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MNQLLQYQSLLWEGLWTTVLVTVFGILIAVVVAFVVGFMRLSRHRIVRAPAYVFVEFFRGTSILVQLAWV VYALPFLGVRFTDNLVAGIVVLGLNEGAYAAEIVRGAIASRPRGQTEAAVALGMKPAQRMRRILVPQSIP VMLPSFGNVAVDLLKATPLVYFIGVADFTANGLAIRTETQDTTTILLTLLVVYFILALILAAITRWLENR FGLEHRRRGLLRGSPRPVFRPMIGSTS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3548 | ehuC | - | 100% (237) | ectoine/hydroxyectoine ABC transporter, permease protein EhuC |
| M. smegmatis MC2 155 | MSMEG_5369 | ehuC | 7e-45 | 44.29% (210) | ectoine/hydroxyectoine ABC transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_5318 | - | 5e-33 | 38.12% (202) | glutamine ABC transporter, permease/substrate-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0961 | pstA2 | 3e-07 | 22.01% (209) | phosphate ABC transporter transmembrane protein |
| M. gilvum PYR-GCK | Mflv_3164 | - | 3e-31 | 36.82% (201) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | Rv0936 | pstA2 | 3e-07 | 22.01% (209) | phosphate ABC transporter transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0277c | - | 7e-29 | 34.45% (209) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0061 | glnQ | 6e-20 | 30.60% (232) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 1e-19 | 32.21% (208) | amino acid ABC transporter, permease protein, |
| M. thermoresistible (build 8) | TH_3737 | - | 2e-26 | 35.65% (216) | PUTATIVE glutamate transporter permease protein GluD |
| M. ulcerans Agy99 | MUL_4375 | proW | 5e-05 | 22.07% (213) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. vanbaalenii PYR-1 | Mvan_4703 | - | 9e-34 | 40.59% (202) | polar amino acid ABC transporter, inner membrane subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0061|M.marinum_M ----------MLAVSATILIVLG--LALAAPALADHNQCAPAGVDSAMVL
MAV_0059|M.avium_104 MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKSAAVL
Mflv_3164|M.gilvum_PYR-GCK -----------------------------MGAAEGSSGCRPGPPGNRRRR
Mvan_4703|M.vanbaalenii_PYR-1 -----------------------------MRATR-SGHVEAGGTPSIRCR
MSMEG_3548|M.smegmatis_MC2_155 --------------------------------------------------
Mb0961|M.bovis_AF2122/97 --------------------------------------------------
Rv0936|M.tuberculosis_H37Rv --------------------------------------------------
TH_3737|M.thermoresistible__bu --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 -------------------------------------------------M
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M PADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGTLSDAP
MAV_0059|M.avium_104 PENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTLSGAP
Mflv_3164|M.gilvum_PYR-GCK LQILIAGLLIGLFGAVLALPGTAGAEGE-----------TYTVATDTTFA
Mvan_4703|M.vanbaalenii_PYR-1 VAAVLTVILATVLGAGLLGAATASAQEQ-----------NYVIATDTTFA
MSMEG_3548|M.smegmatis_MC2_155 --------------------------------------------------
Mb0961|M.bovis_AF2122/97 --------------------------------------------------
Rv0936|M.tuberculosis_H37Rv --------------------------------------------------
TH_3737|M.thermoresistible__bu --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 FRAIVLALLALVAVAGCAAPTQEP----------------LRVGTEGVYA
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M PNTCIN-STGQFTGFDNELLRAIAAKLGLQVRFVGTDFSGLLAQVAARRF
MAV_0059|M.avium_104 PNVCIT-PTGQYSGFDNQLLRAIAGKLGLQVRFVGTDFAGLLAQVASRRF
Mflv_3164|M.gilvum_PYR-GCK PFEFQD-ASGEFVGIDMDLIRAIAEDQGFTVDIKPLGFDAALQAVQANQV
Mvan_4703|M.vanbaalenii_PYR-1 PFEFQD-AGGELVGIDMDLIREIAKDQGFTVDIRPLGFDAALQAVQANQA
MSMEG_3548|M.smegmatis_MC2_155 --------------------------------------------------
Mb0961|M.bovis_AF2122/97 ---------------------------------------------MGESA
Rv0936|M.tuberculosis_H37Rv ---------------------------------------------MGESA
TH_3737|M.thermoresistible__bu -------------------------------------------------M
MAB_0277c|M.abscessus_ATCC_199 PFSFHDGHTGELTGYDVDVARAVGEKLGRPVEFVEIPWDAIFAGLDAERF
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M DVGSASVKLTEARRRTVAFTN-GYDFGYYSLVVPPGSAITKFSDLAPGQR
MAV_0059|M.avium_104 DVGSSSIKATDERRQTVAFTN-GYDFGYYALVVPPGSAIKEFTDLAAGQR
Mflv_3164|M.gilvum_PYR-GCK DGVIAGMSITEERKKVFDFSEPYFESGIQMAVLEDNEDITSYEDLR-GQR
Mvan_4703|M.vanbaalenii_PYR-1 AGVIAGMSITDERKAVFDFSDPYFESGVQMAVLDSNDTIASYEDLR-GQR
MSMEG_3548|M.smegmatis_MC2_155 --------------------------------------------------
Mb0961|M.bovis_AF2122/97 ESGSRQLPAMSPPRRSVAYRR-----------------------------
Rv0936|M.tuberculosis_H37Rv ESGSRQLPAMSPPRRSVAYRR-----------------------------
TH_3737|M.thermoresistible__bu STTSVLFDAPGPRAR-----------------------------------
MAB_0277c|M.abscessus_ATCC_199 DVVANQVTITPARKAKYDISTPYAVGEGVIVTRADDNSIHSLSDVR----
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M IGVVQGTVEESY---VVNSLHLQPVKYPDFATVYGNLKTHQIDAWVAPGN
MAV_0059|M.avium_104 IGVVQGTVEESY---VVDTLHLQPVKYPDFATVYASLKTRQIDAWVAPAG
Mflv_3164|M.gilvum_PYR-GCK VSVKNGTQGSDFANSIKDQYGFEVVSFADSSTMFDEVKTGNSVAVFEDYP
Mvan_4703|M.vanbaalenii_PYR-1 VAVKNGTEGAEFAESIKDKYGFQIVSFADSASMFEEVKTGNSVAVFEDYP
MSMEG_3548|M.smegmatis_MC2_155 --------------------------------------------------
Mb0961|M.bovis_AF2122/97 -------------------------------------KIVDALWWAACVC
Rv0936|M.tuberculosis_H37Rv -------------------------------------KIVDALWWAACVC
TH_3737|M.thermoresistible__bu --------------------------------------RRNRIATAVTVV
MAB_0277c|M.abscessus_ATCC_199 -GKVAAENATSNWSQIARDAGARVEAVEGFTQSITLLSQGRVDVVINDSI
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M QAEAAIRPGDPAVLVANTFGAGDFVAYVVARDNRPLLDALNSGLDAVIAD
MAV_0059|M.avium_104 QAATTIQPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNSGLDAVIAD
Mflv_3164|M.gilvum_PYR-GCK VLLYGIAQGNGFKTVTPKEDPTGYGFAVNKGQNAELLQKFNDGLENLKAQ
Mvan_4703|M.vanbaalenii_PYR-1 VLLYGIQQGNGFKTVTPKEQGSNYGFAVNKGRNAELLTKFNEGLKNLKES
MSMEG_3548|M.smegmatis_MC2_155 --------------------------------------------------
Mb0961|M.bovis_AF2122/97 CLAVVITPTLWMLIGVVSRAVPVFHWSVLVQDS-----------------
Rv0936|M.tuberculosis_H37Rv CLAVVITPTLWMLIGVVSRAVPVFHWSVLVQDS-----------------
TH_3737|M.thermoresistible__bu VVAAVFGVVLHRLAAQGQLAADKWTPFLN---------------------
MAB_0277c|M.abscessus_ATCC_199 AVYAYLASTGDPAVKIAGATGQRSEQGFAARKNSGLLPDLDKALDQLAAD
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M GTWSQLYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAAHRHKPVGPAA
MAV_0059|M.avium_104 GTWSNLYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAASQHHKAVGPAA
Mflv_3164|M.gilvum_PYR-GCK GRYDEILQTYLG--------------------------------------
Mvan_4703|M.vanbaalenii_PYR-1 GRYDAIIESYLG--------------------------------------
MSMEG_3548|M.smegmatis_MC2_155 --------------------------------------------------
Mb0961|M.bovis_AF2122/97 --------------------------------------------------
Rv0936|M.tuberculosis_H37Rv --------------------------------------------------
TH_3737|M.thermoresistible__bu --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 GTLTRISQKYLKTDASG------------------------------TTK
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M PKSALTQLRDSFFDWDMYRQAIPTLFKTGLPNTLILTLSASIIGLALGMA
MAV_0059|M.avium_104 PKSTLAQLRDSFFDWDMYRQAIPTLLRTGLPNTLILTFSASVIGLVLGMV
Mflv_3164|M.gilvum_PYR-GCK --EEAAESDDSLFG---LIKSTSPMLLAGLKMTIILTVVSIFFALILGVI
Mvan_4703|M.vanbaalenii_PYR-1 --EEAAETDNSFFG---LLKSTFPILMEGLRLTLILTVVSIAIALVLGVM
MSMEG_3548|M.smegmatis_MC2_155 ---------------MNQLLQYQSLLWEGLWTTVLVTVFGILIAVVVAFV
Mb0961|M.bovis_AF2122/97 -------------------QGNGGGLRNAIIGTAVLAIGVILVGGTVSVL
Rv0936|M.tuberculosis_H37Rv -------------------QGNGGGLRNAIIGTAVLAIGVILVGGTVSVL
TH_3737|M.thermoresistible__bu ------------------ANVWKTYLLPGLRGTLVAAGISIVLAMILGVL
MAB_0277c|M.abscessus_ATCC_199 PQAGKGDSGSTRSDTQLVLDNLWPMARAMITVTLPLTAISFVIGLVIALG
MUL_4375|M.ulcerans_Agy99 ---------------MHYLMTHLGTAWALTMVHLRLSLIPVLIGTAIAIP
: .. :..
MMAR_0061|M.marinum_M LAIAGISHQR-WLRWPARVYTDIFRGLPEVVIILIIGLGVGPIVGGLTNN
MAV_0059|M.avium_104 LAVAGISHAR-WLRWPARVYTDVFRGLPEVVIILLIGLGIGPIVGGLTNN
Mflv_3164|M.gilvum_PYR-GCK FGLARVSRSI-WLRAIGTTFVDIFRGTPLLVQAFFIYFGIPATMG--FQM
Mvan_4703|M.vanbaalenii_PYR-1 FGLFRVSRSI-WLRAIGTTYVDIFRGTPLLVQAFFIYFGVPSALD--FRM
MSMEG_3548|M.smegmatis_MC2_155 VGFMRLSRHR-IVRAPAYVFVEFFRGTSILVQLAWVVYALP-FLGVRFTD
Mb0961|M.bovis_AF2122/97 TGIYLSEFATGKTRSILRGAYEVLSGIPSIVLGYVGYLALVVYFD---WG
Rv0936|M.tuberculosis_H37Rv TGIYLSEFATGKTRSILRGAYEVLSGIPSIVLGYVGYLALVVYFD---WG
TH_3737|M.thermoresistible__bu FGVGRLSPWR-VVRWPCAMLVEFFRAVPVLIMMIFAWQFYSLFNVVPARH
MAB_0277c|M.abscessus_ATCC_199 VALARMSGHR-VVTGLARIYISVIRGTPLLLQLFLIFFALPEFGV---KI
MUL_4375|M.ulcerans_Agy99 LGLFVQHAPT--LRRLTTATASVVFTIPSLALFVVLPLIIKMRIL-----
.. ... . :
MMAR_0061|M.marinum_M NPYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLEASRALGFSYSAAMRL
MAV_0059|M.avium_104 NPYPLGIAALGMMAAAYIGEILRSGIQSVDPGQLEASRALGFSYATAMRL
Mflv_3164|M.gilvum_PYR-GCK SAVTAGIITLSLNAGAYMTEIVRGGILSVDKGQMEAARSLGIGYLPTMRK
Mvan_4703|M.vanbaalenii_PYR-1 TALTAGIITLSLNAGAYMTEIVRGGIQSVDKGQMEAARSLGIGYLPTMRK
MSMEG_3548|M.smegmatis_MC2_155 N-LVAGIVVLGLNEGAYAAEIVRGAIASRPRGQTEAAVALGMKPAQRMRR
Mb0961|M.bovis_AF2122/97 FSLAAGVLVLSVMSIPYIAKATESALAQVPTSYREAAEALGLPAGWALRK
Rv0936|M.tuberculosis_H37Rv FSLAAGVLVLSVMSIPYIAKATESALAQVPTSYREAAEALGLPAGWALRK
TH_3737|M.thermoresistible__bu SVLAGVVTGLTLYNGAVIAEAIRTGVNNLPRGQAEAAYALGMRWRQTMWS
MAB_0277c|M.abscessus_ATCC_199 SPFPAAVIAFSLNVGGYAAEIIRSSILSIPRGQWEAASSLGMSYSTTLWR
MUL_4375|M.ulcerans_Agy99 -QEANVIIALSAYTTALLVRAVLEALDAVPAQVRDAAVAVGYSPIARMLK
: : . .: :*: ::* :
MMAR_0061|M.marinum_M VVVPQGVRRVLP-ALVNQFIALLKASALVYFLGLI----------AQQRE
MAV_0059|M.avium_104 VVVPQGVRRVLP-ALVNQFIALLKASALVYFLGLV----------ADQRE
Mflv_3164|M.gilvum_PYR-GCK VILPQAIRTMIP-SYINQFVITLKDTSILSVLG--------------IAE
Mvan_4703|M.vanbaalenii_PYR-1 VILPQAIRTMIP-SYVNQFVITLKDTSILSVIG--------------IAE
MSMEG_3548|M.smegmatis_MC2_155 ILVPQSIPVMLP-SFGNVAVDLLKATPLVYFIG--------------VAD
Mb0961|M.bovis_AF2122/97 IVLKTAMPGIVTGMLVALALAIGETAPLLYTAGWSNSPPTGQLTDSPVGY
Rv0936|M.tuberculosis_H37Rv IVLKTAMPGIVTGMLVALALAIGETAPLLYTAGWSNSPPTGQLTDSPVGY
TH_3737|M.thermoresistible__bu IELPQAITSMLP-VLVSQMVVVLKDTALGYQIS--------------YLE
MAB_0277c|M.abscessus_ATCC_199 IVIPQASRVAVP-PLSNTLISLVKDTSLASAIL--------------VTD
MUL_4375|M.ulcerans_Agy99 VELPLSIPVLVS-GLRVVVVTNIAMVSVGAVIGIG------------GLG
: : . :. : .:
MMAR_0061|M.marinum_M LFQVGRDLNAQTGN-LSPLVAAGIFYLMLTVPLTHLVNYIDAR--LRRGR
MAV_0059|M.avium_104 LFQVGRDLNAETGN-LSPLVAAGACYLILTVPLTHLVNMIDAR--LRRGR
Mflv_3164|M.gilvum_PYR-GCK LTQSGRIIIAGNYKAFEMWLIVGVIYFIVIMALTKLSDRLERR--LVK--
Mvan_4703|M.vanbaalenii_PYR-1 LTQTGRLIIARNYQSFTMWLIIGVIYFIVIMALTKLSDRLERR--LVK--
MSMEG_3548|M.smegmatis_MC2_155 FTANGLAIRTETQDTTTILLTLLVVYFILALILAAITRWLENRFGLEHRR
Mb0961|M.bovis_AF2122/97 LTYPIWTFYNQPSKSAQDLSYDAALLLIVFLLLLIFIGRLINW--LSRRR
Rv0936|M.tuberculosis_H37Rv LTYPIWTFYNQPSKSAQDLSYDAALLLIVFLLLLIFIGRLINW--LSRRR
TH_3737|M.thermoresistible__bu VVRQGRIVGTAFQNYIPTLIVVAVLMIALNFALSALAGWIERR--MRRSR
MAB_0277c|M.abscessus_ATCC_199 VMRTAQVAAAPTFQFFTLYVTAGVYYWIVCMAMSAVQDRLEQR--LEKSV
MUL_4375|M.ulcerans_Agy99 TWFTAGYLMDKSDQIVAGITVMFVLAILIDMVLNVAGRLATPWERSSRGR
. : . : :
MMAR_0061|M.marinum_M RRLDPEDPPGVVSSTIGEEMT-
MAV_0059|M.avium_104 AAVDPEEPAEMLT--FGQEIT-
Mflv_3164|M.gilvum_PYR-GCK ----------------------
Mvan_4703|M.vanbaalenii_PYR-1 ----------------------
MSMEG_3548|M.smegmatis_MC2_155 RGLLRGSPRPVFRPMIGSTS--
Mb0961|M.bovis_AF2122/97 WDV-------------------
Rv0936|M.tuberculosis_H37Rv WDV-------------------
TH_3737|M.thermoresistible__bu RGPAPARAHAVEQDGVPGAPVR
MAB_0277c|M.abscessus_ATCC_199 AR--------------------
MUL_4375|M.ulcerans_Agy99 RRFRSPIVGGAR----------