For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VGTHALRIAHGTRRFGGTPALADIDLQIHTGEFLAVLGPSGSGKSTLLRICAGLDALTSGTLTWSGDGSR PRTGVVFQQPLLMPWLTVADNVAFARRFTAQRKGFDPGYAARLITRFGLDDLADRYPDELSGGQAQRVAI LRAVATRPQLLLLDEPFSALDPATRGDLAGWLRDLARELDVTVVLVTHDVDEALALAQRIVLLDAGSIRA EWTVRGDGLPTRSEILAHYRADPAVEVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4520 | - | - | 100% (238) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_4530 | cysA | 6e-42 | 46.70% (212) | sulfate ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_0551 | - | 3e-41 | 47.21% (197) | ABC nitrate/sulfonate/bicarbonate transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 3e-43 | 46.70% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_1083 | - | 1e-41 | 46.31% (203) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 3e-43 | 46.70% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 3e-32 | 38.19% (199) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2461 | - | 3e-73 | 66.35% (208) | putative sulfate ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_3715 | cysA1 | 4e-41 | 45.07% (213) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 2e-41 | 46.01% (213) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_2424 | - | 5e-42 | 45.75% (212) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 6e-42 | 45.54% (213) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_3872 | - | 5e-43 | 46.23% (212) | sulfate ABC transporter, ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4520|M.smegmatis_MC2_155 -------------MGTHALRIAHGTRRFG-GTPALADIDLQIHTGEFLAV
MAB_2461|M.abscessus_ATCC_1997 -----------------------------------------MATGEFLAI
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTAL
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTAL
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTAL
MUL_3658|M.ulcerans_Agy99 ------MTGPGT--GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTAL
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYG-DFVALDHVDFVVPTGSLTAL
TH_2424|M.thermoresistible__bu ------MT--------DAITVRGANKRYG-DFAALDNVDFAVPAGSLTAL
Mvan_3872|M.vanbaalenii_PYR-1 ------MT--------HAITVEGANKRYG-DFAALDNVDFVVPAGSLTAL
Mflv_1083|M.gilvum_PYR-GCK ------MTNRG-----VGVQFDELTRVYG-ATRALDGLTLHIEPGELVAL
MLBr_01089|M.leprae_Br4923 ---------------MAEIVLEHVNKNYPNGATAVHDLSITVADGEFLIL
: *.: :
MSMEG_4520|M.smegmatis_MC2_155 LGPSGSGKSTLLRICAGLDALTSGTLTWSG------DGSRPRTGVVFQQP
MAB_2461|M.abscessus_ATCC_1997 LGPSGSGKSTLLRVLAGLEELSAGAVVWAS------DEGRPRTGVVFQDA
Mb2419c|M.bovis_AF2122/97 LGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHY
Rv2397c|M.tuberculosis_H37Rv LGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHY
MMAR_3715|M.marinum_M LGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHY
MUL_3658|M.ulcerans_Agy99 LGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHY
MAV_1785|M.avium_104 LGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQRRGIGFVFQHY
TH_2424|M.thermoresistible__bu LGPSGSGKSTLLRAIAGLDRPDTGTITINGRDVTDVPPQRRGIGFVFQHY
Mvan_3872|M.vanbaalenii_PYR-1 LGPSGSGKSTLLRAIAGLDEPDTGTITINGRDVTRIPPQKRGIGFVFQHY
Mflv_1083|M.gilvum_PYR-GCK LGPSGGGKTTALRILAGLDEATSGTVSVGGVDVGRVPANKRDMGMVFQAY
MLBr_01089|M.leprae_Br4923 IGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPKDRDIAMVFQSY
:**** **:* *. ***: :* : . ..***
MSMEG_4520|M.smegmatis_MC2_155 LLMPWLTVADNVAFARRFTAQRKGFDPGYAARLITRFGLDDLADRYPDEL
MAB_2461|M.abscessus_ATCC_1997 LLMPWLTVAENIAFAKRFGAHRSGFDDAYVDNLVRHFGLQQLSVRYPDQL
Mb2419c|M.bovis_AF2122/97 AAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQL
Rv2397c|M.tuberculosis_H37Rv AAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQL
MMAR_3715|M.marinum_M AAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPNQL
MUL_3658|M.ulcerans_Agy99 AAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPDQL
MAV_1785|M.avium_104 AAFKHLTVRDNVAYGLKVRKRPKAEIKAKVDNLLEVVGLSGFQGRYPNQL
TH_2424|M.thermoresistible__bu AAFKHLTVRDNVAFGLKIRRRPKREIAEKVDNLLEVVGLAGFQNRYPNQL
Mvan_3872|M.vanbaalenii_PYR-1 AAFKHLTVRDNVAFGLKIRKKPKAEIKAKVDDLLEVVGLAGFQSRYPNQL
Mflv_1083|M.gilvum_PYR-GCK SLFPHLTVLDNVAFGLKMRGKGKSDRLSRAADMLDLVGLGELGGRYANEL
MLBr_01089|M.leprae_Br4923 ALYPHMTVRQNIAFPLMLAKVKKAEIAQKVSETAQILDLTDLLDRKPSQL
:** :*:*: . . . ..* : * ..:*
MSMEG_4520|M.smegmatis_MC2_155 SGGQAQRVAILRAVATRPQLLLLDEPFSALDPATRGDLAGWLRDLARELD
MAB_2461|M.abscessus_ATCC_1997 SGGQAQRVAILRAAATRPGLLLLDEPFSALDPVTRADLQAWLQNLADELA
Mb2419c|M.bovis_AF2122/97 SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVH
Rv2397c|M.tuberculosis_H37Rv SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVH
MMAR_3715|M.marinum_M SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVH
MUL_3658|M.ulcerans_Agy99 SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVH
MAV_1785|M.avium_104 SGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVH
TH_2424|M.thermoresistible__bu SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRTWLRRLHEEVH
Mvan_3872|M.vanbaalenii_PYR-1 SGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVH
Mflv_1083|M.gilvum_PYR-GCK SGGQQQRVALARALAIRPRVLLLDEPLSALDAKVRTQLRDEIRRVQLEVG
MLBr_01089|M.leprae_Br4923 SGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQRRLG
**** **:*: ** . * :*:***:. **. * : : .:
MSMEG_4520|M.smegmatis_MC2_155 VTVVLVTHDVDEALALAQRIVLL-DAGSIRAEWTVR----GDGLPTRSEI
MAB_2461|M.abscessus_ATCC_1997 VTVVLVTHDVDEALNLAHRVILLGDDGRIRQEWVLGDEGAGDRAQIRGQI
Mb2419c|M.bovis_AF2122/97 VTTVLVTHDQAEALDVADRIAVL-HKGRIEQVGSPTDVYDAPANAFVMSF
Rv2397c|M.tuberculosis_H37Rv VTTVLVTHDQAEALDVADRIAVL-HKGRIEQVGSPTDVYDAPANAFVMSF
MMAR_3715|M.marinum_M VTTVLVTHDQAEALDVADRIAVL-NSGRIEQVGSPTEVYDAPANAFVMSF
MUL_3658|M.ulcerans_Agy99 VTTVLVTHDQAEALDVADRIAVL-NSGRIEQVGSPTEVYDAPTNAFVMSF
MAV_1785|M.avium_104 VTTVLVTHDQAEALDVADRIAVL-NQGRIEQIGSPTEVYDAPTNAFVMSF
TH_2424|M.thermoresistible__bu VTTVLVTHDQSEALDVADRIAVL-NNGRIEQVGSPAEVYDSPANEFVMSF
Mvan_3872|M.vanbaalenii_PYR-1 VTTVLVTHDQQEALDVADRIAVL-NKGRIEQVGSPTEVYDAPANAFVMSF
Mflv_1083|M.gilvum_PYR-GCK TTTLFVTHDQEEALAVADRVGVM-NQGRLEQLAAPADLYAHPATPFVADF
MLBr_01089|M.leprae_Br4923 ATTVYVTHDQTEAMTLGDRVVVM-RSGVVQQIGTPDELYERPVNLFVAGF
.*.: **** **: :..*: :: * :. :
MSMEG_4520|M.smegmatis_MC2_155 LA---------------------------HYRADPAVEVS----------
MAB_2461|M.abscessus_ATCC_1997 LA---------------------------QYQPIEAAAQ-----------
Mb2419c|M.bovis_AF2122/97 LG---------------------------AVSTLNGSLVRPHDIRVGRTP
Rv2397c|M.tuberculosis_H37Rv LG---------------------------AVSTLNGSLVRPHDIRVGRTP
MMAR_3715|M.marinum_M LG---------------------------AVSALNGALVRPHDIRVGRTP
MUL_3658|M.ulcerans_Agy99 LG---------------------------AVSALNGALVRPHDIRVGRTP
MAV_1785|M.avium_104 LG---------------------------AVSTLNGTLVRPHDIRVGRTP
TH_2424|M.thermoresistible__bu LG---------------------------AVSSLNGTLVRPHDIWVGRHP
Mvan_3872|M.vanbaalenii_PYR-1 LG---------------------------AVSSLNGVLVRPHDIRVGRSP
Mflv_1083|M.gilvum_PYR-GCK VG---------------------------LNNKVPASVSGGTATLLG---
MLBr_01089|M.leprae_Br4923 IGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIVGVRP
:. .
MSMEG_4520|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2461|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 NMAVAAADGTAGSTGVLRAVVDRVVVLGFEVR-VELTSAATGGAFT-AQI
Rv2397c|M.tuberculosis_H37Rv NMAVAAADGTAGSTGVLRAVVDRVVVLGFEVR-VELTSAATGGAFT-AQI
MMAR_3715|M.marinum_M EMAVAAADGTGESTGVTRAVVDRIVVLGFEVR-VELTSAATGGAFT-AQI
MUL_3658|M.ulcerans_Agy99 EMAVAAADGTGESTGVTRAVVDRIVVLGFEVR-VELTSAATGGAFT-AQI
MAV_1785|M.avium_104 EMAVAAEDGTAESTGVARAIVDRVVKLGFEVR-VELTSAATGGPFT-AQI
TH_2424|M.thermoresistible__bu ELPT--SDSTLQATGVVRARIDRVVMLGFEVR-LELTSATNNAPFT-AQI
Mvan_3872|M.vanbaalenii_PYR-1 EMAIGASDDSVQATGVTRATIDRIVVLGFEVR-VELTSAATHTPFT-AQI
Mflv_1083|M.gilvum_PYR-GCK -VSVPALPGSVDGDGVAMVRPEAVTVAADPAGTATVATVSFLGAITRVGI
MLBr_01089|M.leprae_Br4923 EHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCDVYSAQL
MSMEG_4520|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2461|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 TRGDAEALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST-
Rv2397c|M.tuberculosis_H37Rv TRGDAEALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST-
MMAR_3715|M.marinum_M TRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTPSAAQI
MUL_3658|M.ulcerans_Agy99 TRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTPRAAQI
MAV_1785|M.avium_104 TRGDAEALALREGDTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA-
TH_2424|M.thermoresistible__bu TRGDAEALGLRSGDTVYVRATRVP----------ALPTGDVDERVAAR--
Mvan_3872|M.vanbaalenii_PYR-1 TRGDAEALGLKEGDTVYVRATRVP----------SLPDG-VPLPVA----
Mflv_1083|M.gilvum_PYR-GCK TMPDGSLLSAQMSSTAARALTPGDPVTV------GVEPGGVLVTRPL---
MLBr_01089|M.leprae_Br4923 DELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSGVNL
MSMEG_4520|M.smegmatis_MC2_155 --------
MAB_2461|M.abscessus_ATCC_1997 --------
Mb2419c|M.bovis_AF2122/97 --------
Rv2397c|M.tuberculosis_H37Rv --------
MMAR_3715|M.marinum_M GVGGQ---
MUL_3658|M.ulcerans_Agy99 GVGGQ---
MAV_1785|M.avium_104 --------
TH_2424|M.thermoresistible__bu --------
Mvan_3872|M.vanbaalenii_PYR-1 --------
Mflv_1083|M.gilvum_PYR-GCK --------
MLBr_01089|M.leprae_Br4923 TVSAPTDA