For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTLTAAVAQFAPSEDKAANLDTIVDLLRQAADQNADLVVLPEYAVFTVPTMDDRFVRTAEALDGSSVTRL AQAGAELGLTVIAGINESAGNGKIHNTLVGIQGGEIAAVYRKVHLYDAFGYKESDRVIAADPAIPQLLRV NGFTIGMQTCYDLRFPETSRALVDAGADVIALPAEWVPGPLKEYHWNTLLRARAIENTVYVVAADQIAPA GSGNSVILDPMGIPLAALGEAAGIGVARLERSRLESVRTINPALALRRFRVQPEA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3347 | - | - | 100% (265) | nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase |
| M. smegmatis MC2 155 | MSMEG_0924 | - | 5e-34 | 36.60% (235) | hydrolase, carbon-nitrogen family protein |
| M. smegmatis MC2 155 | MSMEG_0571 | - | 2e-17 | 28.21% (280) | hydrolase, carbon-nitrogen family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0490c | - | 4e-33 | 34.62% (260) | hypothetical protein Mb0490c |
| M. gilvum PYR-GCK | Mflv_0095 | - | 4e-32 | 34.33% (268) | Nitrilase/cyanide hydratase and apolipoprotein |
| M. tuberculosis H37Rv | Rv0480c | - | 4e-33 | 34.62% (260) | amidohydrolase |
| M. leprae Br4923 | MLBr_02449 | - | 6e-33 | 33.94% (274) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_4076 | - | 4e-36 | 36.54% (260) | putative nitrilase/cyanide hydratase |
| M. marinum M | MMAR_0805 | - | 9e-33 | 33.97% (262) | amidohydrolase |
| M. avium 104 | MAV_4670 | - | 3e-35 | 35.85% (265) | carbon-nitrogen hydrolase |
| M. thermoresistible (build 8) | TH_0873 | - | 4e-35 | 36.36% (264) | POSSIBLE AMIDOHYDROLASE |
| M. ulcerans Agy99 | MUL_4548 | - | 1e-33 | 34.35% (262) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_0813 | - | 4e-30 | 33.46% (269) | Nitrilase/cyanide hydratase and apolipoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0805|M.marinum_M -------------------------------MRIALAQILSGTDPTANLE
MUL_4548|M.ulcerans_Agy99 -------------------------------MRIALAQILSGTDPTANLE
MLBr_02449|M.leprae_Br4923 -------------------------------MRIALAQILSGTDPVANLR
Mb0490c|M.bovis_AF2122/97 MRRARRRAQAGLPGSCARRCGALVAGPRLARMRIALAQIRSGTDPAANLQ
Rv0480c|M.tuberculosis_H37Rv -------------------------------MRIALAQIRSGTDPAANLQ
MAV_4670|M.avium_104 -------------------------------MRIALAQILSGTDPAANLA
Mflv_0095|M.gilvum_PYR-GCK ---------------------------MRSGMRIALAQIQSSTDPAANLT
Mvan_0813|M.vanbaalenii_PYR-1 -------------------------------MRIALAQIRGSTDPAENLD
TH_0873|M.thermoresistible__bu -------------------------------MRIALAQIRSGTDPSANLN
MAB_4076|M.abscessus_ATCC_1997 -------------------------------MRIVLAQITSGADPTENLA
MSMEG_3347|M.smegmatis_MC2_155 -----------------------------MTLTAAVAQFAPSEDKAANLD
: .:**: . * **
MMAR_0805|M.marinum_M LVRDYAERAADAGARLVVFPEATMCRFG---VPLGPVAQPLDGPWANGVR
MUL_4548|M.ulcerans_Agy99 LVRDYAERAADAGARLVVFPEATMCRFG---VPLGPVAQPLDGPWANGVR
MLBr_02449|M.leprae_Br4923 LVREYTGQATDAGATLVVFPEATMCRFG---VPLGPVAEPIDGPWANGVR
Mb0490c|M.bovis_AF2122/97 LVGKYAGEAATAGAQLVVFPEATMCRLG---VPLRQVAEPVDGPWANGVR
Rv0480c|M.tuberculosis_H37Rv LVGKYAGEAATAGAQLVVFPEATMCRLG---VPLRQVAEPVDGPWANGVR
MAV_4670|M.avium_104 LVGEYTRRAAGAGARLVVFPEATMCRFG---VPLAPIAEPVDGPWADGVR
Mflv_0095|M.gilvum_PYR-GCK LVEEYTRRAVDAGASLVLFPEATMVRFG---VPLGGVAEPFDGPWANAVR
Mvan_0813|M.vanbaalenii_PYR-1 LVEEYTGRAAEAGASLVLFPEATICRFG---VPPAEIAEPFDGPWASAVR
TH_0873|M.thermoresistible__bu LVEEYTRRAAATGAGLVLFPEATMCRFG---VSLKPVAEPLDGPWATAVR
MAB_4076|M.abscessus_ATCC_1997 TVAATVRDAAAQGATLIVFPEATMCRFG---VPLGPVAQPVNGRWADGVR
MSMEG_3347|M.smegmatis_MC2_155 TIVDLLRQAADQNADLVVLPEYAVFTVPTMDDRFVRTAEALDGSSVTRLA
: *. .* *:::** :: . *:..:* . :
MMAR_0805|M.marinum_M RIAAQTGITVVAGMFTPADAG-RVSNTLFAAGPGAPNQPDDHYHKIHLYD
MUL_4548|M.ulcerans_Agy99 RIAAQTGITVVAGMFTPADAG-RVSNTLFAAGPGAPNQPDDHYHKIHLYD
MLBr_02449|M.leprae_Br4923 QIATEAGITIIAGIFTPADDG-RVMNTLIAAGPGTPNQPDTHYHKIHLYD
Mb0490c|M.bovis_AF2122/97 RIATEAGITVIAGMFTPTGDG-RVTNTLIAAGPGTPNQPDAHYHKIHLYD
Rv0480c|M.tuberculosis_H37Rv RIATEAGITVIAGMFTPTGDG-RVTNTLIAAGPGTPNQPDAHYHKIHLYD
MAV_4670|M.avium_104 RIATEANVTVIAGMFTPSGDG-RVKNTLLVAN--SDDQAVTHYDKIHLYD
Mflv_0095|M.gilvum_PYR-GCK DIAARAGIVVVAGMFVPSDDG-RSFNTLLATGPGVEAR----YDKIHLYD
Mvan_0813|M.vanbaalenii_PYR-1 GIAARAGVVVVAGMYVPSDDDDRVTNTLIATGPGVDAR----YDKIHLYD
TH_0873|M.thermoresistible__bu EIAAGAGVVVVAGMFTPSGDG-RVTNTLLATGPGVAAH----YHKIHLYD
MAB_4076|M.abscessus_ATCC_1997 AIADEAGLTVVVGMFTPAGDG-RVHNTLLATGPGVDTH----YNKIHLYD
MSMEG_3347|M.smegmatis_MC2_155 QAGAELGLTVIAGINESAGNG-KIHNTLVGIQGGEIAA---VYRKVHLYD
. .:.::.*: .:. . : ***. * *:****
MMAR_0805|M.marinum_M AFGFAESRTVAPGH--EPVVITVDD----VQVGLTVCYDIRFPALYTELA
MUL_4548|M.ulcerans_Agy99 AFGFAESRTVAPGH--EPVVITVDD----FQVGLTVCYDIRFPALYTELA
MLBr_02449|M.leprae_Br4923 AFGFTESRTVTAGH--EPVVITVDD----VQVGLTICYDIRFPALYTELA
Mb0490c|M.bovis_AF2122/97 AFGFTESRTVAPGR--EPVVVVVDG----VRVGLTVCYDIRFPALYTELA
Rv0480c|M.tuberculosis_H37Rv AFGFTESRTVAPGR--EPVVVVVDG----VRVGLTVCYDIRFPALYTELA
MAV_4670|M.avium_104 AFGFTESRTVAPGR--EPVVVGVDG----VRVGLSVCYDIRFPELYTELA
Mflv_0095|M.gilvum_PYR-GCK AFGFLESKTVAPGR--EPVVISVDTESGPVTVGLTLCYDIRFPELYVELA
Mvan_0813|M.vanbaalenii_PYR-1 AFGFSESKTVAPGR--DPVVITVESESGPVKVGLTLCYDIRFPELYVELA
TH_0873|M.thermoresistible__bu AYGFTESRTVAPGS--EPVTIDV----GGVRVGLTTCYDIRFPELYVELA
MAB_4076|M.abscessus_ATCC_1997 AFGFRESATVAPGH--EPVLITVDG----VAVGLTTCYDIRFPGLYTDLA
MSMEG_3347|M.smegmatis_MC2_155 AFGYKESDRVIAADPAIPQLLRVNG----FTIGMQTCYDLRFPETSRALV
*:*: ** * .. * : * . :*: ***:*** *.
MMAR_0805|M.marinum_M RRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGDTA
MUL_4548|M.ulcerans_Agy99 RRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGDTA
MLBr_02449|M.leprae_Br4923 RRGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAVGQADPGGAL
Mb0490c|M.bovis_AF2122/97 RRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGDAR
Rv0480c|M.tuberculosis_H37Rv RRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGDAR
MAV_4670|M.avium_104 RRGAQLIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAAGQADPGGSL
Mflv_0095|M.gilvum_PYR-GCK DRGAEIITAHASWGTGPGKLEQWTLLARARAIDTSSVVAAVGQAYPGDEI
Mvan_0813|M.vanbaalenii_PYR-1 ERGAEIITAHASWGNGPGKIDQWTLLARARAIDTSTVVAAVGQAYPGDEI
TH_0873|M.thermoresistible__bu RRGAELLTVHASWGSGPGKLEQWTLLARARALDTTCVVAAVGQAYPGDEI
MAB_4076|M.abscessus_ATCC_1997 RRGAQVITVSASWAAGTGKWDQWTLLARARAADSTCFVAAADQALPALEA
MSMEG_3347|M.smegmatis_MC2_155 DAGADVIALPAEWVPGPLKEYHWNTLLRARAIENTVYVVAADQIAP----
**:::. *.* *. * :*. * **** :. :.*..* *
MMAR_0805|M.marinum_M SDPGGGSGAPRGVGGSLVASPLGEVVASAGSDPQLVVADIDLAKVGAARD
MUL_4548|M.ulcerans_Agy99 SDPGGGSGAPRGVGGSLVTSPLGEVVASAGSDPQLVVADIDLAKVGAARD
MLBr_02449|M.leprae_Br4923 TDSGPSSAAPTGVGGSLVASPLGEVVASAGTESKLVVADIDVDNVTTARE
Mb0490c|M.bovis_AF2122/97 TGVGASSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDNVAAARD
Rv0480c|M.tuberculosis_H37Rv TGVGASSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDNVAAARD
MAV_4670|M.avium_104 S----ASGAPTGVGGSLVASPLGEVVASAGAQPQLVLADIDVDRVAQARK
Mflv_0095|M.gilvum_PYR-GCK AALG-----PTGVGGSLVASALGEVLASAGDDPELLVCDVDLEAARKARQ
Mvan_0813|M.vanbaalenii_PYR-1 AALG-----PTGVGHSVVASALGEVLASAGADPQLLMCDIDLEAARAARQ
TH_0873|M.thermoresistible__bu AAQG-----PTGVGGSLVASATGEVLAAAGPEPELLVADLDLDAARRARD
MAB_4076|M.abscessus_ATCC_1997 PAHG----SPTGIGGSLLASPTGELIAQAGPDPELIVADLNLGAVAETRK
MSMEG_3347|M.smegmatis_MC2_155 ----------AGSGNSVILDPMGIPLAALGEAAGIGVARLERSRLESVRT
* * *:: .. * :. * . : :. :: .*
MMAR_0805|M.marinum_M NIGVLRNQSRFTQTDKAQSRR-------------------
MUL_4548|M.ulcerans_Agy99 NIGMLRNQSRFTQTDKAQSRR-------------------
MLBr_02449|M.leprae_Br4923 NIAVLRNRSHFA----------------------------
Mb0490c|M.bovis_AF2122/97 RIAVLRNQTDFVQIDKAQSRG-------------------
Rv0480c|M.tuberculosis_H37Rv RIAVLRNQTDFVQIDKAQSRG-------------------
MAV_4670|M.avium_104 TIAALSNRSDFAQVGRAESVG-------------------
Mflv_0095|M.gilvum_PYR-GCK TVAVMQNRSGFAHRGKAESRG-------------------
Mvan_0813|M.vanbaalenii_PYR-1 TVAVMHNRSEAVRSSRERSSPAVRSSRERSSPAVRSSRER
TH_0873|M.thermoresistible__bu TIAVLRNRSDVAQWGKAESVG-------------------
MAB_4076|M.abscessus_ATCC_1997 ILPVLNSSSAE-----------------------------
MSMEG_3347|M.smegmatis_MC2_155 INPALALRRFRVQPEA------------------------
: