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VRLRQATIFCAALLSLSTLAAGCTSGPTPDPSPLRHITESKTLRVCSTGDYRPFTFRDPQGTWSGMDIDL ADDMARRLGVEIDMVQTTWANLVGDLNDRCDIAMGGISITLKRAQEAVYSAPYLRDGKAAIVRCADASRF RSLQDIDRPGTRVVVNPGGTNEEFAKGNLKQATIIDHPDNNTIFGEISAGHADAMITDASEIRFQTAQDR TLCGVSTDRPFTFEQKAYLLPAAAIDTARWVDEWLNIVQHDGTYDRISQKWLGRVVGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3442 | - | - | 100% (268) | cyclohexadienyl dehydratase |
| M. smegmatis MC2 155 | MSMEG_1612 | - | 2e-14 | 26.39% (269) | extracellular solute-binding protein, family protein 3 |
| M. smegmatis MC2 155 | MSMEG_6307 | - | 3e-12 | 26.48% (253) | glutamine-binding periplasmic protein/glutamine transport |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0419c | glnH | 1e-05 | 25.68% (222) | glutamine-binding lipoprotein |
| M. gilvum PYR-GCK | Mflv_1232 | - | 2e-16 | 28.30% (265) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | Rv0411c | glnH | 1e-05 | 25.68% (222) | glutamine-binding lipoprotein |
| M. leprae Br4923 | MLBr_00303 | glnH | 4e-06 | 25.44% (228) | putative glutamine-binding protein |
| M. abscessus ATCC 19977 | MAB_0277c | - | 1e-13 | 26.22% (267) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0061 | glnQ | 1e-07 | 22.32% (224) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 4e-08 | 26.39% (216) | amino acid ABC transporter, permease protein, |
| M. thermoresistible (build 8) | TH_0515 | - | 2e-08 | 24.80% (254) | amino acid ABC transporter, permease protein, 3-TM region, |
| M. ulcerans Agy99 | MUL_2809 | glnH | 5e-06 | 24.02% (229) | glutamine-binding lipoprotein GlnH |
| M. vanbaalenii PYR-1 | Mvan_5576 | - | 2e-16 | 28.00% (275) | polar amino acid ABC transporter, inner membrane subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0419c|M.bovis_AF2122/97 -MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGME
Rv0411c|M.tuberculosis_H37Rv -MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGME
MUL_2809|M.ulcerans_Agy99 -MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLPLPTPVGME
MLBr_00303|M.leprae_Br4923 MMTRQFKIQRACS---VLATAMMLAACGHAELLTVASMPTLPPPTPVGME
Mflv_1232|M.gilvum_PYR-GCK -------------------------------MSRTLGRTRRACYGPPMGN
Mvan_5576|M.vanbaalenii_PYR-1 -------------------------------MSRTLQLTPPGCYGPAMRY
MAB_0277c|M.abscessus_ATCC_199 -------------------------------------------------M
MMAR_0061|M.marinum_M ---------------MLAVSATILIVLG--LALAAPALADHNQCAPAGVD
MAV_0059|M.avium_104 -----MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPK
TH_0515|M.thermoresistible__bu -------VTRAAVVAVIALLVGSLTAGG--TVLAAPAAATVDQCAPPGVQ
MSMEG_3442|M.smegmatis_MC2_155 ----------------------------------------------MRLR
Mb0419c|M.bovis_AF2122/97 IMPPQPPLPPDSSSQDCDPTASLRPFATKAEADAA-VADIRARGRLIVGL
Rv0411c|M.tuberculosis_H37Rv IMPPQPPLPPDSSSQDCDPTASLRPFATKAEADAA-VADIRARGRLIVGL
MUL_2809|M.ulcerans_Agy99 VMPPEPPLPADSSSQDCDPTASLRPFPTKAEADAA-VADIRARGRLIVGL
MLBr_00303|M.leprae_Br4923 QVPPELLLPQDNTEEDCDPTASLRPFPTKAEADAA-VAEIRARGRLIVGL
Mflv_1232|M.gilvum_PYR-GCK PRRVLLAVLAALAVLLTACGSSGPGNSVKDSGV-----LRVGTEGVYAPF
Mvan_5576|M.vanbaalenii_PYR-1 PRTVLLAVLAAIAVLLTACGSSGSGNPVESSGV-----LRVGTEGVYAPF
MAB_0277c|M.abscessus_ATCC_199 FRAIVLALLALVAVAGCAAPTQEP--------------LRVGTEGVYAPF
MMAR_0061|M.marinum_M SAMVLPADLSSATTAGSDEDVQTTAGVVPLSSVNI-GDLGLGTPGVLTAG
MAV_0059|M.avium_104 SAAVLPENLTRGGSMS-QPDEHTTPTVEPLSSVRI-DTLGLGTPGVLTVG
TH_0515|M.thermoresistible__bu SASPLPTNLAAAEAGP-GVDRYTTDGVVPLDNIDP-SALRLRVPGVLTVG
MSMEG_3442|M.smegmatis_MC2_155 QATIFCAALLSLSTLAAGCTSGPTPDPSPLRHITESKTLRVCSTGDYRPF
Mb0419c|M.bovis_AF2122/97 DIGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERV
Rv0411c|M.tuberculosis_H37Rv DIGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERV
MUL_2809|M.ulcerans_Agy99 DIGSNLFSFRDPITGEITGFDVDIASEVARDIFGGPTHVEYRILSAAERI
MLBr_00303|M.leprae_Br4923 EIGSNLFSFRDPITGEITGFDIDIAGEVARDIFGTPSHMEYRILSTAARI
Mflv_1232|M.gilvum_PYR-GCK SFHDP-------ATGQLTGYDVDVARAVGEKLG---VNVEFVETPWDSIF
Mvan_5576|M.vanbaalenii_PYR-1 SYHDP-------ATGQLTGYDVDVARAVGEKLG---VNVEFVETPWDSIF
MAB_0277c|M.abscessus_ATCC_199 SFHDG-------HTGELTGYDVDVARAVGEKLG---RPVEFVEIPWDAIF
MMAR_0061|M.marinum_M TLSDAPPNTCINSTGQFTGFDNELLRAIAAKLG---LQVRFVGTDFSGLL
MAV_0059|M.avium_104 TLSGAPPNVCITPTGQYSGFDNQLLRAIAGKLG---LQVRFVGTDFAGLL
TH_0515|M.thermoresistible__bu TLSDAPPSICINSLGEFTGFDNELLRAIAAKLG---LQISFVGTEFSALL
MSMEG_3442|M.smegmatis_MC2_155 TFRDP--------QGTWSGMDIDLADDMARRLG---VEIDMVQTTWANLV
. * :* * :: :. : : .
Mb0419c|M.bovis_AF2122/97 TALQKSQVDIVVKTMSITCERRKLVNFSTVYL-DANQRILAPRD-SPITK
Rv0411c|M.tuberculosis_H37Rv TALQKSQVDIVVKTMSITCERRKLVNFSTVYL-DANQRILAPRD-SPITK
MUL_2809|M.ulcerans_Agy99 TALQSSQVDVVVKTMTITCERRKLVNFSTVYL-DANQRILTSRD-SPIFK
MLBr_00303|M.leprae_Br4923 TALQKSEVDIIVKTMTITCKRRKLVNFSTVYL-DAKQRILAPRD-SPITK
Mflv_1232|M.gilvum_PYR-GCK AALEANRFDVVANQVTITPERQQKYDLSEPYS-IGEGVIVTRADDDSITS
Mvan_5576|M.vanbaalenii_PYR-1 AALEANRFDVVANQVTITPERQQKYDLSEPYS-IGEGVIVTRADDDSITS
MAB_0277c|M.abscessus_ATCC_199 AGLDAERFDVVANQVTITPARKAKYDISTPYA-VGEGVIVTRADDNSIHS
MMAR_0061|M.marinum_M AQVAARRFDVGSASVKLTEARRRTVAFTNGYD-FGYYSLVVPPG-SAITK
MAV_0059|M.avium_104 AQVASRRFDVGSSSIKATDERRQTVAFTNGYD-FGYYALVVPPG-SAIKE
TH_0515|M.thermoresistible__bu AQVASGRFDVGSSSITTTEQRRRTVEFTNGYD-FGYFSLVVPSG-SAITG
MSMEG_3442|M.smegmatis_MC2_155 GDLN-DRCDIAMGGISITLKRAQEAVYSAPYLRDGKAAIVRCADASRFRS
: . *: :. * * : * . :: . . :
Mb0419c|M.bovis_AF2122/97 VSDLS--GKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREI
Rv0411c|M.tuberculosis_H37Rv VSDLS--GKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREI
MUL_2809|M.ulcerans_Agy99 VSDLS--GKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREI
MLBr_00303|M.leprae_Br4923 PSDLS--NKRVCMTRGTTSLHQVSEVVPPPIIVSAENWADCLVAMQQREI
Mflv_1232|M.gilvum_PYR-GCK LDDLR---GRRAAQSTTSNWAQVARDAG-AQIESVEGLTQAMALLSQGRV
Mvan_5576|M.vanbaalenii_PYR-1 LADLR---GKRAAQSTTSNWAGVARDAG-AQIESVEGLTQAMALLSQGRV
MAB_0277c|M.abscessus_ATCC_199 LSDVR---GKVAAENATSNWSQIARDAG-ARVEAVEGFTQSITLLSQGRV
MMAR_0061|M.marinum_M FSDLAP-GQRIGVVQGTVEESYVVNSLH-LQPVKYPDFATVYGNLKTHQI
MAV_0059|M.avium_104 FTDLAA-GQRIGVVQGTVEESYVVDTLH-LQPVKYPDFATVYASLKTRQI
TH_0515|M.thermoresistible__bu FGDLVP-GQRIGVVQGTVQESYVVDTLG-LRPVIFPDYNTVYASLKTRQI
MSMEG_3442|M.smegmatis_MC2_155 LQDIDRPGTRVVVNPGGTNEEFAKGNLKQATIIDHPDNNTIFGEISAGHA
*: : . . :. .
