For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_4077 (-)

annotation: enoyl-CoA hydratase
coordinates: 4150741 - 4151499
length: 252

VNGEPGSVEVARDGDVAVVTLRREHKLNALSMHMETQLLTALRTQEVRTSRAVVVTGGNTVFSAGADVNE
IRTLTPDAILAYYRNSGSVYEVFAELPQPTVVAVAGYCLGGGLELSLAGDIRIADETAVFGFPEIQIGIL
PSSGGVTRAARTLGYGRATDLILRGRRFGAHQALQWGLLTEVTNKGSHIRTALTIAHEIAEHDPLVVSVT
KQVIHASPDASQAASLLLERLAYAVLNRTTPAAHAHDEVKQP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4077--100% (252)enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_6777-2e-3137.90% (219) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_5277-1e-3035.56% (225) enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1099cechA85e-3134.96% (226) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_2036-3e-3234.40% (250) enoyl-CoA hydratase
M. tuberculosis H37RvRv1070cechA86e-3134.96% (226) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-2e-3136.41% (217) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_1185c-2e-2934.72% (216) enoyl-CoA hydratase
M. marinum MMMAR_4396echA81e-3034.22% (225) enoyl-CoA hydratase EchA8
M. avium 104MAV_1195-1e-3034.67% (225) enoyl-CoA hydratase
M. thermoresistible (build 8)TH_4102-7e-3135.09% (228) PUTATIVE short chain enoyl-CoA hydratase
M. ulcerans Agy99MUL_0210echA89e-3134.22% (225) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_4681-9e-3236.00% (225) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4396|M.marinum_M               ------MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELD
MUL_0210|M.ulcerans_Agy99           ------MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELD
MLBr_02402|M.leprae_Br4923          ------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELD
Mb1099c|M.bovis_AF2122/97           ------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELD
Rv1070c|M.tuberculosis_H37Rv        ------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELD
MAV_1195|M.avium_104                MTDSTDRTFETILVEREERVGIITLNRPKALNALNTQVMNEVTTAATDFD
TH_4102|M.thermoresistible__bu      ---MSAKNYETILVTREDRVGIITLNRPKALNALNSQVMTEVTDAAAEFD
Mflv_2036|M.gilvum_PYR-GCK          ------MTFETILVDRDDRVATITLNRPKALNALNTQVMNEVTTAAAELD
Mvan_4681|M.vanbaalenii_PYR-1       ---MGSQNFETIIVERDDRVATITLNRPKALNALNSQVMDEVTTAAAELD
MAB_1185c|M.abscessus_ATCC_199      ---MTSHNFETILTERIDRVAVITLNRPKALNALNSQVMNEVTTAAAEFD
MSMEG_4077|M.smegmatis_MC2_155      ----MNGEPGSVEVARDGDVAVVTLRREHKLNALSMHMETQLLTALRTQE
                                              :: .     *. :**.* : ****. ::  ::  *    :

MMAR_4396|M.marinum_M               NDPGIGAIIITGSAKAFAAGADIKEMADLT--FSEAFDADFFAAWGKLAA
MUL_0210|M.ulcerans_Agy99           NDPGIGAIIITGSAKAFAAGADIKEMADLT--FSEAFDADFFAAWGKLAA
MLBr_02402|M.leprae_Br4923          IDPDVGAILITGSPKVFAAGADIKEMASLT--FTDAFDADFFSAWGKLAA
Mb1099c|M.bovis_AF2122/97           DDPDIGAIIITGSAKAFAAGADIKEMADLT--FADAFTADFFATWGKLAA
Rv1070c|M.tuberculosis_H37Rv        DDPDIGAIIITGSAKAFAAGADIKEMADLT--FADAFTADFFATWGKLAA
MAV_1195|M.avium_104                ADPGIGAIIITGSAKAFAAGADIKEMAELT--FADAYGADFFAPWGKLAA
TH_4102|M.thermoresistible__bu      SDPGIGAIIVTGNEKAFAAGADIKEMADLE--FADVFAADFFAPWSKFAA
Mflv_2036|M.gilvum_PYR-GCK          AEPGVGAIIVTGSERAFAAGADIKEMASLS--FADVFSSDFFAAWGKFAA
Mvan_4681|M.vanbaalenii_PYR-1       ADAGVGAIILTGSEKAFAAGADIKEMAGLS--FADVFSSDFFAGWGKFAA
MAB_1185c|M.abscessus_ATCC_199      ADHGIGAIIITGSEKAFAAGADIKEMSEQS--FSDMFGSDFFSAWGKLGA
MSMEG_4077|M.smegmatis_MC2_155      VRTSR-AVVVTGGNTVFSAGADVNEIRTLTPDAILAYYRNSGSVYEVFAE
                                       .  *:::**.  .*:****::*:          :  :  : :  :. 

