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TSAQVESQPRSTTHTALYDAWERFVHGDDDVRGVRPEVAISWQRCRDQYRVDPFMSEAPVAVTEVEHSLE HDVVFAELGFCAAAMVHEVSKFGIVVIADATGRVLAEWGDKATLSVAAGSGLAPWFCWSESAVGTNGIGT ALGTRNPLVITREEHWCEAFHDWTCAAVAVRDVVSKEPIASLNISSLRKDMPAAASTWLANAAAHTASKL RNCARDGGAELLAAYSHARARSSDALAAVDTAGKVVIADAVASVPLGVPSNTPAVDPAVRWNPTLPAFID AIRFATKRASHNPDWTGTTQIFTHLADEPSPIGIRPVFRSGNLVGHLITFGVVDGEQVRQVETGLYAVEQ PRRVVGVRDNRMVLLRLPEVLFAEADGNEVWLSTDRGKLRAASSGLDKLDEELTHAGFLRVHRRHIVNLN RIREVERRDKGELVLVMDDPENTMVPVSRRNVRAVRSALCI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3730 | - | - | 100% (462) | helix-turn-helix, Fis-type, putative |
| M. smegmatis MC2 155 | MSMEG_5019 | - | 2e-15 | 33.74% (163) | regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3008 | - | 2e-10 | 21.59% (227) | putative sigma 54 type regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0123 | - | 5e-15 | 29.46% (258) | putative GAF sensor protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2793c | - | 1e-13 | 30.73% (192) | putative transcriptional regulator |
| M. marinum M | MMAR_4913 | - | 2e-08 | 28.30% (159) | putative regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0493 | - | 1e-08 | 28.49% (172) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0790 | - | 5e-15 | 35.58% (163) | putative GAF sensor protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4913|M.marinum_M --MATMRTANEIAAARLSMPALRALRDRFVAGRVDSTYLDSTPVRR---I
MUL_0493|M.ulcerans_Agy99 MLVATMRTANEIAAARLSMPALRALRDRFVAGRVDSTYLYSTPVRR---I
MAB_2793c|M.abscessus_ATCC_199 --MATTRTSARCGPARVSLTSVRDAHELFVTGQVDGSYLESIPLPR---L
Mflv_0123|M.gilvum_PYR-GCK --MPSNVGSPLVPEPAVAVGEDPRSYARLMSAVYDATMAGDRAPARPREV
Mvan_0790|M.vanbaalenii_PYR-1 ------MQGPPVPEPAVAVGEDPRSYARLMSAVYDATMAGHRAPARPREV
MSMEG_3730|M.smegmatis_MC2_155 ----MTSAQVESQPRSTTHTALYDAWERFVHGDDDVRGVRP--------E
: :: . *
MMAR_4913|M.marinum_M VADSWRRSLATGVDPDRGGGQIAQLSDTVERLRSAHPLAPVLPLIRRLLI
MUL_0493|M.ulcerans_Agy99 VADSWRRSLATGVDPDRGGGQIAQLSDTVERLRSAHPLAPVLPLIRRLLI
MAB_2793c|M.abscessus_ATCC_199 VTDSWQRSLATGVDPDRGPGEAAAATQLTE-LRNSHPLARALPVIRRLLV
Mflv_0123|M.gilvum_PYR-GCK IGDSWRRIMASGIEPD-EHAEPVVETGALEMLRRSSGLMEVLDDISHGLG
Mvan_0790|M.vanbaalenii_PYR-1 IGESWQRLIASGMQDR-GPDTTVVEMGGLEMLRRSSGLMDVLDEISRGLE
MSMEG_3730|M.smegmatis_MC2_155 VAISWQRCRDQ-YRVDPFMSEAPVAVTEVEHSLEHDVVFAELGFCAAAMV
: **:* * : * :
MMAR_4913|M.marinum_M DDAADSGVIVAVTSADGTLLWVDGDRRACRKAESMDFVPGADWSERGAGT
MUL_0493|M.ulcerans_Agy99 DDAADSGVIVAVTSADGTLLWVDGDRRACRKAESMDFVPGADWSERGAGT
MAB_2793c|M.abscessus_ATCC_199 DHAADSGALVGVTAADGALLWVEGDSGAGRKAAAMNFVPGADWSERAVGT
Mflv_0123|M.gilvum_PYR-GCK PLVADGENILVVADAKGRVLWRSGSPSVLMNADRLGFVEGANWGERAVGT
Mvan_0790|M.vanbaalenii_PYR-1 SLVADGENILVVADAKGRVLWRSGSPSVLMNADRLGFIEGANWGEGAVGT
MSMEG_3730|M.smegmatis_MC2_155 HEVSKFG-IVVIADATGRVLAEWGDKATLSVAAGSGLAPWFCWSESAVGT
.:. :: :: * * :* *. . * .: *.* ..**
MMAR_4913|M.marinum_M NAPGTALALDRELQIRGSEHFSRLVQPWNCTAVPVHDPSTGVLIGAIDLT
MUL_0493|M.ulcerans_Agy99 NAPGTALALDRELQIRGSEHFSRLVQPWNCTAVPVHDPSTGVLIGAIDLT
MAB_2793c|M.abscessus_ATCC_199 NAPGTALALDREVQIRGSEHFCRLVRPWSCTAVPIHDPLSGTPLGSLDLT
Mflv_0123|M.gilvum_PYR-GCK NAIGTALVSQRAVQVFSAEHFLRSHHSWTCAGAPIRDPRTGQVIGVVDVS
Mvan_0790|M.vanbaalenii_PYR-1 NAIGTALVSQRAVQVFSAEHFLRSHHSWTCAGAPIRDPRTSQVIGVVDVS
MSMEG_3730|M.smegmatis_MC2_155 NGIGTALGTRNPLVITREEHWCEAFHDWTCAAVAVRDVVSKEPIASLNIS
*. **** . : : **: . : *.*:...::* : :. ::::
MMAR_4913|M.marinum_M GG-----------ESVASPQTLALLR----------------ATGVAVES
MUL_0493|M.ulcerans_Agy99 GG-----------ESVASPQTLALLR----------------ATGVAVES
MAB_2793c|M.abscessus_ATCC_199 GG-----------VDIASPQTLALVR----------------ATAVAVEH
Mflv_0123|M.gilvum_PYR-GCK GP-----------AATVHPTTVALVD----------------AVARLAES
Mvan_0790|M.vanbaalenii_PYR-1 GP-----------AATVHPTTVALVD----------------AVARLAES
MSMEG_3730|M.smegmatis_MC2_155 SLRKDMPAAASTWLANAAAHTASKLRNCARDGGAELLAAYSHARARSSDA
. . . * : : * . :
MMAR_4913|M.marinum_M QLALLRSGAVQ-PQPSRQAQLSVLGAQRPSWRVA-GMGPTMLAGRHADIL
MUL_0493|M.ulcerans_Agy99 QLALLRSGAVQ-PQPSRQAQLSVLGAQRPSWRVA-GMGPTMLAGRHADIL
MAB_2793c|M.abscessus_ATCC_199 FIALDYPGRVQ-VDADTGPRLTLLGVGRPVLHTADGERTHRLSGRHAEIL
Mflv_0123|M.gilvum_PYR-GCK HLRVEHDRTLNRLRALTAPILARMGSPALVVDTDGWVAAVDAMPLHHRIL
Mvan_0790|M.vanbaalenii_PYR-1 HLRQEHDRTLNRLRALAAPILARMGSPALAVDTDGWVAAVDAMPLHNRIL
MSMEG_3730|M.smegmatis_MC2_155 LAAVDTAGKVVIADAVASVPLGVPSNTPAVDPAVRWNPTLPAFIDAIRFA
: . * . . . :
MMAR_4913|M.marinum_M VLLDRHPEGLSADHLAVLLDDRELDVVTIRAEMSRLRRVVGEQLIASRPY
MUL_0493|M.ulcerans_Agy99 VLLDRHPEGLSADHLAVLLDDRELDVVTARAEMSRLRRVVGEHLIASRPY
MAB_2793c|M.abscessus_ATCC_199 ALLLRHPEGLSADHLAMLLDENDLDVVTIRAEMSRLRRIVGGELIGSRPY
Mflv_0123|M.gilvum_PYR-GCK LPERLGPGRVRLATLGMCAVEPLPGGWLVRPAGGEDGED-ADEAQPSR--
Mvan_0790|M.vanbaalenii_PYR-1 LPERLGPGRVRLATLGMCAVEPLPGGWLVRPAKGDDAEGGAEQDRPSQ--
MSMEG_3730|M.smegmatis_MC2_155 TKRASHNPDWTGTTQIFTHLADEPSPIGIRPVFRSGNLVGHLITFGVVDG
. . *.
