For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_0165 (fdhD)

annotation: formate dehydrogenase accessory protein
coordinates: 189944 - 190786
length: 280

MGRVTNRYRVVRLAEGGAAERPDTLAAEEPLEIRVAGRPLTVTMRTPGNDFDLARGFLVSEGVVARAGDI
AGIRYCAGATRDGSNTYNVLDVVLAEGVTAPDASLERNFYTTSSCGVCGKASLEAVRTVSSWTVGDDPVE
LSAATIVTMPDQLRAAQRVFDRTGGLHAAALFDVDGELLCVREDVGRHNAVDKVIGWALDGDRLPLRGTV
LMVSGRASFELVQKAVMAGIPAMAAVSAPSSLAVDLAREMGLTLVGFLRGATMNIYAGAERISDDRFATV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0165fdhD-100% (280)formate dehydrogenase accessory protein
M. smegmatis MC2 155MSMEG_4669fdhDe-10266.54% (272) formate dehydrogenase accessory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2923cfdhD2e-9362.68% (276) formate dehydrogenase accessory protein
M. gilvum PYR-GCKMflv_2593-2e-9864.98% (277) formate dehydrogenase accessory protein
M. tuberculosis H37RvRv2899cfdhD2e-9362.68% (276) formate dehydrogenase accessory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1592c-2e-9863.74% (273) formate dehydrogenase accessory protein
M. marinum MMMAR_1811fdhD1e-9863.97% (272) formate dehydrogenase family accessory protein, FdhD
M. avium 104MAV_3753fdhD1e-10167.41% (270) formate dehydrogenase accessory protein
M. thermoresistible (build 8)TH_1165fdhD1e-10368.98% (274) POSSIBLE FDHD PROTEIN HOMOLOG
M. ulcerans Agy99MUL_2059fdhD2e-9763.24% (272) formate dehydrogenase accessory protein
M. vanbaalenii PYR-1Mvan_4033-1e-9661.67% (287) formate dehydrogenase accessory protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2593|M.gilvum_PYR-GCK          MGRVTARRRVRRVTADDTVARPETLVVEEPLEIRVNGTPITVTMRTPGSD
Mvan_4033|M.vanbaalenii_PYR-1       MGRVTARRRVHHVTTGDAVARPDTLVVEEPLEIRVNGAPITVTMRTPGSD
MAB_1592c|M.abscessus_ATCC_199      MGRVTDRRKVRRIEGVGRGDRSETLVVEEPLEIRVNGQAVAVTMRTPGSD
Mb2923c|M.bovis_AF2122/97           MGYATAHRRVRHLSADQVITRPETLAVEEPLEIRVNGTPVTVTMRTPGSD
Rv2899c|M.tuberculosis_H37Rv        MGYATAHRRVRHLSADQVITRPETLAVEEPLEIRVNGTPVTVTMRTPGSD
MMAR_1811|M.marinum_M               MGHVTARRRVKHLAAGDAITRPETLAVEEPLEIRVNGVPISVTMRTPGSD
MUL_2059|M.ulcerans_Agy99           MGHVTARRRVKHLAAGDAITRPETLAVEEPLEIRVNGVPISVTMRTPGSD
MAV_3753|M.avium_104                -MQVTSRRRVTHLTAGQATTRPETLVVEEPLEIRVGGAAVTVTMRTPGSD
TH_1165|M.thermoresistible__bu      MGRVTTRRRVHHLRAGTLTTRPETLVVEEPLEIRLNGAPLTVTMRTPGAD
MSMEG_0165|M.smegmatis_MC2_155      MGRVTNRYRVVRLAEGGAAERPDTLAAEEPLEIRVAGRPLTVTMRTPGND
                                       .* : :* ::       *.:**..*******: * .::******* *

Mflv_2593|M.gilvum_PYR-GCK          VELAQGFLLTEGIVRRREDILSVRYCRGATE------DSS---GYSQNTY
Mvan_4033|M.vanbaalenii_PYR-1       VELAQGFLLTEGIISSREDIVSVRYCRGAPVPVPESLRSSPPEEQAANTY
MAB_1592c|M.abscessus_ATCC_199      VELTQGFLLTEGVIASRDDLLTVRYCQGEGP-------------DGLNTY
Mb2923c|M.bovis_AF2122/97           FELVQGFLLAEGVVAHREDVLTVSYCGRRVEG----------NATGASTY
Rv2899c|M.tuberculosis_H37Rv        FELVQGFLLAEGVVAHREDVLTVSYCGRRVEG----------NATGASTY
MMAR_1811|M.marinum_M               FELARGFLLTEGVIAHRDDVLTVRYCGGR-------------GADGVNTY
MUL_2059|M.ulcerans_Agy99           FEPARGFLLTEGVIAHRDDVLTVRYCGGR-------------GADGANTY
MAV_3753|M.avium_104                FELAQGFLLTEGIIGAREDVHSIRYCAGR-------------GEDGANSY
TH_1165|M.thermoresistible__bu      FELARGFLVGEGVITRRDDVATVRYCPGG-------------TTDGRNTY
MSMEG_0165|M.smegmatis_MC2_155      FDLARGFLVSEGVVARAGDIAGIRYCAGATR-------------DGSNTY
                                    .: .:***: **::    *:  : **                   . .:*

Mflv_2593|M.gilvum_PYR-GCK          NVLDVTLAPDVPAPDVD-PTRNFYTTSSCGVCGKASLDAVRLSSKHAPGD
Mvan_4033|M.vanbaalenii_PYR-1       NVLDVTLAHGVPTPDVD-PTRNFYTTSSCGVCGKASLDAVRLISKHAPGD
MAB_1592c|M.abscessus_ATCC_199      NVLDVALAPGVAAPDPT-VTRNFYTTSSCGVCGKGSLDAVRTISRFSPGD
Mb2923c|M.bovis_AF2122/97           NVLDVALAPGVKPPDVD-VTRTFYTTSSCGVCGKASLQAVSQVSRFAPGG
Rv2899c|M.tuberculosis_H37Rv        NVLDVALAPGVKPPDVD-VTRTFYTTSSCGVCGKASLQAVSQVSRFAPGG
MMAR_1811|M.marinum_M               NVLDITLAPGVSPPGLD-VTRNFYTTSSCGVCGKASLDAVRLISRFSPGD
MUL_2059|M.ulcerans_Agy99           NVLDITLAPGVSPSGLD-VTRNFYTTSSCGVCGKASLDAVRLISRFSPGD
MAV_3753|M.avium_104                NVLDVTLAAGLGRPELD-ITRNFYTTSSCGVCGKASLEAVRSVSRFSPAA
TH_1165|M.thermoresistible__bu      NVLDVTLTPGVAPPAPELVTRNFYTTSSCGVCGKASLDAVELVSRHSPGD
MSMEG_0165|M.smegmatis_MC2_155      NVLDVVLAEGVTAPDAS-LERNFYTTSSCGVCGKASLEAVRTVSSWTVGD
                                    ****:.*: .:  .      *.************.**:**   *  : . 

Mflv_2593|M.gilvum_PYR-GCK          DPSVVTAEVLSALPDRLRAEQKVFAATGGLHGAALFSTDGDTLVVREDIG
Mvan_4033|M.vanbaalenii_PYR-1       DPATVTAETLSALPDKLRDAQKVFAATGGLHGAALFGTDGTELVVREDIG
MAB_1592c|M.abscessus_ATCC_199      DPSTIGSNTLAGLPDKLRSRQKVFATTGGLHAAALFTLDGTVLAVREDIG
Mb2923c|M.bovis_AF2122/97           DPATVAADTLKAMPDQLRRAQKVFARTGGLHAAALFGVDGAMLAVREDIG
Rv2899c|M.tuberculosis_H37Rv        DPATVAADTLKAMPDQLRRAQKVFARTGGLHAAALFGVDGAMLAVREDIG
MMAR_1811|M.marinum_M               DPATITAGALEAMPGQLRSGQKVFASTGGLHAAALFSADGTMHVIREDIG
MUL_2059|M.ulcerans_Agy99           DPATITAGALEAMPGQLRSGQKVFASTGGLHAAALFSADGTMHVIREDIG
MAV_3753|M.avium_104                DPATVAAATLQAMPHQLRSAQKVFDSTGGLHAAALFRADGTMLVVREDVG
TH_1165|M.thermoresistible__bu      DPATVAAVTVAELPDRLRAAQKVFASTGGLHAAALFSTAGECLVVREDVG
MSMEG_0165|M.smegmatis_MC2_155      DPVELSAATIVTMPDQLRAAQRVFDRTGGLHAAALFDVDGELLCVREDVG
                                    **  : : .:  :* :**  *:**  *****.****   *    :***:*

Mflv_2593|M.gilvum_PYR-GCK          RHNAVDKVVGWALEQHRIPLGGTVLLVSGRASFELTQKAVMAGIPVLAAV
Mvan_4033|M.vanbaalenii_PYR-1       RHNAVDKVVGWALENRRIPLGDTVLLVSGRASFELTQKAVMAGIPVLAAV
MAB_1592c|M.abscessus_ATCC_199      RHNAVDKVIGWALENDKVPLTGTVLLVSGRASFELAQKATMAGIPILAAV
Mb2923c|M.bovis_AF2122/97           RHNAVDKVIGWAFERDRIPLGASVLLVSGRASFELTQKALMAGIPVLAAV
Rv2899c|M.tuberculosis_H37Rv        RHNAVDKVIGWAFERDRIPLGASVLLVSGRASFELTQKALMAGIPVLAAV
MMAR_1811|M.marinum_M               RHNAADKVIGWAIEHDRVPLAGSVLLVSGRASFELTQKALMAGIPVLAAV
MUL_2059|M.ulcerans_Agy99           RHNAADKVIGWAIEHDRVPLAGSVLLVSGRASFELTQKALMAGIPVLAAV
MAV_3753|M.avium_104                RHNAVDKVIGWALEQQRLPLRATVLLVSGRASFELAQKAVMAGIPVLAAV
TH_1165|M.thermoresistible__bu      RHNAVDKVIGWALEQDRLPLAGTVLLVSGRASFELTQKAVMAGVPILAAV
MSMEG_0165|M.smegmatis_MC2_155      RHNAVDKVIGWALDGDRLPLRGTVLMVSGRASFELVQKAVMAGIPAMAAV
                                    ****.***:***::  ::**  :**:*********.*** ***:* :***

Mflv_2593|M.gilvum_PYR-GCK          SAPSSLAVDLAGQSGLTLVAFLRGESMNVYSRPDRVAH------
Mvan_4033|M.vanbaalenii_PYR-1       SAPSSLAVDLASQSGLTLVAFLRGDSMNVYTRPDRVKN------
MAB_1592c|M.abscessus_ATCC_199      SAPSSLAVDLAAQSGMTLVAFLREDSMNIYTRADRVS-------
Mb2923c|M.bovis_AF2122/97           SAPSSLAVSLADASGITLVAFLRGDSMNVYTRADRIT-------
Rv2899c|M.tuberculosis_H37Rv        SAPSSLAVSLADASGITLVAFLRGDSMNVYTRADRIT-------
MMAR_1811|M.marinum_M               SAPSSLAVSLAEESGMTLVAFLREDSMNVYTRPDRIV-------
MUL_2059|M.ulcerans_Agy99           SAPSSLAVSLAEESGMTLVAFLREDSMNVYTRPDRIV-------
MAV_3753|M.avium_104                SAPSSLAVSLAEESGVTLVAFLREDSMNIYTRADRIG-------
TH_1165|M.thermoresistible__bu      SAPSSLAVDLAQRSGLTLIAFLRGASMNIYTRRDRVTV------
MSMEG_0165|M.smegmatis_MC2_155      SAPSSLAVDLAREMGLTLVGFLRGATMNIYAGAERISDDRFATV
                                    ********.**   *:**:.***  :**:*:  :*: