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DMLYSLGISAAAAVTLAWLAIRNIRVVRQYERGVVFRFGRVTKSIRQPGLTMLIPIADRLQKVNMQIVTM PIPAQDGITRDNVTVRVDAVIYFKVIDPVRAVVDVQDYMSAVGQVAQTSLRSIIGKSNLDDLLSNRERLN QGLELLIDNPAVGWGIHIDRVEIKDVVLPDSMKRSIAKQAEAERERRARVITADGELQASEKLAAAADVM GNEPAALQLRFLETVVEVAAEKNSTVVVPFPVELLRFLDRVTPHESARNGGPVPRVV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4576 | - | - | 100% (268) | SpfH domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3155 | - | 6e-32 | 35.33% (184) | band 7 protein |
| M. smegmatis MC2 155 | MSMEG_1517 | - | 2e-06 | 22.60% (177) | SPFH domain-containing protein/band 7 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1524 | - | 1e-30 | 33.33% (204) | hypothetical protein Mb1524 |
| M. gilvum PYR-GCK | Mflv_3653 | - | 1e-31 | 33.50% (203) | band 7 protein |
| M. tuberculosis H37Rv | Rv1488 | - | 1e-30 | 33.33% (204) | hypothetical protein Rv1488 |
| M. leprae Br4923 | MLBr_01802 | - | 1e-29 | 32.84% (201) | hypothetical protein MLBr_01802 |
| M. abscessus ATCC 19977 | MAB_2718c | - | 1e-32 | 35.26% (190) | hypothetical protein MAB_2718c |
| M. marinum M | MMAR_2294 | - | 5e-31 | 32.20% (205) | hypothetical protein MMAR_2294 |
| M. avium 104 | MAV_4013 | - | 4e-64 | 49.17% (240) | SPFH domain-containing protein/band 7 family protein |
| M. thermoresistible (build 8) | TH_2726 | - | 1e-61 | 47.64% (233) | PUTATIVE spfh domain/band 7 family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1071 | - | 1e-112 | 76.23% (265) | band 7 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1524|M.bovis_AF2122/97 ---------MQGAVAGLVFLAVLVIFAIIVVAKSVALIPQAEAAVIERLG
Rv1488|M.tuberculosis_H37Rv ---------MQGAVAGLVFLAVLVIFAIIVVAKSVALIPQAEAAVIERLG
MMAR_2294|M.marinum_M ---------MDDAVVGLVFLAVLVIFAIIVVAKSVALIPQAEAAVIERLG
MLBr_01802|M.leprae_Br4923 ---------MQGVVAGLVLLAVLTIFAIVVVAKSIVLIPQAEAAVVERLG
Mflv_3653|M.gilvum_PYR-GCK ---------MDGALAGLVLLAVLVVFAAVIVAKSVALIPQAEAAVIERLG
MAB_2718c|M.abscessus_ATCC_199 ----------MGVAAGVFVLIVLIILGVTIVLKSVALVPQAEAAVIERLG
MSMEG_4576|M.smegmatis_MC2_155 -------MD---MLYSLGISAAAAVTLAWLAIRNIRVVRQYERGVVFRFG
Mvan_1071|M.vanbaalenii_PYR-1 MPRRDPGWDGGVMIILYAVAGVVTLTLLSLLGASVRVIQQFERGVVYRFG
MAV_4013|M.avium_104 -----------MTTLVIALIGAGIVVLVVLGFWSLVVLREYERGVVFRMG
TH_2726|M.thermoresistible__bu -----------MSGWPAVVIVLAVVVSAVA-VASLRIVKEYERGVAFRLG
. : .: :: : * .* *:*
Mb1524|M.bovis_AF2122/97 RYSRTVS-GQLTLLVPFIDRVRARVDLRERVVSFPPQPVITEDNLTLNID
Rv1488|M.tuberculosis_H37Rv RYSRTVS-GQLTLLVPFIDRVRARVDLRERVVSFPPQPVITEDNLTLNID
MMAR_2294|M.marinum_M RYSRTVS-GQLTLLVPFIDRVRARVDLRERVVSFPPQPVITEDNLTLNID
MLBr_01802|M.leprae_Br4923 RYGRTVS-GQLTLLVLFIDRVRARVDLRERVVSFPPQPVITEDNLTLNID
Mflv_3653|M.gilvum_PYR-GCK RYSKTVS-GQLTLLLPFVDKIRARVDLRERVVSFPPQPVITEDNLTVNID
MAB_2718c|M.abscessus_ATCC_199 RYSKTVS-GQLTILVPFVDRIRAKVDLRERVVSFPPQPVITEDNLTVNID
MSMEG_4576|M.smegmatis_MC2_155 RVTKSIRQPGLTMLIPIADRLQK-VNMQIVTMPIPAQDGITRDNVTVRVD
Mvan_1071|M.vanbaalenii_PYR-1 KVQSRVREPGLTLLVPIADRLQK-VNMQIITMPVPAQDGITRDNVTVRVD
MAV_4013|M.avium_104 HARPLYG-PGLRFLIPLLDKMIR-VDQRLVTLTIPPQEVITRDNVPARVN
TH_2726|M.thermoresistible__bu RLRGPLG-PGIVVVLPGIDKMVR-VDLRTVTLTIPPQEVITRDNVTARVN
: : .:: *:: *: : .:..*.* **.**:. .::
Mb1524|M.bovis_AF2122/97 TVVYFQVTVPQAAVYEISNYIVGVEQLTTTTLRNVVGGMTLEQTLTSRDQ
Rv1488|M.tuberculosis_H37Rv TVVYFQVTVPQAAVYEISNYIVGVEQLTTTTLRNVVGGMTLEQTLTSRDQ
MMAR_2294|M.marinum_M TVVYFQVTVPQAAVYEISNYIVGVEQLATTTLRNVVGGMTLEQTLTSRDQ
MLBr_01802|M.leprae_Br4923 TVVYFQVTVPQAAVYEISNYIVGVEQLTTTTLRNVVGGMTLEQTLTSRDQ
Mflv_3653|M.gilvum_PYR-GCK TVVYFQVTNPQAAVYQISNYIVGVEQLTTTTLRNVVGGMTLEQTLTSRDS
MAB_2718c|M.abscessus_ATCC_199 TVVYFQVTNPQAAVYEISNYIVGVEQLTTTTLRNVVGGMTLEQTLTSRDQ
MSMEG_4576|M.smegmatis_MC2_155 AVIYFKVIDPVRAVVDVQDYMSAVGQVAQTSLRSIIGKSNLDDLLSNRER
Mvan_1071|M.vanbaalenii_PYR-1 AVIYFKVADPVRAVVDVQNYMSAIGQVAQTSLRSIIGKSNLDDLLSNREH
MAV_4013|M.avium_104 AVVMFQVTDPRKAILAVENYAVATSQIAQTTLRSLLGRADLDTLLAHRED
TH_2726|M.thermoresistible__bu AVVLFRVTDPVKSVMAVENFAVATSQIAQTTLRSVVGRADLDTLLAHRAD
:*: *:* * :: :.:: . *:: *:**.::* *: *: *
Mb1524|M.bovis_AF2122/97 INAQLRGVLDEATGRWGLRVARVELRSIDPPPSIQASMEKQMKADREKRA
Rv1488|M.tuberculosis_H37Rv INAQLRGVLDEATGRWGLRVARVELRSIDPPPSIQASMEKQMKADREKRA
MMAR_2294|M.marinum_M INGQLRGVLDEATGRWGLRVARVELRSIDPPPSIQASMEKQMKADREKRA
MLBr_01802|M.leprae_Br4923 INAQLRGVLDEATGRWGLRVARVELRSIDPPPSIQTSMEKQMKADREKRA
Mflv_3653|M.gilvum_PYR-GCK INGQLRGVLDEATNRWGLRVARVELRSIDPPPSIQDSMEKQMRADREKRA
MAB_2718c|M.abscessus_ATCC_199 INGQLRGVLDEATGRWGLRVARVELRSIDPPPSVQESMEKQMKADREKRA
MSMEG_4576|M.smegmatis_MC2_155 LNQGLELLIDNPAVGWGIHIDRVEIKDVVLPDSMKRSIAKQAEAERERRA
Mvan_1071|M.vanbaalenii_PYR-1 LNQGLELMIDSPALGWGIHIDRVEIKDVILPDSMKRSIARQAEAERERRA
MAV_4013|M.avium_104 LNNDLRTIIDKQTEPWGVQVHVVEIKDVEIPESMQRAMAREAEAERERRA
TH_2726|M.thermoresistible__bu LNEDLAASIARQTEPWGIRVEVVEIKDVEIPEMMQRAMAREAEAERERRA
:* * : : **::: **::.: * :: :: :: .*:**:**
Mb1524|M.bovis_AF2122/97 MILTAEGTREAAIKQAEGQKQAQILAAEGAKQAAILAAEADRQSRMLRAQ
Rv1488|M.tuberculosis_H37Rv MILTAEGTREAAIKQAEGQKQAQILAAEGAKQAAILAAEADRQSRMLRAQ
MMAR_2294|M.marinum_M MILTAEGTREAAIKQAEGQKQSQILAAEGAKQAAILAAEADRQSRMLRAQ
MLBr_01802|M.leprae_Br4923 MILTAEGTREAAIKQAEGNKQAQILAAEGAKQAVILAAEADRQSRMLRAQ
Mflv_3653|M.gilvum_PYR-GCK MILTAEGSREAAIKQAEGQKQAQILAAEGAKQASILAAEGDRQSRMLRAQ
MAB_2718c|M.abscessus_ATCC_199 MILNAEGVREASIKQAEGAKQSQILAAEGAKQAAILSAEADRQSRILRAE
MSMEG_4576|M.smegmatis_MC2_155 RVITADG-------------------------------------------
Mvan_1071|M.vanbaalenii_PYR-1 RVITADG-------------------------------------------
MAV_4013|M.avium_104 KVINARG-------------------------------------------
TH_2726|M.thermoresistible__bu KVISARG-------------------------------------------
::.* *
Mb1524|M.bovis_AF2122/97 GERAAAYLQAQGQAKAIEKTFAAIKAGRPTPEMLAYQYLQTLPEMARG-D
Rv1488|M.tuberculosis_H37Rv GERAAAYLQAQGQAKAIEKTFAAIKAGRPTPEMLAYQYLQTLPEMARG-D
MMAR_2294|M.marinum_M GERAAAYLRAQGEAKAIQKTFAAIKAGRPTPEMLAYQYLQTLPEMARG-D
MLBr_01802|M.leprae_Br4923 GKRAAAYLQAQGQAKAIEKTFAAIKAGRPTPEMLAYQYLQILPQMARG-D
Mflv_3653|M.gilvum_PYR-GCK GERAAAYLQAQGQAKAIEKTFAAIKAGRPTPEMLAYQYLQTLPQMAKG-E
MAB_2718c|M.abscessus_ATCC_199 GERAAQYLQAQGQAKAIEKVFAAVKSGKPTPELLAYQYLQTLPKMAEG-E
MSMEG_4576|M.smegmatis_MC2_155 ------------ELQASEKLAAAADVMGNEPAALQLRFLETVVEVAAEKN
Mvan_1071|M.vanbaalenii_PYR-1 ------------ELQASQKLASAACVMSEQPAALQLRLLQTVVEVAAEKN
MAV_4013|M.avium_104 ------------ELQASEELREAAETLSKSPASLQLRYLQTLLELGADQN
TH_2726|M.thermoresistible__bu ------------ELQASAELRDAAVTLSESPASLQLRYLQTLLELGADQN
: :* : * * * : *: : ::. :
Mb1524|M.bovis_AF2122/97 ANKVWVVPSDFNAALQGFTRLLGKPGEDGVFRFEPSPVEDQP---KHAAD
Rv1488|M.tuberculosis_H37Rv ANKVWVVPSDFNAALQGFTRLLGKPGEDGVFRFEPSPVEDQP---KHAAD
MMAR_2294|M.marinum_M ANKVWVVPSDFNAALQGFTRMLGKPGEDGVFRFEASPVEDLP---KHATD
MLBr_01802|M.leprae_Br4923 ANKVWVVPSDFSTALQGFTKLLGAPGEDGVFRFQPSPVDSSDQVVKHAAD
Mflv_3653|M.gilvum_PYR-GCK ANKVWLVPSDFGSALQGFTKLLGAPGEDGVFRYTPSPVDDAG----TRPE
MAB_2718c|M.abscessus_ATCC_199 ANKVWLIPSDFGSALQGFTKLLGAPGDDGVFRYEPSPVDTST----ERPE
MSMEG_4576|M.smegmatis_MC2_155 STVVVPFPVELLRFLDRVTPHESARN-GGPVPRVV---------------
Mvan_1071|M.vanbaalenii_PYR-1 STLVLPFPVELLRFLERSTPQAQSDGPADDVARSIAAKAADGIGLLRLDE
MAV_4013|M.avium_104 STVVFPLPVDIITPFLR-----NPELLQGVVDNVGRPG------------
TH_2726|M.thermoresistible__bu STVVFPLPIDIIGPFVEGVRRIRAEGLQQDAPGDGVPHIRR----VRSDE
:. * .* :: :
Mb1524|M.bovis_AF2122/97 GDDAEVAGWFSTDTDPSIARAVATAEAIARKPVEGSLGTPPRLTQ-----
Rv1488|M.tuberculosis_H37Rv GDDAEVAGWFSTDTDPSIARAVATAEAIARKPVEGSLGTPPRLTQ-----
MMAR_2294|M.marinum_M GDDDEVSDWFSTETDPAIAQAVAKAEAIARKPVEGPLASPPELGPYNR--
MLBr_01802|M.leprae_Br4923 EDDAEVADWFSVETDPAIAQAVAKAEAMVYQPVDE---------------
Mflv_3653|M.gilvum_PYR-GCK DDSDEVADWFSTETDPVIAQAVAKAEAEARAPVPGALDGPKQYPPLSQQV
MAB_2718c|M.abscessus_ATCC_199 DDSDEVAGWFDTKATPEAAAAVAEAQSAAKEIGQIDPVSRHQLPEV----
MSMEG_4576|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1071|M.vanbaalenii_PYR-1 PATGSRVAT-----------------------------------------
MAV_4013|M.avium_104 --------------------------------------------------
TH_2726|M.thermoresistible__bu --------------------------------------------------
Mb1524|M.bovis_AF2122/97 ------------------
Rv1488|M.tuberculosis_H37Rv ------------------
MMAR_2294|M.marinum_M ------------------
MLBr_01802|M.leprae_Br4923 ------------------
Mflv_3653|M.gilvum_PYR-GCK QPTATDYAQQPRHGSPDQ
MAB_2718c|M.abscessus_ATCC_199 ------------------
MSMEG_4576|M.smegmatis_MC2_155 ------------------
Mvan_1071|M.vanbaalenii_PYR-1 ------------------
MAV_4013|M.avium_104 ------------------
TH_2726|M.thermoresistible__bu ------------------