For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLAAAIGLPGNRVV WMNQVHGDRVELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAGRAGAQRGV VVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAALPGSRTTTAAGTPGVDLRAGIACQLR DLGVESIDVDPRCTVADPTLFSHRRDAPTGRFASLVWME*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2149c | yfiH | - | 100% (250) | conserved hypothetical protein YfiH |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2173c | yfiH | 1e-140 | 100.00% (250) | hypothetical protein Mb2173c |
M. gilvum PYR-GCK | Mflv_2992 | - | 1e-93 | 73.19% (235) | hypothetical protein Mflv_2992 |
M. leprae Br4923 | MLBr_00918 | - | 4e-71 | 60.25% (244) | hypothetical protein MLBr_00918 |
M. abscessus ATCC 19977 | MAB_2010 | - | 8e-89 | 66.67% (231) | hypothetical protein MAB_2010 |
M. marinum M | MMAR_3189 | yfiH | 1e-111 | 77.86% (262) | membrane protein YfiH |
M. avium 104 | MAV_2341 | - | 1e-112 | 84.68% (235) | hypothetical protein MAV_2341 |
M. smegmatis MC2 155 | MSMEG_4221 | - | 1e-99 | 77.45% (235) | hypothetical protein MSMEG_4221 |
M. thermoresistible (build 8) | TH_2377 | yfiH | 1e-106 | 80.00% (235) | conserved hypothetical protein YfiH |
M. ulcerans Agy99 | MUL_3497 | yfiH | 1e-111 | 77.86% (262) | membrane protein YfiH |
M. vanbaalenii PYR-1 | Mvan_3519 | - | 1e-94 | 75.88% (228) | hypothetical protein Mvan_3519 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2992|M.gilvum_PYR-GCK ---------------------------MSFRVRRVTTTRAGGVSKPPYAT Mvan_3519|M.vanbaalenii_PYR-1 ----------------------------------MTTTRAGGVSKPPFAT MAB_2010|M.abscessus_ATCC_1997 ---------------------------MGFRVRRVTTTRRGGVSRAPFDS MSMEG_4221|M.smegmatis_MC2_155 ---------------------------MSVRIRRVTTTRAGGVSAPPYDS TH_2377|M.thermoresistible__bu ---------------------------VTVRIRRVITTRAGGVSAPPYDS Rv2149c|M.tuberculosis_H37Rv MLASTRHIARG------------DTGNVSVRIRRVTTTRAGGVSAPPFDT Mb2173c|M.bovis_AF2122/97 MLASTRHIARG------------DTGNVSVRIRRVTTTRAGGVSAPPFDT MMAR_3189|M.marinum_M MLARTRQTGRGRTAPQPGRQSNPDTGGVSVRIRRVTTTRKGGVSKPPFDS MUL_3497|M.ulcerans_Agy99 MLARTRQTGRGRTAPQPGRQSNPDTGGVSVRIRRVTTTRKGGVSKPPFDS MAV_2341|M.avium_104 ---------------------------MSVRIRRVTTTRAGGVSKPPFDS MLBr_00918|M.leprae_Br4923 ------------------MGGFADTGQVSVRIRWVITMRAGGVLVSPFDF : * * *** .*: Mflv_2992|M.gilvum_PYR-GCK FNLGDHVGDDP-AAVAANRRRLAAATGLGDSGLAWMNQVHSTEVAVVDHG Mvan_3519|M.vanbaalenii_PYR-1 FNLGDHVGDDP-EAVAANRRRLSAAVGLGDN-IVWMNQVHSANVAVVDHG MAB_2010|M.abscessus_ATCC_1997 FNLGDHVGDDP-GAVAANRSRLAAALGVPDDHLIWMQQVHGDHVHLVEGP MSMEG_4221|M.smegmatis_MC2_155 FNLGDHVGDDP-AAVAANRQRLADAVSA--DAIVWMNQVHGDRVVTVDGP TH_2377|M.thermoresistible__bu FNLGDHVGDDP-AAVAANRARLAATIGLGEDRLVWMNQVHGDRIVVVDDT Rv2149c|M.tuberculosis_H37Rv FNLGDHVGDDP-AAVAANRARLAAAIGLPGNRVVWMNQVHGDRVELVDQP Mb2173c|M.bovis_AF2122/97 FNLGDHVGDDP-AAVAANRARLAAAIGLPGNRVVWMNQVHGDRVELVDQP MMAR_3189|M.marinum_M FNLGDHVGDDP-ASVAANRARLAATIGMPTERVVWMNQVHGDRVEVVDAP MUL_3497|M.ulcerans_Agy99 FNLGDHVGDDP-ASVAANRARLAATIGMPTERVVWMNQVHGDRVEVVDAP MAV_2341|M.avium_104 FNLGDHVGDDP-AAVAANRARLAAALGLKPDRVVWMNQVHGDRVEVVHGP MLBr_00918|M.leprae_Br4923 LDLGDHVGDDPDCGGHLSRAWLVAAIGLGVDRVVWMSQVHGDRVKVVHEP ::********* . .* * : . . : **.***. .: *. Mflv_2992|M.gilvum_PYR-GCK G-DTVDDTDGLVTTRPGLALVVVTADCVPVLMADARAGVVAAVHAG--RV Mvan_3519|M.vanbaalenii_PYR-1 G-ETVDATDGLVTTVPRLALAVVTADCVPVLMADARAGVVAAVHAG--RV MAB_2010|M.abscessus_ATCC_1997 GTSTIPETDALVTTEPGIALAVLTADCVPVLFADAAAGVVAGAHAG--RV MSMEG_4221|M.smegmatis_MC2_155 RERAVNDTDALVTTVPGLALAVVTADCVPVLMADARAGVVAAAHAG--RV TH_2377|M.thermoresistible__bu VDHAVDDADGLVTTTPRLALVVVTADCVPVLMADARVGVVAAVHAG--RV Rv2149c|M.tuberculosis_H37Rv RNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAG--RA Mb2173c|M.bovis_AF2122/97 RNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAG--RA MMAR_3189|M.marinum_M RDKAFDDTDALVTKVPGLALAVLTADCVPVLMADARAGVTAAVHAG--RV MUL_3497|M.ulcerans_Agy99 RDNAFDDTDALVTKVPGLALAVLTADCVPVLMADARAGVTAAVHAG--RV MAV_2341|M.avium_104 RDGAVDATDALVTGTARLALAVVTADCVPVLLADARAGVAAAVHAG--RV MLBr_00918|M.leprae_Br4923 CDAVVDNTDALVTRTSQPALPVVTIHCVPVLLSDARPGVTAAVHVGEGRG .. :*.*** . ** *:* .*****::** *:.*..*.* * Mflv_2992|M.gilvum_PYR-GCK GAAGGIVARALETMVDAGADAGDVSVLLGPAVSGRNYEVPEAMAAEVEEA Mvan_3519|M.vanbaalenii_PYR-1 GAAAGIVARALKTMTDAGARVEDVSVLLGPAVSGRNYEVPEAMAAEVEQA MAB_2010|M.abscessus_ATCC_1997 GAKLGIVPRTIDAMVAAGAQVERISAFLGPAVSGRHYEVPADMAADVEQS MSMEG_4221|M.smegmatis_MC2_155 GAQIGIVPRTLEAMLAAGAHVEDISVLLGPAVSGRNYEVPEAMAAEVEAS TH_2377|M.thermoresistible__bu GAQRGVVVRAVQTMLDVGARVEDISALLGPAVSGRNYEVPAEMADEVERA Rv2149c|M.tuberculosis_H37Rv GAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAA Mb2173c|M.bovis_AF2122/97 GAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAA MMAR_3189|M.marinum_M GAQRGIVARTVEAMQALGAQPGDISAFLGPAASGRNYEVPAAMADEVEAA MUL_3497|M.ulcerans_Agy99 GAQRGIVARTVEAMQALGAQPGDISAFLGPAASGRNYEVPAAMADEVEAA MAV_2341|M.avium_104 GAQRGVVVRTVEAMRALGAQPADMSALLGPAVSGANYEVPAAMADEVEAA MLBr_00918|M.leprae_Br4923 SARCASPCDGYDAGPGCVRWRRDIAVLLGPAVSGRNYEVPVVIADGVEAA .* . .. ::.:****.** :**** :* ** : Mflv_2992|M.gilvum_PYR-GCK LPGSRTTT--RRGTAGLDLRAGIAAQMRGLGVRAIDVDPRCTVEDRNLFS Mvan_3519|M.vanbaalenii_PYR-1 LPGSRTTT--GRGTPGLDLRAGIATQLRALGVRSVDVDPRCTVDDPNLFS MAB_2010|M.abscessus_ATCC_1997 LPGSRTTT--SAGTPGLDLRAGIARQLSGLGVRAIDIDPRCTVEDPDLFS MSMEG_4221|M.smegmatis_MC2_155 LPGSRTTT--SRGTPGLDLRAGIVRQLKGLGVAAIDVDPRCTVADTTLFS TH_2377|M.thermoresistible__bu LPGSRTTT--AKGTPGLDLRAGIARQLTELGVTAIDIDPRCTVDDPDLFS Rv2149c|M.tuberculosis_H37Rv LPGSRTTT--AAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFS Mb2173c|M.bovis_AF2122/97 LPGSRTTT--AAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFS MMAR_3189|M.marinum_M LPGSRTTS--AAGTAALDLRAGIARQLGDLGVKSIDVDPRCTVADPTLFS MUL_3497|M.ulcerans_Agy99 LPGSRTTS--AAGTAALDLRAGIARQLGDLGVKSIDVDPRCTVADPTLFS MAV_2341|M.avium_104 LPGSRTTT--AAGTPGLDLRAGIACQLRELGVTAIDIDPRCTVADPALFS MLBr_00918|M.leprae_Br4923 SPDSCTTTRISAGTPGLDLRTGIACQFRDLGVMSIEDDPRRTVADRALFS *.* **: **..:***:**. *: *** ::: *** ** * *** Mflv_2992|M.gilvum_PYR-GCK HRRDNPTGRVASLIWLERR-- Mvan_3519|M.vanbaalenii_PYR-1 HRRDAPTGRLASLIWLEPAT- MAB_2010|M.abscessus_ATCC_1997 YRREPRTGRLASVIWLG---- MSMEG_4221|M.smegmatis_MC2_155 HRRQAPTGRLACLVWMEQASR TH_2377|M.thermoresistible__bu HRRGAPTGRLASLIWME---- Rv2149c|M.tuberculosis_H37Rv HRRDAPTGRFASLVWME---- Mb2173c|M.bovis_AF2122/97 HRRDAPTGRFASLVWME---- MMAR_3189|M.marinum_M HRRGAPTGRLASLVWME---- MUL_3497|M.ulcerans_Agy99 HRRGAPTGRLASLVWME---- MAV_2341|M.avium_104 HRRDAPTGRLASLIWME---- MLBr_00918|M.leprae_Br4923 HLQTVSTGRLASLVWME---- : : ***.*.::*: