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M. tuberculosis H37Rv Rv2149c (yfiH)

annotation: conserved hypothetical protein YfiH
coordinates: 2407622 - 2408374
length: 250

LASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLAAAIGLPGNRVV
WMNQVHGDRVELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAGRAGAQRGV
VVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAALPGSRTTTAAGTPGVDLRAGIACQLR
DLGVESIDVDPRCTVADPTLFSHRRDAPTGRFASLVWME*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2149cyfiH-100% (250)conserved hypothetical protein YfiH

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2173cyfiH1e-140100.00% (250) hypothetical protein Mb2173c
M. gilvum PYR-GCKMflv_2992-1e-9373.19% (235) hypothetical protein Mflv_2992
M. leprae Br4923MLBr_00918-4e-7160.25% (244) hypothetical protein MLBr_00918
M. abscessus ATCC 19977MAB_2010-8e-8966.67% (231) hypothetical protein MAB_2010
M. marinum MMMAR_3189yfiH1e-11177.86% (262) membrane protein YfiH
M. avium 104MAV_2341-1e-11284.68% (235) hypothetical protein MAV_2341
M. smegmatis MC2 155MSMEG_4221-1e-9977.45% (235) hypothetical protein MSMEG_4221
M. thermoresistible (build 8)TH_2377yfiH1e-10680.00% (235) conserved hypothetical protein YfiH
M. ulcerans Agy99MUL_3497yfiH1e-11177.86% (262) membrane protein YfiH
M. vanbaalenii PYR-1Mvan_3519-1e-9475.88% (228) hypothetical protein Mvan_3519

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2992|M.gilvum_PYR-GCK          ---------------------------MSFRVRRVTTTRAGGVSKPPYAT
Mvan_3519|M.vanbaalenii_PYR-1       ----------------------------------MTTTRAGGVSKPPFAT
MAB_2010|M.abscessus_ATCC_1997      ---------------------------MGFRVRRVTTTRRGGVSRAPFDS
MSMEG_4221|M.smegmatis_MC2_155      ---------------------------MSVRIRRVTTTRAGGVSAPPYDS
TH_2377|M.thermoresistible__bu      ---------------------------VTVRIRRVITTRAGGVSAPPYDS
Rv2149c|M.tuberculosis_H37Rv        MLASTRHIARG------------DTGNVSVRIRRVTTTRAGGVSAPPFDT
Mb2173c|M.bovis_AF2122/97           MLASTRHIARG------------DTGNVSVRIRRVTTTRAGGVSAPPFDT
MMAR_3189|M.marinum_M               MLARTRQTGRGRTAPQPGRQSNPDTGGVSVRIRRVTTTRKGGVSKPPFDS
MUL_3497|M.ulcerans_Agy99           MLARTRQTGRGRTAPQPGRQSNPDTGGVSVRIRRVTTTRKGGVSKPPFDS
MAV_2341|M.avium_104                ---------------------------MSVRIRRVTTTRAGGVSKPPFDS
MLBr_00918|M.leprae_Br4923          ------------------MGGFADTGQVSVRIRWVITMRAGGVLVSPFDF
                                                                      : * * ***  .*:  

Mflv_2992|M.gilvum_PYR-GCK          FNLGDHVGDDP-AAVAANRRRLAAATGLGDSGLAWMNQVHSTEVAVVDHG
Mvan_3519|M.vanbaalenii_PYR-1       FNLGDHVGDDP-EAVAANRRRLSAAVGLGDN-IVWMNQVHSANVAVVDHG
MAB_2010|M.abscessus_ATCC_1997      FNLGDHVGDDP-GAVAANRSRLAAALGVPDDHLIWMQQVHGDHVHLVEGP
MSMEG_4221|M.smegmatis_MC2_155      FNLGDHVGDDP-AAVAANRQRLADAVSA--DAIVWMNQVHGDRVVTVDGP
TH_2377|M.thermoresistible__bu      FNLGDHVGDDP-AAVAANRARLAATIGLGEDRLVWMNQVHGDRIVVVDDT
Rv2149c|M.tuberculosis_H37Rv        FNLGDHVGDDP-AAVAANRARLAAAIGLPGNRVVWMNQVHGDRVELVDQP
Mb2173c|M.bovis_AF2122/97           FNLGDHVGDDP-AAVAANRARLAAAIGLPGNRVVWMNQVHGDRVELVDQP
MMAR_3189|M.marinum_M               FNLGDHVGDDP-ASVAANRARLAATIGMPTERVVWMNQVHGDRVEVVDAP
MUL_3497|M.ulcerans_Agy99           FNLGDHVGDDP-ASVAANRARLAATIGMPTERVVWMNQVHGDRVEVVDAP
MAV_2341|M.avium_104                FNLGDHVGDDP-AAVAANRARLAAALGLKPDRVVWMNQVHGDRVEVVHGP
MLBr_00918|M.leprae_Br4923          LDLGDHVGDDPDCGGHLSRAWLVAAIGLGVDRVVWMSQVHGDRVKVVHEP
                                    ::*********  .   .*  *  : .   . : **.***. .:  *.  

Mflv_2992|M.gilvum_PYR-GCK          G-DTVDDTDGLVTTRPGLALVVVTADCVPVLMADARAGVVAAVHAG--RV
Mvan_3519|M.vanbaalenii_PYR-1       G-ETVDATDGLVTTVPRLALAVVTADCVPVLMADARAGVVAAVHAG--RV
MAB_2010|M.abscessus_ATCC_1997      GTSTIPETDALVTTEPGIALAVLTADCVPVLFADAAAGVVAGAHAG--RV
MSMEG_4221|M.smegmatis_MC2_155      RERAVNDTDALVTTVPGLALAVVTADCVPVLMADARAGVVAAAHAG--RV
TH_2377|M.thermoresistible__bu      VDHAVDDADGLVTTTPRLALVVVTADCVPVLMADARVGVVAAVHAG--RV
Rv2149c|M.tuberculosis_H37Rv        RNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAG--RA
Mb2173c|M.bovis_AF2122/97           RNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAG--RA
MMAR_3189|M.marinum_M               RDKAFDDTDALVTKVPGLALAVLTADCVPVLMADARAGVTAAVHAG--RV
MUL_3497|M.ulcerans_Agy99           RDNAFDDTDALVTKVPGLALAVLTADCVPVLMADARAGVTAAVHAG--RV
MAV_2341|M.avium_104                RDGAVDATDALVTGTARLALAVVTADCVPVLLADARAGVAAAVHAG--RV
MLBr_00918|M.leprae_Br4923          CDAVVDNTDALVTRTSQPALPVVTIHCVPVLLSDARPGVTAAVHVGEGRG
                                       ..  :*.***  .  ** *:* .*****::**  *:.*..*.*  * 

Mflv_2992|M.gilvum_PYR-GCK          GAAGGIVARALETMVDAGADAGDVSVLLGPAVSGRNYEVPEAMAAEVEEA
Mvan_3519|M.vanbaalenii_PYR-1       GAAAGIVARALKTMTDAGARVEDVSVLLGPAVSGRNYEVPEAMAAEVEQA
MAB_2010|M.abscessus_ATCC_1997      GAKLGIVPRTIDAMVAAGAQVERISAFLGPAVSGRHYEVPADMAADVEQS
MSMEG_4221|M.smegmatis_MC2_155      GAQIGIVPRTLEAMLAAGAHVEDISVLLGPAVSGRNYEVPEAMAAEVEAS
TH_2377|M.thermoresistible__bu      GAQRGVVVRAVQTMLDVGARVEDISALLGPAVSGRNYEVPAEMADEVERA
Rv2149c|M.tuberculosis_H37Rv        GAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAA
Mb2173c|M.bovis_AF2122/97           GAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAA
MMAR_3189|M.marinum_M               GAQRGIVARTVEAMQALGAQPGDISAFLGPAASGRNYEVPAAMADEVEAA
MUL_3497|M.ulcerans_Agy99           GAQRGIVARTVEAMQALGAQPGDISAFLGPAASGRNYEVPAAMADEVEAA
MAV_2341|M.avium_104                GAQRGVVVRTVEAMRALGAQPADMSALLGPAVSGANYEVPAAMADEVEAA
MLBr_00918|M.leprae_Br4923          SARCASPCDGYDAGPGCVRWRRDIAVLLGPAVSGRNYEVPVVIADGVEAA
                                    .*  .      ..          ::.:****.** :****  :*  ** :

Mflv_2992|M.gilvum_PYR-GCK          LPGSRTTT--RRGTAGLDLRAGIAAQMRGLGVRAIDVDPRCTVEDRNLFS
Mvan_3519|M.vanbaalenii_PYR-1       LPGSRTTT--GRGTPGLDLRAGIATQLRALGVRSVDVDPRCTVDDPNLFS
MAB_2010|M.abscessus_ATCC_1997      LPGSRTTT--SAGTPGLDLRAGIARQLSGLGVRAIDIDPRCTVEDPDLFS
MSMEG_4221|M.smegmatis_MC2_155      LPGSRTTT--SRGTPGLDLRAGIVRQLKGLGVAAIDVDPRCTVADTTLFS
TH_2377|M.thermoresistible__bu      LPGSRTTT--AKGTPGLDLRAGIARQLTELGVTAIDIDPRCTVDDPDLFS
Rv2149c|M.tuberculosis_H37Rv        LPGSRTTT--AAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFS
Mb2173c|M.bovis_AF2122/97           LPGSRTTT--AAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFS
MMAR_3189|M.marinum_M               LPGSRTTS--AAGTAALDLRAGIARQLGDLGVKSIDVDPRCTVADPTLFS
MUL_3497|M.ulcerans_Agy99           LPGSRTTS--AAGTAALDLRAGIARQLGDLGVKSIDVDPRCTVADPTLFS
MAV_2341|M.avium_104                LPGSRTTT--AAGTPGLDLRAGIACQLRELGVTAIDIDPRCTVADPALFS
MLBr_00918|M.leprae_Br4923          SPDSCTTTRISAGTPGLDLRTGIACQFRDLGVMSIEDDPRRTVADRALFS
                                     *.* **:    **..:***:**. *:  *** ::: *** ** *  ***

Mflv_2992|M.gilvum_PYR-GCK          HRRDNPTGRVASLIWLERR--
Mvan_3519|M.vanbaalenii_PYR-1       HRRDAPTGRLASLIWLEPAT-
MAB_2010|M.abscessus_ATCC_1997      YRREPRTGRLASVIWLG----
MSMEG_4221|M.smegmatis_MC2_155      HRRQAPTGRLACLVWMEQASR
TH_2377|M.thermoresistible__bu      HRRGAPTGRLASLIWME----
Rv2149c|M.tuberculosis_H37Rv        HRRDAPTGRFASLVWME----
Mb2173c|M.bovis_AF2122/97           HRRDAPTGRFASLVWME----
MMAR_3189|M.marinum_M               HRRGAPTGRLASLVWME----
MUL_3497|M.ulcerans_Agy99           HRRGAPTGRLASLVWME----
MAV_2341|M.avium_104                HRRDAPTGRLASLIWME----
MLBr_00918|M.leprae_Br4923          HLQTVSTGRLASLVWME----
                                    : :   ***.*.::*: