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SVRIRRVTTTRAGGVSAPPYDSFNLGDHVGDDPAAVAANRQRLADAVSADAIVWMNQVHGDRVVTVDGPR ERAVNDTDALVTTVPGLALAVVTADCVPVLMADARAGVVAAAHAGRVGAQIGIVPRTLEAMLAAGAHVED ISVLLGPAVSGRNYEVPEAMAAEVEASLPGSRTTTSRGTPGLDLRAGIVRQLKGLGVAAIDVDPRCTVAD TTLFSHRRQAPTGRLACLVWMEQASR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4221 | - | - | 100% (237) | hypothetical protein MSMEG_4221 |
| M. smegmatis MC2 155 | MSMEG_3531 | - | 1e-05 | 33.93% (112) | hypothetical protein MSMEG_3531 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2173c | yfiH | 1e-100 | 77.45% (235) | hypothetical protein Mb2173c |
| M. gilvum PYR-GCK | Mflv_2992 | - | 1e-92 | 73.73% (236) | hypothetical protein Mflv_2992 |
| M. tuberculosis H37Rv | Rv2149c | yfiH | 1e-100 | 77.45% (235) | hypothetical protein Rv2149c |
| M. leprae Br4923 | MLBr_00918 | - | 2e-58 | 55.00% (240) | hypothetical protein MLBr_00918 |
| M. abscessus ATCC 19977 | MAB_2010 | - | 1e-92 | 72.29% (231) | hypothetical protein MAB_2010 |
| M. marinum M | MMAR_3189 | yfiH | 2e-98 | 77.45% (235) | membrane protein YfiH |
| M. avium 104 | MAV_2341 | - | 7e-98 | 77.45% (235) | hypothetical protein MAV_2341 |
| M. thermoresistible (build 8) | TH_2377 | yfiH | 6e-98 | 76.17% (235) | conserved hypothetical protein YfiH |
| M. ulcerans Agy99 | MUL_3497 | yfiH | 2e-98 | 77.45% (235) | membrane protein YfiH |
| M. vanbaalenii PYR-1 | Mvan_3519 | - | 3e-92 | 75.65% (230) | hypothetical protein Mvan_3519 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4221|M.smegmatis_MC2_155 ---------------------------MSVRIRRVTTTRAGGVSAPPYDS
MAB_2010|M.abscessus_ATCC_1997 ---------------------------MGFRVRRVTTTRRGGVSRAPFDS
Mflv_2992|M.gilvum_PYR-GCK ---------------------------MSFRVRRVTTTRAGGVSKPPYAT
Mvan_3519|M.vanbaalenii_PYR-1 ----------------------------------MTTTRAGGVSKPPFAT
TH_2377|M.thermoresistible__bu ---------------------------VTVRIRRVITTRAGGVSAPPYDS
Mb2173c|M.bovis_AF2122/97 MLASTRHIARG------------DTGNVSVRIRRVTTTRAGGVSAPPFDT
Rv2149c|M.tuberculosis_H37Rv MLASTRHIARG------------DTGNVSVRIRRVTTTRAGGVSAPPFDT
MMAR_3189|M.marinum_M MLARTRQTGRGRTAPQPGRQSNPDTGGVSVRIRRVTTTRKGGVSKPPFDS
MUL_3497|M.ulcerans_Agy99 MLARTRQTGRGRTAPQPGRQSNPDTGGVSVRIRRVTTTRKGGVSKPPFDS
MAV_2341|M.avium_104 ---------------------------MSVRIRRVTTTRAGGVSKPPFDS
MLBr_00918|M.leprae_Br4923 ------------------MGGFADTGQVSVRIRWVITMRAGGVLVSPFDF
: * * *** .*:
MSMEG_4221|M.smegmatis_MC2_155 FNLGDHVGDDP-AAVAANRQRLADAVSA--DAIVWMNQVHGDRVVTVDGP
MAB_2010|M.abscessus_ATCC_1997 FNLGDHVGDDP-GAVAANRSRLAAALGVPDDHLIWMQQVHGDHVHLVEGP
Mflv_2992|M.gilvum_PYR-GCK FNLGDHVGDDP-AAVAANRRRLAAATGLGDSGLAWMNQVHSTEVAVVDHG
Mvan_3519|M.vanbaalenii_PYR-1 FNLGDHVGDDP-EAVAANRRRLSAAVGLGDN-IVWMNQVHSANVAVVDHG
TH_2377|M.thermoresistible__bu FNLGDHVGDDP-AAVAANRARLAATIGLGEDRLVWMNQVHGDRIVVVDDT
Mb2173c|M.bovis_AF2122/97 FNLGDHVGDDP-AAVAANRARLAAAIGLPGNRVVWMNQVHGDRVELVDQP
Rv2149c|M.tuberculosis_H37Rv FNLGDHVGDDP-AAVAANRARLAAAIGLPGNRVVWMNQVHGDRVELVDQP
MMAR_3189|M.marinum_M FNLGDHVGDDP-ASVAANRARLAATIGMPTERVVWMNQVHGDRVEVVDAP
MUL_3497|M.ulcerans_Agy99 FNLGDHVGDDP-ASVAANRARLAATIGMPTERVVWMNQVHGDRVEVVDAP
MAV_2341|M.avium_104 FNLGDHVGDDP-AAVAANRARLAAALGLKPDRVVWMNQVHGDRVEVVHGP
MLBr_00918|M.leprae_Br4923 LDLGDHVGDDPDCGGHLSRAWLVAAIGLGVDRVVWMSQVHGDRVKVVHEP
::********* . .* * : . . : **.***. .: *.
MSMEG_4221|M.smegmatis_MC2_155 RERAVNDTDALVTTVPGLALAVVTADCVPVLMADARAGVVAAAHAG--RV
MAB_2010|M.abscessus_ATCC_1997 GTSTIPETDALVTTEPGIALAVLTADCVPVLFADAAAGVVAGAHAG--RV
Mflv_2992|M.gilvum_PYR-GCK G-DTVDDTDGLVTTRPGLALVVVTADCVPVLMADARAGVVAAVHAG--RV
Mvan_3519|M.vanbaalenii_PYR-1 G-ETVDATDGLVTTVPRLALAVVTADCVPVLMADARAGVVAAVHAG--RV
TH_2377|M.thermoresistible__bu VDHAVDDADGLVTTTPRLALVVVTADCVPVLMADARVGVVAAVHAG--RV
Mb2173c|M.bovis_AF2122/97 RNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAG--RA
Rv2149c|M.tuberculosis_H37Rv RNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAG--RA
MMAR_3189|M.marinum_M RDKAFDDTDALVTKVPGLALAVLTADCVPVLMADARAGVTAAVHAG--RV
MUL_3497|M.ulcerans_Agy99 RDNAFDDTDALVTKVPGLALAVLTADCVPVLMADARAGVTAAVHAG--RV
MAV_2341|M.avium_104 RDGAVDATDALVTGTARLALAVVTADCVPVLLADARAGVAAAVHAG--RV
MLBr_00918|M.leprae_Br4923 CDAVVDNTDALVTRTSQPALPVVTIHCVPVLLSDARPGVTAAVHVGEGRG
.. :*.*** . ** *:* .*****::** *:.*..*.* *
MSMEG_4221|M.smegmatis_MC2_155 GAQIGIVPRTLEAMLAAGAHVEDISVLLGPAVSGRNYEVPEAMAAEVEAS
MAB_2010|M.abscessus_ATCC_1997 GAKLGIVPRTIDAMVAAGAQVERISAFLGPAVSGRHYEVPADMAADVEQS
Mflv_2992|M.gilvum_PYR-GCK GAAGGIVARALETMVDAGADAGDVSVLLGPAVSGRNYEVPEAMAAEVEEA
Mvan_3519|M.vanbaalenii_PYR-1 GAAAGIVARALKTMTDAGARVEDVSVLLGPAVSGRNYEVPEAMAAEVEQA
TH_2377|M.thermoresistible__bu GAQRGVVVRAVQTMLDVGARVEDISALLGPAVSGRNYEVPAEMADEVERA
Mb2173c|M.bovis_AF2122/97 GAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAA
Rv2149c|M.tuberculosis_H37Rv GAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAA
MMAR_3189|M.marinum_M GAQRGIVARTVEAMQALGAQPGDISAFLGPAASGRNYEVPAAMADEVEAA
MUL_3497|M.ulcerans_Agy99 GAQRGIVARTVEAMQALGAQPGDISAFLGPAASGRNYEVPAAMADEVEAA
MAV_2341|M.avium_104 GAQRGVVVRTVEAMRALGAQPADMSALLGPAVSGANYEVPAAMADEVEAA
MLBr_00918|M.leprae_Br4923 SARCASPCDGYDAGPGCVRWRRDIAVLLGPAVSGRNYEVPVVIADGVEAA
.* . .. ::.:****.** :**** :* ** :
MSMEG_4221|M.smegmatis_MC2_155 LPGSRTTT--SRGTPGLDLRAGIVRQLKGLGVAAIDVDPRCTVADTTLFS
MAB_2010|M.abscessus_ATCC_1997 LPGSRTTT--SAGTPGLDLRAGIARQLSGLGVRAIDIDPRCTVEDPDLFS
Mflv_2992|M.gilvum_PYR-GCK LPGSRTTT--RRGTAGLDLRAGIAAQMRGLGVRAIDVDPRCTVEDRNLFS
Mvan_3519|M.vanbaalenii_PYR-1 LPGSRTTT--GRGTPGLDLRAGIATQLRALGVRSVDVDPRCTVDDPNLFS
TH_2377|M.thermoresistible__bu LPGSRTTT--AKGTPGLDLRAGIARQLTELGVTAIDIDPRCTVDDPDLFS
Mb2173c|M.bovis_AF2122/97 LPGSRTTT--AAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFS
Rv2149c|M.tuberculosis_H37Rv LPGSRTTT--AAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFS
MMAR_3189|M.marinum_M LPGSRTTS--AAGTAALDLRAGIARQLGDLGVKSIDVDPRCTVADPTLFS
MUL_3497|M.ulcerans_Agy99 LPGSRTTS--AAGTAALDLRAGIARQLGDLGVKSIDVDPRCTVADPTLFS
MAV_2341|M.avium_104 LPGSRTTT--AAGTPGLDLRAGIACQLRELGVTAIDIDPRCTVADPALFS
MLBr_00918|M.leprae_Br4923 SPDSCTTTRISAGTPGLDLRTGIACQFRDLGVMSIEDDPRRTVADRALFS
*.* **: **..:***:**. *: *** ::: *** ** * ***
MSMEG_4221|M.smegmatis_MC2_155 HRRQAPTGRLACLVWMEQASR
MAB_2010|M.abscessus_ATCC_1997 YRREPRTGRLASVIWLG----
Mflv_2992|M.gilvum_PYR-GCK HRRDNPTGRVASLIWLERR--
Mvan_3519|M.vanbaalenii_PYR-1 HRRDAPTGRLASLIWLEPAT-
TH_2377|M.thermoresistible__bu HRRGAPTGRLASLIWME----
Mb2173c|M.bovis_AF2122/97 HRRDAPTGRFASLVWME----
Rv2149c|M.tuberculosis_H37Rv HRRDAPTGRFASLVWME----
MMAR_3189|M.marinum_M HRRGAPTGRLASLVWME----
MUL_3497|M.ulcerans_Agy99 HRRGAPTGRLASLVWME----
MAV_2341|M.avium_104 HRRDAPTGRLASLIWME----
MLBr_00918|M.leprae_Br4923 HLQTVSTGRLASLVWME----
: : ***.*.::*: