRRVRHLSADQVITRPETLAVEEPLEIRVNGTPVTVTMRTPGSD
Rv2899c|M.tuberculosis_H37Rv        MGYATAHRRVRHLSADQVITRPETLAVEEPLEIRVNGTPVTVTMRTPGSD
MMAR_1811|M.marinum_M               MGHVTARRRVKHLAAGDAITRPETLAVEEPLEIRVNGVPISVTMRTPGSD
MUL_2059|M.ulcerans_Agy99           MGHVTARRRVKHLAAGDAITRPETLAVEEPLEIRVNGVPISVTMRTPGSD
MAV_3753|M.avium_104                -MQVTSRRRVTHLTAGQATTRPETLVVEEPLEIRVGGAAVTVTMRTPGSD
                                       .* :*:. ::       *.:**.********:.* .::*******:*

Mflv_2593|M.gilvum_PYR-GCK          VELAQGFLLTEGIVRRREDILSVRYCRGATE------DSS---GYSQNTY
Mvan_4033|M.vanbaalenii_PYR-1       VELAQGFLLTEGIISSREDIVSVRYCRGAPVPVPESLRSSPPEEQAANTY
MSMEG_4669|M.smegmatis_MC2_155      IELAQGFLLTEGVIRRRDDLLAVRYCRGATE-------------DGVNTY
MAB_1592c|M.abscessus_ATCC_199      VELTQGFLLTEGVIASRDDLLTVRYCQGEGP-------------DGLNTY
TH_1165|M.thermoresistible__bu      FELARGFLVGEGVITRRDDVATVRYCPGGTT-------------DGRNTY
Mb2923c|M.bovis_AF2122/97           FELVQGFLLAEGVVAHREDVLTVSYCGRRVEG----------NATGASTY
Rv2899c|M.tuberculosis_H37Rv        FELVQGFLLAEGVVAHREDVLTVSYCGRRVEG----------NATGASTY
MMAR_1811|M.marinum_M               FELARGFLLTEGVIAHRDDVLTVRYCGGR-------------GADGVNTY
MUL_2059|M.ulcerans_Agy99           FEPARGFLLTEGVIAHRDDVLTVRYCGGR-------------GADGANTY
MAV_3753|M.avium_104                FELAQGFLLTEGIIGAREDVHSIRYCAGR-------------GEDGANSY
                                    .* .:***: **::  *:*: :: **                   . .:*

Mflv_2593|M.gilvum_PYR-GCK          NVLDVTLAPDVPAPDVD-PTRNFYTTSSCGVCGKASLDAVRLSSKHAPGD
Mvan_4033|M.vanbaalenii_PYR-1       NVLDVTLAHGVPTPDVD-PTRNFYTTSSCGVCGKASLDAVRLISKHAPGD
MSMEG_4669|M.smegmatis_MC2_155      NVLDVTLAPDVPAPDVD-VTRNFYTTSSCGVCGKASLEAVRLISKHCPGD
MAB_1592c|M.abscessus_ATCC_199      NVLDVALAPGVAAPDPT-VTRNFYTTSSCGVCGKGSLDAVRTISRFSPGD
TH_1165|M.thermoresistible__bu      NVLDVTLTPGVAPPAPELVTRNFYTTSSCGVCGKASLDAVELVSRHSPGD
Mb2923c|M.bovis_AF2122/97           NVLDVALAPGVKPPDVD-VTRTFYTTSSCGVCGKASLQAVSQVSRFAPGG
Rv2899c|M.tuberculosis_H37Rv        NVLDVALAPGVKPPDVD-VTRTFYTTSSCGVCGKASLQAVSQVSRFAPGG
MMAR_1811|M.marinum_M               NVLDITLAPGVSPPGLD-VTRNFYTTSSCGVCGKASLDAVRLISRFSPGD
MUL_2059|M.ulcerans_Agy99           NVLDITLAPGVSPSGLD-VTRNFYTTSSCGVCGKASLDAVRLISRFSPGD
MAV_3753|M.avium_104                NVLDVTLAAGLGRPELD-ITRNFYTTSSCGVCGKASLEAVRSVSRFSPAA
                                    ****::*: .:  .     **.************.**:**   *:..*. 

Mflv_2593|M.gilvum_PYR-GCK          DPSVVTAEVLSALPDRLRAEQKVFAATGGLHGAALFSTDGDTLVVREDIG
Mvan_4033|M.vanbaalenii_PYR-1       DPATVTAETLSALPDKLRDAQKVFAATGGLHGAALFGTDGTELVVREDIG
MSMEG_4669|M.smegmatis_MC2_155      DPATITAETLASMPTQLRRAQKVFNSTGGLHGAALFDADGNMLVVREDIG
MAB_1592c|M.abscessus_ATCC_199      DPSTIGSNTLAGLPDKLRSRQKVFATTGGLHAAALFTLDGTVLAVREDIG
TH_1165|M.thermoresistible__bu      DPATVAAVTVAELPDRLRAAQKVFASTGGLHAAALFSTAGECLVVREDVG
Mb2923c|M.bovis_AF2122/97           DPATVAADTLKAMPDQLRRAQKVFARTGGLHAAALFGVDGAMLAVREDIG
Rv2899c|M.tuberculosis_H37Rv        DPATVAADTLKAMPDQLRRAQKVFARTGGLHAAALFGVDGAMLAVREDIG
MMAR_1811|M.marinum_M               DPATITAGALEAMPGQLRSGQKVFASTGGLHAAALFSADGTMHVIREDIG
MUL_2059|M.ulcerans_Agy99           DPATITAGALEAMPGQLRSGQKVFASTGGLHAAALFSADGTMHVIREDIG
MAV_3753|M.avium_104                DPATVAAATLQAMPHQLRSAQKVFDSTGGLHAAALFRADGTMLVVREDVG
                                    **:.: : .:  :* :**  ****  *****.****   *   .:***:*

Mflv_2593|M.gilvum_PYR-GCK          RHNAVDKVVGWALEQHRIPLGGTVLLVSGRASFELTQKAVMAGIPVLAAV
Mvan_4033|M.vanbaalenii_PYR-1       RHNAVDKVVGWALENRRIPLGDTVLLVSGRASFELTQKAVMAGIPVLAAV
MSMEG_4669|M.smegmatis_MC2_155      RHNAVDKVIGWAVEQERVPLSGTVLLVSGRASFELTQKAVMAGIPVLAAV
MAB_1592c|M.abscessus_ATCC_199      RHNAVDKVIGWALENDKVPLTGTVLLVSGRASFELAQKATMAGIPILAAV
TH_1165|M.thermoresistible__bu      RHNAVDKVIGWALEQDRLPLAGTVLLVSGRASFELTQKAVMAGVPILAAV
Mb2923c|M.bovis_AF2122/97           RHNAVDKVIGWAFERDRIPLGASVLLVSGRASFELTQKALMAGIPVLAAV
Rv2899c|M.tuberculosis_H37Rv        RHNAVDKVIGWAFERDRIPLGASVLLVSGRASFELTQKALMAGIPVLAAV
MMAR_1811|M.marinum_M               RHNAADKVIGWAIEHDRVPLAGSVLLVSGRASFELTQKALMAGIPVLAAV
MUL_2059|M.ulcerans_Agy99           RHNAADKVIGWAIEHDRVPLAGSVLLVSGRASFELTQKALMAGIPVLAAV
MAV_3753|M.avium_104                RHNAVDKVIGWALEQQRLPLRATVLLVSGRASFELAQKAVMAGIPVLAAV
                                    ****.***:***.*. ::**  :************:*** ***:*:****

Mflv_2593|M.gilvum_PYR-GCK          SAPSSLAVDLAGQSGLTLVAFLRGESMNVYSRPDRVAH
Mvan_4033|M.vanbaalenii_PYR-1       SAPSSLAVDLASQSGLTLVAFLRGDSMNVYTRPDRVKN
MSMEG_4669|M.smegmatis_MC2_155      SAPSSLAVDLASQSGLTLVAFLRGESMNVYTRPDRVMN
MAB_1592c|M.abscessus_ATCC_199      SAPSSLAVDLAAQSGMTLVAFLREDSMNIYTRADRVS-
TH_1165|M.thermoresistible__bu      SAPSSLAVDLAQRSGLTLIAFLRGASMNIYTRRDRVTV
Mb2923c|M.bovis_AF2122/97           SAPSSLAVSLADASGITLVAFLRGDSMNVYTRADRIT-
Rv2899c|M.tuberculosis_H37Rv        SAPSSLAVSLADASGITLVAFLRGDSMNVYTRADRIT-
MMAR_1811|M.marinum_M               SAPSSLAVSLAEESGMTLVAFLREDSMNVYTRPDRIV-
MUL_2059|M.ulcerans_Agy99           SAPSSLAVSLAEESGMTLVAFLREDSMNVYTRPDRIV-
MAV_3753|M.avium_104                SAPSSLAVSLAEESGVTLVAFLREDSMNIYTRADRIG-
                                    ********.**  **:**:****  ***:*:* **: