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MYLATAIRADDRQFSTLNNTLHDCARILDAPEIPELYVIQGPYANAYTIGMDRPFIVLTSGLLDLMNEQE LRFIVGHELGHALSGHAVYRTMLLHLMRLAGNLGWMPIGGWALRAIVAALMEWQRKSELSGDRAGMLCGQ DVDTAIRVEMKLAGGSRLDEMDTQRFLAQAAEYERTGDMRDGVLKLLNLELQSHPFSVIRAAELSKWIDR GEYGAILSGDYPLRTDDEQTDLGSEFRSAARSYKENFDSSTAPLISALRNFGSTLDGVVNVVGQGVTDVA TDVRRRFSEWRNNSDDEPDDDT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2955 | - | - | 100% (302) | hypothetical protein MAB_2955 |
| M. abscessus ATCC 19977 | MAB_1573c | - | 4e-06 | 36.99% (73) | hypothetical protein MAB_1573c |
| M. abscessus ATCC 19977 | MAB_3927c | - | 3e-05 | 39.22% (51) | protease HtpX-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0578 | htpX | 2e-05 | 23.84% (172) | heat shock protein HtpX |
| M. gilvum PYR-GCK | Mflv_5252 | - | 5e-05 | 37.25% (51) | heat shock protein HtpX |
| M. tuberculosis H37Rv | Rv1977 | - | 1e-101 | 59.32% (295) | hypothetical protein Rv1977 |
| M. leprae Br4923 | MLBr_02278 | htpX | 1e-05 | 37.25% (51) | heat shock protein HtpX |
| M. marinum M | MMAR_2906 | - | 1e-113 | 66.21% (293) | hypothetical protein MMAR_2906 |
| M. avium 104 | MAV_4580 | - | 6e-05 | 24.28% (173) | heat shock protein HtpX |
| M. smegmatis MC2 155 | MSMEG_3476 | - | 1e-111 | 63.25% (302) | peptidase, M48 family protein |
| M. thermoresistible (build 8) | TH_1766 | htpX | 2e-06 | 25.82% (213) | PROBABLE PROTEASE TRANSMEMBRANE PROTEIN HEAT SHOCK PROTEIN |
| M. ulcerans Agy99 | MUL_3147 | - | 1e-07 | 30.84% (107) | hypothetical protein MUL_3147 |
| M. vanbaalenii PYR-1 | Mvan_0993 | - | 6e-05 | 37.25% (51) | heat shock protein HtpX |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5252|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0993|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1766|M.thermoresistible__bu --------------------------------------------------
MLBr_02278|M.leprae_Br4923 --------------------------------------------------
MAV_4580|M.avium_104 --------------------------------------------------
Mb0578|M.bovis_AF2122/97 --------------------------------------------------
Rv1977|M.tuberculosis_H37Rv MSQTPATT---RKTFPEISSRAWEHPADRTALSALRRLKGFDQILKLMSG
MMAR_2906|M.marinum_M MSQTPATT---RTAFGGISSRAWEHPADRTALSALRRLKGFDQILKLLSG
MSMEG_3476|M.smegmatis_MC2_155 MTRPPATQPPQRTTFPGISSRAWEHPADRTALTALRRLKGFDQVLKVLSG
MAB_2955|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3147|M.ulcerans_Agy99 -----------------------------------------------MAI
Mflv_5252|M.gilvum_PYR-GCK --------MTWHPHANRAKTFLLLAVFSGLIVAVGAMFG-RNIMFLAVLF
Mvan_0993|M.vanbaalenii_PYR-1 --------MTWHPHANRAKTFLLLVLFSGLIVGVGALFG-RNIMFLAVLF
TH_1766|M.thermoresistible__bu --------MTWNPHANRLKTFVLLVGMSALIVFIGALFQNRSILFLAVLF
MLBr_02278|M.leprae_Br4923 --------MTWHPQANRLKTFVLLVGMSTLIVVVGAIFG-RTALFFATLV
MAV_4580|M.avium_104 --------MTWHPHANRFKTFALLVGMSALIVFVGSLFG-RTAMFFAVLF
Mb0578|M.bovis_AF2122/97 --------MTWHPHANRLKTFLLLVGMSALIVAVGALFG-RTALMLAALF
Rv1977|M.tuberculosis_H37Rv MLRERQHRLLYLASAARVGPRQFADLDALLDECVDVLDASAKPELYVMQS
MMAR_2906|M.marinum_M MLRERQHRLLYLASAARVGPRQFADLDALLDECVDVLDAPTKPEVYVTQS
MSMEG_3476|M.smegmatis_MC2_155 MLRERQHRLLYLASSARVGPRQFADLDELLDDCARVLDAPSRPEMFVTQS
MAB_2955|M.abscessus_ATCC_1997 ---------MYLATAIRADDRQFSTLNNTLHDCARILDAPEIPELYVIQG
MUL_3147|M.ulcerans_Agy99 VESPPGHPYPHLPASFYGTPSGSPPGPTGYLEHP----RRHPWEIGLLVL
. : .