MMAR_4396|M.marinum_M               VRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPGMGG
MUL_0210|M.ulcerans_Agy99           VRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPGMGG
MLBr_02402|M.leprae_Br4923          VRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGG
Mb1099c|M.bovis_AF2122/97           VRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGG
Rv1070c|M.tuberculosis_H37Rv        VRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGG
MAV_1195|M.avium_104                LRTPTIAAVAGHALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGG
TH_4102|M.thermoresistible__bu      TRTPTIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGG
Mflv_2036|M.gilvum_PYR-GCK          TRTPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKLGVLPGMGG
Mvan_4681|M.vanbaalenii_PYR-1       TRTPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKLGVLPGMGG
MAB_1185c|M.abscessus_ATCC_199      VRTPTIAAVSGYALGGGCELAMMCDVIIAAENATFGQPEIKLGVLPGMGG
MSMEG_4077|M.smegmatis_MC2_155      LPQPTVVAVAGYCLGGGLELSLAGDIRIADETAVFGFPEIQIGILPSSGG
                                       * :.**:*:.**** *:::  *: ** :.* ** ***::*:**. **

MMAR_4396|M.marinum_M               SQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAV
MUL_0210|M.ulcerans_Agy99           SQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAV
MLBr_02402|M.leprae_Br4923          SQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAV
Mb1099c|M.bovis_AF2122/97           SQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARAT
Rv1070c|M.tuberculosis_H37Rv        SQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARAT
MAV_1195|M.avium_104                SQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKKV
TH_4102|M.thermoresistible__bu      SQRLTRAIGKAKAMDLILTGRTIDAEEAERSGLVSRVVPADKLLDEAKET
Mflv_2036|M.gilvum_PYR-GCK          SQRLTRAIGKAKAMDLILTGRNMDAEEAERAGLVSRVVPADSLLSEAKAV
Mvan_4681|M.vanbaalenii_PYR-1       SQRLTRAIGKAKAMDLILTGRNMGAEEAERAGLVSRVVPADTLLEEARSV
MAB_1185c|M.abscessus_ATCC_199      SQRLTRAIGKAKAMDMILTGRNMDAAEAERSGLVSRVVATESLLDEAKAV
MSMEG_4077|M.smegmatis_MC2_155      VTRAARTLGYGRATDLILRGRRFGAHQALQWGLLTEVTNKGSHIRTALTI
                                      * :*::* .:* *:** ** :.* :* : **::.*.     :  *   

MMAR_4396|M.marinum_M               ATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAFATADQSEG
MUL_0210|M.ulcerans_Agy99           ATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAFATADQSEG
MLBr_02402|M.leprae_Br4923          ATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQSEG
Mb1099c|M.bovis_AF2122/97           ATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEG
Rv1070c|M.tuberculosis_H37Rv        ATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEG
MAV_1195|M.avium_104                ATTISQMSRSAARMAKEAVNRAFETTLAEGLLYERRLFHSTFATADQSEG
TH_4102|M.thermoresistible__bu      AATIAAMSLSAARMAKEAVNRAFETSLAEGLLFERRVFHSAFATADQSEG
Mflv_2036|M.gilvum_PYR-GCK          AQTIAGMSLSASRMAKEAVDRAFETTLSEGLLYERRLFHSAFATDDQTEG
Mvan_4681|M.vanbaalenii_PYR-1       AKTIAGMSLSASRMAKEAVDRAFETTLTEGLLYERRLFHSAFATDDQTEG
MAB_1185c|M.abscessus_ATCC_199      AKTISEMSLSASMMAKEAVNRAFESSLAEGLLFERRIFHSAFGTADQSEG
MSMEG_4077|M.smegmatis_MC2_155      AHEIAEHDPLVVSVTKQVIHASPDASQAASLLLERLAYAVLNRTTPAAHA
                                    *  *:  .  .  ::*:.:. : ::: : .** **        *   :..

MMAR_4396|M.marinum_M               MAAFIEKRPPNFTHR
MUL_0210|M.ulcerans_Agy99           MAAFIEKRPPNFTHR
MLBr_02402|M.leprae_Br4923          MAAFIEKRAPQFTHR
Mb1099c|M.bovis_AF2122/97           MAAFIEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv        MAAFIEKRAPQFTHR
MAV_1195|M.avium_104                MAAFVEKRAPNFTHR
TH_4102|M.thermoresistible__bu      MAAFTEKRPPKFTHR
Mflv_2036|M.gilvum_PYR-GCK          MNAFSEKRSPNFTHR
Mvan_4681|M.vanbaalenii_PYR-1       MNAFTEKRSPNFTHR
MAB_1185c|M.abscessus_ATCC_199      MAAFVEKRPANFIHR
MSMEG_4077|M.smegmatis_MC2_155      HDEVKQP--------
                                       . :