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AQRITAAELLDTLQNSARQIALLDLRSPLERSNGHIAVSAGLPWHDVEQHIADLVPLTSTPIVLASRPEL DERGAELLERLGYRDVSVLADGLDGWKSAGGRVYTGTNVRSKTLGEWIEHTYGTPTVDGETVDAWRAAGE DVVFLDSRTPAEYRHHHIPGGHNTGGGAEIAYRAAQVIDNAKTKVVINCQGRTRGIVGAQSLINTGIANP VFSLHNGTPAWQRSGRPLEYGAGSELPAPATVSPELTDWARRTLAEAGAVVIDIGQAQRYLDDTTSVTYL LDVRSPGEYAEGHFTAAVSAPGGQLVQATDDYVAVHRGRVVLADTADFVRAANTVQWLRYLHDGPLTVVA VNPDGTGGDLKRSNRLSIAAPEVPTVTAAELATLDSAQLVDVRSSSQYAAGHLRGSVHARREHLADIVAA ADGATVVLIGDADFAAEHLVAGLDGDVRVLAGGIEAVADQLTDADPRHAGEIADRTGPPDFGPERDAWYE AYFAWELALLKETEGDPFFDFEAVGGK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4589 | - | - | 100% (518) | fused rhodanese domain-containing protein/cystathionine beta-lyase |
| M. smegmatis MC2 155 | MSMEG_5386 | - | 2e-07 | 30.69% (101) | rhodanese-like domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0984 | - | 6e-05 | 27.10% (107) | rhodanese domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2142 | - | 1e-07 | 26.58% (237) | thiosulfate sulfurtransferase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4024 | - | 6e-06 | 25.95% (131) | rhodanese domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0984|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4024|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4589|M.smegmatis_MC2_155 MAQRITAAELLDTLQNSARQIALLDLRSPLERSNGHIAVSAGLPWHDVEQ
MAV_2142|M.avium_104 --------------------------------------------------
Mflv_0984|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4024|M.vanbaalenii_PYR-1 ----------------------------------------------MERY
MSMEG_4589|M.smegmatis_MC2_155 HIADLVPLTSTPIVLASRPELDERGAELLERLGYRDVSVLADGLDGWKSA
MAV_2142|M.avium_104 ---------------------------------------------MGARD
Mflv_0984|M.gilvum_PYR-GCK ---------------------MTAPVTIDSHDLSQMLGSPTPPRVLDVRT
Mvan_4024|M.vanbaalenii_PYR-1 PPRYHASRGFRHQQLRKGLTSMTAPATIDSHDLHQMLGSATPPRVLDVRT
MSMEG_4589|M.smegmatis_MC2_155 GGRVYTGTNVRSKTLGEWIEHTYGTPTVDGETVDAWRAAGEDVVFLDSRT
MAV_2142|M.avium_104 QVLITATELADVIEAGDPVSILDVRWRLDEPDGRAAYLQGHLPGAVYVSL
:* :
Mflv_0984|M.gilvum_PYR-GCK PGEFETAHIAG--AYNVP-LDLLREHRDEIVKHLDEDVVLVCRSGQRAAQ
Mvan_4024|M.vanbaalenii_PYR-1 PGEFETAHING--AYNVP-LDLLREHRDEIIGHLDQDVVLVCRSGQRAAQ
MSMEG_4589|M.smegmatis_MC2_155 PAEYRHHHIPG--GHNTGGGAEIAYRAAQVIDNAKTKVVINCQGRTRGIV
MAV_2142|M.avium_104 EDELSDHTVSGRGRHPLPSGPSLQAAARRWGIRQDTPVVVYDDWNRAGSA
* : * : : . . . **: .
Mflv_0984|M.gilvum_PYR-GCK AEETLRNAGLSN-VHILDGGITAWEAKGFAVNRGA------------QRW
Mvan_4024|M.vanbaalenii_PYR-1 AEETLRNTGLTN-VHILDGGITAWEAQGFAVNRGA------------TRW
MSMEG_4589|M.smegmatis_MC2_155 GAQSLINTGIANPVFSLHNGTPAWQRSGRPLEYGAGSELPAPATVSPELT
MAV_2142|M.avium_104 RAWWLLRAAGLDNVRILDGGLAAWRAAGGRLVSGP---------------
* .:. : * *..* .**. * : *.
Mflv_0984|M.gilvum_PYR-GCK DLERQVRLVAGSIVLSS-----------------------------ILGS
Mvan_4024|M.vanbaalenii_PYR-1 DLERQVRLVAGSLVLTA-----------------------------ILGS
MSMEG_4589|M.smegmatis_MC2_155 DWARRTLAEAGAVVIDIGQAQRYLDDTTSVTYLLDVRSPGEYAEGHFTAA
MAV_2142|M.avium_104 -----VEPAPGNVTVPHD----------------------------DLHS
. .* :.: :
Mflv_0984|M.gilvum_PYR-GCK IAAP--------------------------------KLKWVAGAVGGGLT
Mvan_4024|M.vanbaalenii_PYR-1 IAAP--------------------------------KLKWLAAGVGGGLT
MSMEG_4589|M.smegmatis_MC2_155 VSAPGGQLVQATDDYVAVHRGRVVLADTADFVRAANTVQWLRYLHDGPLT
MAV_2142|M.avium_104 GNRP--------------------------------TVTTEQVTAGAATL
* .: ..
Mflv_0984|M.gilvum_PYR-GCK FAALS--------------------------------NTCAMGMLLSKLP
Mvan_4024|M.vanbaalenii_PYR-1 FAAVS--------------------------------NTCAMGTLLSKLP
MSMEG_4589|M.smegmatis_MC2_155 VVAVNPDGTGGDLKRSNRLSIAAPEVPTVTAAELATLDSAQLVDVRSSSQ
MAV_2142|M.avium_104 IDARAPERYRG--------------------------EMEPLDPVAGHIP
. * : : : .
Mflv_0984|M.gilvum_PYR-GCK YNRG-ASCDAEGIVAQLVEGSAS---------------------------
Mvan_4024|M.vanbaalenii_PYR-1 YNRGTATCDAHTIVTQLVDANTTDKNKKVS--------------------
MSMEG_4589|M.smegmatis_MC2_155 YAAGHLRGSVHARREHLADIVAAADGATVVLIGDADFAAEHLVAGLDGDV
MAV_2142|M.avium_104 GAENLPSGDVLAADGTFLDDDALARVFAEHRIERHGAVAAYCGSGVTATV
. .. : : :
Mflv_0984|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4024|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4589|M.smegmatis_MC2_155 RVLAGGIEAVADQLTDADPRHAGEIADRTGPPDFGPERDAWYEAYFAWEL
MAV_2142|M.avium_104 TIAALAAVGRTAALYPG--SWSEWCADPARPVERGGA-------------
Mflv_0984|M.gilvum_PYR-GCK --------------------
Mvan_4024|M.vanbaalenii_PYR-1 --------------------
MSMEG_4589|M.smegmatis_MC2_155 ALLKETEGDPFFDFEAVGGK
MAV_2142|M.avium_104 --------------------