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TSQHTAGTEPAPAANDTELSARFVNETLPYMSQLRSRARRLTRNPVDAEDLVQETMLRAYTGFGTFREGT NLRAWLLHIMTNTYISGLRRARRRPSEYLCDHTSDHQMAAQDRRSQSAELDALDALPNIELAGALATLPE QFRLAIYYRDVVGLRYREIAEIMACSEGTIMSRLYRGRRRLRLLLAAGAT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4405 | - | - | 100% (191) | putative ECF sigma factor RpoE1 |
| M. smegmatis MC2 155 | MSMEG_1914 | - | 9e-53 | 54.84% (186) | RNA polymerase sigma-70 factor, family protein |
| M. smegmatis MC2 155 | MSMEG_3485 | - | 2e-45 | 53.57% (168) | putative ECF sigma factor RpoE1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3250c | sigH | 6e-52 | 53.48% (187) | RNA polymerase sigma factor RpoE |
| M. gilvum PYR-GCK | Mflv_4689 | - | 4e-51 | 50.75% (201) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3223c | sigH | 6e-52 | 53.48% (187) | RNA polymerase sigma factor RpoE |
| M. leprae Br4923 | MLBr_01076 | sigE | 7e-17 | 35.86% (145) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_3543c | - | 8e-51 | 53.37% (193) | RNA polymerase sigma-E factor |
| M. marinum M | MMAR_1334 | sigH | 4e-52 | 53.40% (191) | alternative RNA polymerase sigma-E factor (sigma- 24) SigH |
| M. avium 104 | MAV_4171 | - | 2e-50 | 51.01% (198) | RNA polymerase sigma factor RpoE |
| M. thermoresistible (build 8) | TH_0665 | sigH | 2e-49 | 52.97% (185) | ALTERNATIVE RNA POLYMERASE SIGMA-E FACTOR (SIGMA-24) SIGH |
| M. ulcerans Agy99 | MUL_2545 | sigH | 2e-51 | 52.88% (191) | RNA polymerase sigma factor RpoE |
| M. vanbaalenii PYR-1 | Mvan_1778 | - | 1e-51 | 53.48% (187) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4689|M.gilvum_PYR-GCK ------------MVPVMAMKAPSRSVFVLDVIGG-AATEGTVFPTMTD--
Mvan_1778|M.vanbaalenii_PYR-1 ----------------MAMEAPSRSVHVLDVIGG-AATEGTVFPTMTD--
TH_0665|M.thermoresistible__bu ---------------------------------------------MTD--
Mb3250c|M.bovis_AF2122/97 ---------------------------------------------MAD--
Rv3223c|M.tuberculosis_H37Rv ---------------------------------------------MAD--
MMAR_1334|M.marinum_M ------MSTSTSLLGEERLGRFPASPASVATLSGGTSTEGTVFIKMAD--
MUL_2545|M.ulcerans_Agy99 ---------------------------------------------MAD--
MAV_4171|M.avium_104 -----MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSP
MAB_3543c|M.abscessus_ATCC_199 -------------------MACLERPMSVPIRMVGVATERTAVTSMDS--
MSMEG_4405|M.smegmatis_MC2_155 ---------------------------------------------MTS--
MLBr_01076|M.leprae_Br4923 MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSPT
: .
Mflv_4689|M.gilvum_PYR-GCK --TNGLAASPAPADAG--------EAREETDAELTARFERDAIPLLDQLY
Mvan_1778|M.vanbaalenii_PYR-1 --ITGSAAEATLDGEA--------PAREETDAELTARFERDAIPLLDQLY
TH_0665|M.thermoresistible__bu --IEGTTPIRS----------------EESDAELTARFERDAIPLLDQLY
Mb3250c|M.bovis_AF2122/97 --IDGVTGSAGLQP----------GPSEETDEELTARFERDAIPLLDQLY
Rv3223c|M.tuberculosis_H37Rv --IDGVTGSAGLQP----------GPSEETDEELTARFERDAIPLLDQLY
MMAR_1334|M.marinum_M --IDGVTLAEAPDP----------EPPEETDEQLTARFERDAIPLLDQLY
MUL_2545|M.ulcerans_Agy99 --IDGVTLAEAPDP----------EPPEETDEQLTACFERDAIPLLDQLY
MAV_4171|M.avium_104 DGPDGVTSPEVPEAHAEPAAH--EETREETDAELTARFERDAIPLLDQLY
MAB_3543c|M.abscessus_ATCC_199 --AAELPGLVH----------------VETEAERVARFERDALPLLDQLY
MSMEG_4405|M.smegmatis_MC2_155 ---QHTAGTEP--------------APAANDTELSARFVNETLPYMSQLR
MLBr_01076|M.leprae_Br4923 IMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARVY
. : . : . . ::
Mflv_4689|M.gilvum_PYR-GCK GGALRMTRNPADAEDLLQETMVKAYSGFRSFREGTNLKAWLYRILTNTYI
Mvan_1778|M.vanbaalenii_PYR-1 GGALRMTRNPADAEDLLQETMVKAYSGFRSFREGTNLKAWLYRILTNTYI
TH_0665|M.thermoresistible__bu GGALRMTRNPADAEDLLQETMVKAYQGFRSFREGTNLKAWLYRILTNTYI
Mb3250c|M.bovis_AF2122/97 GGALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTYI
Rv3223c|M.tuberculosis_H37Rv GGALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTYI
MMAR_1334|M.marinum_M GGALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTYI
MUL_2545|M.ulcerans_Agy99 GGALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTYI
MAV_4171|M.avium_104 GGALRMTRNPADAEDLLQETMVKAYAGFRSFRAGTNLKAWLYRILTNTYI
MAB_3543c|M.abscessus_ATCC_199 GAALRMTRNPADAEDLVQETMVKAYAGFGTFKEGTNLKAWLYRILTNTYI
MSMEG_4405|M.smegmatis_MC2_155 SRARRLTRNPVDAEDLVQETMLRAYTGFGTFREGTNLRAWLLHIMTNTYI
MLBr_01076|M.leprae_Br4923 WLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTNLFL
* *:: * ***** ***:::.: .. .:: ** :..** :* ** ::
Mflv_4689|M.gilvum_PYR-GCK NSYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEVEALELLPDSEI
Mvan_1778|M.vanbaalenii_PYR-1 NSYRKKQRQPAEYPTEEITDWQLAANAEHSSTGLRSAEVEALELLPDNEI
TH_0665|M.thermoresistible__bu NNYRKRQRQPAVYPTEEFTDWQLASTAEHSSTGLRSAEVEALEALPDTEI
Mb3250c|M.bovis_AF2122/97 NSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTEI
Rv3223c|M.tuberculosis_H37Rv NSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTEI
MMAR_1334|M.marinum_M NSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTEI
MUL_2545|M.ulcerans_Agy99 NSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTEI
MAV_4171|M.avium_104 NSYRKKQRQPAEYPTEEITDWQLASNAEHSSTGLRSAEVEALESLPDSEI
MAB_3543c|M.abscessus_ATCC_199 NIYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEIEALDGLPDDEI
MSMEG_4405|M.smegmatis_MC2_155 SGLRRARRRPSEYLCDHTSDHQMAAQDRRS----QSAELDALDALPNIEL
MLBr_01076|M.leprae_Br4923 DMVRRRARIRMDALPDDYDRVPADEP---------NPEQIYHDSRLGPDL
. *: * :. ..* : . ::
Mflv_4689|M.gilvum_PYR-GCK KEALQALPEDFRMAVYYADVEGFPYKEIAEIMETPIGTVMSRLHRGRRQL
Mvan_1778|M.vanbaalenii_PYR-1 KEALQALPDEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQL
TH_0665|M.thermoresistible__bu KAALQELPEDFRIAVYLADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQL
Mb3250c|M.bovis_AF2122/97 KEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQL
Rv3223c|M.tuberculosis_H37Rv KEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQL
MMAR_1334|M.marinum_M KEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQL
MUL_2545|M.ulcerans_Agy99 KEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQL
MAV_4171|M.avium_104 KDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQL
MAB_3543c|M.abscessus_ATCC_199 KEALNKLPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQL
MSMEG_4405|M.smegmatis_MC2_155 AGALATLPEQFRLAIYYRDVVGLRYREIAEIMACSEGTIMSRLYRGRRRL
MLBr_01076|M.leprae_Br4923 QAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQAL
** ** :** *: *: *: *.**. : **: **::***: *
Mflv_4689|M.gilvum_PYR-GCK RELLAGVARDRGFIRGEQLEAPEEVTS
Mvan_1778|M.vanbaalenii_PYR-1 RELLAGVARDRGFIRGEQVDAPEEVTS
TH_0665|M.thermoresistible__bu RSLLADVARERGIIRDQQAGTPEEVSS
Mb3250c|M.bovis_AF2122/97 RGLLADVARDRGFARGEQ--AHEGVSS
Rv3223c|M.tuberculosis_H37Rv RGLLADVARDRGFARGEQ--AHEGVSS
MMAR_1334|M.marinum_M RTLLADVAKERGFVRGEQ--AHQEVSS
MUL_2545|M.ulcerans_Agy99 RTLLADVAKERGFVRGEQ--AHQEVSS
MAV_4171|M.avium_104 RGLLADVAKERGFNRGQQ--THEEVSS
MAB_3543c|M.abscessus_ATCC_199 RDLLSEVAKDRGFLRNNE--LAEGRA-
MSMEG_4405|M.smegmatis_MC2_155 RLLLAAGAT------------------
MLBr_01076|M.leprae_Br4923 RDYLLTAHPRDGATTDATHVKSA----
* *