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MRATRSGHVEAGGTPSIRCRVAAVLTVILATVLGAGLLGAATASAQEQNYVIATDTTFAPFEFQDAGGEL VGIDMDLIREIAKDQGFTVDIRPLGFDAALQAVQANQAAGVIAGMSITDERKAVFDFSDPYFESGVQMAV LDSNDTIASYEDLRGQRVAVKNGTEGAEFAESIKDKYGFQIVSFADSASMFEEVKTGNSVAVFEDYPVLL YGIQQGNGFKTVTPKEQGSNYGFAVNKGRNAELLTKFNEGLKNLKESGRYDAIIESYLGEEAAETDNSFF GLLKSTFPILMEGLRLTLILTVVSIAIALVLGVMFGLFRVSRSIWLRAIGTTYVDIFRGTPLLVQAFFIY FGVPSALDFRMTALTAGIITLSLNAGAYMTEIVRGGIQSVDKGQMEAARSLGIGYLPTMRKVILPQAIRT MIPSYVNQFVITLKDTSILSVIGIAELTQTGRLIIARNYQSFTMWLIIGVIYFIVIMALTKLSDRLERRL VK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4703 | - | - | 100% (492) | polar amino acid ABC transporter, inner membrane subunit |
| M. vanbaalenii PYR-1 | Mvan_5576 | - | 3e-60 | 31.47% (483) | polar amino acid ABC transporter, inner membrane subunit |
| M. vanbaalenii PYR-1 | Mvan_6047 | - | 1e-39 | 28.45% (478) | polar amino acid ABC transporter, inner membrane subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0419c | glnH | 6e-11 | 26.13% (222) | glutamine-binding lipoprotein |
| M. gilvum PYR-GCK | Mflv_3164 | - | 0.0 | 78.53% (475) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | Rv0411c | glnH | 7e-11 | 26.13% (222) | glutamine-binding lipoprotein |
| M. leprae Br4923 | MLBr_00303 | glnH | 1e-08 | 23.94% (213) | putative glutamine-binding protein |
| M. abscessus ATCC 19977 | MAB_0277c | - | 7e-57 | 31.07% (486) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0061 | glnQ | 3e-37 | 27.09% (539) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 7e-38 | 28.48% (474) | amino acid ABC transporter, permease protein, |
| M. smegmatis MC2 155 | MSMEG_5318 | - | 0.0 | 85.75% (456) | glutamine ABC transporter, permease/substrate-binding protein |
| M. thermoresistible (build 8) | TH_0515 | - | 6e-38 | 28.15% (476) | amino acid ABC transporter, permease protein, 3-TM region, |
| M. ulcerans Agy99 | MUL_2809 | glnH | 1e-11 | 27.35% (223) | glutamine-binding lipoprotein GlnH |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4703|M.vanbaalenii_PYR-1 --------------------------------MRATRSGHVEAGGTPSIR
MSMEG_5318|M.smegmatis_MC2_155 -------------------------------------------------M
Mflv_3164|M.gilvum_PYR-GCK -------------------------------MGAAEGSSGCRPGPPGNRR
MMAR_0061|M.marinum_M ---------------MLAVSATILIVLG--LALAAPALADHNQCAPAGVD
MAV_0059|M.avium_104 -----MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPK
TH_0515|M.thermoresistible__bu -------VTRAAVVAVIALLVGSLTAGG--TVLAAPAAATVDQCAPPGVQ
Mb0419c|M.bovis_AF2122/97 -MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGME
Rv0411c|M.tuberculosis_H37Rv -MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGME
MUL_2809|M.ulcerans_Agy99 -MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLPLPTPVGME
MLBr_00303|M.leprae_Br4923 MMTRQFKIQRACS---VLATAMMLAACGHAELLTVASMPTLPPPTPVGME
MAB_0277c|M.abscessus_ATCC_199 -------------------------------------------------M
Mvan_4703|M.vanbaalenii_PYR-1 CRVAAVLTVILATVLGAGLLGAATASAQEQN--------------YVIAT
MSMEG_5318|M.smegmatis_MC2_155 LAVAALVGLIP-------MVAPATASAEGET--------------YVVAT
Mflv_3164|M.gilvum_PYR-GCK RRLQILIAGLLIGLFGAVLALPGTAGAEGET--------------YTVAT
MMAR_0061|M.marinum_M SAMVLPADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGT
MAV_0059|M.avium_104 SAAVLPENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGT
TH_0515|M.thermoresistible__bu SASPLPTNLAAAEAGP-GVDRYTTDGVVPLDNIDPSALRLRVPGVLTVGT
Mb0419c|M.bovis_AF2122/97 IMPPQPP-LPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVGL
Rv0411c|M.tuberculosis_H37Rv IMPPQPP-LPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVGL
MUL_2809|M.ulcerans_Agy99 VMPPEPP-LPADSSSQDCDPTASLRPFPTKAEADAAVADIRARGRLIVGL
MLBr_00303|M.leprae_Br4923 QVPPELL-LPQDNTEEDCDPTASLRPFPTKAEADAAVAEIRARGRLIVGL
MAB_0277c|M.abscessus_ATCC_199 FRAIVLALLALVAVAGCAAPTQEP---------------------LRVGT
.
Mvan_4703|M.vanbaalenii_PYR-1 DTTFAPFEFQD-AGGELVGIDMDLIREIAKDQG---FTVDIRPLGFDAAL
MSMEG_5318|M.smegmatis_MC2_155 DITFAPFEFQD-ASGKFVGIDIDLINEIAADQN---FTVTIKPLGFDAAL
Mflv_3164|M.gilvum_PYR-GCK DTTFAPFEFQD-ASGEFVGIDMDLIRAIAEDQG---FTVDIKPLGFDAAL
MMAR_0061|M.marinum_M LSDAPPNTCIN-STGQFTGFDNELLRAIAAKLG---LQVRFVGTDFSGLL
MAV_0059|M.avium_104 LSGAPPNVCIT-PTGQYSGFDNQLLRAIAGKLG---LQVRFVGTDFAGLL
TH_0515|M.thermoresistible__bu LSDAPPSICIN-SLGEFTGFDNELLRAIAAKLG---LQISFVGTEFSALL
Mb0419c|M.bovis_AF2122/97 DIGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERV
Rv0411c|M.tuberculosis_H37Rv DIGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERV
MUL_2809|M.ulcerans_Agy99 DIGSNLFSFRDPITGEITGFDVDIASEVARDIFGGPTHVEYRILSAAERI
MLBr_00303|M.leprae_Br4923 EIGSNLFSFRDPITGEITGFDIDIAGEVARDIFGTPSHMEYRILSTAARI
MAB_0277c|M.abscessus_ATCC_199 EGVYAPFSFHDGHTGELTGYDVDVARAVGEKLG---RPVEFVEIPWDAIF
*: * * :: :. . : .
Mvan_4703|M.vanbaalenii_PYR-1 QAVQANQAAGVIAGMSITDERKAVFDFSDPYFESGVQMAVLDSNDTIASY
MSMEG_5318|M.smegmatis_MC2_155 QAVQANQADGVIAGMSITDERKKVFDFSDPYFESGVQMAVLASDDDIKSY
Mflv_3164|M.gilvum_PYR-GCK QAVQANQVDGVIAGMSITEERKKVFDFSEPYFESGIQMAVLEDNEDITSY
MMAR_0061|M.marinum_M AQVAARRFDVGSASVKLTEARRRTVAFTN-GYDFGYYSLVVPPGSAITKF
MAV_0059|M.avium_104 AQVASRRFDVGSSSIKATDERRQTVAFTN-GYDFGYYALVVPPGSAIKEF
TH_0515|M.thermoresistible__bu AQVASGRFDVGSSSITTTEQRRRTVEFTN-GYDFGYFSLVVPSGSAITGF
Mb0419c|M.bovis_AF2122/97 TALQKSQVDIVVKTMSITCERRKLVNFSTVYLDAN-QRILAPRDSPITKV
Rv0411c|M.tuberculosis_H37Rv TALQKSQVDIVVKTMSITCERRKLVNFSTVYLDAN-QRILAPRDSPITKV
MUL_2809|M.ulcerans_Agy99 TALQSSQVDVVVKTMTITCERRKLVNFSTVYLDAN-QRILTSRDSPIFKV
MLBr_00303|M.leprae_Br4923 TALQKSEVDIIVKTMTITCKRRKLVNFSTVYLDAK-QRILAPRDSPITKP
MAB_0277c|M.abscessus_ATCC_199 AGLDAERFDVVANQVTITPARKAKYDISTPYAVGEGVIVTRADDNSIHSL
: . :. * *: :: .. *
Mvan_4703|M.vanbaalenii_PYR-1 EDLR-GQRVAVKNGTEGAEFAESIKDKYGFQIVSFADSASMFEEVKTGNS
MSMEG_5318|M.smegmatis_MC2_155 EDLR-GKRVAVKNGTEGAEFAESIKDKYGFTTVYFADSASMFDEVRTGNS
Mflv_3164|M.gilvum_PYR-GCK EDLR-GQRVSVKNGTQGSDFANSIKDQYGFEVVSFADSSTMFDEVKTGNS
MMAR_0061|M.marinum_M SDLAPGQRIGVVQGT---VEESYVVNSLHLQPVKYPDFATVYGNLKTHQI
MAV_0059|M.avium_104 TDLAAGQRIGVVQGT---VEESYVVDTLHLQPVKYPDFATVYASLKTRQI
TH_0515|M.thermoresistible__bu GDLVPGQRIGVVQGT---VQESYVVDTLGLRPVIFPDYNTVYASLKTRQI
Mb0419c|M.bovis_AF2122/97 SDLS-GKRVCVARGTTSLRRIREIAPPP--VIVSVVNWADCLVALQQREI
Rv0411c|M.tuberculosis_H37Rv SDLS-GKRVCVARGTTSLRRIREIAPPP--VIVSVVNWADCLVALQQREI
MUL_2809|M.ulcerans_Agy99 SDLS-GKRVCVARGTTSLRRIREIAPPP--VIVSVVNWADCLVALQQREI
MLBr_00303|M.leprae_Br4923 SDLS-NKRVCMTRGTTSLHQVSEVVPPP--IIVSAENWADCLVAMQQREI
MAB_0277c|M.abscessus_ATCC_199 SDVR--GKVAAENAT---SNWSQIARDAGARVEAVEGFTQSITLLSQGRV
*: :: ..* : . : .
Mvan_4703|M.vanbaalenii_PYR-1 VAVFEDYPVLLYGIQQGNGFKTVTPKEQGSNYGFAVNKGRNAELLTKFNE
MSMEG_5318|M.smegmatis_MC2_155 QAVFEDYPVLQYGIAQGNGFKTVTPKEKGANYGFAVNKGQNAELLQKFNA
Mflv_3164|M.gilvum_PYR-GCK VAVFEDYPVLLYGIAQGNGFKTVTPKEDPTGYGFAVNKGQNAELLQKFND
MMAR_0061|M.marinum_M DAWVAPGNQAEAAIRPGDPAVLVANTFGAGDFVAYVVARDNRPLLDALNS
MAV_0059|M.avium_104 DAWVAPAGQAATTIQPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNS
TH_0515|M.thermoresistible__bu DAWVAPSQQAEGTVRPGDPAEIIENTFSLDNFIAYAVAPGNQPLIDALNA
Mb0419c|M.bovis_AF2122/97 DAVSTDDTILAGLVEEDPYLHIVGPDMADQPYGVGIN-LDNTGLVRFVNG
Rv0411c|M.tuberculosis_H37Rv DAVSTDDTILAGLVEEDPYLHIVGPDMADQPYGVGIN-LDNTGLVRFVNG
MUL_2809|M.ulcerans_Agy99 DAVSTDDTILAGLVEEDPYLHIVGPNMANQPYGIGIN-LDNTGLVRFVNG
MLBr_00303|M.leprae_Br4923 DAISTDDAILAGLVEEDPYLHIVGPNMATQPYGIGIN-LNNTTLVRFVNG
MAB_0277c|M.abscessus_ATCC_199 DVVINDSIAVYAYLASTGDPAVKIAGATGQRSEQGFAARKNSGLLPDLDK
. : * *: .:
Mvan_4703|M.vanbaalenii_PYR-1 GLKNLKESGRYDAIIESYLG------------------------------
MSMEG_5318|M.smegmatis_MC2_155 GLAQLKESGRYDEIISTYLG------------------------------
Mflv_3164|M.gilvum_PYR-GCK GLENLKAQGRYDEILQTYLG------------------------------
MMAR_0061|M.marinum_M GLDAVIADGTWSQLYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAA--
MAV_0059|M.avium_104 GLDAVIADGTWSNLYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAAS--
TH_0515|M.thermoresistible__bu GLDAVIADGTWARLYSEWVPRALPPGWKPGSKAAPPPQLPDFDAIAAERA
Mb0419c|M.bovis_AF2122/97 TLERIRNDGTWNTLYRKWLT------------------------------
Rv0411c|M.tuberculosis_H37Rv TLERIRNDGTWNTLYRKWLT------------------------------
MUL_2809|M.ulcerans_Agy99 TLERIRNDGTWNTLYRKWLS------------------------------
MLBr_00303|M.leprae_Br4923 TLERIRRDGTWITLYRKWLT------------------------------
MAB_0277c|M.abscessus_ATCC_199 ALDQLAADGTLTRISQKYLKTDASG-------------------------
* : .* : ::
Mvan_4703|M.vanbaalenii_PYR-1 ------------EEAAETDNSFFG---LLKSTFPILMEGLRLTLILTVVS
MSMEG_5318|M.smegmatis_MC2_155 ------------EEAVDNDNSFLG---LLKSTFPILMIGLRMTLILTVVS
Mflv_3164|M.gilvum_PYR-GCK ------------EEAAESDDSLFG---LIKSTSPMLLAGLKMTIILTVVS
MMAR_0061|M.marinum_M HRHKPVGPAAPKSALTQLRDSFFDWDMYRQAIPTLFKTGLPNTLILTLSA
MAV_0059|M.avium_104 QHHKAVGPAAPKSTLAQLRDSFFDWDMYRQAIPTLLRTGLPNTLILTFSA
TH_0515|M.thermoresistible__bu SQQPAAGPGVRKSTLAQLADSFLDWELYRQAIPDLLTTGLPNTLLLTVGA
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 -------TTKPQAGKGDSGSTRSDTQLVLDNLWPMARAMITVTLPLTAIS
Mvan_4703|M.vanbaalenii_PYR-1 IAIALVLGVMFGLFRVSRSIWLRAIGTTYVDIFRGTPLLVQAFFIYFGVP
MSMEG_5318|M.smegmatis_MC2_155 IAIALVLGVIFGLLRVSRSVVLRAIGTTYVDIFRGTPLLVQAFFIYFGIP
Mflv_3164|M.gilvum_PYR-GCK IFFALILGVIFGLARVSRSIWLRAIGTTFVDIFRGTPLLVQAFFIYFGIP
MMAR_0061|M.marinum_M SIIGLALGMALAIAGISHQRWLRWPARVYTDIFRGLPEVVIILIIGLGVG
MAV_0059|M.avium_104 SVIGLVLGMVLAVAGISHARWLRWPARVYTDVFRGLPEVVIILLIGLGIG
TH_0515|M.thermoresistible__bu GVIGLVLGMVLAIAGISRSRLLRWPARVYTDIFRGLPEVVIILLIGLGLG
Mb0419c|M.bovis_AF2122/97 ---------VLGPAPAP-------PTPRYVD-------------------
Rv0411c|M.tuberculosis_H37Rv ---------VLGPAPAP-------PTPRYVD-------------------
MUL_2809|M.ulcerans_Agy99 ---------VLGPAPAP-------PRPRYVD-------------------
MLBr_00303|M.leprae_Br4923 ---------VLGPAPAP-------PTPRYVD-------------------
MAB_0277c|M.abscessus_ATCC_199 FVIGLVIALGVALARMSGHRVVTGLARIYISVIRGTPLLLQLFLIFFALP
.. . : .
Mvan_4703|M.vanbaalenii_PYR-1 SALD--FRMTALTAGIITLSLNAGAYMTEIVRGGIQSVDKGQMEAARSLG
MSMEG_5318|M.smegmatis_MC2_155 SALG--FQMSALTAGIITLSLNAGAYMTEIVRGGIQSVDKGQMEAARSLG
Mflv_3164|M.gilvum_PYR-GCK ATMG--FQMSAVTAGIITLSLNAGAYMTEIVRGGILSVDKGQMEAARSLG
MMAR_0061|M.marinum_M PIVGGLTNNNPYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLEASRALG
MAV_0059|M.avium_104 PIVGGLTNNNPYPLGIAALGMMAAAYIGEILRSGIQSVDPGQLEASRALG
TH_0515|M.thermoresistible__bu PVVGGLTGYNPFPLGILALGLMAAAYVGEILRSGIQSVEPGQLEAARALG
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 ---EFGVKISPFPAAVIAFSLNVGGYAAEIIRSSILSIPRGQWEAASSLG
Mvan_4703|M.vanbaalenii_PYR-1 IGYLPTMRKVILPQAIRTMIPSYVNQFVITLKDTSILSVIG----IAELT
MSMEG_5318|M.smegmatis_MC2_155 IGYLPTMRKVILPQAIRTMIPSYINQFVITLKDTSILSVIG----IAELT
Mflv_3164|M.gilvum_PYR-GCK IGYLPTMRKVILPQAIRTMIPSYINQFVITLKDTSILSVLG----IAELT
MMAR_0061|M.marinum_M FSYSAAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLIAQQRELF
MAV_0059|M.avium_104 FSYATAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLVADQRELF
TH_0515|M.thermoresistible__bu FSYPAAMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFLGLVADQRELF
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 MSYSTTLWRIVIPQASRVAVPPLSNTLISLVKDTSLASAIL----VTDVM
Mvan_4703|M.vanbaalenii_PYR-1 QTGRLIIARNYQSFTMWLIIGVIYFIVIMALTKLSDRLERRLVK------
MSMEG_5318|M.smegmatis_MC2_155 QTGRIIIARNFQSFTMWLIIGIIYFVVIMALTKLSDRVEKRLVK------
Mflv_3164|M.gilvum_PYR-GCK QSGRIIIAGNYKAFEMWLIVGVIYFIVIMALTKLSDRLERRLVK------
MMAR_0061|M.marinum_M QVGRDLNAQTGN-LSPLVAAGIFYLMLTVPLTHLVNYIDARLRRGRRRLD
MAV_0059|M.avium_104 QVGRDLNAETGN-LSPLVAAGACYLILTVPLTHLVNMIDARLRRGRAAVD
TH_0515|M.thermoresistible__bu QVGRDLNAQTGS-LSPLVAAGLFYLALTIPLTHLVNYVDNRLRRGRK-PA
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 RTAQVAAAPTFQFFTLYVTAGVYYWIVCMAMSAVQDRLEQRLEKSVAR--
Mvan_4703|M.vanbaalenii_PYR-1 -----------------
MSMEG_5318|M.smegmatis_MC2_155 -----------------
Mflv_3164|M.gilvum_PYR-GCK -----------------
MMAR_0061|M.marinum_M PEDPPGVVSSTIGEEMT
MAV_0059|M.avium_104 PEEPAEMLT--FGQEIT
TH_0515|M.thermoresistible__bu AEDPLEPAT---AQEMI
Mb0419c|M.bovis_AF2122/97 -----------------
Rv0411c|M.tuberculosis_H37Rv -----------------
MUL_2809|M.ulcerans_Agy99 -----------------
MLBr_00303|M.leprae_Br4923 -----------------
MAB_0277c|M.abscessus_ATCC_199 -----------------