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MGARSWIADHDAAGPAGPADTSMMSTSLGGVLAAELDGARESLGCTTEEIVLAALGRAVARTMGEGLLAV DLDSAGSDSVDGGAQSAARRVVVPCVSRRELSGAELLATARATVSTAEAHPRADVSLRINTDGVATVGEY GLCVHVDHSGDSHLRIDWAYDTRNFDRYTVEELSEQFPLALIEVTSG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3168 | - | - | 100% (187) | phenolpthiocerol synthesis type-i polyketide synthase ppse |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2960 | ppsE | 1e-09 | 26.07% (234) | phenolpthiocerol synthesis type-I polyketide synthase PPSE |
M. gilvum PYR-GCK | Mflv_3645 | - | 3e-19 | 34.59% (185) | hypothetical protein Mflv_3645 |
M. tuberculosis H37Rv | Rv2935 | ppsE | 1e-09 | 26.07% (234) | phenolpthiocerol synthesis type-I polyketide synthase PPSE |
M. leprae Br4923 | MLBr_02353 | - | 6e-10 | 24.68% (231) | polyketide synthase |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_1772 | ppsE | 6e-13 | 26.18% (233) | phenolpthiocerol synthesis type-I polyketide synthase PpsE |
M. avium 104 | - | - | - | - | - |
M. thermoresistible (build 8) | TH_3886 | - | 1e-21 | 32.24% (183) | PUTATIVE - |
M. ulcerans Agy99 | MUL_2015 | ppsE | 4e-13 | 26.18% (233) | phenolpthiocerol synthesis type-I polyketide synthase PpsE |
M. vanbaalenii PYR-1 | Mvan_2768 | - | 5e-23 | 40.91% (176) | hypothetical protein Mvan_2768 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_1772|M.marinum_M MSTIPDNAIAVVGMAGKFPGAKDVSTFWSNLRRGKESIVTLSEEELREAG MUL_2015|M.ulcerans_Agy99 MSTIPDNAIAVVGMAGKFPGAKDVSTFWSNLRRGKESIVTLSEEELREAG Mb2960|M.bovis_AF2122/97 -MSIPENAIAVVGMAGRFPGAKDVSAFWSNLRRGKESIVTLSEQELRDAG Rv2935|M.tuberculosis_H37Rv -MSIPENAIAVVGMAGRFPGAKDVSAFWSNLRRGKESIVTLSEQELRDAG MLBr_02353|M.leprae_Br4923 -MITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNG TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M VSDKTLADPSYVRRAPLVDGIDEFDADFFGFPPLAAQVLDPQHRLFLQCA MUL_2015|M.ulcerans_Agy99 VSDKTLADPSYVRRAPLVDGIDEFDADFFGFPPLAAQVLDPQHRLFLQCA Mb2960|M.bovis_AF2122/97 VSDKTLADPAYVRRAPLLDGIDEFDAGFFGFPPLAAQVLDPQHRLFLQCA Rv2935|M.tuberculosis_H37Rv VSDKTLADPAYVRRAPLLDGIDEFDAGFFGFPPLAAQVLDPQHRLFLQCA MLBr_02353|M.leprae_Br4923 VSDKALADPAYVRRAPLLDGIDEFDADFFGLPPLAAQVLDPQHRLFLQCA TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M WHALEDANCDPAKFDGSIGVYGTSSPSGYLLHNLLSHRDPNTVLAEGLNF MUL_2015|M.ulcerans_Agy99 WHALEDANCDPAKFDGSIGVYGTSSPSGYLLHNLLSHRDPNTVLAEGLNF Mb2960|M.bovis_AF2122/97 WHALEDAGADPARFDGSIGVYGTSSPSGYLLHNLLSHRDPNAVLAEGLNF Rv2935|M.tuberculosis_H37Rv WHALEDAGADPARFDGSIGVYGTSSPSGYLLHNLLSHRDPNAVLAEGLNF MLBr_02353|M.leprae_Br4923 WHALEDAGCDPAQFDGSIGVYGTSSPSGYLLHNLLSHRDPHTVLAEGLNF TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M DQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVAVHLACLSLL MUL_2015|M.ulcerans_Agy99 DQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVAVHLACLSLL Mb2960|M.bovis_AF2122/97 DQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVAVHLACLSLL Rv2935|M.tuberculosis_H37Rv DQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVAVHLACLSLL MLBr_02353|M.leprae_Br4923 DQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVALHLACLSLL TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M SGECDVALAGGSSLCVPHHVGYFTSPGSMVSAVGHCRPFDVRSDGTVFGS MUL_2015|M.ulcerans_Agy99 SGECDVALAGGSSLCVPHHVGYFTSPGSMVSAVGHCRPFDVRSDGTVFGS Mb2960|M.bovis_AF2122/97 SGECDMALAGGSSLCIPHRVGYFTSPGSMVSAVGHCRPFDVRADGTVFGS Rv2935|M.tuberculosis_H37Rv SGECDMALAGGSSLCIPHRVGYFTSPGSMVSAVGHCRPFDVRADGTVFGS MLBr_02353|M.leprae_Br4923 SGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDVRADGTVFGS TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M GVAMVVLKPLQAAIDAGDRIHAVIRGSAINNDGSAKMGYAAPNPAAQADV MUL_2015|M.ulcerans_Agy99 GAAMVVLKPLQAAIDAGDRIHAVIRASAINNDGSAKMGYAAPNPAAQADV Mb2960|M.bovis_AF2122/97 GVGLVVLKPLAAAIDAGDRIHAVIRGSAINNDGSAKMGYAAPNPAAQADV Rv2935|M.tuberculosis_H37Rv GVGLVVLKPLAAAIDAGDRIHAVIRGSAINNDGSAKMGYAAPNPAAQADV MLBr_02353|M.leprae_Br4923 GVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPNPAAQADV TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M IAEAHAVSGIDASTVSYVECHGTGTPLGDPIEIQGLRTAFEASETTRTGP MUL_2015|M.ulcerans_Agy99 IAEAHAVSGIDASTVSYVECHGTGTPLGDPIEIQGLRTAFEASETTRTGP Mb2960|M.bovis_AF2122/97 IAEAHAVSGIDSSTVSYVECHGTGTPLGDPIEIQGLRAAFEVSQTSRSAP Rv2935|M.tuberculosis_H37Rv IAEAHAVSGIDSSTVSYVECHGTGTPLGDPIEIQGLRAAFEVSQTSRSAP MLBr_02353|M.leprae_Br4923 IAEAHAVAGIDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGP TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M CVLGSVKSNIGHLEVAAGIAGLIKTILCLKNRAIPATLHYTSPNPELRLE MUL_2015|M.ulcerans_Agy99 CVLGSVKSNIGHLEVAAGIAGLIKTILCLKNRAIPATLHYTSPNPELRLE Mb2960|M.bovis_AF2122/97 CVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKALPATLHYTSPNPELRLD Rv2935|M.tuberculosis_H37Rv CVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKALPATLHYTSPNPELRLD MLBr_02353|M.leprae_Br4923 CVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKAIPATLHYTSPNRELRLD TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M QSPFVVQNKYGPWEWDGVLRAGVSSFGVGGTNAHVVLEEAP----TVPAH MUL_2015|M.ulcerans_Agy99 QSPFVVQNKYGPWEWDGVLRAGVSSFGVGGTNAHVVLEEAP----TVPAH Mb2960|M.bovis_AF2122/97 QSPFVVQSKYGPWECDGVRRAGVSSFGVGGTNAHVVLEEAPAEASEVSAH Rv2935|M.tuberculosis_H37Rv QSPFVVQSKYGPWECDGVRRAGVSSFGVGGTNAHVVLEEAPAEASEVSAH MLBr_02353|M.leprae_Br4923 QTPFVVQSNYGPWKWDGVRRAGVSSFGVGGTNVHVVLEEASVEASTVAAS TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M DEPAGPQVLLLSAQTAAALTESRTALAEVLERSDSPDLSDVAYTLSRRRK MUL_2015|M.ulcerans_Agy99 DEPAGPQVLLLSAQTAAALTESRTALAEVLGRSDSPDLSDVAYTLSRRRK Mb2960|M.bovis_AF2122/97 AEPAGPQVILLSAQTAAALGESRTALAAALETQDGPRLSDVAYTLARRRK Rv2935|M.tuberculosis_H37Rv AEPAGPQVILLSAQTAAALGESRTALAAALETQDGPRLSDVAYTLARRRK MLBr_02353|M.leprae_Br4923 ---TGPQVILLSAQTAAALGESREALATVLEKPGAPDLSDVAYTLAGRRK TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M HNVTMAAVVSDREEAATALRAADNDSIFVGESVAG-----VADATAAAAE MUL_2015|M.ulcerans_Agy99 HNVTMAAVVSDREEAATALRAADNDSIFVGESVAG-----VADATAAAAE Mb2960|M.bovis_AF2122/97 HNVTMAAVVHDREHAATVLRAAEHDNVFVGEAAHDGEHGDRADAAPT-SD Rv2935|M.tuberculosis_H37Rv HNVTMAAVVHDREHAATVLRAAEHDNVFVGEAAHDGEHGDRADAAPT-SD MLBr_02353|M.leprae_Br4923 HNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASITTLGSD TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M RVVFLFPGQGAQHVGMAKGLYETEPVFAEHFDACAAGFRAEMG-VDLNAE MUL_2015|M.ulcerans_Agy99 RVVFLFPGQGAQHVGMAKGLYETEPVFAEHFDACAAGFRAEMG-VDLNAE Mb2960|M.bovis_AF2122/97 RVVFLFPGQGAQHVGMAKGLYDTEPVFAQHFDTCAAGFRDETG-IDLHAE Rv2935|M.tuberculosis_H37Rv RVVFLFPGQGAQHVGMAKGLYDTEPVFAQHFDTCAAGFRDETG-IDLHAE MLBr_02353|M.leprae_Br4923 RVVFLFPGQGAQHVGMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSA TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M IFNGTATDLERIDRSQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYIA MUL_2015|M.ulcerans_Agy99 IFNGTGTDLERIDRSQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYIA Mb2960|M.bovis_AF2122/97 VFDGTATDLERIDRSQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYIA Rv2935|M.tuberculosis_H37Rv VFDGTATDLERIDRSQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYIA MLBr_02353|M.leprae_Br4923 IFNGTAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYIA TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M ATLAGVFDLETAIKTVSLRARLMHESPPGAMVAVAVGPDEIAQYLGD--- MUL_2015|M.ulcerans_Agy99 ATLAGVFDLETAIKTVSLRARLMHESPPGAMVAVAVGPDDFAQYLGD--- Mb2960|M.bovis_AF2122/97 ATLAGVFDLQTAIKTVSLRARLMHESPPGAMVAVALGPDDVTQYLPP--- Rv2935|M.tuberculosis_H37Rv ATLAGVFDLQTAIKTVSLRARLMHESPPGAMVAVALGPDDVTQYLPP--- MLBr_02353|M.leprae_Br4923 ATLAGVFDLETAIKTVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSA TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M -GVELSAVNDPGNCVVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHSSS MUL_2015|M.ulcerans_Agy99 -GVELSAVNDPGNCVVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHSSS Mb2960|M.bovis_AF2122/97 -EVELSAVNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSA Rv2935|M.tuberculosis_H37Rv -EVELSAVNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSA MLBr_02353|M.leprae_Br4923 KGVELSAVNDPGNCVVAGPKDQIRAFSQRLDEVGIPVRRVRATHAFHTSS TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M MEPMLGEFQEFLSRQQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQISS MUL_2015|M.ulcerans_Agy99 MEPMLGEFQEFLSRQQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQISS Mb2960|M.bovis_AF2122/97 MDPMLGQFQEFLSRQQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQISS Rv2935|M.tuberculosis_H37Rv MDPMLGQFQEFLSRQQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQISS MLBr_02353|M.leprae_Br4923 MEPMLREFSEFLSRQQLRVPNTPLLSNLTGTWMSEQQVTDPENWTRQISS TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M TVRFADELDVVLSQPNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRLMRH MUL_2015|M.ulcerans_Agy99 TVRFADELDVVLSQPNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRLMRH Mb2960|M.bovis_AF2122/97 PIRFADELDVVLAAPSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRLMRH Rv2935|M.tuberculosis_H37Rv PIRFADELDVVLAAPSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRLMRH MLBr_02353|M.leprae_Br4923 TIRFADELDVVLSQSGRVLVEVGPGGSLTGSAMRHPRWSSGHRAVRLMRH TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M PIQNLDDRETFLRALGELWSAGVDVDWTPRRAASPRIVSLPGYPFARQRH MUL_2015|M.ulcerans_Agy99 PIQNLDDRETFLRALGELWSAGVDVDWTPRRAASPRIVSLPGYPFARQRH Mb2960|M.bovis_AF2122/97 PLQDVDDRDTFLRALGELWSAGVEVDWTPRRPAVPHLVSLPGYPFARQRH Rv2935|M.tuberculosis_H37Rv PLQDVDDRDTFLRALGELWSAGVEVDWTPRRPAVPHLVSLPGYPFARQRH MLBr_02353|M.leprae_Br4923 PLQNVDDHDTFLRALGELWSAGIEVDWAPQRSVMPHLVSLPGYPFARQRH TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M WVEPKHMAWAQIPTASNGSSVGAKLGSGADSGIRGGAQTGESQTEDVLQR MUL_2015|M.ulcerans_Agy99 WVEPKHMAWAQIPTASNGSSVGAKLGSGADSGIRGGAQTGESQTEDVLQR Mb2960|M.bovis_AF2122/97 WVEPNHTVWAQAPGANNGSPAGTADGSTA--ATVDAARNGESQTEVTLQR Rv2935|M.tuberculosis_H37Rv WVEPNHTVWAQAPGANNGSPAGTADGSTA--ATVDAARNGESQTEVTLQR MLBr_02353|M.leprae_Br4923 WVEPRYTIWAQIPGASSGSPVDSSVDS----ATVEGVRGGESQTEATLQR TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M IWSQCLGVGSVDRNANFFDMGGDSLMAISIAMSAANEGLTITPQDLYEHP MUL_2015|M.ulcerans_Agy99 IWSQCLGVGSVDRNANFFDMGGDSLMAISIAMSAANEGLTITPQDLYEHP Mb2960|M.bovis_AF2122/97 IWSQCLGVSSVDRNANFFDLGGDSLMAISIAMAAANEGLTITPQDLYEYP Rv2935|M.tuberculosis_H37Rv IWSQCLGVSSVDRNANFFDLGGDSLMAISIAMAAANEGLTITPQDLYEYP MLBr_02353|M.leprae_Br4923 IWSQCLGVSSVDRNANFFDLGGDSLMAISISMAAANEGMTITPQDMYEHP TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M TLASLTAAIDASFASSGLAKPPEADANPAVPPNIAYFLDRGLRDTGRWRV MUL_2015|M.ulcerans_Agy99 TLASLTAAIDASFASSGLAKPPEADANPAVPPNIAYFLDRGLRDTGRWRV Mb2960|M.bovis_AF2122/97 TLASLTAAVDASFASSGLAKPPEAQANPAVPPNVTYFLDRGLRDTGRCRV Rv2935|M.tuberculosis_H37Rv TLASLTAAVDASFASSGLAKPPEAQANPAVPPNVTYFLDRGLRDTGRCRV MLBr_02353|M.leprae_Br4923 TLASLTAAVDASFASSGLAKPPEAAAHPAVPPNIAYFLERGLCDTGRWRV TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M PLILRLDPQVGPEDIRAVLSAVTNHHDALRLRLVENGGVWEQHIAAPADF MUL_2015|M.ulcerans_Agy99 PLILRLDPQVGPEDIRAVLSAVTNHHDALRLRLVENGGVWEQHIAAPADF Mb2960|M.bovis_AF2122/97 PLILRLDPKIGLPDIRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEF Rv2935|M.tuberculosis_H37Rv PLILRLDPKIGLPDIRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEF MLBr_02353|M.leprae_Br4923 PLILRLDPKIGSDDIRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEF TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M TELATRQLPGDLAAGEADEHGAVSNIVAELIAEQGDSNAPLIAVHVTAPN MUL_2015|M.ulcerans_Agy99 TELATRQLPDDLAADEADEHSAVSNIVAELIAEQGDSNAPLIAVHVTAPN Mb2960|M.bovis_AF2122/97 TGLSNRSVPDGVAAGSPEERAAVLGILAELLEDQTDPNAPLAAVHIAAAH Rv2935|M.tuberculosis_H37Rv TGLSNRSVPNGVAAGSPEERAAVLGILAELLEDQTDPNAPLAAVHIAAAH MLBr_02353|M.leprae_Br4923 TRLLTQTLPDGVAAGSAEERAVVSSILAELIASQSDLNEPLTAVQITTAH TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M GGAQYLGLALHEMVADDASRQLLGADIITAFAQRLGDQEIKLDPVTTGWR MUL_2015|M.ulcerans_Agy99 GGAQYLGLALHETVADDASRQLLGADIITAFAQRLDDQEIKLDPVTTGWR Mb2960|M.bovis_AF2122/97 GGPHYLCLAIHAMVTDDSSRQILATDIVTAFGQRLAGEEITLEPVSTGWR Rv2935|M.tuberculosis_H37Rv GGPHYLCLAIHAMVTDDSSRQILATDIVTAFGQRLAGEEITLEPVSTGWR MLBr_02353|M.leprae_Br4923 GGPHYLGLAVHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGWR TH_3886|M.thermoresistible__bu -------------------------------------------------- Mflv_3645|M.gilvum_PYR-GCK -------------------------------------------------M Mvan_2768|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3168|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_1772|M.marinum_M DWSVRCAALATHPAALDTRSYWIEQSTKANLWLTDG----DAAQPPSATD MUL_2015|M.ulcerans_Agy99 DWSVRCAALATHPAALDTRSYWIEQSTKANLWLTDG----DAAQPPSATD Mb2960|M.bovis_AF2122/97 EWSLRCAALATHPAALDTRSYWIENSTKATLWLADALPNAHTAHPPRADE Rv2935|M.tuberculosis_H37Rv EWSLRCAALATHPAALDTRSYWIENSTKATLWLADALPNAHTAHPPRADE MLBr_02353|M.leprae_Br4923 EWSLRCAALATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADD TH_3886|M.thermoresistible__bu -------MVAPSFARLDTEYLRLTDH--------------DVADPPRPED Mflv_3645|M.gilvum_PYR-GCK GHSLYGKAMVAPYITGEVKQRPLRSAPAALDVFDHS------SIDALPHQ Mvan_2768|M.vanbaalenii_PYR-1 --------MVAPYISDEVKPRPVPSVPEILDVFDRP------AADALPAR MSMEG_3168|M.smegmatis_MC2_155 -------MGARSWIADHDAAGPAG-----------------------PAD . . . MMAR_1772|M.marinum_M LTKLPSVLNAEQTSELDDARRRFRRSIQTILLAALGRTIAQTVGDGVVAV MUL_2015|M.ulcerans_Agy99 LTKLPSVLNAEQTSELDDARRRFRRSIQTILLAALGRTIAQTVGDGVVAV Mb2960|M.bovis_AF2122/97 LTKLSSTLSVEQTSELDDGRRRFRRSIQTILLAALGRTIAQTVGEGVVAV Rv2935|M.tuberculosis_H37Rv LTKLSSTLSVEQTSELDDGRRRFRRSIQTILLAALGRTIAQTVGEGVVAV MLBr_02353|M.leprae_Br4923 LIRMPCTLSVEQTSELDDARRRFRRSIQAIVLAALGRTIAQTVGDGVVAV TH_3886|M.thermoresistible__bu LVRHPAPLSPVLSGELDGAAQALDSSAEELLLAALARTIGRTIGTGTVVV Mflv_3645|M.gilvum_PYR-GCK LEKFSTTPSSELTEEVEASAEWLGVPIEEILLAALGRTLGRTRGEGNITI Mvan_2768|M.vanbaalenii_PYR-1 SQKFGTSSSSELTEELDGAAEWLGVRVEEILLAALGRTFGRTRGEGAVDV MSMEG_3168|M.smegmatis_MC2_155 TSMMSTSLGGVLAAELDGARESLGCTTEEIVLAALGRAVARTMGEGLLAV . : *:: . . : : ::****.