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PDPAGISVRGVHKSYRDRRVLAGVDLDVAAGTITAVLGPSGCGKTTLLRIMAGFDDPDAGVVRIAGHTVV GDGPVVPAHRRRVGLMPQEGALFPHLSVGGNVAFGLPSRNGVAADVAHWLEVVGLPGLADARPHELSGGQ QQRVALARALAAKPRVLLLDEPFAALDAGLRVRVREDIAEILRAAGTTAVLVTHDQAEALSLADSVALLF DGTVAQHAAPTDLYDRPANLQTARFVGATVELAGTCGDGVARTALGAHPVRVRVPDGPVVVVLRPEQLRA AEAGTPGGDHDAVVRACRFYGADTVLHVVLRDGTAVRLRCAGDARVEAGTVVSVTVDGPVLAYPSPAGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3633 | - | - | 100% (350) | ferric cations import ATP-binding protein FbpC |
| M. smegmatis MC2 155 | MSMEG_6521 | - | 3e-57 | 41.67% (348) | sulfate/thiosulfate import ATP-binding protein CysA 2 |
| M. smegmatis MC2 155 | MSMEG_4530 | cysA | 8e-57 | 49.39% (245) | sulfate ABC transporter, ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 5e-53 | 48.77% (244) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3361 | - | 1e-129 | 69.74% (347) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 5e-53 | 48.77% (244) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01424 | - | 9e-46 | 36.36% (330) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_1655 | - | 1e-56 | 50.21% (243) | sulfate ABC transporter, ATP-binding protein SysA |
| M. marinum M | MMAR_3715 | cysA1 | 7e-53 | 44.75% (295) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 5e-54 | 45.77% (284) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_3667 | - | 1e-128 | 69.74% (347) | PUTATIVE ferric cations import ATP-binding protein FbpC |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 2e-52 | 44.41% (295) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_3091 | - | 1e-132 | 69.32% (352) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3361|M.gilvum_PYR-GCK ---------------------------MTDPMA-LPAASVQAHGIHKAFG
Mvan_3091|M.vanbaalenii_PYR-1 ---------------------------MPGCAV-TDAAAVSARGIHKAFG
MSMEG_3633|M.smegmatis_MC2_155 ---------------------------MP------DPAGISVRGVHKSYR
TH_3667|M.thermoresistible__bu VIKTMKTKPADTSGAGPAVSNPAVSNPDVSAPQ-LRGADVEVQGLHKSFG
Mb2419c|M.bovis_AF2122/97 ---------------------------MT--------YAIVVADATKRYG
Rv2397c|M.tuberculosis_H37Rv ---------------------------MT--------YAIVVADATKRYG
MAV_1785|M.avium_104 ---------------------------MTDAGTDRGDIAITVRDAYKRYG
MMAR_3715|M.marinum_M ---------------------MKKETSLTGPG--TGGHAIVVRDAFKQYG
MUL_3658|M.ulcerans_Agy99 ---------------------------MTGPG--TGGHAIVVRDAFKQYG
MAB_1655|M.abscessus_ATCC_1997 ---------------------------MTAEN------TITVRGANKHYG
MLBr_01424|M.leprae_Br4923 ------------------------------------MASVTFEQATRQFP
: : :
Mflv_3361|M.gilvum_PYR-GCK M--RSVLRGVDLEVPAGSITAILGPSGCGKTTLLRILAGFEDPDLGTVRI
Mvan_3091|M.vanbaalenii_PYR-1 G--RTVLCGVDLEMAAGSITAVLGPSGCGKTTLLRILAGFEDPDSGTVRI
MSMEG_3633|M.smegmatis_MC2_155 D--RRVLAGVDLDVAAGTITAVLGPSGCGKTTLLRIMAGFDDPDAGVVRI
TH_3667|M.thermoresistible__bu A--KAVLRGVDLTVSAGTLTAVLGPSGCGKTTLLRILAGFDDPDAGTVRI
Mb2419c|M.bovis_AF2122/97 D--FVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITI
Rv2397c|M.tuberculosis_H37Rv D--FVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITI
MAV_1785|M.avium_104 D--FVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTVTI
MMAR_3715|M.marinum_M D--FVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGNITI
MUL_3658|M.ulcerans_Agy99 D--FVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGNITI
MAB_1655|M.abscessus_ATCC_1997 D--FAALDNIDFDVPSGSLTALLGPSGSGKSTLLRSIAGLDNPDSGTITI
MLBr_01424|M.leprae_Br4923 DTDRPALDRLDLDVDDGEFVVVVGPSGCGKTTSLRMVAGLETLDSGCIRI
.* :*: : * :..::****.**:* ** :**:: * * : *
Mflv_3361|M.gilvum_PYR-GCK AGETVASDAVTVPVHRRRVGLMPQEGALFPHLSVGENVAFGLGR--ADRE
Mvan_3091|M.vanbaalenii_PYR-1 AGETVAGDGAAVPVHRRRVGLMPQEGALFPHLSVGENVAFGLGR--ADRA
MSMEG_3633|M.smegmatis_MC2_155 AGHTVVGDGPVVPAHRRRVGLMPQEGALFPHLSVGGNVAFGLP----SRN
TH_3667|M.thermoresistible__bu GGHTLAGGGAPVPAHRRRVGLMPQEGALFPHLSVAENIAFGLRR--TRRA
Mb2419c|M.bovis_AF2122/97 NGRDVTR----VPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPKA
Rv2397c|M.tuberculosis_H37Rv NGRDVTR----VPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPKA
MAV_1785|M.avium_104 YGRDVTR----VPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKVRKRPKA
MMAR_3715|M.marinum_M NGRDVTR----VPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRKRPKA
MUL_3658|M.ulcerans_Agy99 NGRDVTR----VPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRKRPKA
MAB_1655|M.abscessus_ATCC_1997 NGRDVTG----VPPQRRDIGFVFQHYAAFKHLTVWENVAFGLKIRKKPKA
MLBr_01424|M.leprae_Br4923 GDRDVTH----VDPKDRDVAMVFQNYALYPHMTVAQNLGFALKISKISKA
.. :. * : * :.:: *. * : *::* *:.:.* :
Mflv_3361|M.gilvum_PYR-GCK HARAQVAHWLEVVGLGDLARARPHEISGGQQQRVALARALAARPRVLLLD
Mvan_3091|M.vanbaalenii_PYR-1 TASAQVAHWLDVVGLEGLADARPHEISGGQQQRVALARALAARPRVLLLD
MSMEG_3633|M.smegmatis_MC2_155 GVAADVAHWLEVVGLPGLADARPHELSGGQQQRVALARALAAKPRVLLLD
TH_3667|M.thermoresistible__bu GRADTVRYWLEVVGLEGAAEARPHELSGGQQQRVALARALAAEPRVLLLD
Mb2419c|M.bovis_AF2122/97 EIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLD
Rv2397c|M.tuberculosis_H37Rv EIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLD
MAV_1785|M.avium_104 EIKAKVDNLLEVVGLSGFQGRYPNQLSGGQRQRMALARALAVDPQVLLLD
MMAR_3715|M.marinum_M EIRDKVDNLLEVVGLSGFHGRYPNQLSGGQRQRMALARALAVDPEVLLLD
MUL_3658|M.ulcerans_Agy99 EIRDKVDNLLEVVGLSGFHGRYPDQLSGGQRQRMALARALAVDPEVLLLD
MAB_1655|M.abscessus_ATCC_1997 EIKKKVDDLLEVVGLSGFHTRYPAQLSGGQRQRMALARALAVDPQVLLLD
MLBr_01424|M.leprae_Br4923 EIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVAMGRAIVRRPQVFLMD
: .::.* * ::****:**:*:.**:. *.*:*:*
Mflv_3361|M.gilvum_PYR-GCK EPFAALDAGLRVRVREDIAAILRDTGTTAVLVTHDQSEALSLADSVALLI
Mvan_3091|M.vanbaalenii_PYR-1 EPFAALDAGLRVRVREDIATILRDTGTTALLVTHDQSEALSLADSVALLI
MSMEG_3633|M.smegmatis_MC2_155 EPFAALDAGLRVRVREDIAEILRAAGTTAVLVTHDQAEALSLADSVALLF
TH_3667|M.thermoresistible__bu EPFVALDAGLRVRVREEIAAILRAAGTTAVLVTHDQSEALSLADSVALLM
Mb2419c|M.bovis_AF2122/97 EPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLH
Rv2397c|M.tuberculosis_H37Rv EPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLH
MAV_1785|M.avium_104 EPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLN
MMAR_3715|M.marinum_M EPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLN
MUL_3658|M.ulcerans_Agy99 EPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLN
MAB_1655|M.abscessus_ATCC_1997 EPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLN
MLBr_01424|M.leprae_Br4923 EPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHDQVEAMTMGDRVAVLC
**: *** :* * : : .*:: ***** **: :.* :*:*
Mflv_3361|M.gilvum_PYR-GCK GGAVAQHGTPADLYHRPGTLTSARFIG--NTVEITGTAESGTVHTALGAL
Mvan_3091|M.vanbaalenii_PYR-1 DGVIAQHGTPADLYERPGTLANARFIG--STVEIAGTADAGTVHTSLGPL
MSMEG_3633|M.smegmatis_MC2_155 DGTVAQHAAPTDLYDRPANLQTARFVG--ATVELAGTCGDGVARTALGAH
TH_3667|M.thermoresistible__bu DGRLAQVGAPADIYERPATPAAARFVG--ATVELPGQARDGVVHTALGSH
Mb2419c|M.bovis_AF2122/97 KGRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNGSLVRPHDIRVGRTP
Rv2397c|M.tuberculosis_H37Rv KGRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNGSLVRPHDIRVGRTP
MAV_1785|M.avium_104 QGRIEQIGSPTEVYDAPTNAFVMSFLG--AVSTLNGTLVRPHDIRVGRTP
MMAR_3715|M.marinum_M SGRIEQVGSPTEVYDAPANAFVMSFLG--AVSALNGALVRPHDIRVGRTP
MUL_3658|M.ulcerans_Agy99 SGRIEQVGSPTEVYDAPTNAFVMSFLG--AVSALNGALVRPHDIRVGRTP
MAB_1655|M.abscessus_ATCC_1997 KGRIEQVGSPEDLYDRPANSFVMSFLG--PVAKLNGILVRPHDIRVGRNA
MLBr_01424|M.leprae_Br4923 YGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVTLSIVDSSVLLGDWPI
* : * .:* ::*. * . *:* :
Mflv_3361|M.gilvum_PYR-GCK RSKVTVGDGP--AVVVLRPEQLR---VGTDGSGSPARVRACRFYGADTVV
Mvan_3091|M.vanbaalenii_PYR-1 RTRGPVADGP--AVVALRPEQLR---FGTGLSGTPGRVTARRFYGADTVV
MSMEG_3633|M.smegmatis_MC2_155 PVRVRVPDGP--VVVVLRPEQLRAAEAGTPGGDHDAVVRACRFYGADTVL
TH_3667|M.thermoresistible__bu PARLPVPDGP--VVVVLRPEELR--LERSRDGVPAAAVQSVRFYGPQSAV
Mb2419c|M.bovis_AF2122/97 NMAVAAADGTAGSTGVLRAVVDR----VVVLGFEVRVELTSAATGGAFTA
Rv2397c|M.tuberculosis_H37Rv NMAVAAADGTAGSTGVLRAVVDR----VVVLGFEVRVELTSAATGGAFTA
MAV_1785|M.avium_104 EMAVAAEDGTAESTGVARAIVDR----VVKLGFEVRVELTSAATGGPFTA
MMAR_3715|M.marinum_M EMAVAAADGTGESTGVTRAVVDR----IVVLGFEVRVELTSAATGGAFTA
MUL_3658|M.ulcerans_Agy99 EMAVAAADGTGESTGVTRAVVDR----IVVLGFEVRVELTSAATGGAFTA
MAB_1655|M.abscessus_ATCC_1997 DLARAAAEGTGETTGVTKATVDR----VVYLGFEVRVELTSAATGEQFTA
MLBr_01424|M.leprae_Br4923 RIPREIASAASEVIIGVRPEHFELGSLGVEVEIDMVEELGADAYLYGRIA
... :. .
Mflv_3361|M.gilvum_PYR-GCK HVTLDDGTALQVRSPGAPGLDEGADVTVDVVG--DVLAYPSPTGRERVSL
Mvan_3091|M.vanbaalenii_PYR-1 HVALTDGTALRLRSPVPTGLDDGSPVTIEVAG--DVLAYPSPTSGQRVPL
MSMEG_3633|M.smegmatis_MC2_155 HVVLRDGTAVRLRCAGDARVEAGTVVSVTVDG--PVLAYPSPAGG-----
TH_3667|M.thermoresistible__bu QVRLADDTVVTVLTAGDAGVSVGEPVGVRVDG--SVLAYPAPGRPPARS-
Mb2419c|M.bovis_AF2122/97 QITRGDAEALALR-EGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVT
Rv2397c|M.tuberculosis_H37Rv QITRGDAEALALR-EGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVT
MAV_1785|M.avium_104 QITRGDAEALALR-EGDTVYVRATRVPPITAGATTVPAVSRDGADEATLT
MMAR_3715|M.marinum_M QITRGDAEALALQ-EGDTVYVRATRVPPIAGA---APAVPDDGAGSTPSA
MUL_3658|M.ulcerans_Agy99 QITRGDAEALALQ-EGDTVYVRATRVPPIAGA---APAVPDDGAGSTPRA
MAB_1655|M.abscessus_ATCC_1997 QITRGDAEALGLR-EGDPVYVRVTRVP--------------DVGELAEVA
MLBr_01424|M.leprae_Br4923 GASKVTDQLVVARVDGRNPPAKGSRVRLYTEPG-NVHFFGVDGHRIS---
: *
Mflv_3361|M.gilvum_PYR-GCK GEAGS---
Mvan_3091|M.vanbaalenii_PYR-1 GEAGS---
MSMEG_3633|M.smegmatis_MC2_155 --------
TH_3667|M.thermoresistible__bu --------
Mb2419c|M.bovis_AF2122/97 ST------
Rv2397c|M.tuberculosis_H37Rv ST------
MAV_1785|M.avium_104 SA------
MMAR_3715|M.marinum_M AQIGVGGQ
MUL_3658|M.ulcerans_Agy99 AQIGVGGQ
MAB_1655|M.abscessus_ATCC_1997 S-------
MLBr_01424|M.leprae_Br4923 --------