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TRPPATQPPQRTTFPGISSRAWEHPADRTALTALRRLKGFDQVLKVLSGMLRERQHRLLYLASSARVGPR QFADLDELLDDCARVLDAPSRPEMFVTQSPVANAYTIGMDEPFIVITSGMYDLMSHDEMRFVIGHELGHA LSGHAVYRTMLMHLMRIASTFGFVPIGGWALRAIVAALMEWERKSELSGDRAGLLCGQDLDTAIRVELKL AAGARLDKLDSQAFLAQAREYERAGDMRDGLLKLLNLELKTHPFSVLRAAALTQWVDTGGYGAVMAGDYP RREDDDKAALRDDIGEAARHYRDGFDQSDDPLIRGIRDGLGGIVDGVGQAATSAADSVGRKISEWRRSAQ RDARRDDRRDGPEPDSGSDDAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3476 | - | - | 100% (373) | peptidase, M48 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1977 | - | 1e-161 | 76.92% (351) | hypothetical protein Rv1977 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2955 | - | 1e-111 | 62.79% (301) | hypothetical protein MAB_2955 |
| M. marinum M | MMAR_2906 | - | 1e-167 | 80.80% (349) | hypothetical protein MMAR_2906 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3147 | - | 4e-08 | 27.47% (233) | hypothetical protein MUL_3147 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1977|M.tuberculosis_H37Rv MSQTPATT---RKTFPEISSRAWEHPADRTALSALRRLKGFDQILKLMSG
MMAR_2906|M.marinum_M MSQTPATT---RTAFGGISSRAWEHPADRTALSALRRLKGFDQILKLLSG
MSMEG_3476|M.smegmatis_MC2_155 MTRPPATQPPQRTTFPGISSRAWEHPADRTALTALRRLKGFDQVLKVLSG
MAB_2955|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3147|M.ulcerans_Agy99 MAIVESPP---GHPYPHLPASFYGTPSGSPPGPTGYLEHPRRHPWEIGLL
Rv1977|M.tuberculosis_H37Rv MLRERQHRLLYLASAARVGPRQFADLDALLDECVDVLDASA--KPELYVM
MMAR_2906|M.marinum_M MLRERQHRLLYLASAARVGPRQFADLDALLDECVDVLDAPT--KPEVYVT
MSMEG_3476|M.smegmatis_MC2_155 MLRERQHRLLYLASSARVGPRQFADLDELLDDCARVLDAPS--RPEMFVT
MAB_2955|M.abscessus_ATCC_1997 ---------MYLATAIRADDRQFSTLNNTLHDCARILDAPE--IPELYVI
MUL_3147|M.ulcerans_Agy99 VLVIVSSVLLYLVAAAVVLSGKSSLLWISIVATPIVLFALRGLTYGKQRA
:**.:: . : : * : :* *
Rv1977|M.tuberculosis_H37Rv QSPIADAFTIGMGKPFTVITSGLYDLVTHDEMRFVMGHELGHALSGHAVY
MMAR_2906|M.marinum_M QSPMVNAYTIGMDAPFIVITSGLYDLMTHDELRFVVGHELGHALSGHATY
MSMEG_3476|M.smegmatis_MC2_155 QSPVANAYTIGMDEPFIVITSGMYDLMSHDEMRFVIGHELGHALSGHAVY
MAB_2955|M.abscessus_ATCC_1997 QGPYANAYTIGMDRPFIVLTSGLLDLMNEQELRFIVGHELGHALSGHAVY
MUL_3147|M.ulcerans_Agy99 NGVKMSPTQFAEGYWLVVEAARRFGLSEVPDAYVVLGNGLINAFSSGHGF
:. .. :. . : * :: .* : .::*: * :*:*. :
Rv1977|M.tuberculosis_H37Rv RTMMMHLLRLARSFGVLPVGGWALRAIVAALLEWQRKSELSGDRAGLLCA
MMAR_2906|M.marinum_M RTMLMHLMRLAGSLGFLPIGGWALRAIVAALLEWQRKSELSGDRAGLLCC
MSMEG_3476|M.smegmatis_MC2_155 RTMLMHLMRIASTFGFVPIGGWALRAIVAALMEWERKSELSGDRAGLLCG
MAB_2955|M.abscessus_ATCC_1997 RTMLLHLMRLAGNLGWMPIGGWALRAIVAALMEWQRKSELSGDRAGMLCG
MUL_3147|M.ulcerans_Agy99 RRYVVVYS------DLFEIRGQARDPEALAFIIGHEVGHLAAGHASYWR-
* :: . . : * * . . *:: .. ..*:..:*.
Rv1977|M.tuberculosis_H37Rv QDLDTALRVEMKLAGGCRLDKLDSEAF---LAQAREYETSGDMRDGVLKL
MMAR_2906|M.marinum_M QDLDTAIRVEMKLAGGSRLDKLDSEAF---LAQAAEYERSGDMRDGLLKL
MSMEG_3476|M.smegmatis_MC2_155 QDLDTAIRVELKLAAGARLDKLDSQAF---LAQAREYERAGDMRDGLLKL
MAB_2955|M.abscessus_ATCC_1997 QDVDTAIRVEMKLAGGSRLDEMDTQRF---LAQAAEYERTGDMRDGVLKL
MUL_3147|M.ulcerans_Agy99 QLMQLAMRVPLLGPTLSRSMEYTADNYGYAFRPAGARKAIGVLSAGKYLL
* :: *:** : . .* : :: : : * : * : * *
Rv1977|M.tuberculosis_H37Rv LNLELQTHPFSVLRAAALTHWVDTGGYAKVIAGEYPRRADDGNAKFADDL
MMAR_2906|M.marinum_M LNLELQTHPFSVLRVAELTKWVDAGGYGKVMSGSYPLRLDDGQSSIADDL
MSMEG_3476|M.smegmatis_MC2_155 LNLELKTHPFSVLRAAALTQWVDTGGYGAVMAGDYPRREDDDKAALRDDI
MAB_2955|M.abscessus_ATCC_1997 LNLELQSHPFSVIRAAELSKWIDRGEYGAILSGDYPLRTDDEQTDLGSEF
MUL_3147|M.ulcerans_Agy99 RSVDFDGMADRAGSETGFFVWLAN------MVSSHPVNTWR-AAALRNRM
.:::. . . : : *: : ..:* . : : . :
Rv1977|M.tuberculosis_H37Rv GAAARYYRDGFDQSNDPLIKGIR---DGFGGIVEGVGRAASNAADSLGRK
MMAR_2906|M.marinum_M GEAARHYKDGFDQSDDPLIKGIR---DGLGGIVDGVGRAATSAADSLGRK
MSMEG_3476|M.smegmatis_MC2_155 GEAARHYRDGFDQSDDPLIRGIR---DGLGGIVDGVGQAATSAADSVGRK
MAB_2955|M.abscessus_ATCC_1997 RSAARSYKENFDSSTAPLISALRNFGSTLDGVVNVVGQGVTDVATDVRRR
MUL_3147|M.ulcerans_Agy99 VAGSLFFRLKQPALVPPTAWAVP----GDGGWAR----------------
.: :: * .: .* .
Rv1977|M.tuberculosis_H37Rv ITEWRQPSK----------------------
MMAR_2906|M.marinum_M INEWRHNPK----------------------
MSMEG_3476|M.smegmatis_MC2_155 ISEWRRSAQRDARRDDRRDGPEPDSGSDDAG
MAB_2955|M.abscessus_ATCC_1997 FSEWRNNSDDEPDDDT---------------
MUL_3147|M.ulcerans_Agy99 -------------------------------