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ASRAGCSRPSCCGCRPWIRTTGSRDRRPHAGSGNRSCGADLLQHGVGITVVDLFRPPRIRRRGAAERRAR RLVRTPRTQATVSGAKAVGGFVKDNPLESALLVGGVALALTGVGGPAGAAAIAAATVNISSAAVDIAAAV MPDNQALGIASTCARRRVHGHPARRGQKGGRRGRRTRRRTTGQARRYVIDVAKAAPTPPAQLADEIAAAG TAKPPVKPGVSPKVPNAPPAKTAEATPTAATHNASDAAPSVGKAPEASPHAVPGGKTVGHCHQHAAIAEE RQEEQEAPQETRQVTKSPCTRSSPGLLEMGS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4606 | - | - | 100% (312) | hypothetical protein MSMEG_4606 |
| M. smegmatis MC2 155 | MSMEG_2148 | - | 7e-49 | 57.73% (194) | HNH endonuclease domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0699 | - | 3e-05 | 27.37% (179) | hypothetical protein MSMEG_0699 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0271 | - | 4e-05 | 22.12% (208) | hypothetical protein Mflv_0271 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1303c | - | 2e-06 | 29.71% (138) | hypothetical protein MAB_1303c |
| M. marinum M | MMAR_0611 | - | 8e-05 | 24.66% (296) | iron-sulphur-binding reductase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0574 | - | 1e-05 | 25.00% (292) | iron-sulphur-binding reductase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0611|M.marinum_M MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQPASGRTDDIGAR
MUL_0574|M.ulcerans_Agy99 MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQPASGRTDDIGAR
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0611|M.marinum_M IWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLFVENF
MUL_0574|M.ulcerans_Agy99 IWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLFVENF
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0611|M.marinum_M SIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASRFYGS
MUL_0574|M.ulcerans_Agy99 SIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASRFYGS
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0611|M.marinum_M HNSGAWLVLFMIFNVIWTYVLVRGSAVNNETLPYGKGAFLSQLFGAILRP
MUL_0574|M.ulcerans_Agy99 HNSGAWLVLFMIFNVIWTYVLVRGSAVNNETLPYGKGAFLSQLFAAILRP
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0611|M.marinum_M LGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVTFKRLPD
MUL_0574|M.ulcerans_Agy99 LGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVTFKRLPD
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0611|M.marinum_M GLGPLLPVEADGKPVDFENPPDDAIFGRGKIEDFTWKGMLDFATCTECGR
MUL_0574|M.ulcerans_Agy99 GLGPLLPVEADGKPVDFENPPDDAIFGRGKIEDFTWKGMLDFATCTECGR
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0611|M.marinum_M CQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEKTADPLEGLDLET
MUL_0574|M.ulcerans_Agy99 CQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEKTADLLEGLDLET
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0611|M.marinum_M AAEEGHHVPESGFGRVPGDGPEQAARPLVGTAEQGGVIDPDVLWSCVSCG
MUL_0574|M.ulcerans_Agy99 AAGEGHHVPESGFGRVPGDGPEQAARPLVGTAEQGGVIDPDVLWSCVSCG
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK -MRSCLGVSLGTANLVAVADGRATVRPAAVTVPSGLSVTGFVERVGDPVP
MMAR_0611|M.marinum_M ACVEQCPVDIEHIDHIVDMRRYQVMMESEFPSELSVLFKNLENKGNPWGQ
MUL_0574|M.ulcerans_Agy99 ACVEQCPVDIEHIDHIVDMRRYQVMMESEFPSELSVLFKNLENKGNPWGQ
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK LVLADHSVHRPETLAAAAVEDLTRWASPQRRPDLVTVAVPAHWSGAAIGA
MMAR_0611|M.marinum_M NASDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCAGAYDDKAKKTTK
MUL_0574|M.ulcerans_Agy99 NASDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCAGAYDDKAKKTTK
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK FRSAAPHVTVVSEVSAAVTALQASPGLPTRGVIALCDLGAGGSSITLVDA
MMAR_0611|M.marinum_M AVAELLATAGVKFMVLGAGETCNGDSARRSGNEFLFQQLAQQAIETLDGV
MUL_0574|M.ulcerans_Agy99 AVAELLATAGVKFMVLGAGETCNGDSARRSGNEFLFQQLAQQAIETLDGV
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK GNGFAPVGDTVRLDVLSG-DGVDGAVLQHVLAEIETDPGGTAHVAALSGL
MMAR_0611|M.marinum_M FEGVETVDRKVVVTCPHCFNTLGKEYRQLGSNYSVLHHTQLLNRLIRDKK
MUL_0574|M.ulcerans_Agy99 FEGVETVDRKVVVTCPHCFNTLGKEYRQLGSNYSVLHHTQLLNRLIRDKK
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK RDRCRAAKERLSVETATGLVWGRTTVRLTRPELEALIDDAVG-GFVDAVV
MMAR_0611|M.marinum_M LVPVTPVSQDVTYHDPCYLGRHNKVYEAPRELIGAAGANLAEMPRHAERS
MUL_0574|M.ulcerans_Agy99 LVPVTPVSQDVTYHDPCYLGRHNKVYEAPRELIGAAGANLAEMPRHAERS
MAB_1303c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 --------------MASRAGCSRPSCCGCRPWIRTTGS-RDRRPHAGSGN
Mflv_0271|M.gilvum_PYR-GCK TTLHRYGVSPAALAAVATVGGGARIPLVTERLSEALQRPVITTPGAALAA
MMAR_0611|M.marinum_M FCCGAGGARMWMEEHIGKRINHERVDEALATNASTIATACPFCRVMVTDG
MUL_0574|M.ulcerans_Agy99 FCCGAGGARMWMEEHIGKRINHERVDEAVATNASTIATACPFCRVMVTDG
MAB_1303c|M.abscessus_ATCC_199 ---------------------MSRITNVFMG-------------------
MSMEG_4606|M.smegmatis_MC2_155 RSCGADLLQHGVGITVVDLFRPPRIRRRGAAER-----------------
Mflv_0271|M.gilvum_PYR-GCK AAGAELLARRGAEPVAQTVSVAAPMTAANATVAAPVTP------------
:
MMAR_0611|M.marinum_M VNDRQEEAGRSGVEVLDVAQVLLGSLDREKATLPEKGTAAKEAEKRAKAA
MUL_0574|M.ulcerans_Agy99 VNDRQEEAGRSGVEVLDVAQVLLGSLDREKATLPEKGTAAKEAEKRAKTA
MAB_1303c|M.abscessus_ATCC_199 ----------ASIAAFASAGLALG-LASTASADPIPGPPPNPTNPAAILG
MSMEG_4606|M.smegmatis_MC2_155 ----------RARRLVRTPRTQATVSGAKAVGGFVKDNPLESALLVGGVA
Mflv_0271|M.gilvum_PYR-GCK -------LAWSAEADDPGAHAVFEDETVYATAYARPDVHFEPDEIDEADV
. . . :
MMAR_0611|M.marinum_M PKAAAPAAPAPAPAEAPAKAAEAPAAATAASPAAPAKGLGMAGGAKRPGA
MUL_0574|M.ulcerans_Agy99 PKAAAPAAPAPAPAEAPAKAAEASAAATAASPAAPAKGLGMAGGAKRPGA
MAB_1303c|M.abscessus_ATCC_199 QAASGFGNAPAAPAAVAAPAAPALPAVAPAAPAAPAVPG------AAPAA
MSMEG_4606|M.smegmatis_MC2_155 LALTGVGGPAGAAAIAAATVNISSAAVDIAAAVMPDNQALGIASTCARRR
Mflv_0271|M.gilvum_PYR-GCK EPLGWYRRPGVLFAAAACLAAVATTGLVLTAQVGPVEADASDIAAPVATA
. * ... . : .. :: . *
MMAR_0611|M.marinum_M KKAAPAPAAETAAAEAPAAPAKGLGMAAGAKKPGAKKAAAPTGETKPAEA
MUL_0574|M.ulcerans_Agy99 KKAAPAPAAETAAAEAPAAPAKGLGMAAGAKKPGAKKAAAPTGETKPAEA
MAB_1303c|M.abscessus_ATCC_199 PAVAPAPGAAPAVPGVPPAAAQGLTPAA---------AAALSPASVPATS
MSMEG_4606|M.smegmatis_MC2_155 VHGHPARRGQKGGRRGRRTRRRTTGQAR-----------RYVIDVAKAAP
Mflv_0271|M.gilvum_PYR-GCK PVQAPTMPVEIAPPPPPVTETVAAAPAPRVVQAAPQSPAPQRVVAKQAAP
*: . : * * .
MMAR_0611|M.marinum_M AAPAAPAAPVKGLGMASGAKRPGAKKAAPPAAAAPEAAATASAPEAAAAP
MUL_0574|M.ulcerans_Agy99 AAP---AAPVKGLGMASGAKRPGAKKAAPPAAAAPEAAATAPAPEAAAAP
MAB_1303c|M.abscessus_ATCC_199 NVP-----GVSQIPGAEGVTQTVDLWATNLPKLLPAGVQQTLIPPALVN-
MSMEG_4606|M.smegmatis_MC2_155 TPP---AQLADEIAAAGTAKPPVKPGVSPKVPNAPPAKTAEATPTAATHN
Mflv_0271|M.gilvum_PYR-GCK QAVPRPAAPATETVAAPAPSTTPTPTPTPSSTPTPTPSSTPTPTPTPSST
. * . . : * . :
MMAR_0611|M.marinum_M AEPAAPAAPVKGLGIATGAKRPGAKKAPARAEAPAAAAPAQPEPEATPEP
MUL_0574|M.ulcerans_Agy99 AEPAAPAAPVKGLGIATGAKRPGAKKAPARAEAPSAAAPAQPEPEATPEP
MAB_1303c|M.abscessus_ATCC_199 GIPAAAAAPAAGLPAAAAAT-PGAGLVPS---APMFAALP----------
MSMEG_4606|M.smegmatis_MC2_155 ASDAAPSVGKA--PEASPHAVPGGKTVGHCHQHAAIAEERQEEQEAPQET
Mflv_0271|M.gilvum_PYR-GCK PTPTPTPTPTP-TPTPTPTPTPTPTPTPTSTPAPTSTPPPVTSQPVPVET
:.... .: * . . :
MMAR_0611|M.marinum_M EPASKQDGEPTPPAAPAAPVKGLGMARGARPPGKR-----
MUL_0574|M.ulcerans_Agy99 EPASKQDGEPTPPAAPAAPVKGLGMARGARPPGKR-----
MAB_1303c|M.abscessus_ATCC_199 ----------------------------------------
MSMEG_4606|M.smegmatis_MC2_155 RQVTKSPCTRSSPGLLEMGS--------------------
Mflv_0271|M.gilvum_PYR-GCK PTATQEPAPAETPVTEIPVTETPATETPATECVPTAELAC