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PSNVGSPLVPEPAVAVGEDPRSYARLMSAVYDATMAGDRAPARPREVIGDSWRRIMASGIEPDEHAEPVV ETGALEMLRRSSGLMEVLDDISHGLGPLVADGENILVVADAKGRVLWRSGSPSVLMNADRLGFVEGANWG ERAVGTNAIGTALVSQRAVQVFSAEHFLRSHHSWTCAGAPIRDPRTGQVIGVVDVSGPAATVHPTTVALV DAVARLAESHLRVEHDRTLNRLRALTAPILARMGSPALVVDTDGWVAAVDAMPLHHRILLPERLGPGRVR LATLGMCAVEPLPGGWLVRPAGGEDGEDADEAQPSRATLDVSDPDRPSLVMVGRSGSWRHDLSLRHAEIL VALALSPQGRSAPQLAEDLYGDRSKVVTVRAEMSRLRKQFAGILATQPYRFAGAIELSVRYPADRRMVLP PSNAPVIRAARENG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0123 | - | - | 100% (435) | putative GAF sensor protein |
| M. gilvum PYR-GCK | Mflv_4955 | - | 5e-30 | 35.37% (246) | putative GAF sensor protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2793c | - | 4e-29 | 35.92% (206) | putative transcriptional regulator |
| M. marinum M | MMAR_4913 | - | 1e-30 | 38.20% (178) | putative regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5019 | - | 1e-166 | 67.37% (426) | regulatory protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0493 | - | 6e-31 | 38.20% (178) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0790 | - | 0.0 | 86.71% (429) | putative GAF sensor protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0123|M.gilvum_PYR-GCK MPSNVGSPLVPEPAVAVGEDPRSYARLMSAVYDATMAGDRAPARPREVIG
Mvan_0790|M.vanbaalenii_PYR-1 ----MQGPPVPEPAVAVGEDPRSYARLMSAVYDATMAGHRAPARPREVIG
MSMEG_5019|M.smegmatis_MC2_155 ---MMPGPSTPEPAVAPGDDPRRYAMLLAEVYDATMSGVRGPARPRQLIE
MMAR_4913|M.marinum_M ---MATMRTANEIAAARLSMPALRALRDRFVAGRVDSTYLDSTPVRRIVA
MUL_0493|M.ulcerans_Agy99 -MLVATMRTANEIAAARLSMPALRALRDRFVAGRVDSTYLYSTPVRRIVA
MAB_2793c|M.abscessus_ATCC_199 ---MATTRTSARCGPARVSLTSVRDAHELFVTGQVDGSYLESIPLPRLVT
. . * . . * . . . . .::
Mflv_0123|M.gilvum_PYR-GCK DSWRRIMASGIEPD-EHAEPVVETGALEMLRRSSGLMEVLDDISHGLGPL
Mvan_0790|M.vanbaalenii_PYR-1 ESWQRLIASGMQDR-GPDTTVVEMGGLEMLRRSSGLMDVLDEISRGLESL
MSMEG_5019|M.smegmatis_MC2_155 DSWKRLLGKGIHPE-QHIPPDVDTSGLDMLRQSSGLMAVLDDVSRGLETV
MMAR_4913|M.marinum_M DSWRRSLATGVDPDRGGGQIAQLSDTVERLRSAHPLAPVLPLIRRLLIDD
MUL_0493|M.ulcerans_Agy99 DSWRRSLATGVDPDRGGGQIAQLSDTVERLRSAHPLAPVLPLIRRLLIDD
MAB_2793c|M.abscessus_ATCC_199 DSWQRSLATGVDPDRGPGEAAAATQLTE-LRNSHPLARALPVIRRLLVDH
:**:* :..*:. : ** : * .* : : *
Mflv_0123|M.gilvum_PYR-GCK VADGENILVVADAKGRVLWRSGSPSVLMNADRLGFVEGANWGERAVGTNA
Mvan_0790|M.vanbaalenii_PYR-1 VADGENILVVADAKGRVLWRSGSPSVLMNADRLGFIEGANWGEGAVGTNA
MSMEG_5019|M.smegmatis_MC2_155 IDDGENILVLADARGRVLWRSGSPRVLKLADRLGFIEGASWAESSVGTNG
MMAR_4913|M.marinum_M AADSGVIVAVTSADGTLLWVDGDRRACRKAESMDFVPGADWSERGAGTNA
MUL_0493|M.ulcerans_Agy99 AADSGVIVAVTSADGTLLWVDGDRRACRKAESMDFVPGADWSERGAGTNA
MAB_2793c|M.abscessus_ATCC_199 AADSGALVGVTAADGALLWVEGDSGAGRKAAAMNFVPGADWSERAVGTNA
*. :: :: * * :** .*. . * :.*: **.*.* ..***.
Mflv_0123|M.gilvum_PYR-GCK IGTALVSQRAVQVFSAEHFLRSHHSWTCAGAPIRDPRTGQVIGVVDVSGP
Mvan_0790|M.vanbaalenii_PYR-1 IGTALVSQRAVQVFSAEHFLRSHHSWTCAGAPIRDPRTSQVIGVVDVSGP
MSMEG_5019|M.smegmatis_MC2_155 IGTALVSHRAVQVFSAEHFLRSHHSWTCAGAPIRDPRTGHVIGIVDVSGP
MMAR_4913|M.marinum_M PGTALALDRELQIRGSEHFSRLVQPWNCTAVPVHDPSTGVLIGAIDLTGG
MUL_0493|M.ulcerans_Agy99 PGTALALDRELQIRGSEHFSRLVQPWNCTAVPVHDPSTGVLIGAIDLTGG
MAB_2793c|M.abscessus_ATCC_199 PGTALALDREVQIRGSEHFCRLVRPWSCTAVPIHDPLSGTPLGSLDLTGG
****. .* :*: .:*** * :.*.*:..*::** :. :* :*::*
Mflv_0123|M.gilvum_PYR-GCK AATVHPTTVALVDAVARLAESHLRVEHDRTLNRLRALTAPILARMGSPAL
Mvan_0790|M.vanbaalenii_PYR-1 AATVHPTTVALVDAVARLAESHLRQEHDRTLNRLRALAAPILARMGSPAL
MSMEG_5019|M.smegmatis_MC2_155 ADTVHPTTVALVDLVARLAESKLREAHDRTLNRLRAVSAPILSRIGRPAL
MMAR_4913|M.marinum_M ESVASPQTLALLRATGVAVESQLALLRSGAVQ-PQPSRQAQLSVLGAQRP
MUL_0493|M.ulcerans_Agy99 ESVASPQTLALLRATGVAVESQLALLRSGAVQ-PQPSRQAQLSVLGAQRP
MAB_2793c|M.abscessus_ATCC_199 VDIASPQTLALVRATAVAVEHFIALDYPGRVQ-VDADTGPRLTLLGVGRP
. * *:**: .. .* : :: . . *: :*
Mflv_0123|M.gilvum_PYR-GCK VVDTDGWVAAVDAMPLHHRILLPERLGPGRVRLATLGMCAVEPLPGGWLV
Mvan_0790|M.vanbaalenii_PYR-1 AVDTDGWVAAVDAMPLHNRILLPERLGPGRVRLATLGMCAVEPLPGGWLV
MSMEG_5019|M.smegmatis_MC2_155 AVDAEGWVAAVDSLPLHNRILLPERGLPGRAWIPSLGMCDVEALPDGWLV
MMAR_4913|M.marinum_M SWRVA-GMGPTMLAGRHADILVLLDRHPEGLSADHLAVLLDDRELDVVTI
MUL_0493|M.ulcerans_Agy99 SWRVA-GMGPTMLAGRHADILVLLDRHPEGLSADHLAVLLDDRELDVVTA
MAB_2793c|M.abscessus_ATCC_199 VLHTADGERTHRLSGRHAEILALLLRHPEGLSADHLAMLLDENDLDVVTI
. . * ** * *.: : .
Mflv_0123|M.gilvum_PYR-GCK RPAGGEDGED-ADEAQPSRAT--LDVSDPDRPSLVMVGRSGSWRHDLSLR
Mvan_0790|M.vanbaalenii_PYR-1 RPAKGDDAEGGAEQDRPSQVT--LDVSDPDTPSLIMAGAFGSWRHDLSLR
MSMEG_5019|M.smegmatis_MC2_155 RVSDDTEASP-----APTRVT--LDLRDGNDPSLEMTGQFGSWRRSISIR
MMAR_4913|M.marinum_M RAEMSRLRRVVGEQLIASRPYRLTEPIATDVGDVFDAVRRGDLAEALRHY
MUL_0493|M.ulcerans_Agy99 RAEMSRLRRVVGEHLIASRPYRLTEPIATDVGDVFDAVRRGDLAEALRHY
MAB_2793c|M.abscessus_ATCC_199 RAEMSRLRRIVGGELIGSRPYRLLKKVRSDMADVFSALRAGEIANAMDHY
* . :: . : .: . *. . :
Mflv_0123|M.gilvum_PYR-GCK HAEILVALALSPQGRSAPQLAEDLYGDRSKVVTVRAEMSRLRKQFAGILA
Mvan_0790|M.vanbaalenii_PYR-1 HAEILCALAFSPQGRSAPQLAEDLYGDRSKVVTVRAEMSRLRKQFAGILA
MSMEG_5019|M.smegmatis_MC2_155 HAEILLVLATARQGRSAPELAGDLYGDRTRVVTVRAEMSRLRKQFVGMIE
MMAR_4913|M.marinum_M AGALLPQSVSPGVARVRTELSNTLRA-----AVVASNDADLLANWLRLPE
MUL_0493|M.ulcerans_Agy99 AGALLPQSVSPGIARVRTELSNTLRA-----AVVASNDADLLANWLRLPE
MAB_2793c|M.abscessus_ATCC_199 HGELLPRSAAPAVARLRLELSTSLRG-----AVLASGDLHLLRRWLDLPE
. :* . . .* :*: * . ..: : * .: :
Mflv_0123|M.gilvum_PYR-GCK TQPYRFAGAIELSVRYPADRRMVLPPSNAPVIRAARENG---------
Mvan_0790|M.vanbaalenii_PYR-1 AQPYRFAASIELSVRYPADRCLLLPPSNAPAIRTARMAGVPATTHGGQ
MSMEG_5019|M.smegmatis_MC2_155 GRPYRFGDAVAVDVRYPRDMSTLLGPSTAPAVRAVRDTA---------
MMAR_4913|M.marinum_M ARDDRQGWRMLYDRSPAGSPRRAQAQGHLAGLDFDLA-----------
MUL_0493|M.ulcerans_Agy99 AHDDRQGWRMLYDRSPAGSPRRAQAQGHLAGLDFDLA-----------
MAB_2793c|M.abscessus_ATCC_199 ARDNREGWQGLHDHPGAGAVARSEARGHLIALDSDLA-----------
: * . . . . :