*:..:* * * : : MMAR_1772|M.marinum_M ELDGEGRSVLRPDVDVRRTVGRFTTYYPVALTCATGQGAAALKGLDAVHD MUL_2015|M.ulcerans_Agy99 ELDGEGRSVLRPDVDVRRTVGRFTTYYPVALTCATGQGAAALKGLDAVHD Mb2960|M.bovis_AF2122/97 ELEGEGRSVLRPDVDLRRTVGWFTTYYPVPLACATGLG--ALAQLDAVHN Rv2935|M.tuberculosis_H37Rv ELEGEGRSVLRPDVDLRRTVGWFTTYYPVPLACATGLG--ALAQLDAVHN MLBr_02353|M.leprae_Br4923 ELEGEGRSVLRPDVDVRRTIGWFTNYYPIPLVCVKGQG--ALAQLDAVHN TH_3886|M.thermoresistible__bu GLADHG---------------------PLALACATEKTISATDLLTGVRS Mflv_3645|M.gilvum_PYR-GCK DVT----------------GGNRWLSQPAAIFCSADPALSPTDILQSAHT Mvan_2768|M.vanbaalenii_PYR-1 DVT----------------GGHRWASRPVSMICAAGQPMGPTEMLQGAHS MSMEG_3168|M.smegmatis_MC2_155 DLDSAGSDSV--------DGGAQSAARRVVVPCVSRRELSGAELLATARA : : * * .: MMAR_1772|M.marinum_M TLKSVPHYGIGYGLLRYLYAPTGRVLGAQRTPDIHFRYAGTIPELPPVDA MUL_2015|M.ulcerans_Agy99 TLKSVPHYGIGYGLLRYLYAPTGRVLGAQRTPDIHFRYAGTIPELPPVDA Mb2960|M.bovis_AF2122/97 TLKSVPHYGIGYGLLRYVYAPTGRVLGAQRTPDIHFRYAGVIPELPSGDA Rv2935|M.tuberculosis_H37Rv TLKSVPHYGIGYGLLRYVYAPTGRVLGAQRTPDIHFRYAGVIPELPSGDA MLBr_02353|M.leprae_Br4923 TLKSIPHYGIGYGLLRYMYAPTGRVFSAQRTPDIHFRYVGVVPEPPSVDA TH_3886|M.thermoresistible__bu SLG-------------------ARTPAAGGAREIAVTFSGPVSELPD--- Mflv_3645|M.gilvum_PYR-GCK ALVS------------------SPRRSAEPADVLLNVSVGSLLDAPAG-- Mvan_2768|M.vanbaalenii_PYR-1 VLAG------------------APFRAGAQSEVLLNVANG-VVDRPCT-- MSMEG_3168|M.smegmatis_MC2_155 TVST------------------AEAHP--RADVSLRINTDGVATVGEY-- : . : . : MMAR_1772|M.marinum_M PVQFDSDLAMPVREPLPGLGHAVEIRAYRSGSSLHVDWWYDTRRITAETA MUL_2015|M.ulcerans_Agy99 PVQFDSDLAMPVREPLPGLGHAVEIRAYRSGSSLHVDWWYDTRRITAETA Mb2960|M.bovis_AF2122/97 PVQFDSDMTLPVREPIPGMGHAIELRVYRFGGSLHLDWWYDTRRIPAATA Rv2935|M.tuberculosis_H37Rv PVQFDSDMTLPVREPIPGMGHAIELRVYRFGGSLHLDWWYDTRRIPAATA MLBr_02353|M.leprae_Br4923 TVQFDSDMTIPVQEPVPGMGHAIELRTYRFGGSLHLDWWYDIRRIPQVTA TH_3886|M.thermoresistible__bu -----------------SPCHAIELRIHRSHDRVHLDWWYDPARFYPYTV Mflv_3645|M.gilvum_PYR-GCK --------------------RALELRVQRLDGGLQIDWWYDAQRFDPYSI Mvan_2768|M.vanbaalenii_PYR-1 --------------------RPLELRVQRVDGLLQIDWWYDESRLDAYSV MSMEG_3168|M.smegmatis_MC2_155 --------------------GLCVHVDHSGDSHLRIDWAYDTRNFDRYTV . :::** ** .: : MMAR_1772|M.marinum_M TALARSFPTALSELIQESIAAEQEERDEDEKVGVIEAGALVDLSSLDAG MUL_2015|M.ulcerans_Agy99 TALARSFPTALSELIQESIAAEQEERDEDEKVGVIEAGALVDLPSLDAG Mb2960|M.bovis_AF2122/97 EALERTFPLALSALIQEAIAAEHTEHDDSEIVGEPEAGALVDLSSMDAG Rv2935|M.tuberculosis_H37Rv EALERTFPLALSALIQEAIAAEHTEHDDSEIVGEPEAGALVDLSSMDAG MLBr_02353|M.leprae_Br4923 EALAQSFPVTLSKLIQEGIATQKDAHDESEMAGAPQAGVLVDLSTLDAG TH_3886|M.thermoresistible__bu VELAEQFPLALIEVCSEATVPSVPRPARSLICTAP-------------- Mflv_3645|M.gilvum_PYR-GCK EEMAEQFPQAVIDITSDASAPL--------------------------- Mvan_2768|M.vanbaalenii_PYR-1 EEMAEQFPLAAIEITSDAAAPL--------------------------- MSMEG_3168|M.smegmatis_MC2_155 EELSEQFPLALIEVTSG-------------------------------- : . ** : : .