MMAR_4913|M.marinum_M RLTEPIATDVGDVFDAVRRGDLAEA--LRHYAGALLPQSVSP-----GVA
MUL_0493|M.ulcerans_Agy99 RLTEPIATDVGDVFDAVRRGDLAEA--LRHYAGALLPQSVSP-----GIA
MAB_2793c|M.abscessus_ATCC_199 RLLKKVRSDMADVFSALRAGEIANA--MDHYHGELLPRSAAP-----AVA
Mflv_0123|M.gilvum_PYR-GCK ATLDVSDPDRPSLVMVGRSGSWRHD--LSLRHAEILVALALS-----PQG
Mvan_0790|M.vanbaalenii_PYR-1 VTLDVSDPDTPSLIMAGAFGSWRHD--LSLRHAEILCALAFS-----PQG
MSMEG_3730|M.smegmatis_MC2_155 EQVRQVETGLYAVEQPRRVVGVRDNRMVLLRLPEVLFAEADGNEVWLSTD
.. : . : :* .
MMAR_4913|M.marinum_M RVRTELSNTLRA-----AVVASNDADLLANWLRLPEARDD--RQGWRMLY
MUL_0493|M.ulcerans_Agy99 RVRTELSNTLRA-----AVVASNDADLLANWLRLPEAHDD--RQGWRMLY
MAB_2793c|M.abscessus_ATCC_199 RLRLELSTSLRG-----AVLASGDLHLLRRWLDLPEARDN--REGWQGLH
Mflv_0123|M.gilvum_PYR-GCK RSAPQLAEDLYGDRSKVVTVRAEMSRLRKQFAGILATQPY--RFAGAIEL
Mvan_0790|M.vanbaalenii_PYR-1 RSAPQLAEDLYGDRSKVVTVRAEMSRLRKQFAGILAAQPY--RFAASIEL
MSMEG_3730|M.smegmatis_MC2_155 RGKLRAASSGLDKLDEELTHAGFLRVHRRHIVNLNRIREVERRDKGELVL
* . : . . . : : *
MMAR_4913|M.marinum_M DRSPAGSPRRAQAQGHLAGLDFDLA-----------
MUL_0493|M.ulcerans_Agy99 DRSPAGSPRRAQAQGHLAGLDFDLA-----------
MAB_2793c|M.abscessus_ATCC_199 DHPGAGAVARSEARGHLIALDSDLA-----------
Mflv_0123|M.gilvum_PYR-GCK SVRYPADRRMVLPPSNAPVIRAARENG---------
Mvan_0790|M.vanbaalenii_PYR-1 SVRYPADRCLLLPPSNAPAIRTARMAGVPATTHGGQ
MSMEG_3730|M.smegmatis_MC2_155 VMDDPENTMVPVSRRNVRAVRSALCI----------
. . : :