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SVVGVESTGDIVTLTINRPEAFNALDGEVIGALAAEVGAAAAVGLRAVIITGAGEKAFSAGADLKELAGM GPDQAQETITRGQQAFRAIEQAPIPVIAAVNGLALGGGFELILACTFPVLSTKASMGLPESGLGLIPGYG GTQRLPRVLGEKVAAHLMLTGTRLDADRAYTLGLTPLPPVDPTELLATAKAMADKIAAQGPLAVRAILRA LDVSRDAPVDSGLAVETGLAALAVSGAESGEGVAAFLERRPAKFANPEGPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4119 | - | - | 100% (262) | 3-hydroxybutyryl-CoA dehydratase |
| M. smegmatis MC2 155 | MSMEG_5277 | - | 1e-34 | 38.85% (260) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_6777 | - | 4e-33 | 36.44% (247) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 1e-32 | 36.33% (256) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2036 | - | 2e-35 | 38.52% (257) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 1e-32 | 36.33% (256) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-31 | 36.59% (246) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_1185c | - | 4e-34 | 38.00% (250) | enoyl-CoA hydratase |
| M. marinum M | MMAR_4396 | echA8 | 3e-36 | 38.76% (258) | enoyl-CoA hydratase EchA8 |
| M. avium 104 | MAV_4951 | - | 8e-35 | 39.84% (251) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_4102 | - | 9e-35 | 40.00% (250) | PUTATIVE short chain enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 2e-36 | 38.76% (258) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4681 | - | 5e-36 | 39.30% (257) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1099c|M.bovis_AF2122/97 ---MTYET----------ILVERDQRVGIITLNRPQALNALNSQVMNEVT
Rv1070c|M.tuberculosis_H37Rv ---MTYET----------ILVERDQRVGIITLNRPQALNALNSQVMNEVT
MMAR_4396|M.marinum_M ---MSYET----------ILVERDQRVGIITLNRPQALNALNSQVMNEVT
MUL_0210|M.ulcerans_Agy99 ---MSYET----------ILVERDQRVGIITLNRPQALNALNSQVMNEVT
MLBr_02402|M.leprae_Br4923 ---MKYDT----------ILVDGYQRVGIITLNRPQALNALNSQMMNEIT
TH_4102|M.thermoresistible__bu MSAKNYET----------ILVTREDRVGIITLNRPKALNALNSQVMTEVT
Mflv_2036|M.gilvum_PYR-GCK ---MTFET----------ILVDRDDRVATITLNRPKALNALNTQVMNEVT
Mvan_4681|M.vanbaalenii_PYR-1 MGSQNFET----------IIVERDDRVATITLNRPKALNALNSQVMDEVT
MAB_1185c|M.abscessus_ATCC_199 MTSHNFET----------ILTERIDRVAVITLNRPKALNALNSQVMNEVT
MSMEG_4119|M.smegmatis_MC2_155 ---MSVVG------------VESTGDIVTLTINRPEAFNALDGEVIGALA
MAV_4951|M.avium_104 ---MRHVSTGNEEAGEPEVLVEQRDRILIITINRPKAKNAVNAAVANGLA
. : :*:***:* **:: : ::
Mb1099c|M.bovis_AF2122/97 SAATELDDDPDIGAIIITGSAK-AFAAGADIKEMADL--TFADAFTADFF
Rv1070c|M.tuberculosis_H37Rv SAATELDDDPDIGAIIITGSAK-AFAAGADIKEMADL--TFADAFTADFF
MMAR_4396|M.marinum_M SAAAELDNDPGIGAIIITGSAK-AFAAGADIKEMADL--TFSEAFDADFF
MUL_0210|M.ulcerans_Agy99 SAAAELDNDPGIGAIIITGSAK-AFAAGADIKEMADL--TFSEAFDADFF
MLBr_02402|M.leprae_Br4923 NAAKELDIDPDVGAILITGSPK-VFAAGADIKEMASL--TFTDAFDADFF
TH_4102|M.thermoresistible__bu DAAAEFDSDPGIGAIIVTGNEK-AFAAGADIKEMADL--EFADVFAADFF
Mflv_2036|M.gilvum_PYR-GCK TAAAELDAEPGVGAIIVTGSER-AFAAGADIKEMASL--SFADVFSSDFF
Mvan_4681|M.vanbaalenii_PYR-1 TAAAELDADAGVGAIILTGSEK-AFAAGADIKEMAGL--SFADVFSSDFF
MAB_1185c|M.abscessus_ATCC_199 TAAAEFDADHGIGAIIITGSEK-AFAAGADIKEMSEQ--SFSDMFGSDFF
MSMEG_4119|M.smegmatis_MC2_155 AEVG-AAAAVGLRAVIITGAGEKAFSAGADLKELAGMGPDQAQETITRGQ
MAV_4951|M.avium_104 AAVDRLDSEPGLSVGVLTGAGG-SFCAGMDLKAFA-----RGELPIVEGR
. .: . ::** *.** *:* :: :
Mb1099c|M.bovis_AF2122/97 ATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKL
Rv1070c|M.tuberculosis_H37Rv ATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKL
MMAR_4396|M.marinum_M AAWGKLAAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKL
MUL_0210|M.ulcerans_Agy99 AAWGKLAAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKL
MLBr_02402|M.leprae_Br4923 SAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKL
TH_4102|M.thermoresistible__bu APWSKFAATRTPTIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKL
Mflv_2036|M.gilvum_PYR-GCK AAWGKFAATRTPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKL
Mvan_4681|M.vanbaalenii_PYR-1 AGWGKFAATRTPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKL
MAB_1185c|M.abscessus_ATCC_199 SAWGKLGAVRTPTIAAVSGYALGGGCELAMMCDVIIAAENATFGQPEIKL
MSMEG_4119|M.smegmatis_MC2_155 QAFRAIEQAPIPVIAAVNGLALGGGFELILACTFPVLSTKASMGLPESGL
MAV_4951|M.avium_104 GMGFTERPPAKPLIAAVEGYALAGGTELALATDLIVASKDAAFGIPEVKR
* **** * **.** *: : . : : * :* **
Mb1099c|M.bovis_AF2122/97 GVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRV-VPAD
Rv1070c|M.tuberculosis_H37Rv GVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRV-VPAD
MMAR_4396|M.marinum_M GVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRV-VPAD
MUL_0210|M.ulcerans_Agy99 GVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRV-VPAD
MLBr_02402|M.leprae_Br4923 GVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRV-VLAD
TH_4102|M.thermoresistible__bu GVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAEEAERSGLVSRV-VPAD
Mflv_2036|M.gilvum_PYR-GCK GVLPGMGGSQRLTRAIGKAKAMDLILTGRNMDAEEAERAGLVSRV-VPAD
Mvan_4681|M.vanbaalenii_PYR-1 GVLPGMGGSQRLTRAIGKAKAMDLILTGRNMGAEEAERAGLVSRV-VPAD
MAB_1185c|M.abscessus_ATCC_199 GVLPGMGGSQRLTRAIGKAKAMDMILTGRNMDAAEAERSGLVSRV-VATE
MSMEG_4119|M.smegmatis_MC2_155 GLIPGYGGTQRLPRVLGEKVAAHLMLTGTRLDADRAYTLGLTPLPPVDPT
MAV_4951|M.avium_104 GLVAGGGGLLRLPQRIPSAIAMELALTGDNLSAERAHALGMVNVL-AEPG
*::.* ** **.: : . * .: *** :.* .* *:. . .
Mb1099c|M.bovis_AF2122/97 DLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSA
Rv1070c|M.tuberculosis_H37Rv DLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSA
MMAR_4396|M.marinum_M DLLTEAKAVATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSA
MUL_0210|M.ulcerans_Agy99 DLLTEAKAVATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSA
MLBr_02402|M.leprae_Br4923 DLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHST
TH_4102|M.thermoresistible__bu KLLDEAKETAATIAAMSLSAARMAKEAVNRAFETSLAEGLLFERRVFHSA
Mflv_2036|M.gilvum_PYR-GCK SLLSEAKAVAQTIAGMSLSASRMAKEAVDRAFETTLSEGLLYERRLFHSA
Mvan_4681|M.vanbaalenii_PYR-1 TLLEEARSVAKTIAGMSLSASRMAKEAVDRAFETTLTEGLLYERRLFHSA
MAB_1185c|M.abscessus_ATCC_199 SLLDEAKAVAKTISEMSLSASMMAKEAVNRAFESSLAEGLLFERRIFHSA
MSMEG_4119|M.smegmatis_MC2_155 ELLATAKAMADKIAAQGPLAVRAILRALDVSRDAPVDSGLAVETGLAALA
MAV_4951|M.avium_104 SALDEAIALAEKIAANGPLAVAATKRIIVESRGWSPETMFAEQNKLLAPV
* * * .*: . * . : : . : : : .
Mb1099c|M.bovis_AF2122/97 FATEDQSEGMAAFIEKRAPQFTHR----
Rv1070c|M.tuberculosis_H37Rv FATEDQSEGMAAFIEKRAPQFTHR----
MMAR_4396|M.marinum_M FATADQSEGMAAFIEKRPPNFTHR----
MUL_0210|M.ulcerans_Agy99 FATADQSEGMAAFIEKRPPNFTHR----
MLBr_02402|M.leprae_Br4923 FVTDDQSEGMAAFIEKRAPQFTHR----
TH_4102|M.thermoresistible__bu FATADQSEGMAAFTEKRPPKFTHR----
Mflv_2036|M.gilvum_PYR-GCK FATDDQTEGMNAFSEKRSPNFTHR----
Mvan_4681|M.vanbaalenii_PYR-1 FATDDQTEGMNAFTEKRSPNFTHR----
MAB_1185c|M.abscessus_ATCC_199 FGTADQSEGMAAFVEKRPANFIHR----
MSMEG_4119|M.smegmatis_MC2_155 VSGAESGEGVAAFLERRPAKFANPEGPL
MAV_4951|M.avium_104 FSSNDAKEGAIAFAEKRPPKWTGT----
. : ** ** *:*..::