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PDVVFPLDSTKKFTEQEKLGHNRWHPDIPPAVTVKKGDSFRVHCREWFDGAIHNDDSADDILNAPLTTVH VLSGPIAVEGAKPGDLLIVDILDVGPIPQEDSGPLAGQGWGYTGIFPTQNGGGFLTEQFPDAYKAIWDFS GQKATSRHIPGVEFTGIVHPGLMGTAPSAGLLAKWNAREAALIATDPERVPPLALPPEPQDAILGGLTGD AFTKAAAEAARTAPPRENGGNQDIKNLTKGSRVFYPVFVDGANLSVGDLHFSQGDGEITFCGAIEMGGFI DLRVDVIPGGMETYGVGENAIFMPGNTDPQYSEWLAFSGTSVTLDGEQRYLDSHLSYQRACLHAIDYLTK FGYSPEQAYLLLGAAPIEGRLSGVVDIPNACATVYIPTAIFDFPVTPTAAGPVKIDPGMGAPHSSFN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4367 | - | - | 100% (418) | formamidase |
| M. smegmatis MC2 155 | MSMEG_5335 | - | e-162 | 64.41% (413) | formamidase |
| M. smegmatis MC2 155 | MSMEG_0484 | - | 1e-51 | 35.79% (394) | formamidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2015 | - | 8e-15 | 29.39% (313) | acetamidase/formamidase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0587 | - | 0.0 | 88.67% (415) | acetamidase/formamidase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0852 | - | 1e-13 | 28.25% (315) | acetamidase/Formamidase family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0290 | - | 2e-15 | 26.85% (324) | acetamidase/formamidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2015|M.gilvum_PYR-GCK MTDPARRAAETLWTGIGRRDFLRAVAAVSAGAGVAGVSSACASGTPGPAS
TH_0852|M.thermoresistible__bu ---------------------------LSAGAGIATTLGACSS----RST
Mvan_0290|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4367|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0587|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2015|M.gilvum_PYR-GCK QSPSSAATDVAILQPGEGDPVGDHYLQSAPDEVLWGYVPNVHAAPVMRMS
TH_0852|M.thermoresistible__bu VRATGASTDFEILQPGQGEITGDHYLQSVPDQVLWGYVPTVHATPVMQMR
Mvan_0290|M.vanbaalenii_PYR-1 -------MIFPTLHPGEGHIGGEHYLPSHPDEVLWGWLPNAQTRPALSVA
MSMEG_4367|M.smegmatis_MC2_155 --------MPDVVFP----LDSTKKFTEQEKLGHNRWHPDIPPAVTVKKG
MAB_0587|M.abscessus_ATCC_1997 --------MPEVLFP----LDSNKKFTEQQIIGHNRWHPDIPPAAVVKPG
: * . : : . : * . .:
Mflv_2015|M.gilvum_PYR-GCK SGQTVTIDAVSHEGILEDQGRDPVGYFGGQGVSESEVLRDAIAIAAEY--
TH_0852|M.thermoresistible__bu SGQTVTIDTVSHEGILEDQGRNPVEYFGAEGVDENDVLEDVIAVAAEY--
Mvan_0290|M.vanbaalenii_PYR-1 SGDTVTIDTVSHEGILEDQGRDPVSYFAQFGVTN--VLKDVIDIASS---
MSMEG_4367|M.smegmatis_MC2_155 DSFRVHCREWFDGAIHNDDSADDILNAP---LTTVHVLSGPIAVEGAKPG
MAB_0587|M.abscessus_ATCC_1997 TSFRVHCREWFDGAIHNDDSADDIRDAP---LTTVHALSGPFSVEGAQPG
. * . .* :*:. : : : .* . : : .
Mflv_2015|M.gilvum_PYR-GCK DRTPRNFDKDGPHVVTGPVFVEGAQPGDVLKIEILQAIPRVPYGVVSSRH
TH_0852|M.thermoresistible__bu DRTPRDFDKDGPHVVTGPIFIEGAEPGDVLKIETLEATPRVPYGVVSSRH
Mvan_0290|M.vanbaalenii_PYR-1 --PLAHDDSCGPHIVTGPVRVANADPGDVLKIEVLDLAMRVPYGFVSSRH
MSMEG_4367|M.smegmatis_MC2_155 DLLIVDILDVGPIPQEDSGPLAGQGWGYTGIFPTQNGGGFLTEQFPDAYK
MAB_0587|M.abscessus_ATCC_1997 DLLIVDILDVGPIPQEDSGPLAGQGWGYTGIFPTVNGGGFLTEQFPDAYK
. . ** .. : . * . : : :. . .: :
Mflv_2015|M.gilvum_PYR-GCK GKGALAR-TADGAAPAGVGLSEVMPPVATDGRPDPDPTRYGNVSTFTAVE
TH_0852|M.thermoresistible__bu GKGALAL-TADGTPPAGITLDEVMPPAVTDGRSNPDPTRYGNLSTFTAVE
Mvan_0290|M.vanbaalenii_PYR-1 GYGALAG-EFP-EFPDSEPVREVDQIVSMGTICHFSWVEMLQGKPYGKIA
MSMEG_4367|M.smegmatis_MC2_155 AIWDFSGQKATSRHIPGVEFTGIVHPGLMGTAPSAGLLAKWNAREAALIA
MAB_0587|M.abscessus_ATCC_1997 AIWDFSGQTATSRHVPGVRFTGIVHPGLMGTAPSAELLARWNAREGALIA
. :: . . : . : :
Mflv_2015|M.gilvum_PYR-GCK DGHGVMRYGSAQVRFPLRPFMGMMG-VAFTQDREITAATANSIPPTVGGG
TH_0852|M.thermoresistible__bu DGHGVMSYGDARVRFPLAPFMGIMG-VAFAQDRDPTAPTANSVPPTIAGG
Mvan_0290|M.vanbaalenii_PYR-1 AGHGSGR----TVQFPVNPFLGIMG-VARA-----TEDPVPSVPPGTHGG
MSMEG_4367|M.smegmatis_MC2_155 TDPERVP----PLALPPEPQDAILGGLTGDAFTKAAAEAARTAPPRENGG
MAB_0587|M.abscessus_ATCC_1997 TDPNRVP----ALALPPEPRDAVLGALSGDSFDRAAAEAARTAPPRENGG
. : :* * .::* :: : .. : ** **
Mflv_2015|M.gilvum_PYR-GCK NIDIRLLGEGATFFLPVFAEGALFYVGDPHMAMGDGEVALT-AMEGSLRG
TH_0852|M.thermoresistible__bu NIDIRLLGEGSTLYLPVFAEGALFYVGDPHMAMGDGEVALT-AMEGSLRG
Mvan_0290|M.vanbaalenii_PYR-1 NIDIKHVVTGSTLYLPVQVEGANFFAGDPHFAQGNGEVALT-ALEASLRA
MSMEG_4367|M.smegmatis_MC2_155 NQDIKNLTKGSRVFYPVFVDGANLSVGDLHFSQGDGEITFCGAIEMGGFI
MAB_0587|M.abscessus_ATCC_1997 NQDIKNLTKGSRVFYPVFVPGGKLSVGDLHFSQGDGEITFCGAIEMGGFI
* **: : *: .: ** . *. : .** *:: *:**::: *:* .
Mflv_2015|M.gilvum_PYR-GCK TYRLTVCKPGSGDAPSVAYRYPFGETVD----AWVPIGLSDPDGSVGGQG
TH_0852|M.thermoresistible__bu TYRLTVCKPGSGDAPSVAYHYPFAETGD----AWVPIGLSDPDGSVGGQG
Mvan_0290|M.vanbaalenii_PYR-1 TVRLTVLKSGDAHSAIGALTNPVVETAT----HWIPTGMD----------
MSMEG_4367|M.smegmatis_MC2_155 DLRVDVIPGGMETYGVGENAIFMPGNTDPQYSEWLAFSGTSVTLDGEQRY
MAB_0587|M.abscessus_ATCC_1997 DLHVDVIKGGMDTYGVFENAIFMPGNTDPQYSQWLAFSGTSVTLDDEQRY
:: * * . . *:. .
Mflv_2015|M.gilvum_PYR-GCK SDLDVAMRRAVVNALDFLETD-----------------------QGMDRA
TH_0852|M.thermoresistible__bu TDLDVAMRRAVANALDFLEND-----------------------RGMDRA
Mvan_0290|M.vanbaalenii_PYR-1 ADLDEAMRIAVRNAIAFLNTR-----------------------FGVPRD
MSMEG_4367|M.smegmatis_MC2_155 LDSHLSYQRACLHAIDYLTKFGYSPEQAYLLLGAAPIEGRLSGVVDIPNA
MAB_0587|M.abscessus_ATCC_1997 LDSHLAYQRACLHAIDYLTKFGYSPEQAYLLLGAAPIEGRLSGVVDIPNS
* . : : * :*: :* . .: .
Mflv_2015|M.gilvum_PYR-GCK TAYAYLS-AAADFSVSQVVDRTVGVHGQIYKGHFGQS-
TH_0852|M.thermoresistible__bu TAYAYLS-AASHFAISQVVDRTVGVHGQIFKSHFAA--
Mvan_0290|M.vanbaalenii_PYR-1 VALAYLS-AAGDFEVSQVVDAVKGVHCMIRKADWAAWL
MSMEG_4367|M.smegmatis_MC2_155 CATVYIPTAIFDFPVTPTAAGPVKIDPGMGAPHSSFN-
MAB_0587|M.abscessus_ATCC_1997 CATVYIPTAIFDFPVTPTASGPVRIDPGPGAPRSVAR-
* .*:. * .* :: .. :.