Mb0419c|M.bovis_AF2122/97 DAVSTDDTILAGLVEE--DPYLHIVGPDMADQPYGVGINLDNTGLVRFVN
Rv0411c|M.tuberculosis_H37Rv DAVSTDDTILAGLVEE--DPYLHIVGPDMADQPYGVGINLDNTGLVRFVN
MUL_2809|M.ulcerans_Agy99 DAVSTDDTILAGLVEE--DPYLHIVGPNMANQPYGIGINLDNTGLVRFVN
MLBr_00303|M.leprae_Br4923 DAISTDDAILAGLVEE--DPYLHIVGPNMATQPYGIGINLNNTTLVRFVN
Mflv_1232|M.gilvum_PYR-GCK DVVVNDSLSIYAYLAETGDTAVKIAGTTGEKSEQGFAARK-NSGLLPDLN
Mvan_5576|M.vanbaalenii_PYR-1 DVVVNDSLSIYAYLAETNDTAVKIAGATGEKSEQGFAARK-NSGLLPDLN
MAB_0277c|M.abscessus_ATCC_199 DVVINDSIAVYAYLASTGDPAVKIAGATGQRSEQGFAARK-NSGLLPDLD
MMAR_0061|M.marinum_M DAWVAPGNQAEAAIRP-GDPAVLVANTFGAGDFVAYVVARDNRPLLDALN
MAV_0059|M.avium_104 DAWVAPAGQAATTIQP-GDPAVVVANTISPGNFVAYAVAKDNKPLVDALN
TH_0515|M.thermoresistible__bu DAWVAPSQQAEGTVRP-GDPAEIIENTFSLDNFIAYAVAPGNQPLIDALN
MSMEG_3442|M.smegmatis_MC2_155 DAMITDASEIRFQTAQDRTLCGVSTDRPFTFEQKAYLLPAAAIDTARWVD
*. . . . ::
Mb0419c|M.bovis_AF2122/97 GTLERIRNDGTWNTLYRKWLTVLGPAPAPPTPRYVD--------------
Rv0411c|M.tuberculosis_H37Rv GTLERIRNDGTWNTLYRKWLTVLGPAPAPPTPRYVD--------------
MUL_2809|M.ulcerans_Agy99 GTLERIRNDGTWNTLYRKWLSVLGPAPAPPRPRYVD--------------
MLBr_00303|M.leprae_Br4923 GTLERIRRDGTWITLYRKWLTVLGPAPAPPTPRYVD--------------
Mflv_1232|M.gilvum_PYR-GCK TAVEELKADGTMAEISQKYLKTNASGGQDTPQAQ----------------
Mvan_5576|M.vanbaalenii_PYR-1 TALEELKADGTLAEISQKYLKTNASGGQDAPQTQ----------------
MAB_0277c|M.abscessus_ATCC_199 KALDQLAADGTLTRISQKYLKTDASG-TTKPQAGKG--------------
MMAR_0061|M.marinum_M SGLDAVIADGTWSQLYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAA-
MAV_0059|M.avium_104 SGLDAVIADGTWSNLYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAAS-
TH_0515|M.thermoresistible__bu AGLDAVIADGTWARLYSEWVPRALPPGWKPGSKAAPPPQLPDFDAIAAER
MSMEG_3442|M.smegmatis_MC2_155 EWLNIVQHDGTYDRISQKWLGRVVGP------------------------
:: : *** : :::
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK -----------PRSTLQLVLDNLWP----------LAKAALTMTIPLTII
Mvan_5576|M.vanbaalenii_PYR-1 -----------PRSALRLVLDNLWP----------LARAALTMTIPLTII
MAB_0277c|M.abscessus_ATCC_199 -------DSGSTRSDTQLVLDNLWP----------MARAMITVTLPLTAI
MMAR_0061|M.marinum_M -HRHKPVGPAAPKSALTQLRDSFFDWDMYRQAIPTLFKTGLPNTLILTLS
MAV_0059|M.avium_104 -QHHKAVGPAAPKSTLAQLRDSFFDWDMYRQAIPTLLRTGLPNTLILTFS
TH_0515|M.thermoresistible__bu ASQQPAAGPGVRKSTLAQLADSFLDWELYRQAIPDLLTTGLPNTLLLTVG
MSMEG_3442|M.smegmatis_MC2_155 --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK SFVIGLVIALGVALARLSSNVVLSNLARFYISVIRGTPLLVQLFIVFFAL
Mvan_5576|M.vanbaalenii_PYR-1 SFVIGLVIALGVALARLSSNVVLTNLARFYISVIRGTPLLVQLFIVFFAL
MAB_0277c|M.abscessus_ATCC_199 SFVIGLVIALGVALARMSGHRVVTGLARIYISVIRGTPLLLQLFLIFFAL
MMAR_0061|M.marinum_M ASIIGLALGMALAIAGISHQRWLRWPARVYTDIFRGLPEVVIILIIGLGV
MAV_0059|M.avium_104 ASVIGLVLGMVLAVAGISHARWLRWPARVYTDVFRGLPEVVIILLIGLGI
TH_0515|M.thermoresistible__bu AGVIGLVLGMVLAIAGISRSRLLRWPARVYTDIFRGLPEVVIILLIGLGL
MSMEG_3442|M.smegmatis_MC2_155 --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK PEFG---VKIDPFPAAVIAFSLNVGGYAAEIIRSAIQSIPKGQWEAAETI
Mvan_5576|M.vanbaalenii_PYR-1 PEFG---VRIDPFPAAVIAFSLNVGGYAAEIIRSAIQSIPKGQWEAAETI
MAB_0277c|M.abscessus_ATCC_199 PEFG---VKISPFPAAVIAFSLNVGGYAAEIIRSSILSIPRGQWEAASSL
MMAR_0061|M.marinum_M GPIVGGLTNNNPYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLEASRAL
MAV_0059|M.avium_104 GPIVGGLTNNNPYPLGIAALGMMAAAYIGEILRSGIQSVDPGQLEASRAL
TH_0515|M.thermoresistible__bu GPVVGGLTGYNPFPLGILALGLMAAAYVGEILRSGIQSVEPGQLEAARAL
MSMEG_3442|M.smegmatis_MC2_155 --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK GLNYVGTLRRIILPQATRVAVPPLSNTLISLVKDTSLASTILVTELLR--
Mvan_5576|M.vanbaalenii_PYR-1 GLNYAGTLRRIILPQATRVAVPPLSNTLISLVKDTSLASTILVTELLR--
MAB_0277c|M.abscessus_ATCC_199 GMSYSTTLWRIVIPQASRVAVPPLSNTLISLVKDTSLASAILVTDVMR--
MMAR_0061|M.marinum_M GFSYSAAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLIAQQREL
MAV_0059|M.avium_104 GFSYATAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLVADQREL
TH_0515|M.thermoresistible__bu GFSYPAAMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFLGLVADQREL
MSMEG_3442|M.smegmatis_MC2_155 --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK -QAQIIAAPTFEFFALYGTAAVYYWVICLVLSFGQARFEHRLERYVAR--
Mvan_5576|M.vanbaalenii_PYR-1 -QAQIIAAPTFEFFALYGTAAVYYWVICLVLSFGQARFERRLERYVAK--
MAB_0277c|M.abscessus_ATCC_199 -TAQVAAAPTFQFFTLYVTAGVYYWIVCMAMSAVQDRLEQRLEKSVAR--
MMAR_0061|M.marinum_M FQVGRDLNAQTGNLSPLVAAGIFYLMLTVPLTHLVNYIDARLRRGRRRLD
MAV_0059|M.avium_104 FQVGRDLNAETGNLSPLVAAGACYLILTVPLTHLVNMIDARLRRGRAAVD
TH_0515|M.thermoresistible__bu FQVGRDLNAQTGSLSPLVAAGLFYLALTIPLTHLVNYVDNRLRRGRK-PA
MSMEG_3442|M.smegmatis_MC2_155 --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 -----------------
Rv0411c|M.tuberculosis_H37Rv -----------------
MUL_2809|M.ulcerans_Agy99 -----------------
MLBr_00303|M.leprae_Br4923 -----------------
Mflv_1232|M.gilvum_PYR-GCK -----------------
Mvan_5576|M.vanbaalenii_PYR-1 -----------------
MAB_0277c|M.abscessus_ATCC_199 -----------------
MMAR_0061|M.marinum_M PEDPPGVVSSTIGEEMT
MAV_0059|M.avium_104 PEEPAEMLT--FGQEIT
TH_0515|M.thermoresistible__bu AEDPLEPAT---AQEMI
MSMEG_3442|M.smegmatis_MC2_155 -----------------