Mflv_5252|M.gilvum_PYR-GCK ALGMNAYVYFNSDKLALRAMHAQPVNEMQAPVMYKIVRELATTARQPMPR
Mvan_0993|M.vanbaalenii_PYR-1 AIGMNAYVYFNSDKLALRAMHAQPVNEMQAPVMYKIVRELATTARQPMPR
TH_1766|M.thermoresistible__bu AVGMNVYVYFNSDKLALRAMHAQPVTELQAPVMYRIVRELANTAHQPMPR
MLBr_02278|M.leprae_Br4923 AVGINVYTYYNSDKLALRAMHAQPVSEVQAPVMYRIVRELATGAHQPMPR
MAV_4580|M.avium_104 AIGMNVYTYYNSDKLALRAMHAQPVSELQAPAMYRIVRELATAAHQPMPR
Mb0578|M.bovis_AF2122/97 AVGMNVYVYFNSDKLALRAMHAQPVSELQAPAMYRIVRELATSAHQPMPR
Rv1977|M.tuberculosis_H37Rv PIADAFTIGMGKPFTVITSGLYDLVTHDEMRFVMGHELGHALSGHAVYRT
MMAR_2906|M.marinum_M PMVNAYTIGMDAPFIVITSGLYDLMTHDELRFVVGHELGHALSGHATYRT
MSMEG_3476|M.smegmatis_MC2_155 PVANAYTIGMDEPFIVITSGMYDLMSHDEMRFVIGHELGHALSGHAVYRT
MAB_2955|M.abscessus_ATCC_1997 PYANAYTIGMDRPFIVLTSGLLDLMNEQELRFIVGHELGHALSGHAVYRT
MUL_3147|M.ulcerans_Agy99 VIVSSVLLYLVAAAVVLSGKSSLLWISIVATPIVLFALRGLTYGKQRANG
.: . : .:
Mflv_5252|M.gilvum_PYR-GCK LYISDTAAPNAFATGRNPRNSAVCCTTGILQMLNERELRAVLGHELSHVY
Mvan_0993|M.vanbaalenii_PYR-1 LYISDTAAPNAFATGRNPRNAAVCCTTGILQMLNERELRAVLGHELSHVY
TH_1766|M.thermoresistible__bu LYISDTANPNAFATGRNPRNAAVCCTTGLLQILNERELRAVLGHELSHVY
MLBr_02278|M.leprae_Br4923 LYISDTNAPNAFATGRNPRNAAVCCTTGILEILNERELRAVLGHELSHVY
MAV_4580|M.avium_104 LYISDTNAPNAFATGRNPRNAAVCCTTGILGILNERELRAVLGHELSHVY
Mb0578|M.bovis_AF2122/97 LYISDTAAPNAFATGRNPRNAAVCCTTGILRILNERELRAVLGHELSHVY
Rv1977|M.tuberculosis_H37Rv MMMHLLRLARSFGVLPVGGWALRAIVAALLEWQRKSELSGDRAGLLCAQD
MMAR_2906|M.marinum_M MLMHLMRLAGSLGFLPIGGWALRAIVAALLEWQRKSELSGDRAGLLCCQD
MSMEG_3476|M.smegmatis_MC2_155 MLMHLMRIASTFGFVPIGGWALRAIVAALMEWERKSELSGDRAGLLCGQD
MAB_2955|M.abscessus_ATCC_1997 MLLHLMRLAGNLGWMPIGGWALRAIVAALMEWQRKSELSGDRAGMLCGQD
MUL_3147|M.ulcerans_Agy99 VKMSPTQFAEGYWLVVEAARRFGLSEVPDAYVVLGNGLIN--AFSSGHGF
: : . . * .
Mflv_5252|M.gilvum_PYR-GCK NRDILISCVAGAMASVITALANLAFFASMFGGNRDGGTNPFAILLVSLLG
Mvan_0993|M.vanbaalenii_PYR-1 NRDILISCVAGAMASVITALANLAFFASMFGGNRDGGTNPLAILLVSLLG
TH_1766|M.thermoresistible__bu NRDILISCVAGALAAIVTALANIAMYASMFGGNRQGGPSPFALLLVSFLG
MLBr_02278|M.leprae_Br4923 NRDILISCVAGALAGVITALANMAMWAGTFG-TTRDEENPFALLLVSLLG
MAV_4580|M.avium_104 NRDILISCIAGAMASVITALANMAMFAGMFGGNDRDGENPFALLLVSLLG
Mb0578|M.bovis_AF2122/97 NRDILISCVAGALAAVITALANMAMWAGMFG-GNRDNANPFALLLVALLG
Rv1977|M.tuberculosis_H37Rv LDTALRVEMKLAGGCRLDKLDSEAFLAQAREYETSGDMRDGVLKLLNLEL
MMAR_2906|M.marinum_M LDTAIRVEMKLAGGSRLDKLDSEAFLAQAAEYERSGDMRDGLLKLLNLEL
MSMEG_3476|M.smegmatis_MC2_155 LDTAIRVELKLAAGARLDKLDSQAFLAQAREYERAGDMRDGLLKLLNLEL
MAB_2955|M.abscessus_ATCC_1997 VDTAIRVEMKLAGGSRLDEMDTQRFLAQAAEYERTGDMRDGVLKLLNLEL
MUL_3147|M.ulcerans_Agy99 RRYVVVYSDLFEIRGQARDPEALAFIIGHEVGHLAAGHASYWRQLMQLAM
: : *: :
Mflv_5252|M.gilvum_PYR-GCK PIAATVIRLAVSRSREYQADQSGAELTGD--PLALASALRKISSGVERAP
Mvan_0993|M.vanbaalenii_PYR-1 PIAATVIRLAVSRSREYQADQSGAELTGD--PLALASALRKISAGVERAP
TH_1766|M.thermoresistible__bu PIAATVIRMAVSRSREYQADQSGAELTGD--PLALASALRKISGGVQAAP
MLBr_02278|M.leprae_Br4923 PIAATVVRLAVSRSREYQADESGAMLTGD--PLALASALRKISSGVQAAP
MAV_4580|M.avium_104 PIAATVVRLAVSRSREYQADESGAVLTGD--PLALASALRKISGGVQAAP
Mb0578|M.bovis_AF2122/97 PIAATVIRMAVSRSREYQADESGAVLTGD--PLALASALRKISGGVQAAP
Rv1977|M.tuberculosis_H37Rv QTHPFSVLRAAALTHWVDTGGYAKVIAGEY-PRRADDGNAKFADDLGAAA
MMAR_2906|M.marinum_M QTHPFSVLRVAELTKWVDAGGYGKVMSGSY-PLRLDDGQSSIADDLGEAA
MSMEG_3476|M.smegmatis_MC2_155 KTHPFSVLRAAALTQWVDTGGYGAVMAGDY-PRREDDDKAALRDDIGEAA
MAB_2955|M.abscessus_ATCC_1997 QSHPFSVIRAAELSKWIDRGEYGAILSGDY-PLRTDDEQTDLGSEFRSAA
MUL_3147|M.ulcerans_Agy99 RVPLLGPTLSRSMEYTADNYGYAFRPAGARKAIGVLSAGKYLLRSVDFDG
: . :* . . : .
Mflv_5252|M.gilvum_PYR-GCK LPPEPQLADQAHLMIANPFR----AGEKIGKLFATHPPMADRIARLEAMA
Mvan_0993|M.vanbaalenii_PYR-1 LPPEPQLADQAHLMIANPFR----SGEKIGKLFATHPPIADRIARLEAMA
TH_1766|M.thermoresistible__bu LPPEPQLADQAHLMIASPFR----AGEKIGKLFSTHPPIEDRIARLEAMA
MLBr_02278|M.leprae_Br4923 LPPEPQLASQAHLMIANPFR----VGDRIGSLFSTHPPIEDRIRRLETMV
MAV_4580|M.avium_104 LPPEPQLASQAHLMIANPFR----AGERIGSLFSTHPPIEDRIRRLESMA
Mb0578|M.bovis_AF2122/97 LPPEPQLASQAHLMIANPFR----AGERIGSLFSTHPPIEDRIRRLEAMA
Rv1977|M.tuberculosis_H37Rv RYYRDGFDQSNDPLIKGIR---DGFGGIVEGVGRAASNAADSLGRKITEW
MMAR_2906|M.marinum_M RHYKDGFDQSDDPLIKGIR---DGLGGIVDGVGRAATSAADSLGRKINEW
MSMEG_3476|M.smegmatis_MC2_155 RHYRDGFDQSDDPLIRGIR---DGLGGIVDGVGQAATSAADSVGRKISEW
MAB_2955|M.abscessus_ATCC_1997 RSYKENFDSSTAPLISALRNFGSTLDGVVNVVGQGVTDVATDVRRRFSEW
MUL_3147|M.ulcerans_Agy99 MADRAGSETGFFVWLANMVSSHPVNTWRAAALRNRMVAGSLFFRLKQPAL
. : : .
Mflv_5252|M.gilvum_PYR-GCK G----RGPGQY----------------
Mvan_0993|M.vanbaalenii_PYR-1 GPDTYRHPGLY----------------
TH_1766|M.thermoresistible__bu G----RGPGHYY---------------
MLBr_02278|M.leprae_Br4923 AGR------------------------
MAV_4580|M.avium_104 G-R------------------------
Mb0578|M.bovis_AF2122/97 RG-------------------------
Rv1977|M.tuberculosis_H37Rv RQPSK----------------------
MMAR_2906|M.marinum_M RHNPK----------------------
MSMEG_3476|M.smegmatis_MC2_155 RRSAQRDARRDDRRDGPEPDSGSDDAG
MAB_2955|M.abscessus_ATCC_1997 RNNSDDEPDDDT---------------
MUL_3147|M.ulcerans_Agy99 VPPTAWAVPGDGGWAR-----------